Sample overview of LS180

Sample ID: Sample_02_358
Biosample type: Cell line
Tissue type: Colon
Biosample name: LS180
Data source: NCBI GEO/SRA
GSE ID: GSE73319
Cancer type: Colorectal Cancer
CRC number: 2532
TF number of all CRCs: 59
TF list of all CRCs: HOXA10, CDX2, HOXA9, EHF, KLF5, HNF1A, HOXA7, HOXA11, TFAP2A, RARA, HOXB8, SP1, TGIF1, ASCL2, SOX13, FOXA1, RUNX1, VDR, HOXB3, ETV4, BHLHE40, RREB1, FOXQ1, HOXB4, SOX4, HOXB5, SREBF1, ELF3, RUNX2, FOSL2, HOXB6, KLF16, HES1, DLX1, KLF3, HOXB7, ZBTB7B, GATA6, YY1, SOX9, MYC, BARX2, ETS2, NR2F6, CEBPA, NR2F2, JUNB, HOXA13, MEF2D, ERF, MNX1, ZBTB7A, ETV3, SP3, DEAF1, MNT, NFE2L2, FOSL1, MAFG

The most representative CRC of LS180
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Relationship plot of CRC model
TF number of this CRC: 22
CRC socre: 1776.773
TF list of the most representative CRC
TF name TF family Frequency of TFs
ASCL2 bHLH 1577 / 2532
CDX2 Homeobox 2521 / 2532
EHF ETS 2445 / 2532
FOXA1 Fork_head 1559 / 2532
HES1 bHLH 586 / 2532
HNF1A Homeobox 2303 / 2532
HOXA10 Homeobox 2521 / 2532
HOXA11 Homeobox 2177 / 2532
HOXA7 Homeobox 2197 / 2532
HOXA9 Homeobox 2521 / 2532
HOXB3 Homeobox 1025 / 2532
HOXB5 Homeobox 755 / 2532
HOXB8 Homeobox 1936 / 2532
KLF5 zf-C2H2 2358 / 2532
RARA THR-like 2006 / 2532
RREB1 zf-C2H2 909 / 2532
RUNX1 Runt 1361 / 2532
SOX13 HMG 1574 / 2532
SP1 zf-C2H2 1844 / 2532
TFAP2A AP-2 2077 / 2532
TGIF1 Homeobox 1801 / 2532
VDR THR-like 1036 / 2532

