Cancer CRCdb

TF information

TF name:	MEF2C
TF family:	SRF
Ensembl gene ID:	ENSG00000081189
Ensembl protein ID:	ENSP00000422390, ENSP00000389610, ENSP00000489865, ENSP00000486554, ENSP00000487430, ENSP00000490473, ENSP00000426465, ENSP00000427163, ENSP00000485972, ENSP00000423826, ENSP00000487538, ENSP00000427286, ENSP00000490354, ENSP00000421925, ENSP00000424606, ENSP00000426665
Entrez gene ID:	4208

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of MEF2C in all biosamples

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Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_183	Cell line	Skin	SKMEL2	0.20512820512821
Sample_02_184	Cell line	Skin	SKMEL30	0.080385852090032

MEF2C distribution in samples’ most representative CRC

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Sample ID	Tissue type	Biosample type	Biosample name

MEF2C distribution in all CRCs

Genomic distribution of SEs associated with MEF2C

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Mutation of MEF2C

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Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of MEF2C

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr5	88047769	88047769	C	T	exonic	MEF2C	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	88027668	88027668	C	T	exonic	MEF2C	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	88178822	88178824	GAG	-	UTR5	MEF2C	unknown	ESCA\|1\|185\|0.00541
-	chr5	88018519	88018519	C	T	exonic	MEF2C	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|2\|489\|0.00409,READ\|1\|122\|0.00820
-	chr5	88047758	88047758	G	A	exonic	MEF2C	synonymous	BRCA\|1\|982\|0.00102
-	chr5	88100465	88100465	T	G	exonic	MEF2C	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	88018477	88018477	C	T	exonic	MEF2C	nonsynonymous	BLCA\|1\|396\|0.00253,LUSC\|1\|178\|0.00562
-	chr5	88057132	88057132	T	C	exonic	MEF2C	nonsynonymous	LIHC\|1\|373\|0.00268
rs567797470	chr5	88057095	88057095	C	T	exonic	MEF2C	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88056859	88056859	T	-	exonic	MEF2C	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88047822	88047822	G	A	exonic	MEF2C	synonymous	LUSC\|1\|178\|0.00562
-	chr5	88047818	88047818	C	A	exonic	MEF2C	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	88119591	88119591	-	T	exonic	MEF2C	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88100420	88100420	C	T	exonic	MEF2C	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr5	88119580	88119580	G	A	exonic	MEF2C	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr5	88057075	88057075	C	A	exonic	MEF2C	nonsynonymous	UCEC\|1\|248\|0.00403
rs796052733	chr5	88027590	88027590	G	A	exonic	MEF2C	stopgain	UCEC\|1\|248\|0.00403
-	chr5	88018626	88018626	G	A	exonic	MEF2C	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr5	88047710	88047710	C	G	exonic	MEF2C	nonsynonymous	ACC\|1\|90\|0.01111
-	chr5	88027630	88027630	G	T	exonic	MEF2C	synonymous	OV\|1\|469\|0.00213
-	chr5	88056812	88056812	T	G	exonic	MEF2C	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88047711	88047711	A	T	exonic	MEF2C	synonymous	HNSC\|1\|512\|0.00195
-	chr5	88026048	88026048	C	T	exonic	MEF2C	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr5	88018491	88018491	C	T	exonic	MEF2C	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	88025144	88025144	G	T	exonic	MEF2C	synonymous	LIHC\|1\|373\|0.00268
-	chr5	88119631	88119631	G	A	UTR5	MEF2C	unknown	ESCA\|1\|185\|0.00541
-	chr5	88047683	88047683	C	A	exonic	MEF2C	nonsynonymous	UCEC\|1\|248\|0.00403
rs17852408	chr5	88024334	88024334	G	T	exonic	MEF2C	nonsynonymous	TGCT\|1\|155\|0.00645
