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Sample overview of SF268

Sample ID: Sample_02_069
Biosample type: Cell line
Tissue type: Brain
Biosample name: SF268
Data source: NCBI GEO/SRA
GSE ID: GSE61852
Cancer type: Glioblastoma
CRC number: 131
TF number of all CRCs: 44
TF list of all CRCs: HOXA10, POU3F2, FOXG1, HOXC13, SMAD3, HOXA4, HOXA5, HOXC12, HOXC10, HOXC11, TGIF1, BHLHE40, HOXA3, HOXA7, FOSL2, HOXC9, MEIS2, EN1, HIC1, RFX2, HOXC4, MAFK, HOXA2, GBX2, DLX2, HOXA6, HOXC8, DLX1, HOXA1, NR2F2, HOXC5, ERF, TFAP2A, HOXC6, RUNX2, TEAD1, ZNF217, FOXC2, NFATC2, CREB3L1, HOXB7, HOXB8, HES7, YY1
The most representative CRC of SF268
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Relationship plot of CRC model
TF number of this CRC: 16
CRC socre: 78.6875
TF list of the most representative CRC
TF name TF family Frequency of TFs
BHLHE40 bHLH 67 / 131
FOSL2 TF_bZIP 54 / 131
FOXG1 Fork_head 113 / 131
HIC1 ZBTB 41 / 131
HOXA10 Homeobox 118 / 131
HOXA4 Homeobox 81 / 131
HOXA5 Homeobox 81 / 131
HOXC10 Homeobox 78 / 131
HOXC11 Homeobox 70 / 131
HOXC12 Homeobox 81 / 131
HOXC13 Homeobox 98 / 131
HOXC9 Homeobox 54 / 131
MEIS2 Homeobox 48 / 131
POU3F2 Pou 114 / 131
SMAD3 MH1 92 / 131
TGIF1 Homeobox 69 / 131
All CRCs of SF268
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC
Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
HOXA10 118 / 131 Homeobox ENSG00000253293
POU3F2 114 / 131 Pou ENSG00000184486
FOXG1 113 / 131 Fork_head ENSG00000176165
HOXC13 98 / 131 Homeobox ENSG00000123364
SMAD3 92 / 131 MH1 ENSG00000166949
HOXA4 81 / 131 Homeobox ENSG00000197576
HOXA5 81 / 131 Homeobox ENSG00000106004
HOXC12 81 / 131 Homeobox ENSG00000123407
HOXC10 78 / 131 Homeobox ENSG00000180818
HOXC11 70 / 131 Homeobox ENSG00000123388
TGIF1 69 / 131 Homeobox ENSG00000177426
BHLHE40 67 / 131 bHLH ENSG00000134107
HOXA3 66 / 131 Homeobox ENSG00000105997
HOXA7 65 / 131 Homeobox ENSG00000122592
HOXC9 54 / 131 Homeobox ENSG00000180806
FOSL2 54 / 131 TF_bZIP ENSG00000075426
MEIS2 48 / 131 Homeobox ENSG00000134138
EN1 44 / 131 Homeobox ENSG00000163064
HIC1 41 / 131 ZBTB ENSG00000177374
RFX2 41 / 131 RFX ENSG00000087903
HOXC4 39 / 131 Homeobox ENSG00000198353
HOXA2 33 / 131 Homeobox ENSG00000105996
MAFK 33 / 131 TF_bZIP ENSG00000198517
GBX2 32 / 131 Homeobox ENSG00000168505
DLX2 32 / 131 Homeobox ENSG00000115844
HOXA6 30 / 131 Homeobox ENSG00000106006
HOXC8 28 / 131 Homeobox ENSG00000037965
HOXA1 24 / 131 Homeobox ENSG00000105991
DLX1 24 / 131 Homeobox ENSG00000144355
HOXC5 23 / 131 Homeobox ENSG00000172789
NR2F2 23 / 131 RXR-like ENSG00000185551
TFAP2A 21 / 131 AP-2 ENSG00000137203
ERF 21 / 131 ETS ENSG00000105722
HOXC6 18 / 131 Homeobox ENSG00000197757
RUNX2 17 / 131 Runt ENSG00000124813
TEAD1 16 / 131 TEA ENSG00000187079
ZNF217 14 / 131 zf-C2H2 ENSG00000171940
FOXC2 14 / 131 Fork_head ENSG00000176692
NFATC2 13 / 131 RHD ENSG00000101096
CREB3L1 7 / 131 TF_bZIP ENSG00000157613
HOXB7 6 / 131 Homeobox ENSG00000260027
HOXB8 5 / 131 Homeobox ENSG00000120068
HES7 4 / 131 bHLH ENSG00000179111
YY1 4 / 131 zf-C2H2 ENSG00000100811
Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
HOXC9 50 59 109
HOXC8 50 45 95
NFATC2 20 59 79
YY1 16 63 79
FOXG1 49 68 117
HOXC5 50 46 96
ZNF217 35 43 78
SMAD3 49 61 110
ERF 40 46 86
MAFK 34 67 101
BHLHE40 49 49 98
TEAD1 20 64 84
HOXA10 51 64 115
RUNX2 22 65 87
HIC1 34 62 96
TFAP2A 39 62 101
MEIS2 46 59 105
NR2F2 44 55 99
EN1 45 59 104
HOXA4 51 53 104
FOSL2 46 55 101
DLX1 51 48 99
DLX2 51 44 95
HOXA2 51 44 95
POU3F2 51 67 118
HOXB8 37 51 88
GBX2 43 50 93
HOXB7 37 48 85
HOXC4 50 47 97
HOXC11 50 55 105
HOXC10 50 59 109
HOXC13 50 59 109
HOXC12 50 57 107
HOXC6 50 44 94
RFX2 49 53 102
FOXC2 23 67 90
HOXA7 51 54 105
HOXA6 51 45 96
HOXA5 51 58 109
CREB3L1 19 41 60
HOXA3 51 56 107
HOXA1 51 44 95
TGIF1 44 59 103
HES7 51 20 71

Expression of TFs in all CRCs

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Normal tissue (GTEx) Cell line (CCLE)