Sample overview of 22Rv1

Sample ID: Sample_01_001
Biosample type: Cell line
Tissue type: Prostate
Biosample name: 22Rv1
Data source: ENCODE
GSE ID: GSE105627|GSE105888
Cancer type: carcinoma (prostate)
CRC number: 413
TF number of all CRCs: 36
TF list of all CRCs: EHF, IRF2, KLF13, PBX1, YY1, HOXA10, NR2F2, MYC, TGIF1, SP1, HNF1A, HNF1B, ZBTB7B, NR4A1, HOXB3, ZNF217, HES1, SOX13, HOXC11, HOXA11, NFIX, PKNOX1, RARA, HOXC9, XBP1, HOXB8, HOXB2, RELA, ESR1, SMAD3, ETS2, PATZ1, E2F3, HOXC6, HOXC4, DLX5

The most representative CRC of 22Rv1
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Relationship plot of CRC model
TF number of this CRC: 9
CRC socre: 208.5556
TF list of the most representative CRC
TF name TF family Frequency of TFs
EHF ETS 381 / 413
HNF1B Homeobox 131 / 413
IRF2 IRF 241 / 413
KLF13 zf-C2H2 223 / 413
MYC bHLH 171 / 413
NR2F2 RXR-like 179 / 413
PBX1 Homeobox 199 / 413
TGIF1 Homeobox 156 / 413
YY1 zf-C2H2 196 / 413

All CRCs of 22Rv1
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
EHF 381 / 413 ETS ENSG00000135373
IRF2 241 / 413 IRF ENSG00000168310
KLF13 223 / 413 zf-C2H2 ENSG00000169926
PBX1 199 / 413 Homeobox ENSG00000185630
YY1 196 / 413 zf-C2H2 ENSG00000100811
HOXA10 187 / 413 Homeobox ENSG00000253293
NR2F2 179 / 413 RXR-like ENSG00000185551
MYC 171 / 413 bHLH ENSG00000136997
TGIF1 156 / 413 Homeobox ENSG00000177426
SP1 148 / 413 zf-C2H2 ENSG00000185591
HNF1A 138 / 413 Homeobox ENSG00000135100
HNF1B 131 / 413 Homeobox ENSG00000275410
ZBTB7B 125 / 413 ZBTB ENSG00000160685
NR4A1 118 / 413 NGFIB-like ENSG00000123358
HOXB3 114 / 413 Homeobox ENSG00000120093
ZNF217 113 / 413 zf-C2H2 ENSG00000171940
HES1 102 / 413 bHLH ENSG00000114315
SOX13 99 / 413 HMG ENSG00000143842
HOXC11 96 / 413 Homeobox ENSG00000123388
HOXA11 96 / 413 Homeobox ENSG00000005073
NFIX 95 / 413 CTF/NFI ENSG00000008441
PKNOX1 69 / 413 Homeobox ENSG00000160199
RARA 66 / 413 THR-like ENSG00000131759
HOXC9 63 / 413 Homeobox ENSG00000180806
XBP1 60 / 413 TF_bZIP ENSG00000100219
HOXB8 55 / 413 Homeobox ENSG00000120068
HOXB2 50 / 413 Homeobox ENSG00000173917
RELA 46 / 413 RHD ENSG00000173039
ESR1 36 / 413 ESR-like ENSG00000091831
SMAD3 32 / 413 MH1 ENSG00000166949
ETS2 30 / 413 ETS ENSG00000157557
PATZ1 25 / 413 ZBTB ENSG00000100105
E2F3 22 / 413 E2F ENSG00000112242
HOXC6 19 / 413 Homeobox ENSG00000197757
HOXC4 13 / 413 Homeobox ENSG00000198353
DLX5 4 / 413 Homeobox ENSG00000105880

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
HOXC9 31 48 79
ZNF217 41 35 76
YY1 34 56 90
HOXC4 31 35 66
SMAD3 25 55 80
HOXA10 36 54 90
XBP1 41 34 75
KLF13 36 54 90
ETS2 39 32 71
SOX13 32 52 84
HOXA11 36 47 83
NR2F2 38 48 86
HNF1B 40 49 89
HNF1A 33 57 90
HOXB3 40 44 84
DLX5 17 40 57
MYC 39 47 86
RARA 27 58 85
HOXB8 40 43 83
ZBTB7B 34 49 83
HOXB2 40 35 75
SP1 31 59 90
NR4A1 36 53 89
EHF 43 55 98
HES1 36 46 82
PATZ1 17 56 73
HOXC6 31 37 68
PKNOX1 43 41 84
PBX1 41 50 91
IRF2 39 56 95
RELA 35 41 76
E2F3 27 58 85
ESR1 24 55 79
HOXC11 31 52 83
NFIX 42 40 82
TGIF1 40 49 89

Expression of TFs in all CRCs