-	chr5	88025141	88025141	C	T	exonic	MEF2C	synonymous	SKCM\|1\|368\|0.00272
-	chr5	88027589	88027589	C	T	exonic	MEF2C	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr5	88025139	88025139	G	T	exonic	MEF2C	stopgain	SARC\|1\|247\|0.00405
-	chr5	88027605	88027605	G	T	exonic	MEF2C	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr5	88047844	88047844	T	C	exonic	MEF2C	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88027604	88027604	C	T	exonic	MEF2C	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr5	88119602	88119602	C	A	exonic	MEF2C	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	88178836	88178836	-	A	UTR5	MEF2C	unknown	SARC\|1\|247\|0.00405
-	chr5	88018473	88018473	C	G	exonic	MEF2C	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	88027692	88027692	A	G	exonic	MEF2C	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	88119701	88119701	T	G	UTR5	MEF2C	unknown	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	88057031	88057031	C	A	exonic	MEF2C	nonsynonymous	LUAD\|6\|543\|0.01105
-	chr5	88056849	88056849	T	-	exonic	MEF2C	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88100485	88100485	T	C	exonic	MEF2C	nonsynonymous	CESC\|1\|194\|0.00515
-	chr5	88018525	88018525	G	A	exonic	MEF2C	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88024383	88024383	G	C	exonic	MEF2C	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88018692	88018692	G	C	exonic	MEF2C	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88027717	88027717	C	T	exonic	MEF2C	synonymous	HNSC\|1\|512\|0.00195
-	chr5	88027676	88027676	A	G	exonic	MEF2C	nonsynonymous	PRAD\|1\|499\|0.00200
rs186648089	chr5	88057041	88057041	G	A	exonic	MEF2C	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88025096	88025096	A	G	exonic	MEF2C	synonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
-	chr5	88018645	88018645	C	A	exonic	MEF2C	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88056820	88056820	C	T	exonic	MEF2C	synonymous	BRCA\|1\|982\|0.00102
-	chr5	88119587	88119587	G	C	exonic	MEF2C	nonsynonymous	LUSC\|1\|178\|0.00562
rs587783747	chr5	88047698	88047698	G	A	exonic	MEF2C	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88047700	88047700	T	C	exonic	MEF2C	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr5	88057050	88057050	C	T	exonic	MEF2C	synonymous	ESCA\|2\|185\|0.01081
-	chr5	88025035	88025035	C	T	exonic	MEF2C	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	88018742	88018742	T	C	exonic	MEF2C	synonymous	HNSC\|1\|512\|0.00195
-	chr5	88056872	88056872	C	T	exonic	MEF2C	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88057136	88057136	T	A	exonic	MEF2C	stopgain	HNSC\|1\|512\|0.00195
-	chr5	88047694	88047694	G	A	exonic	MEF2C	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr5	88018447	88018447	G	A	exonic	MEF2C	stopgain	BRCA\|4\|982\|0.00407
-	chr5	88018719	88018719	G	C	exonic	MEF2C	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	88018583	88018583	A	T	exonic	MEF2C	synonymous	ESCA\|1\|185\|0.00541
-	chr5	88018673	88018673	G	C	exonic	MEF2C	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr5	88027620	88027620	A	C	exonic	MEF2C	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr5	88100564	88100564	C	A	exonic	MEF2C	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr5	88018629	88018629	G	C	exonic	MEF2C	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr5	88057117	88057117	C	A	exonic	MEF2C	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	88018598	88018598	C	A	exonic	MEF2C	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	88018705	88018705	G	T	exonic	MEF2C	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr5	88047695	88047695	G	A	exonic	MEF2C	nonsynonymous	HNSC\|1\|512\|0.00195
