Cancer CRCdb

TF information

TF name:	RARA
TF family:	THR-like
Ensembl gene ID:	ENSG00000131759
Ensembl protein ID:	ENSP00000377649, ENSP00000377648, ENSP00000377643, ENSP00000462514, ENSP00000254066, ENSP00000389993
Entrez gene ID:	5914

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of RARA in all biosamples

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Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_01_001	Cell line	Prostate	22Rv1	0.15980629539952
Sample_02_078	Primary cell	Neuroblastoma	low-MYCN-Neuroblastoma-patient-cells	0.75
Sample_02_079	Cell line	Mammary Gland	T-47D_1	0.66666666666667
Sample_02_080	Cell line	Lung	Calu-3	0.72727272727273
Sample_02_095	Cell line	Mammary Gland	MDA-MB-468	0.81439688715953
Sample_02_096	Cell line	Mammary Gland	ZR-75-1_1	1
Sample_02_115	Cell line	Mammary Gland	MCF-7	1
Sample_02_161	Cell line	Brain	U87	1
Sample_02_166	Cell line	Mammary Gland	HCC1954_Parental	0.768
Sample_02_180	Cell line	Human melanoma	CJM	0.484375
Sample_02_181	Cell line	Human melanoma	COLO679	0.6032
Sample_02_183	Cell line	Skin	SKMEL2	0.46153846153846
Sample_02_184	Cell line	Skin	SKMEL30	0.90032154340836
Sample_02_205	Tissue	Stomach	Gastric_Primary_Sample_T	0.17037037037037
Sample_02_220	Cell line	Brain	BE2C_1	0.30769230769231
Sample_02_254	Cell line	Neuroblastoma	IMR5-75	0.97058823529412
Sample_02_267	Cell line	Kidney	786-O	1
Sample_02_268	Cell line	Kidney	A-498	0.90899021598671
Sample_02_280	Cell line	Mammary Gland	SUM159_DMSO_24h	1
Sample_02_296	Cell line	Neuroblastoma	CLB-BER-Lud	1
Sample_02_298	Cell line	Neuroblastoma	CLB-GA	0.86301369863014
Sample_02_299	Cell line	Neuroblastoma	CLB-MA	0.99520383693046
Sample_02_302	Cell line	Neuroblastoma	IMR32	0.96428571428571
Sample_02_303	Cell line	Neuroblastoma	LAN1	0.88571428571429
Sample_02_304	Cell line	Neuroblastoma	N206	1
Sample_02_307	Cell line	Neuroblastoma	SJNB12	0.88732394366197
Sample_02_308	Cell line	Neuroblastoma	SJNB1	0.890625
Sample_02_309	Cell line	Neuroblastoma	SJNB6	0.99526066350711
Sample_02_310	Cell line	Neuroblastoma	SJNB8	0.97444298820446
Sample_02_311	Cell line	Neuroblastoma	SK-N-AS	0.76623376623377
Sample_02_312	Cell line	Neuroblastoma	SK-N-BE_2-C	0.82978723404255
Sample_02_313	Cell line	Neuroblastoma	SK-N-DZ	0.996138996139
Sample_02_314	Cell line	Neuroblastoma	SK-N-FI	0.99382716049383
Sample_02_316	Cell line	Neuroblastoma	CHP212	0.96153846153846
Sample_02_317	Cell line	Neuroblastoma	GICAN	0.72972972972973
Sample_02_318	Cell line	Neuroblastoma	NB69	0.9921875
Sample_02_319	Cell line	Neuroblastoma	NB-EBc1	0.71098265895954
Sample_02_338	Cell line	Neuroblastoma	BE2	0.32352941176471
Sample_02_354	Cell line	Colon	Colo205	1
Sample_02_356	Cell line	Colon	Sw480	1
Sample_02_358	Cell line	Colon	LS180	0.79225908372828
Sample_02_359	Cell line	Colon	Colo741	0.8855421686747
Sample_02_361	Cell line	Colon	HT29_DMSO	0.85840707964602
Sample_02_394	Cell line	Mammary Gland	T-47D_2	1
Sample_02_395	Cell line	Mammary Gland	BT-549	1
Sample_02_403	Cell line	Mammary Gland	T-47D_untreat	0.69318181818182
Sample_02_404	Cell line	Mammary Gland	ZR-75-1_2	0.9136690647482
Sample_02_406	Cell line	Mammary Gland	ZR-75-30_parental	0.65217391304348
Sample_02_430	Cell line	Kidney	12364284	0.64285714285714

