TF information

TF name: HOXC4
TF family: Homeobox
Ensembl gene ID: ENSG00000198353
Ensembl protein ID: ENSP00000305973, ENSP00000399808
Entrez gene ID: 3221
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of HOXC4 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_01_001Cell lineProstate22Rv10.031476997578692
Sample_02_069Cell lineBrainSF2680.29770992366412
Sample_02_182Cell lineHuman melanomaLOX-IMVI0.13793103448276
Sample_02_220Cell lineBrainBE2C_10.26923076923077
Sample_02_228Cell lineOesophagusKYSE5100.033550792171482
Sample_02_258OtherLungNCI-H1299_EGFP-NEO_reporter_cells_DMSO0.16666666666667
Sample_02_296Cell lineNeuroblastomaCLB-BER-Lud0.55623565416985
Sample_02_312Cell lineNeuroblastomaSK-N-BE_2-C0.75
Sample_02_338Cell lineNeuroblastomaBE20.26470588235294
Sample_02_359Cell lineColonColo7410.18373493975904
Sample_02_395Cell lineMammary GlandBT-5490.29258741258741

HOXC4 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_228OesophagusCell lineKYSE510
Sample_02_296NeuroblastomaCell lineCLB-BER-Lud
Sample_02_312NeuroblastomaCell lineSK-N-BE_2-C
Sample_02_395Mammary GlandCell lineBT-549

HOXC4 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with HOXC4
Download

Mutation of HOXC4
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of HOXC4

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr125444876954448769CAexonicHOXC4stopgain TGCT|1|155|0.00645
-chr125444871454448714GCexonicHOXC4nonsynonymous BRCA|1|982|0.00102
-chr125444770954447709GCexonicHOXC4nonsynonymous CESC|1|194|0.00515
-chr125444785754447857GAexonicHOXC4nonsynonymous BLCA|1|396|0.00253
-chr125444784154447841CAexonicHOXC4nonsynonymous LIHC|1|373|0.00268
-chr125444894154448941CTexonicHOXC4synonymous UCEC|1|248|0.00403
rs200111255chr125444866654448666CTexonicHOXC4nonsynonymous PRAD|2|499|0.00401
-chr125444799454447994GTexonicHOXC4synonymous LIHC|1|373|0.00268
-chr125444888654448886CGexonicHOXC4nonsynonymous LUAD|1|543|0.00184
-chr125444773954447739CAexonicHOXC4nonsynonymous LIHC|2|373|0.00536
-chr125444808754448087CTexonicHOXC4synonymous LIHC|1|373|0.00268
-chr125444781754447817CTexonicHOXC4synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr125444772154447721GTexonicHOXC4synonymous LUAD|1|543|0.00184
-chr125444876554448765CAexonicHOXC4nonsynonymous ACC|1|90|0.01111
-chr125444777054447770GCexonicHOXC4nonsynonymous LUSC|1|178|0.00562
rs562717137chr125444797554447975ACexonicHOXC4nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
rs767966253chr125444875554448755CAexonicHOXC4synonymous HNSC|2|512|0.00391
-chr125444807354448073G-exonicHOXC4frameshift LUAD|1|543|0.00184
-chr125444800654448006GAexonicHOXC4synonymous BLCA|1|396|0.00253
-chr125444807054448070CTexonicHOXC4nonsynonymous SKCM|2|368|0.00543
-chr125444874254448742GAexonicHOXC4nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr125444877154448771CTexonicHOXC4synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr125444780654447806CAexonicHOXC4nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr125444882054448820TAexonicHOXC4nonsynonymous HNSC|1|512|0.00195
-chr125444777854447778GAexonicHOXC4synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr125444894354448943CTexonicHOXC4nonsynonymous HNSC|1|512|0.00195
-chr125444870854448708GCexonicHOXC4nonsynonymous LUAD|1|543|0.00184
-chr125444881754448817GAexonicHOXC4nonsynonymous COAD|2|367|0.00545,COADREAD|2|489|0.00409,PRAD|1|499|0.00200
-chr125444775654447756TCexonicHOXC4nonsynonymous UCEC|1|248|0.00403
-chr125444875654448756GAexonicHOXC4nonsynonymous HNSC|1|512|0.00195
-chr125444789854447898GTexonicHOXC4nonsynonymous LUAD|1|543|0.00184
-chr125444897354448973AGexonicHOXC4nonsynonymous UCEC|1|248|0.00403
-chr125444813454448134AGexonicHOXC4nonsynonymous PAAD|1|185|0.00541
-chr125444792654447926GCexonicHOXC4nonsynonymous OV|1|469|0.00213
rs752744810chr125444895054448950GAexonicHOXC4synonymous BRCA|1|982|0.00102
-chr125444791554447915CTexonicHOXC4nonsynonymous UCEC|1|248|0.00403
-chr125444880654448806CTexonicHOXC4synonymous SKCM|2|368|0.00543
-chr125444867854448678GCexonicHOXC4nonsynonymous PRAD|1|499|0.00200
-chr125444794054447940GAexonicHOXC4synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr125444876454448764CAexonicHOXC4synonymous LUAD|1|543|0.00184
-chr125444881254448812CTexonicHOXC4synonymous SKCM|1|368|0.00272
-chr125444868954448689GCexonicHOXC4synonymous BRCA|1|982|0.00102
-chr125444803654448036GTexonicHOXC4synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr125444775954447759CAexonicHOXC4nonsynonymous ESCA|1|185|0.00541
-chr125444866754448667GAexonicHOXC4nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs776852773chr125444782254447822GAexonicHOXC4nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr125444773554447735CGexonicHOXC4nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr125444778854447788TAexonicHOXC4nonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
rs201031063chr125444788154447881CTexonicHOXC4nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr125444782154447821CTexonicHOXC4nonsynonymous CESC|1|194|0.00515
-chr125444771454447714TAexonicHOXC4nonsynonymous HNSC|1|512|0.00195
-chr125444807954448079CTexonicHOXC4nonsynonymous BLCA|1|396|0.00253
-chr125444891454448914GAexonicHOXC4synonymous PAAD|1|185|0.00541
rs75256744chr125444810654448106AGexonicHOXC4nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222

Disease information of HOXC4
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source

Pathway associated with HOXC4
pathway_ID pathway_name pathway_source gene_number edge_number

Go term information of HOXC4
GO_term_name GO_term_type TF_name
GO_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION BP HOXC4
GO_CONNECTIVE_TISSUE_DEVELOPMENT BP HOXC4
GO_HMG_BOX_DOMAIN_BINDING MF HOXC4

Survival analysis of HOXC4



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of HOXC4