TF information

TF name: HOXA5
TF family: Homeobox
Ensembl gene ID: ENSG00000106004
Ensembl protein ID: ENSP00000222726
Entrez gene ID: 3202
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of HOXA5 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_021Cell lineColonV4290.56010377630441
Sample_02_069Cell lineBrainSF2680.61832061068702
Sample_02_114Cell lineMammary GlandCAL511
Sample_02_179Cell lineUrinary bladderT240.26436781609195
Sample_02_181Cell lineHuman melanomaCOLO6790.086933333333333
Sample_02_361Cell lineColonHT29_DMSO0.25309734513274

HOXA5 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_069BrainCell lineSF268
Sample_02_114Mammary GlandCell lineCAL51

HOXA5 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with HOXA5
Download

Mutation of HOXA5
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of HOXA5

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr72718310227183102GTexonicHOXA5nonsynonymous LUAD|1|543|0.00184
-chr72718273527182735GTexonicHOXA5nonsynonymous BRCA|1|982|0.00102
-chr72718276127182761TGexonicHOXA5nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr72718291527182915GAexonicHOXA5synonymous LUSC|1|178|0.00562
-chr72718148327181483CAexonicHOXA5nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr72718270427182704G-exonicHOXA5frameshift LUAD|1|543|0.00184
-chr72718305027183050CAexonicHOXA5synonymous LUAD|1|543|0.00184
-chr72718290527182905GAexonicHOXA5nonsynonymous SKCM|1|368|0.00272
rs764896847chr72718277927182779CTexonicHOXA5nonsynonymous LUAD|2|543|0.00368
-chr72718154627181546TCexonicHOXA5nonsynonymous HNSC|1|512|0.00195
-chr72718294927182949GAexonicHOXA5nonsynonymous STAD|2|395|0.00506,STES|2|395|0.00506
-chr72718284127182841GAexonicHOXA5nonsynonymous LUAD|1|543|0.00184
-chr72718309227183092GAexonicHOXA5synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr72718273427182734CTexonicHOXA5nonsynonymous BLCA|1|396|0.00253
-chr72718319627183196CAexonicHOXA5nonsynonymous LUAD|1|543|0.00184
-chr72718301627183016GTexonicHOXA5nonsynonymous LUAD|1|543|0.00184
-chr72718167227181672GAexonicHOXA5nonsynonymous LIHC|1|373|0.00268,STAD|1|395|0.00253,STES|1|395|0.00253
-chr72718313027183130GAexonicHOXA5stopgain UCEC|1|248|0.00403
-chr72718281427182814CAexonicHOXA5nonsynonymous PAAD|1|185|0.00541
-chr72718152727181527CTexonicHOXA5nonsynonymous SARC|1|247|0.00405
-chr72718304827183048CTexonicHOXA5nonsynonymous SKCM|2|368|0.00543
-chr72718292727182927CAexonicHOXA5synonymous LUAD|1|543|0.00184
-chr72718310127183101GTexonicHOXA5synonymous LUAD|1|543|0.00184
-chr72718168327181683CAexonicHOXA5nonsynonymous LUAD|1|543|0.00184
rs202017218chr72718274727182747CTexonicHOXA5synonymous LUAD|6|543|0.01105,PAAD|1|185|0.00541
-chr72718155327181553TCexonicHOXA5synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr72718165727181657GAexonicHOXA5nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr72718157327181573GCexonicHOXA5nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr72718155127181551AGexonicHOXA5nonsynonymous LUAD|1|543|0.00184
-chr72718158527181585TCexonicHOXA5nonsynonymous BRCA|1|982|0.00102
-chr72718148027181480CAexonicHOXA5nonsynonymous LUAD|4|543|0.00737
-chr72718283927182839CTexonicHOXA5nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr72718291627182916GAexonicHOXA5nonsynonymous BRCA|1|982|0.00102
-chr72718309727183097TAexonicHOXA5nonsynonymous LUAD|1|543|0.00184
-chr72718279227182792-GexonicHOXA5frameshift LUAD|1|543|0.00184
-chr72718276927182769GTexonicHOXA5nonsynonymous LUAD|1|543|0.00184
-chr72718162027181620ATexonicHOXA5nonsynonymous LUAD|1|543|0.00184
-chr72718280227182802CTexonicHOXA5nonsynonymous SKCM|2|368|0.00543
rs759617437chr72718168427181684CTexonicHOXA5nonsynonymous SKCM|1|368|0.00272
rs745560377chr72718146227181462GAexonicHOXA5nonsynonymous SKCM|1|368|0.00272
-chr72718287027182870TAexonicHOXA5nonsynonymous SKCM|1|368|0.00272
rs769142318chr72718146727181467GTexonicHOXA5nonsynonymous LUAD|1|543|0.00184
-chr72718283627182836CAexonicHOXA5nonsynonymous LUAD|1|543|0.00184
-chr72718290327182903G-exonicHOXA5frameshift BRCA|1|982|0.00102
-chr72718151027181510CAexonicHOXA5nonsynonymous UCEC|1|248|0.00403
-chr72718268527182685CTexonicHOXA5nonsynonymous PRAD|1|499|0.00200
-chr72718276727182767GTexonicHOXA5nonsynonymous LUAD|1|543|0.00184
-chr72718163227181633TT-exonicHOXA5frameshift COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr72718314527183145TCexonicHOXA5nonsynonymous ESCA|1|185|0.00541
-chr72718278427182784CTexonicHOXA5nonsynonymous LUAD|1|543|0.00184