RARA distribution in samples’ most representative CRC

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Sample ID	Tissue type	Biosample type	Biosample name
Sample_02_078	Neuroblastoma	Primary cell	low-MYCN-Neuroblastoma-patient-cells
Sample_02_080	Lung	Cell line	Calu-3
Sample_02_095	Mammary Gland	Cell line	MDA-MB-468
Sample_02_096	Mammary Gland	Cell line	ZR-75-1_1
Sample_02_115	Mammary Gland	Cell line	MCF-7
Sample_02_161	Brain	Cell line	U87
Sample_02_166	Mammary Gland	Cell line	HCC1954_Parental
Sample_02_180	Human melanoma	Cell line	CJM
Sample_02_181	Human melanoma	Cell line	COLO679
Sample_02_184	Skin	Cell line	SKMEL30
Sample_02_220	Brain	Cell line	BE2C_1
Sample_02_254	Neuroblastoma	Cell line	IMR5-75
Sample_02_267	Kidney	Cell line	786-O
Sample_02_268	Kidney	Cell line	A-498
Sample_02_280	Mammary Gland	Cell line	SUM159_DMSO_24h
Sample_02_296	Neuroblastoma	Cell line	CLB-BER-Lud
Sample_02_298	Neuroblastoma	Cell line	CLB-GA
Sample_02_299	Neuroblastoma	Cell line	CLB-MA
Sample_02_302	Neuroblastoma	Cell line	IMR32
Sample_02_303	Neuroblastoma	Cell line	LAN1
Sample_02_304	Neuroblastoma	Cell line	N206
Sample_02_307	Neuroblastoma	Cell line	SJNB12
Sample_02_308	Neuroblastoma	Cell line	SJNB1
Sample_02_309	Neuroblastoma	Cell line	SJNB6
Sample_02_310	Neuroblastoma	Cell line	SJNB8
Sample_02_311	Neuroblastoma	Cell line	SK-N-AS
Sample_02_312	Neuroblastoma	Cell line	SK-N-BE_2-C
Sample_02_313	Neuroblastoma	Cell line	SK-N-DZ
Sample_02_314	Neuroblastoma	Cell line	SK-N-FI
Sample_02_316	Neuroblastoma	Cell line	CHP212
Sample_02_317	Neuroblastoma	Cell line	GICAN
Sample_02_318	Neuroblastoma	Cell line	NB69
Sample_02_319	Neuroblastoma	Cell line	NB-EBc1
Sample_02_338	Neuroblastoma	Cell line	BE2
Sample_02_354	Colon	Cell line	Colo205
Sample_02_356	Colon	Cell line	Sw480
Sample_02_358	Colon	Cell line	LS180
Sample_02_359	Colon	Cell line	Colo741
Sample_02_361	Colon	Cell line	HT29_DMSO
Sample_02_394	Mammary Gland	Cell line	T-47D_2
Sample_02_395	Mammary Gland	Cell line	BT-549
Sample_02_403	Mammary Gland	Cell line	T-47D_untreat
Sample_02_404	Mammary Gland	Cell line	ZR-75-1_2
Sample_02_406	Mammary Gland	Cell line	ZR-75-30_parental
Sample_02_430	Kidney	Cell line	12364284

RARA distribution in all CRCs

Genomic distribution of SEs associated with RARA

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Mutation of RARA

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Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of RARA