All CRCs of LS180
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
CDX2 2521 / 2532 Homeobox ENSG00000165556
HOXA10 2521 / 2532 Homeobox ENSG00000253293
HOXA9 2521 / 2532 Homeobox ENSG00000078399
EHF 2445 / 2532 ETS ENSG00000135373
KLF5 2358 / 2532 zf-C2H2 ENSG00000102554
HNF1A 2303 / 2532 Homeobox ENSG00000135100
HOXA7 2197 / 2532 Homeobox ENSG00000122592
HOXA11 2177 / 2532 Homeobox ENSG00000005073
TFAP2A 2077 / 2532 AP-2 ENSG00000137203
RARA 2006 / 2532 THR-like ENSG00000131759
HOXB8 1936 / 2532 Homeobox ENSG00000120068
SP1 1844 / 2532 zf-C2H2 ENSG00000185591
TGIF1 1801 / 2532 Homeobox ENSG00000177426
ASCL2 1577 / 2532 bHLH ENSG00000183734
SOX13 1574 / 2532 HMG ENSG00000143842
FOXA1 1559 / 2532 Fork_head ENSG00000129514
RUNX1 1361 / 2532 Runt ENSG00000159216
VDR 1036 / 2532 THR-like ENSG00000111424
HOXB3 1025 / 2532 Homeobox ENSG00000120093
ETV4 960 / 2532 ETS ENSG00000175832
BHLHE40 956 / 2532 bHLH ENSG00000134107
RREB1 909 / 2532 zf-C2H2 ENSG00000124782
FOXQ1 871 / 2532 Fork_head ENSG00000164379
HOXB4 848 / 2532 Homeobox ENSG00000182742
SOX4 760 / 2532 HMG ENSG00000124766
HOXB5 755 / 2532 Homeobox ENSG00000120075
SREBF1 700 / 2532 bHLH ENSG00000072310
ELF3 686 / 2532 ETS ENSG00000163435
RUNX2 630 / 2532 Runt ENSG00000124813
FOSL2 628 / 2532 TF_bZIP ENSG00000075426
HOXB6 610 / 2532 Homeobox ENSG00000108511
KLF16 587 / 2532 zf-C2H2 ENSG00000129911
HES1 586 / 2532 bHLH ENSG00000114315
DLX1 568 / 2532 Homeobox ENSG00000144355
KLF3 544 / 2532 zf-C2H2 ENSG00000109787
HOXB7 477 / 2532 Homeobox ENSG00000260027
ZBTB7B 472 / 2532 ZBTB ENSG00000160685
GATA6 443 / 2532 zf-GATA ENSG00000141448
YY1 434 / 2532 zf-C2H2 ENSG00000100811
SOX9 425 / 2532 HMG ENSG00000125398
MYC 385 / 2532 bHLH ENSG00000136997
BARX2 340 / 2532 Homeobox ENSG00000043039
ETS2 337 / 2532 ETS ENSG00000157557
NR2F6 286 / 2532 RXR-like ENSG00000160113
CEBPA 282 / 2532 TF_bZIP ENSG00000245848
NR2F2 272 / 2532 RXR-like ENSG00000185551
JUNB 265 / 2532 TF_bZIP ENSG00000171223
HOXA13 250 / 2532 Homeobox ENSG00000106031
MEF2D 241 / 2532 SRF ENSG00000116604
ERF 219 / 2532 ETS ENSG00000105722
MNX1 218 / 2532 Homeobox ENSG00000130675
ZBTB7A 174 / 2532 ZBTB ENSG00000178951
ETV3 153 / 2532 ETS ENSG00000117036
SP3 88 / 2532 zf-C2H2 ENSG00000172845
DEAF1 87 / 2532 SAND ENSG00000177030
MNT 80 / 2532 bHLH ENSG00000070444
NFE2L2 66 / 2532 TF_bZIP ENSG00000116044
FOSL1 57 / 2532 TF_bZIP ENSG00000175592
MAFG 11 / 2532 TF_bZIP ENSG00000197063

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
VDR 59 80 139
YY1 52 76 128
FOXQ1 62 70 132
HOXA13 49 78 127
JUNB 56 69 125
MEF2D 50 70 120
ERF 57 58 115
SOX9 51 80 131
SOX13 62 75 137
ELF3 56 79 135
MNX1 51 67 118
SOX4 53 78 131
MAFG 39 53 92
RARA 59 78 137
FOXA1 61 70 131
CEBPA 60 59 119
RUNX1 59 79 138
KLF16 55 78 133
TFAP2A 61 80 141
NFE2L2 42 72 114
DEAF1 47 60 107
HOXA11 65 74 139
NR2F2 47 72 119
ETS2 65 56 121
HOXA10 65 78 143
KLF5 64 80 144
HNF1A 64 75 139
KLF3 57 72 129
FOSL2 62 65 127
FOSL1 40 70 110
MYC 58 69 127
RREB1 57 80 137
DLX1 59 64 123
HOXB8 65 69 134
CDX2 65 77 142
ZBTB7A 60 54 114
ZBTB7B 59 71 130
ASCL2 61 79 140
SP1 60 80 140
SP3 35 77 112
HOXB6 65 51 116
HOXB4 65 53 118
HOXB5 65 57 122
EHF 65 79 144
HOXB7 65 52 117
GATA6 62 64 126
NR2F6 47 79 126
HOXB3 65 62 127
RUNX2 54 76 130
BARX2 58 49 107
ETV3 59 51 110
MNT 61 45 106
ETV4 61 75 136
HOXA7 65 71 136
BHLHE40 63 68 131
SREBF1 59 74 133
HOXA9 65 77 142
HES1 59 66 125
TGIF1 61 75 136

Expression of TFs in all CRCs