Disease information of HOXA5
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
HOXA5 Diaphragmatic Hernia C23 Anatomical Abnormality CTD_human
HOXA5 Mouth Neoplasms C04;C07 Neoplastic Process CTD_human
HOXA5 Malignant neoplasm of mouth C04;C07 Neoplastic Process CTD_human
HOXA5 Squamous cell carcinoma of the head and neck C04 Neoplastic Process CTD_human

Pathway associated with HOXA5
pathway_ID pathway_name pathway_source gene_number edge_number

Go term information of HOXA5
GO_term_name GO_term_type TF_name
GO_LUNG_EPITHELIUM_DEVELOPMENT BP HOXA5
GO_RESPIRATORY_GASEOUS_EXCHANGE BP HOXA5
GO_REGULATION_OF_MAMMARY_GLAND_EPITHELIAL_CELL_PROLIFERATION BP HOXA5
GO_CARTILAGE_DEVELOPMENT BP HOXA5
GO_EPITHELIAL_TUBE_BRANCHING_INVOLVED_IN_LUNG_MORPHOGENESIS BP HOXA5
GO_LUNG_CELL_DIFFERENTIATION BP HOXA5
GO_MAMMARY_GLAND_EPITHELIUM_DEVELOPMENT BP HOXA5
GO_LUNG_MORPHOGENESIS BP HOXA5
GO_RESPIRATORY_SYSTEM_PROCESS BP HOXA5
GO_MAMMARY_GLAND_EPITHELIAL_CELL_DIFFERENTIATION BP HOXA5
GO_CARTILAGE_MORPHOGENESIS BP HOXA5
GO_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION BP HOXA5
GO_INTESTINAL_EPITHELIAL_CELL_DEVELOPMENT BP HOXA5
GO_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS BP HOXA5
GO_POSITIVE_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS BP HOXA5
GO_NEGATIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT BP HOXA5
GO_INTESTINAL_EPITHELIAL_CELL_DIFFERENTIATION BP HOXA5
GO_POSITIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION BP HOXA5
GO_REGULATION_OF_ERYTHROCYTE_DIFFERENTIATION BP HOXA5
GO_TRACHEA_DEVELOPMENT BP HOXA5
GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DEVELOPMENT BP HOXA5
GO_TRACHEA_MORPHOGENESIS BP HOXA5
GO_MESENCHYME_DEVELOPMENT BP HOXA5
GO_MAMMARY_GLAND_LOBULE_DEVELOPMENT BP HOXA5
GO_ENDOCRINE_SYSTEM_DEVELOPMENT BP HOXA5
GO_EMBRYONIC_ORGAN_DEVELOPMENT BP HOXA5
GO_EPITHELIAL_CELL_MATURATION BP HOXA5
GO_THYROID_GLAND_DEVELOPMENT BP HOXA5
GO_LUNG_ALVEOLUS_DEVELOPMENT BP HOXA5
GO_GLANDULAR_EPITHELIAL_CELL_DIFFERENTIATION BP HOXA5

Survival analysis of HOXA5



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of HOXA5