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr17	38487575	38487575	C	G	exonic	RARA	synonymous	LUAD\|1\|543\|0.00184
-	chr17	38511645	38511645	T	C	exonic	RARA	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs200393055	chr17	38508238	38508238	G	A	exonic	RARA	synonymous	ESCA\|1\|185\|0.00541
rs376736940	chr17	38487581	38487581	G	A	exonic	RARA	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr17	38498963	38498963	G	C	exonic	RARA	nonsynonymous	BLCA\|2\|396\|0.00505
-	chr17	38510653	38510653	G	A	exonic	RARA	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr17	38498977	38498977	G	-	exonic	RARA	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	38506137	38506137	C	T	exonic	RARA	synonymous	LUAD\|1\|543\|0.00184
-	chr17	38508264	38508287	TGCGCAAAGCGCACCAGGAAACCT	-	exonic	RARA	nonframeshift	ACC\|1\|90\|0.01111
-	chr17	38508601	38508601	C	A	exonic	RARA	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr17	38508183	38508184	AG	-	exonic	RARA	frameshift	HNSC\|1\|512\|0.00195
-	chr17	38504711	38504711	T	A	exonic	RARA	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr17	38510626	38510626	C	T	exonic	RARA	nonsynonymous	BLCA\|2\|396\|0.00505
-	chr17	38499089	38499089	C	T	exonic	RARA	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr17	38508725	38508725	-	A	exonic	RARA	frameshift	THCA\|1\|504\|0.00198
rs766689873	chr17	38512394	38512394	T	G	exonic	RARA	synonymous	TGCT\|1\|155\|0.00645
-	chr17	38511548	38511548	A	G	exonic	RARA	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr17	38508322	38508322	G	A	exonic	RARA	synonymous	HNSC\|1\|512\|0.00195
rs138717943	chr17	38511541	38511541	C	T	exonic	RARA	nonsynonymous	SARC\|1\|247\|0.00405
-	chr17	38512373	38512373	G	C	exonic	RARA	synonymous	SKCM\|1\|368\|0.00272
-	chr17	38508601	38508601	C	T	exonic	RARA	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr17	38506177	38506177	T	C	exonic	RARA	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr17	38487504	38487504	G	T	exonic	RARA	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr17	38506062	38506062	G	A	exonic	RARA	synonymous	BRCA\|1\|982\|0.00102
-	chr17	38510648	38510648	G	T	exonic	RARA	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr17	38487555	38487555	C	T	exonic	RARA	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	38512460	38512460	G	T	exonic	RARA	synonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
-	chr17	38510642	38510642	A	G	exonic	RARA	nonsynonymous	BLCA\|2\|396\|0.00505
-	chr17	38508717	38508717	C	A	exonic	RARA	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	38498981	38498981	G	A	exonic	RARA	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	38508189	38508189	A	C	exonic	RARA	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	38487554	38487554	C	-	exonic	RARA	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr17	38510698	38510698	C	T	exonic	RARA	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	38510721	38510721	G	C	exonic	RARA	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr17	38510598	38510598	G	A	exonic	RARA	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr17	38508596	38508596	A	G	exonic	RARA	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr17	38510615	38510615	T	C	exonic	RARA	nonsynonymous	TGCT\|1\|155\|0.00645
-	chr17	38508718	38508718	G	A	exonic	RARA	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	38487528	38487528	C	T	exonic	RARA	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr17	38508320	38508320	A	G	exonic	RARA	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
rs563927918	chr17	38487497	38487497	G	A	exonic	RARA	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	38508302	38508302	C	A	exonic	RARA	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr17	38511642	38511642	G	C	exonic	RARA	nonsynonymous	OV\|1\|469\|0.00213
-	chr17	38510748	38510748	C	T	exonic	RARA	synonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr17	38508718	38508718	G	T	exonic	RARA	nonsynonymous	LUAD\|1\|543\|0.00184
rs780324094	chr17	38510742	38510742	C	T	exonic	RARA	synonymous	LUSC\|1\|178\|0.00562
-	chr17	38487490	38487490	C	T	exonic	RARA	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr17	38510560	38510560	C	T	exonic	RARA	nonsynonymous	CHOL\|1\|35\|0.02857,COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs756853250	chr17	38508726	38508726	C	T	exonic	RARA	synonymous	BRCA\|1\|982\|0.00102
rs754292583	chr17	38508267	38508267	G	A	exonic	RARA	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr17	38510602	38510602	T	A	exonic	RARA	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr17	38508701	38508701	C	T	exonic	RARA	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	38508593	38508593	C	T	exonic	RARA	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	38510603	38510603	T	C	exonic	RARA	nonsynonymous	BRCA\|1\|982\|0.00102,LUAD\|1\|543\|0.00184
-	chr17	38512358	38512358	G	A	exonic	RARA	synonymous	HNSC\|1\|512\|0.00195
-	chr17	38506145	38506145	A	G	exonic	RARA	nonsynonymous	KIPAN\|2\|799\|0.00250,KIRC\|2\|451\|0.00443
-	chr17	38499007	38499007	G	T	exonic	RARA	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs779768382	chr17	38499018	38499018	A	G	exonic	RARA	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr17	38506076	38506076	C	T	exonic	RARA	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|1\|248\|0.00403
-	chr17	38508633	38508633	G	T	exonic	RARA	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr17	38511518	38511518	G	A	exonic	RARA	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	38512341	38512341	G	A	exonic	RARA	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr17	38508602	38508602	G	C	exonic	RARA	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253