rs780541747	chr5	88056904	88056904	G	A	exonic	MEF2C	synonymous	HNSC\|1\|512\|0.00195
-	chr5	88018700	88018700	G	A	exonic	MEF2C	synonymous	SKCM\|1\|368\|0.00272
-	chr5	88119603	88119603	C	A	exonic	MEF2C	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	88047715	88047715	G	A	exonic	MEF2C	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr5	88100446	88100446	T	A	exonic	MEF2C	nonsynonymous	ACC\|1\|90\|0.01111
-	chr5	88056848	88056848	A	T	exonic	MEF2C	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,HNSC\|2\|512\|0.00391
-	chr5	88100452	88100452	T	A	exonic	MEF2C	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr5	88056823	88056823	G	A	exonic	MEF2C	synonymous	SKCM\|1\|368\|0.00272
rs780952466	chr5	88100421	88100421	G	A	exonic	MEF2C	synonymous	ESCA\|1\|185\|0.00541,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	88057087	88057087	G	A	exonic	MEF2C	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	88178836	88178836	G	-	UTR5	MEF2C	unknown	SARC\|1\|247\|0.00405
-	chr5	88018519	88018519	C	A	exonic	MEF2C	stopgain	UCEC\|1\|248\|0.00403
-	chr5	88018643	88018643	G	A	exonic	MEF2C	synonymous	SKCM\|1\|368\|0.00272
-	chr5	88027697	88027697	C	T	exonic	MEF2C	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88018658	88018658	A	G	exonic	MEF2C	synonymous	UCEC\|1\|248\|0.00403
-	chr5	88018473	88018473	C	T	exonic	MEF2C	nonsynonymous	SKCM\|1\|368\|0.00272
rs777918857	chr5	88047697	88047697	C	T	exonic	MEF2C	nonsynonymous	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409
rs796052736	chr5	88056848	88056848	-	T	exonic	MEF2C	frameshift	LIHC\|1\|373\|0.00268
-	chr5	88100464	88100464	G	A	exonic	MEF2C	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	88027589	88027589	C	A	exonic	MEF2C	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr5	88100596	88100596	A	C	exonic	MEF2C	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr5	88047801	88047801	A	C	exonic	MEF2C	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	88047672	88047672	A	T	splicing	MEF2C	splicing	HNSC\|2\|512\|0.00391
rs768570497	chr5	88018596	88018596	G	A	exonic	MEF2C	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	88027647	88027647	G	A	exonic	MEF2C	stopgain	SKCM\|1\|368\|0.00272
-	chr5	88100458	88100458	T	C	exonic	MEF2C	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	88024382	88024382	T	G	exonic	MEF2C	nonsynonymous	BRCA\|1\|982\|0.00102
rs756839313	chr5	88018547	88018547	G	A	exonic	MEF2C	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	88056893	88056893	G	A	exonic	MEF2C	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr5	88047813	88047813	G	C	exonic	MEF2C	synonymous	THCA\|1\|504\|0.00198
-	chr5	88119587	88119587	G	T	exonic	MEF2C	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr5	88056840	88056840	C	T	exonic	MEF2C	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr5	88119602	88119602	C	T	exonic	MEF2C	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr5	88018554	88018554	G	A	exonic	MEF2C	nonsynonymous	SKCM\|1\|368\|0.00272,UCEC\|1\|248\|0.00403,UCS\|1\|57\|0.01754
-	chr5	88018549	88018549	C	A	exonic	MEF2C	nonsynonymous	OV\|1\|469\|0.00213
-	chr5	88178941	88178941	C	T	UTR5	MEF2C	unknown	ESCA\|1\|185\|0.00541
-	chr5	88057031	88057031	C	T	exonic	MEF2C	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	88047821	88047821	G	T	exonic	MEF2C	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	88027681	88027681	C	T	exonic	MEF2C	synonymous	ESCA\|1\|185\|0.00541
-	chr5	88025083	88025083	G	T	exonic	MEF2C	nonsynonymous	LUAD\|1\|543\|0.00184

