TF information

TF name: HOXC11
TF family: Homeobox
Ensembl gene ID: ENSG00000123388
Ensembl protein ID: ENSP00000446680
Entrez gene ID: 3227
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of HOXC11 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_01_001Cell lineProstate22Rv10.23244552058111
Sample_02_069Cell lineBrainSF2680.53435114503817
Sample_02_114Cell lineMammary GlandCAL510.71356783919598
Sample_02_357Cell lineColonColo3201
Sample_02_394Cell lineMammary GlandT-47D_20.15384615384615
Sample_02_395Cell lineMammary GlandBT-5490.8993006993007
Sample_02_403Cell lineMammary GlandT-47D_untreat0.45454545454545

HOXC11 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_069BrainCell lineSF268
Sample_02_357ColonCell lineColo320
Sample_02_395Mammary GlandCell lineBT-549
Sample_02_403Mammary GlandCell lineT-47D_untreat

HOXC11 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with HOXC11
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Mutation of HOXC11
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of HOXC11

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr125436756354367563GTexonicHOXC11stopgain BLCA|1|396|0.00253
rs755752688chr125436759754367597CTexonicHOXC11nonsynonymous ACC|1|90|0.01111
-chr125436715254367152GAexonicHOXC11nonsynonymous PAAD|1|185|0.00541
-chr125436730654367306CAexonicHOXC11nonsynonymous LUSC|1|178|0.00562
-chr125436703954367039TCexonicHOXC11nonsynonymous UCEC|1|248|0.00403
-chr125436902254369022TAexonicHOXC11nonsynonymous LUAD|1|543|0.00184
-chr125436715454367154GTexonicHOXC11nonsynonymous ESCA|1|185|0.00541
-chr125436907154369071GTexonicHOXC11synonymous LUAD|1|543|0.00184
-chr125436753254367532CTexonicHOXC11synonymous SKCM|1|368|0.00272
-chr125436757654367576CTexonicHOXC11nonsynonymous LIHC|1|373|0.00268
-chr125436743054367430CTexonicHOXC11synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr125436713954367139TGexonicHOXC11synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr125436909254369092CTexonicHOXC11synonymous GBM|1|290|0.00345,GBMLGG|1|820|0.00122
-chr125436736754367367CAexonicHOXC11synonymous HNSC|2|512|0.00391
rs778637728chr125436735354367353GAexonicHOXC11nonsynonymous PAAD|1|185|0.00541
-chr125436937354369373GAUTR3HOXC11unknown CESC|1|194|0.00515
-chr125436749954367499CTexonicHOXC11synonymous SKCM|1|368|0.00272
-chr125436920454369204GCUTR3HOXC11unknown ESCA|1|185|0.00541
-chr125436906254369062GAexonicHOXC11synonymous BRCA|1|982|0.00102
-chr125436908154369081CTexonicHOXC11nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs773152809chr125436746854367468CTexonicHOXC11nonsynonymous SKCM|1|368|0.00272
-chr125436746054367460CAexonicHOXC11nonsynonymous LUAD|1|543|0.00184
-chr125436733054367330GTexonicHOXC11nonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
rs750210157chr125436733054367330GAexonicHOXC11nonsynonymous BLCA|1|396|0.00253
-chr125436738354367383TAexonicHOXC11nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr125436901154369011GAexonicHOXC11synonymous SKCM|1|368|0.00272
-chr125436914654369146GCexonicHOXC11nonsynonymous LUAD|1|543|0.00184
-chr125436769254367692ATexonicHOXC11stopgain DLBC|1|48|0.02083
-chr125436742254367422ACexonicHOXC11nonsynonymous GBM|1|290|0.00345,GBMLGG|1|820|0.00122
-chr125436737654367376CTexonicHOXC11synonymous UCEC|1|248|0.00403
rs771475169chr125436719554367195GAexonicHOXC11nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr125436760554367605GAexonicHOXC11nonsynonymous BLCA|1|396|0.00253
-chr125436750554367505CTexonicHOXC11synonymous TGCT|1|155|0.00645
-chr125436707454367074GAexonicHOXC11nonsynonymous SKCM|1|368|0.00272
-chr125436758854367588GAexonicHOXC11nonsynonymous LUAD|1|543|0.00184
-chr125436715054367150CAexonicHOXC11nonsynonymous LIHC|1|373|0.00268
-chr125436911054369110GAexonicHOXC11synonymous LUAD|1|543|0.00184
-chr125436737054367370GAexonicHOXC11nonsynonymous CESC|1|194|0.00515
-chr125436916654369166TCexonicHOXC11nonsynonymous PRAD|1|499|0.00200
-chr125436769554367695GCexonicHOXC11nonsynonymous OV|1|469|0.00213
-chr125436734554367345CTexonicHOXC11nonsynonymous SKCM|1|368|0.00272
-chr125436728154367281CTexonicHOXC11nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs769147038chr125436739354367393GAexonicHOXC11nonsynonymous UCEC|1|248|0.00403
-chr125436753654367536TGexonicHOXC11nonsynonymous HNSC|1|512|0.00195
-chr125436726754367267GTexonicHOXC11nonsynonymous TGCT|1|155|0.00645
-chr125436756254367562GTexonicHOXC11synonymous THCA|1|504|0.00198
rs199765463chr125436709954367099GAexonicHOXC11nonsynonymous GBM|1|290|0.00345,GBMLGG|1|820|0.00122
-chr125436742854367428GAexonicHOXC11nonsynonymous PAAD|1|185|0.00541
-chr125436748754367487CAexonicHOXC11nonsynonymous UCEC|1|248|0.00403
-chr125436721654367216CGexonicHOXC11nonsynonymous LUAD|1|543|0.00184
-chr125436725754367257GTexonicHOXC11stopgain LUAD|1|543|0.00184
-chr125436710954367109CTexonicHOXC11synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr125436903454369034TCexonicHOXC11nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr125436728954367289CGexonicHOXC11nonsynonymous LUSC|1|178|0.00562

Disease information of HOXC11
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source

Pathway associated with HOXC11
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0002740 Hs_Endoderm_Differentiation_WP2853_88152 wikipathways 62 260

Go term information of HOXC11
GO_term_name GO_term_type TF_name
GO_METANEPHROS_DEVELOPMENT BP HOXC11
GO_EMBRYONIC_DIGIT_MORPHOGENESIS BP HOXC11
GO_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS BP HOXC11
GO_DEVELOPMENTAL_INDUCTION BP HOXC11
GO_REGULATION_OF_ORGAN_FORMATION BP HOXC11
GO_PROXIMAL_DISTAL_PATTERN_FORMATION BP HOXC11
GO_ORGAN_INDUCTION BP HOXC11
GO_ENDODERM_DEVELOPMENT BP HOXC11
GO_EMBRYONIC_MORPHOGENESIS BP HOXC11
GO_EMBRYONIC_SKELETAL_JOINT_DEVELOPMENT BP HOXC11
GO_TISSUE_DEVELOPMENT BP HOXC11
GO_REGULATORY_REGION_NUCLEIC_ACID_BINDING MF HOXC11
GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING MF HOXC11

Survival analysis of HOXC11



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of HOXC11