Disease information of RARA

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TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
RARA	Malignant neoplasm of breast	C04;C17	Neoplastic Process	CTD_human
RARA	Phyllodes Tumor	C04	Neoplastic Process	CTD_human
RARA	Acute Promyelocytic Leukemia	C04	Neoplastic Process	CTD_human;ORPHANET
RARA	Schizophrenia	F03	Mental or Behavioral Dysfunction	PSYGENET
RARA	Neoplasms, Second Primary	C04	Neoplastic Process	CTD_human
RARA	Neoplasms, Therapy-Associated	C04	Neoplastic Process	CTD_human
RARA	Sciatic Neuropathy	C10	Disease or Syndrome	CTD_human
RARA	Lesion of Sciatic Nerve	C10	Disease or Syndrome	CTD_human
RARA	Fibroadenoma	C04	Neoplastic Process	CTD_human
RARA	Sciatic Neuritis	C10	Disease or Syndrome	CTD_human
RARA	Mood Disorders	F03	Mental or Behavioral Dysfunction	PSYGENET
RARA	Malignant Cystosarcoma Phyllodes	C04	Neoplastic Process	CTD_human
RARA	Breast Carcinoma	C04;C17	Neoplastic Process	CTD_human
RARA	Neuralgia-Neuritis, Sciatic Nerve	C10	Disease or Syndrome	CTD_human
RARA	Sciatic Nerve Palsy	C10	Disease or Syndrome	CTD_human
RARA	Treatment related secondary malignancy	C04	Neoplastic Process	CTD_human
RARA	Mammary Neoplasms, Human	C04;C17	Neoplastic Process	CTD_human
RARA	Mammary Neoplasms	C04;C17	Neoplastic Process	CTD_human
RARA	Liver carcinoma	C04;C06	Neoplastic Process	CTD_human

Pathway associated with RARA

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pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0000842	FSH	netpath	44	301
pathway0001534	Nuclear Receptor transcription pathway	reactome	51	284
pathway0001883	Retinoic acid receptors-mediated signaling	pid	30	235
pathway0001947	RXR and RAR heterodimerization with other nuclear receptor	pid	26	164
pathway0002028	Signaling by Retinoic Acid	reactome	20	78
pathway0002668	Acute myeloid leukemia	kegg	53	562
pathway0002686	Hs_Tryptophan_metabolism_WP465_85055	wikipathways	45	103