Disease information of MEF2C

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TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
MEF2C	Autistic Disorder	F03	Mental or Behavioral Dysfunction	CTD_human
MEF2C	Body Rocking	F03	Individual Behavior	CTD_human
MEF2C	Cerebrovascular Disorders	C10;C14	Disease or Syndrome	GENOMICS_ENGLAND
MEF2C	Epilepsy	C10	Disease or Syndrome	CTD_human
MEF2C	Head Banging	F03	Mental or Behavioral Dysfunction	CTD_human
MEF2C	Profound Mental Retardation	C10;C23;F01;F03	Mental or Behavioral Dysfunction	CTD_human
MEF2C	Mental Retardation, Psychosocial	C10;C23;F01;F03	Mental or Behavioral Dysfunction	CTD_human
MEF2C	Status Epilepticus	C10;C23	Disease or Syndrome	CTD_human
MEF2C	Stereotypic Movement Disorder	F03	Mental or Behavioral Dysfunction	CTD_human
MEF2C	Epilepsy, Cryptogenic	C10	Disease or Syndrome	CTD_human
MEF2C	Aura	C10	Finding	CTD_human
MEF2C	Petit mal status	C10;C23	Disease or Syndrome	CTD_human
MEF2C	Grand Mal Status Epilepticus	C10;C23	Disease or Syndrome	CTD_human
MEF2C	Complex Partial Status Epilepticus	C10;C23	Disease or Syndrome	CTD_human
MEF2C	Epileptic encephalopathy		Disease or Syndrome	GENOMICS_ENGLAND
MEF2C	Awakening Epilepsy	C10	Disease or Syndrome	CTD_human
MEF2C	Status Epilepticus, Subclinical	C10;C23	Disease or Syndrome	CTD_human
MEF2C	Non-Convulsive Status Epilepticus	C10;C23	Disease or Syndrome	CTD_human
MEF2C	Simple Partial Status Epilepticus	C10;C23	Disease or Syndrome	CTD_human
MEF2C	Mental deficiency	C10;C23;F01;F03	Mental or Behavioral Dysfunction	CTD_human
MEF2C	Autism Spectrum Disorders	F03	Mental or Behavioral Dysfunction	CTD_human
MEF2C	MENTAL RETARDATION, AUTOSOMAL DOMINANT 20		Disease or Syndrome	CTD_human
MEF2C	Intellectual Disability	C10;C23;F01;F03	Mental or Behavioral Dysfunction	CTD_human;GENOMICS_ENGLAND
MEF2C	CHROMOSOME 5q14.3 DELETION SYNDROME, PROXIMAL		Disease or Syndrome	CTD_human
MEF2C	5q14.3 microdeletion syndrome		Disease or Syndrome	ORPHANET

Pathway associated with MEF2C

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pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0000393	CDO in myogenesis	reactome	29	200
pathway0000430	Circadian Clock	reactome	49	389
pathway0000715	ERK/MAPK targets	reactome	17	72
pathway0001517	Notch	netpath	76	661
pathway0001560	Oxidative stress response	panther	23	125
pathway0001572	p38 MAPK pathway	panther	31	137
pathway0001849	Regulation of nuclear SMAD2/3 signaling	pid	82	1072
pathway0001857	Regulation of retinoblastoma protein	pid	67	718
pathway0002044	Signaling mediated by p38-alpha and p38-beta	pid	35	174
pathway0002299	Transcriptional activation of mitochondrial biogenesis	reactome	43	230
pathway0002340	Trk receptor signaling mediated by the MAPK pathway	pid	34	175
pathway0002725	Hs_Endochondral_Ossification_WP474_87977	wikipathways	43	117
pathway0002768	Hs_Heart_Development_WP1591_90186	wikipathways	28	78
pathway0002799	Hs_Oxidation_by_Cytochrome_P450_WP43_84102	wikipathways	14	14

