Sample overview of SKMEL30

Sample ID: Sample_02_184
Biosample type: Cell line
Tissue type: Skin
Biosample name: SKMEL30
Data source: NCBI GEO/SRA
GSE ID: GSE75352
Cancer type: melanoma
CRC number: 311
TF number of all CRCs: 31
TF list of all CRCs: RARA, TGIF1, SOX10, RREB1, POU3F1, RUNX3, TFAP2C, FOXD3, ETV4, MEF2D, TBX2, SMAD3, PKNOX2, NR4A2, SOX5, MAFB, SOX13, ETV3, SNAI2, TFAP2A, HES1, FOXD2, ETV5, JUNB, BHLHE40, IRF4, MITF, MEF2C, SREBF1, ARID5B, MNT

The most representative CRC of SKMEL30
Download
Relationship plot of CRC model
TF number of this CRC: 12
CRC socre: 174.33333
TF list of the most representative CRC
TF name TF family Frequency of TFs
ETV4 ETS 150 / 311
FOXD3 Fork_head 152 / 311
MAFB TF_bZIP 109 / 311
MEF2D SRF 150 / 311
PKNOX2 Homeobox 116 / 311
POU3F1 Pou 188 / 311
RARA THR-like 280 / 311
RREB1 zf-C2H2 191 / 311
RUNX3 Runt 180 / 311
SOX10 HMG 195 / 311
TFAP2C AP-2 152 / 311
TGIF1 Homeobox 229 / 311

All CRCs of SKMEL30
Download
CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
Download

TF name Frequency of TFs TF family Ensembl ID
RARA 280 / 311 THR-like ENSG00000131759
TGIF1 229 / 311 Homeobox ENSG00000177426
SOX10 195 / 311 HMG ENSG00000100146
RREB1 191 / 311 zf-C2H2 ENSG00000124782
POU3F1 188 / 311 Pou ENSG00000185668
RUNX3 180 / 311 Runt ENSG00000020633
TFAP2C 152 / 311 AP-2 ENSG00000087510
FOXD3 152 / 311 Fork_head ENSG00000187140
ETV4 150 / 311 ETS ENSG00000175832
MEF2D 150 / 311 SRF ENSG00000116604
TBX2 141 / 311 T-box ENSG00000121068
SMAD3 136 / 311 MH1 ENSG00000166949
NR4A2 116 / 311 NGFIB-like ENSG00000153234
PKNOX2 116 / 311 Homeobox ENSG00000165495
SOX5 110 / 311 HMG ENSG00000134532
SOX13 109 / 311 HMG ENSG00000143842
MAFB 109 / 311 TF_bZIP ENSG00000204103
ETV3 74 / 311 ETS ENSG00000117036
SNAI2 66 / 311 zf-C2H2 ENSG00000019549
TFAP2A 64 / 311 AP-2 ENSG00000137203
HES1 59 / 311 bHLH ENSG00000114315
FOXD2 56 / 311 Fork_head ENSG00000186564
ETV5 47 / 311 ETS ENSG00000244405
JUNB 46 / 311 TF_bZIP ENSG00000171223
BHLHE40 45 / 311 bHLH ENSG00000134107
IRF4 44 / 311 IRF ENSG00000137265
MITF 31 / 311 bHLH ENSG00000187098
MEF2C 25 / 311 SRF ENSG00000081189
SREBF1 21 / 311 bHLH ENSG00000072310
ARID5B 18 / 311 ARID ENSG00000150347
MNT 11 / 311 bHLH ENSG00000070444

Indegree and outdegree of TFs
Download

TF name Indegree Outdegree Node connections
JUNB 27 47 74
SMAD3 29 55 84
TBX2 32 44 76
BHLHE40 28 45 73
MITF 32 38 70
MAFB 26 55 81
SOX5 29 50 79
RARA 31 56 87
TFAP2A 23 56 79
TFAP2C 28 55 83
SOX13 25 55 80
MNT 29 28 57
RREB1 27 56 83
ARID5B 28 31 59
POU3F1 30 54 84
NR4A2 26 56 82
FOXD2 26 48 74
FOXD3 29 53 82
SNAI2 31 40 71
PKNOX2 29 49 78
ETV3 27 38 65
ETV5 32 35 67
ETV4 29 53 82
IRF4 24 43 67
MEF2C 23 47 70
RUNX3 30 56 86
SREBF1 22 54 76
MEF2D 28 44 72
HES1 27 39 66
SOX10 32 54 86
TGIF1 30 54 84

Expression of TFs in all CRCs