Go term information of RARA

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GO_term_name	GO_term_type	TF_name
GO_CARDIAC_CHAMBER_DEVELOPMENT	BP	RARA
GO_HEPATICOBILIARY_SYSTEM_DEVELOPMENT	BP	RARA
GO_REGULATION_OF_INTERLEUKIN_4_PRODUCTION	BP	RARA
GO_REGULATION_OF_INTERLEUKIN_5_PRODUCTION	BP	RARA
GO_MUSCLE_TISSUE_DEVELOPMENT	BP	RARA
GO_CARDIAC_SEPTUM_DEVELOPMENT	BP	RARA
GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION	BP	RARA
GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	BP	RARA
GO_OUTFLOW_TRACT_SEPTUM_MORPHOGENESIS	BP	RARA
GO_CARDIAC_CHAMBER_MORPHOGENESIS	BP	RARA
GO_POSITIVE_REGULATION_OF_BINDING	BP	RARA
GO_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE	BP	RARA
GO_STRIATED_MUSCLE_CELL_DIFFERENTIATION	BP	RARA
GO_VENTRICULAR_CARDIAC_MUSCLE_CELL_DIFFERENTIATION	BP	RARA
GO_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION	BP	RARA
GO_APOPTOTIC_CELL_CLEARANCE	BP	RARA
GO_REGULATION_OF_MYELINATION	BP	RARA
GO_KIDNEY_EPITHELIUM_DEVELOPMENT	BP	RARA
GO_CELLULAR_RESPONSE_TO_ACID_CHEMICAL	BP	RARA
GO_REGULATION_OF_T_HELPER_2_CELL_DIFFERENTIATION	BP	RARA
GO_BONE_GROWTH	BP	RARA
GO_FOREBRAIN_DEVELOPMENT	BP	RARA
GO_NEGATIVE_REGULATION_OF_TRANSLATIONAL_INITIATION	BP	RARA
GO_GLANDULAR_EPITHELIAL_CELL_DEVELOPMENT	BP	RARA
GO_REGULATION_OF_GRANULOCYTE_DIFFERENTIATION	BP	RARA
GO_POSITIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE	BP	RARA
GO_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION	BP	RARA
GO_NEGATIVE_REGULATION_OF_HEMOPOIESIS	BP	RARA
GO_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	BP	RARA
GO_NEGATIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION	BP	RARA
GO_PALLIUM_DEVELOPMENT	BP	RARA
GO_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	BP	RARA
GO_MULTICELLULAR_ORGANISM_GROWTH	BP	RARA
GO_FACE_DEVELOPMENT	BP	RARA
GO_NEGATIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT	BP	RARA
GO_ORGAN_GROWTH	BP	RARA
GO_REGULATION_OF_INTERLEUKIN_13_PRODUCTION	BP	RARA
GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS	BP	RARA
GO_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	BP	RARA
GO_TRACHEA_DEVELOPMENT	BP	RARA
GO_POSITIVE_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION	BP	RARA
GO_GROWTH	BP	RARA
GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DEVELOPMENT	BP	RARA
GO_RESPONSE_TO_LIPID	BP	RARA
GO_RESPONSE_TO_VITAMIN_A	BP	RARA
GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DIFFERENTIATION	BP	RARA
GO_MULTI_MULTICELLULAR_ORGANISM_PROCESS	BP	RARA
GO_POSITIVE_REGULATION_OF_INTERLEUKIN_4_PRODUCTION	BP	RARA
GO_TUBE_FORMATION	BP	RARA
GO_CARTILAGE_DEVELOPMENT_INVOLVED_IN_ENDOCHONDRAL_BONE_MORPHOGENESIS	BP	RARA
GO_CARDIOCYTE_DIFFERENTIATION	BP	RARA
GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS	BP	RARA
GO_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION	BP	RARA
GO_STEROID_HORMONE_MEDIATED_SIGNALING_PATHWAY	BP	RARA
GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	BP	RARA
GO_CELLULAR_RESPONSE_TO_ESTROGEN_STIMULUS	BP	RARA
GO_REGULATION_OF_TRANSLATIONAL_INITIATION	BP	RARA
GO_POSITIVE_REGULATION_OF_INTERLEUKIN_13_PRODUCTION	BP	RARA
GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	BP	RARA
GO_ENDOCHONDRAL_BONE_MORPHOGENESIS	BP	RARA
GO_CARDIAC_SEPTUM_MORPHOGENESIS	BP	RARA
GO_NEGATIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION	BP	RARA
GO_PROSTATE_GLAND_DEVELOPMENT	BP	RARA
GO_RESPONSE_TO_NUTRIENT	BP	RARA
GO_TELENCEPHALON_DEVELOPMENT	BP	RARA
GO_GROWTH_PLATE_CARTILAGE_DEVELOPMENT	BP	RARA
GO_REGULATION_OF_BINDING	BP	RARA
GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION	BP	RARA
GO_POSITIVE_REGULATION_OF_CELL_CYCLE	BP	RARA
GO_SERTOLI_CELL_DIFFERENTIATION	BP	RARA
GO_LIMBIC_SYSTEM_DEVELOPMENT	BP	RARA
GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION	BP	RARA
GO_MESONEPHROS_DEVELOPMENT	BP	RARA
GO_EPITHELIAL_CELL_FATE_COMMITMENT	BP	RARA
GO_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY	BP	RARA
GO_REGULATION_OF_CELL_PROLIFERATION	BP	RARA
GO_EMBRYONIC_CAMERA_TYPE_EYE_DEVELOPMENT	BP	RARA
GO_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION	BP	RARA
GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	BP	RARA
GO_GLANDULAR_EPITHELIAL_CELL_DIFFERENTIATION	BP	RARA
GO_RETINOIC_ACID_BINDING	MF	RARA
GO_TRANSCRIPTION_FACTOR_ACTIVITY_DIRECT_LIGAND_REGULATED_SEQUENCE_SPECIFIC_DNA_BINDING	MF	RARA
GO_PROTEIN_KINASE_A_BINDING	MF	RARA
GO_ACTININ_BINDING	MF	RARA
GO_CHROMATIN_DNA_BINDING	MF	RARA
GO_ISOPRENOID_BINDING	MF	RARA
GO_TRANSCRIPTION_FACTOR_BINDING	MF	RARA
GO_TRANSLATION_REGULATOR_ACTIVITY	MF	RARA
GO_TRANSLATION_REPRESSOR_ACTIVITY	MF	RARA
GO_TRANSLATION_REGULATOR_ACTIVITY_NUCLEIC_ACID_BINDING	MF	RARA
GO_ALPHA_ACTININ_BINDING	MF	RARA
GO_MONOCARBOXYLIC_ACID_BINDING	MF	RARA

Survival analysis of RARA

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of RARA

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)