Sample overview of CLB-BER-Lud

Sample ID: Sample_02_296
Biosample type: Cell line
Tissue type: Neuroblastoma
Biosample name: CLB-BER-Lud
Data source: NCBI GEO/SRA
GSE ID: GSE90683
Cancer type: Neuroblastoma
CRC number: 1307
TF number of all CRCs: 47
TF list of all CRCs: RARA, HOXC10, HOXD8, TEF, MEIS1, HOXC5, HOXC4, HOXC8, JUNB, KLF7, GATA3, KLF13, HOXC9, TFAP2B, JUND, MEIS2, HOXC6, RXRA, TEAD1, GLI2, EBF1, TBX2, PHOX2B, PHOX2A, TLX2, SOX9, MAZ, ISL1, GATA2, KLF16, SATB1, SOX12, SOX4, CDX1, RORA, SREBF2, ZBTB7B, ATF4, FEV, ZNF217, NR2F2, NFE2L1, ETV1, CREB1, NFIB, MAFG, SIX3

The most representative CRC of CLB-BER-Lud
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Relationship plot of CRC model
TF number of this CRC: 17
CRC socre: 712.4118
TF list of the most representative CRC
TF name TF family Frequency of TFs
EBF1 COE 428 / 1307
GATA3 zf-GATA 651 / 1307
GLI2 zf-C2H2 429 / 1307
HOXC10 Homeobox 1009 / 1307
HOXC4 Homeobox 727 / 1307
HOXC5 Homeobox 727 / 1307
HOXC8 Homeobox 687 / 1307
HOXC9 Homeobox 609 / 1307
HOXD8 Homeobox 950 / 1307
JUNB TF_bZIP 683 / 1307
KLF13 zf-C2H2 632 / 1307
KLF7 zf-C2H2 669 / 1307
MEIS1 Homeobox 748 / 1307
RARA THR-like 1307 / 1307
TEAD1 TEA 495 / 1307
TEF TF_bZIP 753 / 1307
TFAP2B AP-2 607 / 1307

All CRCs of CLB-BER-Lud
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
RARA 1307 / 1307 THR-like ENSG00000131759
HOXC10 1009 / 1307 Homeobox ENSG00000180818
HOXD8 950 / 1307 Homeobox ENSG00000175879
TEF 753 / 1307 TF_bZIP ENSG00000167074
MEIS1 748 / 1307 Homeobox ENSG00000143995
HOXC4 727 / 1307 Homeobox ENSG00000198353
HOXC5 727 / 1307 Homeobox ENSG00000172789
HOXC8 687 / 1307 Homeobox ENSG00000037965
JUNB 683 / 1307 TF_bZIP ENSG00000171223
KLF7 669 / 1307 zf-C2H2 ENSG00000118263
GATA3 651 / 1307 zf-GATA ENSG00000107485
KLF13 632 / 1307 zf-C2H2 ENSG00000169926
HOXC9 609 / 1307 Homeobox ENSG00000180806
TFAP2B 607 / 1307 AP-2 ENSG00000008196
JUND 600 / 1307 TF_bZIP ENSG00000130522
MEIS2 554 / 1307 Homeobox ENSG00000134138
HOXC6 515 / 1307 Homeobox ENSG00000197757
RXRA 502 / 1307 RXR-like ENSG00000186350
TEAD1 495 / 1307 TEA ENSG00000187079
GLI2 429 / 1307 zf-C2H2 ENSG00000074047
EBF1 428 / 1307 COE ENSG00000164330
TBX2 428 / 1307 T-box ENSG00000121068
PHOX2B 397 / 1307 Homeobox ENSG00000109132
PHOX2A 343 / 1307 Homeobox ENSG00000165462
SOX9 317 / 1307 HMG ENSG00000125398
TLX2 317 / 1307 Homeobox ENSG00000115297
MAZ 294 / 1307 zf-C2H2 ENSG00000103495
ISL1 272 / 1307 Homeobox ENSG00000016082
GATA2 202 / 1307 zf-GATA ENSG00000179348
KLF16 174 / 1307 zf-C2H2 ENSG00000129911
SATB1 163 / 1307 CUT ENSG00000182568
SOX12 159 / 1307 HMG ENSG00000177732
SOX4 136 / 1307 HMG ENSG00000124766
CDX1 133 / 1307 Homeobox ENSG00000113722
RORA 131 / 1307 THR-like ENSG00000069667
SREBF2 126 / 1307 bHLH ENSG00000198911
ZBTB7B 124 / 1307 ZBTB ENSG00000160685
ATF4 113 / 1307 TF_bZIP ENSG00000128272
FEV 104 / 1307 ETS ENSG00000163497
ZNF217 90 / 1307 zf-C2H2 ENSG00000171940
NR2F2 85 / 1307 RXR-like ENSG00000185551
NFE2L1 84 / 1307 TF_bZIP ENSG00000082641
ETV1 65 / 1307 NA NA
CREB1 59 / 1307 TF_bZIP ENSG00000118260
NFIB 48 / 1307 CTF/NFI ENSG00000147862
MAFG 9 / 1307 TF_bZIP ENSG00000197063
SIX3 8 / 1307 Homeobox ENSG00000138083

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
HOXC9 51 71 122
HOXC8 51 61 112
ZNF217 48 45 93
TFAP2B 49 70 119
CDX1 31 73 104
ISL1 52 56 108
HOXC5 51 66 117
JUND 45 75 120
MEIS1 48 74 122
TBX2 46 69 115
SOX9 39 78 117
SIX3 36 42 78
TEAD1 49 66 115
SOX4 34 76 110
MAFG 24 45 69
RARA 52 78 130
KLF7 51 65 116
PHOX2B 47 66 113
KLF16 37 67 104
SOX12 34 73 107
MEIS2 47 71 118
TEF 46 74 120
NR2F2 34 62 96
GLI2 47 63 110
KLF13 49 71 120
RORA 37 73 110
HOXC4 51 65 116
JUNB 52 62 114
HOXD8 48 72 120
ZBTB7B 37 65 102
RXRA 47 72 119
CREB1 42 57 99
FEV 35 60 95
HOXC10 51 73 124
SATB1 42 70 112
ATF4 37 66 103
PHOX2A 46 63 109
GATA2 50 58 108
GATA3 52 74 126
ETV1 40 46 86
NFIB 35 53 88
MAZ 43 74 117
TLX2 41 74 115
SREBF2 29 71 100
EBF1 42 70 112
HOXC6 51 62 113
NFE2L1 42 51 93

Expression of TFs in all CRCs