TF information

TF name: ETV3
TF family: ETS
Ensembl gene ID: ENSG00000117036
Ensembl protein ID: ENSP00000357175, ENSP00000327316
Entrez gene ID: 2117
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of ETV3 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_181Cell lineHuman melanomaCOLO6790.10293333333333
Sample_02_184Cell lineSkinSKMEL300.2379421221865
Sample_02_304Cell lineNeuroblastomaN2060.08695652173913
Sample_02_319Cell lineNeuroblastomaNB-EBc10.063583815028902
Sample_02_356Cell lineColonSw4800.16774193548387
Sample_02_358Cell lineColonLS1800.06042654028436

ETV3 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name

ETV3 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with ETV3
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Mutation of ETV3
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of ETV3

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr1157105442157105442GAexonicETV3synonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr1157103991157103991TCexonicETV3nonsynonymous SKCM|1|368|0.00272
-chr1157106124157106124GAexonicETV3synonymous LUAD|1|543|0.00184
-chr1157105362157105362CGexonicETV3nonsynonymous PRAD|1|499|0.00200
-chr1157095749157095749TCexonicETV3synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1157105486157105486CTexonicETV3nonsynonymous BLCA|1|396|0.00253
-chr1157094757157094757GAexonicETV3nonsynonymous UCEC|1|248|0.00403
-chr1157095477157095477GTexonicETV3nonsynonymous UCEC|1|248|0.00403
-chr1157105467157105467TAexonicETV3nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr1157095097157095097CTexonicETV3nonsynonymous BRCA|1|982|0.00102
-chr1157105373157105373CAexonicETV3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1157095675157095675GAexonicETV3nonsynonymous UCEC|1|248|0.00403
-chr1157095727157095727GAexonicETV3nonsynonymous BRCA|1|982|0.00102
-chr1157095426157095426AGexonicETV3nonsynonymous UCEC|1|248|0.00403
-chr1157105292157105292CTexonicETV3nonsynonymous LUSC|1|178|0.00562
-chr1157104020157104020CAsplicingETV3splicing LUSC|1|178|0.00562
-chr1157105324157105324GAexonicETV3nonsynonymous SKCM|1|368|0.00272
-chr1157106102157106102CGexonicETV3nonsynonymous LUAD|1|543|0.00184
-chr1157095156157095156GTexonicETV3stopgain UCEC|1|248|0.00403
-chr1157105317157105317CTexonicETV3nonsynonymous PRAD|1|499|0.00200
-chr1157095480157095480ACexonicETV3nonsynonymous UCEC|1|248|0.00403
-chr1157094741157094741CTexonicETV3synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs2231852chr1157106152157106152CTUTR5ETV3unknown STAD|1|395|0.00253,STES|1|395|0.00253
-chr1157094985157094985GAexonicETV3nonsynonymous TGCT|1|155|0.00645
-chr1157095391157095391CAexonicETV3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1157105325157105325GAexonicETV3synonymous SKCM|1|368|0.00272
-chr1157095505157095505GTexonicETV3nonsynonymous ESCA|1|185|0.00541
-chr1157106111157106111CTexonicETV3nonsynonymous BRCA|1|982|0.00102
-chr1157103994157103994GAexonicETV3nonsynonymous SKCM|1|368|0.00272
rs763695411chr1157094737157094737GAexonicETV3nonsynonymous ESCA|1|185|0.00541
-chr1157095428157095428AGexonicETV3synonymous TGCT|1|155|0.00645
-chr1157104016157104016-TexonicETV3stopgain PRAD|1|499|0.00200
-chr1157103875157103875ACexonicETV3nonsynonymous UCEC|1|248|0.00403
-chr1157104017157104017TCexonicETV3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1157104014157104014TCexonicETV3nonsynonymous PRAD|1|499|0.00200
-chr1157095708157095708AGexonicETV3nonsynonymous UCEC|1|248|0.00403
-chr1157106116157106116T-exonicETV3frameshift COAD|2|367|0.00545,COADREAD|2|489|0.00409
-chr1157103988157103988TGexonicETV3nonsynonymous LIHC|1|373|0.00268
-chr1157105282157105282TAexonicETV3stopgain PRAD|1|499|0.00200
-chr1157106140157106140TGexonicETV3nonsynonymous LUAD|1|543|0.00184
rs762200550chr1157105311157105311CTexonicETV3nonsynonymous LAML|1|197|0.00508
-chr1157095225157095225GTexonicETV3nonsynonymous UCEC|1|248|0.00403
-chr1157105452157105452GAexonicETV3nonsynonymous BRCA|1|982|0.00102
-chr1157094756157094756G-exonicETV3frameshift ESCA|1|185|0.00541
-chr1157103900157103900TGexonicETV3nonsynonymous UCEC|1|248|0.00403
-chr1157095349157095349AGexonicETV3nonsynonymous LIHC|1|373|0.00268
-chr1157105334157105334CTexonicETV3synonymous HNSC|1|512|0.00195
-chr1157095521157095521TCexonicETV3synonymous LIHC|1|373|0.00268
-chr1157104005157104005TCexonicETV3nonsynonymous LIHC|1|373|0.00268
rs775605192chr1157105270157105270CTexonicETV3nonsynonymous SARC|1|247|0.00405
-chr1157095223157095223GAexonicETV3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1157103953157103953GTexonicETV3nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr1157105388157105388GAexonicETV3synonymous SKCM|1|368|0.00272
-chr1157095415157095415GAexonicETV3nonsynonymous LIHC|1|373|0.00268
-chr1157105447157105447GAexonicETV3stopgain UCEC|1|248|0.00403

Disease information of ETV3
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
ETV3 Prostatic Neoplasms C04;C12 Neoplastic Process CTD_human
ETV3 Malignant neoplasm of prostate C04;C12 Neoplastic Process CTD_human

Pathway associated with ETV3
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0001604 PDGF signaling pathway panther 113 1684

Go term information of ETV3
GO_term_name GO_term_type TF_name
GO_NEGATIVE_REGULATION_OF_CELL_PROLIFERATION BP ETV3
GO_NUCLEAR_TRANSCRIPTIONAL_REPRESSOR_COMPLEX CC ETV3
GO_TRANSCRIPTIONAL_REPRESSOR_COMPLEX CC ETV3
GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY_SEQUENCE_SPECIFIC_DNA_BINDING MF ETV3

Survival analysis of ETV3



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of ETV3