Go term information of MEF2C

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GO_term_name	GO_term_type	TF_name
GO_CARDIAC_CHAMBER_DEVELOPMENT	BP	MEF2C
GO_CARDIAC_MUSCLE_ADAPTATION	BP	MEF2C
GO_NEUROLOGICAL_SYSTEM_PROCESS	BP	MEF2C
GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING	BP	MEF2C
GO_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT	BP	MEF2C
GO_MUSCLE_TISSUE_DEVELOPMENT	BP	MEF2C
GO_B_CELL_HOMEOSTASIS	BP	MEF2C
GO_SINGLE_ORGANISM_BEHAVIOR	BP	MEF2C
GO_POSITIVE_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT	BP	MEF2C
GO_CARTILAGE_DEVELOPMENT	BP	MEF2C
GO_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT	BP	MEF2C
GO_POSITIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS	BP	MEF2C
GO_REGULATION_OF_PHOSPHATASE_ACTIVITY	BP	MEF2C
GO_REGULATION_OF_SKELETAL_MUSCLE_CELL_DIFFERENTIATION	BP	MEF2C
GO_CELLULAR_RESPONSE_TO_LIPID	BP	MEF2C
GO_REGULATION_OF_DEVELOPMENTAL_GROWTH	BP	MEF2C
GO_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC	BP	MEF2C
GO_RESPONSE_TO_FLUID_SHEAR_STRESS	BP	MEF2C
GO_POSITIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION	BP	MEF2C
GO_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE	BP	MEF2C
GO_SMOOTH_MUSCLE_CELL_DIFFERENTIATION	BP	MEF2C
GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS	BP	MEF2C
GO_REGULATION_OF_PROTEIN_HOMODIMERIZATION_ACTIVITY	BP	MEF2C
GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION	BP	MEF2C
GO_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS	BP	MEF2C
GO_CELLULAR_RESPONSE_TO_FLUID_SHEAR_STRESS	BP	MEF2C
GO_REGULATION_OF_MYELOID_CELL_APOPTOTIC_PROCESS	BP	MEF2C
GO_LYMPHOCYTE_HOMEOSTASIS	BP	MEF2C
GO_REGULATION_OF_ALPHA_AMINO_3_HYDROXY_5_METHYL_4_ISOXAZOLE_PROPIONATE_SELECTIVE_GLUTAMATE_RECEPTOR_ACTIVITY	BP	MEF2C
GO_VENTRICULAR_CARDIAC_MUSCLE_CELL_DIFFERENTIATION	BP	MEF2C
GO_POSITIVE_REGULATION_OF_HEART_GROWTH	BP	MEF2C
GO_B_CELL_PROLIFERATION	BP	MEF2C
GO_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION	BP	MEF2C
GO_IMMUNE_SYSTEM_DEVELOPMENT	BP	MEF2C
GO_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS	BP	MEF2C
GO_POSITIVE_REGULATION_OF_BEHAVIOR	BP	MEF2C
GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION	BP	MEF2C
GO_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION	BP	MEF2C
GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION	BP	MEF2C
GO_CARTILAGE_MORPHOGENESIS	BP	MEF2C
GO_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT	BP	MEF2C
GO_SPECIFICATION_OF_ORGAN_IDENTITY	BP	MEF2C
GO_EXCITATORY_POSTSYNAPTIC_POTENTIAL	BP	MEF2C
GO_POSITIVE_REGULATION_OF_CELL_PROLIFERATION	BP	MEF2C
GO_REPLACEMENT_OSSIFICATION	BP	MEF2C
GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS	BP	MEF2C
GO_EMBRYONIC_VISCEROCRANIUM_MORPHOGENESIS	BP	MEF2C
GO_PIGMENTATION	BP	MEF2C
GO_ORGAN_FORMATION	BP	MEF2C
GO_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION	BP	MEF2C
GO_REGULATION_OF_MYOBLAST_DIFFERENTIATION	BP	MEF2C
GO_REGULATION_OF_HEMOPOIESIS	BP	MEF2C
GO_REGULATION_OF_BEHAVIOR	BP	MEF2C
GO_LEUKOCYTE_PROLIFERATION	BP	MEF2C
GO_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT	BP	MEF2C
GO_CELLULAR_RESPONSE_TO_TOXIC_SUBSTANCE	BP	MEF2C
GO_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL	BP	MEF2C
GO_REGULATION_OF_ORGAN_GROWTH	BP	MEF2C
GO_POSITIVE_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT	BP	MEF2C
GO_PLATELET_MORPHOGENESIS	BP	MEF2C
GO_REGULATION_OF_MEGAKARYOCYTE_DIFFERENTIATION	BP	MEF2C
GO_CHONDROCYTE_DIFFERENTIATION	BP	MEF2C
GO_RENAL_TUBULE_DEVELOPMENT	BP	MEF2C
GO_CARDIAC_VENTRICLE_MORPHOGENESIS	BP	MEF2C
GO_REGULATION_OF_SYNAPSE_ORGANIZATION	BP	MEF2C
GO_MUSCLE_ADAPTATION	BP	MEF2C
GO_REGULATION_OF_NEURON_APOPTOTIC_PROCESS	BP	MEF2C
GO_CARDIAC_MUSCLE_CELL_DIFFERENTIATION	BP	MEF2C
GO_REGULATION_OF_N_METHYL_D_ASPARTATE_SELECTIVE_GLUTAMATE_RECEPTOR_ACTIVITY	BP	MEF2C
GO_GLOMERULUS_DEVELOPMENT	BP	MEF2C
GO_POSITIVE_REGULATION_OF_CELL_ACTIVATION	BP	MEF2C
GO_PIGMENT_CELL_DIFFERENTIATION	BP	MEF2C
GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT	BP	MEF2C
GO_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT	BP	MEF2C
GO_HEART_FORMATION	BP	MEF2C
GO_CARDIAC_VENTRICLE_DEVELOPMENT	BP	MEF2C
GO_NEURON_MIGRATION	BP	MEF2C
GO_BLOOD_VESSEL_REMODELING	BP	MEF2C
GO_TISSUE_REMODELING	BP	MEF2C
GO_REGULATION_OF_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION	BP	MEF2C
GO_DEVELOPMENTAL_PIGMENTATION	BP	MEF2C
GO_CELLULAR_RESPONSE_TO_ANTIBIOTIC	BP	MEF2C
GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING	BP	MEF2C
GO_CELL_FATE_DETERMINATION	BP	MEF2C
GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION	BP	MEF2C
GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION	BP	MEF2C
GO_CELLULAR_RESPONSE_TO_CALCIUM_ION	BP	MEF2C
GO_CARDIOCYTE_DIFFERENTIATION	BP	MEF2C
GO_RESPONSE_TO_GROWTH_FACTOR	BP	MEF2C
GO_POSITIVE_REGULATION_OF_MYOBLAST_DIFFERENTIATION	BP	MEF2C
GO_MUSCLE_CELL_FATE_COMMITMENT	BP	MEF2C
GO_REGULATION_OF_B_CELL_PROLIFERATION	BP	MEF2C
GO_HEART_VALVE_DEVELOPMENT	BP	MEF2C
GO_RESPONSE_TO_PARATHYROID_HORMONE	BP	MEF2C
GO_MUSCLE_HYPERTROPHY	BP	MEF2C
GO_MESENCHYME_DEVELOPMENT	BP	MEF2C
GO_POSITIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT	BP	MEF2C
GO_NEUROEPITHELIAL_CELL_DIFFERENTIATION	BP	MEF2C
GO_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION	BP	MEF2C
GO_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT	BP	MEF2C
GO_TUBE_MORPHOGENESIS	BP	MEF2C
GO_REGULATION_OF_HEART_GROWTH	BP	MEF2C
GO_REGULATION_OF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY	BP	MEF2C
GO_OUTFLOW_TRACT_MORPHOGENESIS	BP	MEF2C
GO_NEGATIVE_REGULATION_OF_OSSIFICATION	BP	MEF2C
GO_SKELETAL_MUSCLE_CELL_DIFFERENTIATION	BP	MEF2C
GO_RESPONSE_TO_ANTIBIOTIC	BP	MEF2C
GO_CARDIAC_CHAMBER_FORMATION	BP	MEF2C
GO_ENDOCHONDRAL_BONE_MORPHOGENESIS	BP	MEF2C
GO_MELANOCYTE_DIFFERENTIATION	BP	MEF2C
GO_STRIATED_MUSCLE_ADAPTATION	BP	MEF2C
GO_POSITIVE_REGULATION_OF_DEPHOSPHORYLATION	BP	MEF2C
GO_POSITIVE_REGULATION_OF_ORGAN_GROWTH	BP	MEF2C
GO_EMBRYONIC_HEART_TUBE_MORPHOGENESIS	BP	MEF2C
GO_POSITIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION	BP	MEF2C
GO_POSITIVE_REGULATION_OF_PHOSPHATASE_ACTIVITY	BP	MEF2C
GO_MONOCYTE_DIFFERENTIATION	BP	MEF2C
GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION	BP	MEF2C
GO_LEUKOCYTE_HOMEOSTASIS	BP	MEF2C
GO_EMBRYONIC_CRANIAL_SKELETON_MORPHOGENESIS	BP	MEF2C
GO_POSITIVE_REGULATION_OF_OSSIFICATION	BP	MEF2C
GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_BINDING	MF	MEF2C
GO_ENHANCER_BINDING	MF	MEF2C
GO_MIRNA_BINDING	MF	MEF2C
GO_HISTONE_DEACETYLASE_BINDING	MF	MEF2C
GO_HMG_BOX_DOMAIN_BINDING	MF	MEF2C
GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING	MF	MEF2C
GO_ACTIVATING_TRANSCRIPTION_FACTOR_BINDING	MF	MEF2C
GO_CHROMATIN_BINDING	MF	MEF2C
GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC	MF	MEF2C
GO_CORE_PROMOTER_PROXIMAL_REGION_DNA_BINDING	MF	MEF2C

Survival analysis of MEF2C

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of MEF2C

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)