TF information

TF name: PATZ1
TF family: ZBTB
Ensembl gene ID: ENSG00000100105
Ensembl protein ID: ENSP00000337520, ENSP00000337520, ENSP00000215919, ENSP00000215919, ENSP00000266269, ENSP00000266269, ENSP00000384173
Entrez gene ID: 23598
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of PATZ1 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_01_001Cell lineProstate22Rv10.060532687651332
Sample_01_022Cell lineProstateC4-2B0.19047619047619
Sample_02_096Cell lineMammary GlandZR-75-1_10.10869565217391
Sample_02_404Cell lineMammary GlandZR-75-1_20.41726618705036

PATZ1 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name

PATZ1 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with PATZ1
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Mutation of PATZ1
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of PATZ1

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
rs749372022chr223173175231731752CTexonicPATZ1nonsynonymous PAAD|1|185|0.00541
-chr223174128231741282CGexonicPATZ1nonsynonymous CESC|2|194|0.01031
-chr223174109931741099GAexonicPATZ1synonymous BLCA|1|396|0.00253
rs770233611chr223173171531731715GAexonicPATZ1synonymous UCEC|1|248|0.00403
-chr223174116931741169GAexonicPATZ1synonymous SKCM|1|368|0.00272
-chr223174145731741457GAexonicPATZ1synonymous BLCA|1|396|0.00253
-chr223174033531740335AGexonicPATZ1synonymous SKCM|1|368|0.00272
rs551643471chr223172304531723045GAexonicPATZ1synonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs768984900chr223173175331731753GAexonicPATZ1nonsynonymous CHOL|1|35|0.02857,OV|1|469|0.00213
-chr223174073831740738CTexonicPATZ1nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr223174060431740604GCexonicPATZ1nonsynonymous BLCA|1|396|0.00253
-chr223174132531741325CTexonicPATZ1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr223173168131731681GAexonicPATZ1stopgain STAD|3|395|0.00759,STES|3|395|0.00759
-chr223174054231740542GTexonicPATZ1nonsynonymous ESCA|1|185|0.00541
-chr223172287831722878CGexonicPATZ1stoploss LUSC|1|178|0.00562
-chr223173741831737418CAexonicPATZ1nonsynonymous STAD|2|395|0.00506,STES|2|395|0.00506
-chr223174081531740815GAexonicPATZ1synonymous SKCM|1|368|0.00272
-chr223173763031737630GAexonicPATZ1nonsynonymous SKCM|1|368|0.00272
-chr223173181431731814CTexonicPATZ1synonymous BRCA|1|982|0.00102
-chr223172490631724906GTexonicPATZ1nonsynonymous UCEC|1|248|0.00403
-chr223174105531741055-GexonicPATZ1frameshift STAD|2|395|0.00506,STES|2|395|0.00506
-chr223174099231740992GAexonicPATZ1synonymous LUAD|1|543|0.00184
-chr223172299631722996GAexonicPATZ1nonsynonymous LUSC|1|178|0.00562
-chr223174142031741420CTexonicPATZ1nonsynonymous ACC|1|90|0.01111
-chr223174040831740408CTexonicPATZ1nonsynonymous SKCM|1|368|0.00272
-chr223173170531731705TCexonicPATZ1nonsynonymous UCEC|1|248|0.00403
-chr223173755331737553GAexonicPATZ1synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr223173760631737606AGexonicPATZ1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr223174079631740796GAexonicPATZ1stopgain HNSC|1|512|0.00195
rs763469287chr223172293531722935GAexonicPATZ1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr223172479231724792GAexonicPATZ1stopgain LIHC|1|373|0.00268
-chr223174059831740598GCexonicPATZ1nonsynonymous UCEC|1|248|0.00403
-chr223173181331731813GAexonicPATZ1nonsynonymous PRAD|1|499|0.00200,STAD|1|395|0.00253,STES|1|395|0.00253
-chr223174124631741246CAexonicPATZ1nonsynonymous UCEC|1|248|0.00403
-chr223174070631740706CAexonicPATZ1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr223173888531738885GAexonicPATZ1stopgain BLCA|1|396|0.00253
-chr223173893431738934CGexonicPATZ1nonsynonymous SKCM|1|368|0.00272
-chr223172302931723029C-exonicPATZ1frameshift LIHC|1|373|0.00268
-chr223172313031723131TT-exonicPATZ1frameshift ESCA|1|185|0.00541
-chr223172297231722972CGexonicPATZ1nonsynonymous LUAD|4|543|0.00737
rs139600326chr223172305431723054GAexonicPATZ1synonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs140597902chr223174126231741262GAexonicPATZ1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs759161425chr223174084231740842GAexonicPATZ1synonymous SKCM|2|368|0.00543
rs373917062chr223173757531737575GAexonicPATZ1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr223174112931741129CAexonicPATZ1stopgain CESC|1|194|0.00515
-chr223172479931724799TCexonicPATZ1nonsynonymous UCEC|1|248|0.00403
-chr223172290931722909CGexonicPATZ1nonsynonymous BLCA|1|396|0.00253
-chr223173763331737633CTexonicPATZ1nonsynonymous HNSC|1|512|0.00195
-chr223172305231723052CTexonicPATZ1nonsynonymous SARC|1|247|0.00405
-chr223173185031731850CGsplicingPATZ1splicing BLCA|1|396|0.00253
-chr223174132231741322GAexonicPATZ1synonymous LUSC|1|178|0.00562
rs766392086chr223172322431723224CTexonicPATZ1nonsynonymous PRAD|1|499|0.00200
rs765835799chr223173764131737641GAexonicPATZ1nonsynonymous ESCA|1|185|0.00541
-chr223174071531740715GTexonicPATZ1nonsynonymous SARC|1|247|0.00405
-chr223174116531741165ATexonicPATZ1nonsynonymous LUAD|2|543|0.00368
-chr223174115031741150ATexonicPATZ1nonsynonymous ESCA|1|185|0.00541
-chr223174111431741114AGexonicPATZ1nonsynonymous KICH|1|66|0.01515,KIPAN|1|799|0.00125
-chr223174047531740475GAexonicPATZ1nonsynonymous PAAD|1|185|0.00541
-chr223173176331731763CTexonicPATZ1synonymous HNSC|1|512|0.00195
-chr223174147331741473CAexonicPATZ1nonsynonymous ACC|1|90|0.01111
-chr223172316631723166AGexonicPATZ1nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr223174057331740573GCexonicPATZ1nonsynonymous CESC|1|194|0.00515
-chr223174079531740795CTexonicPATZ1nonsynonymous BLCA|1|396|0.00253,LUSC|1|178|0.00562
-chr223174133531741335GAexonicPATZ1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr223174035631740356CTexonicPATZ1synonymous UCEC|1|248|0.00403
-chr223172323931723239GAexonicPATZ1nonsynonymous LUAD|1|543|0.00184
rs757918024chr223174154531741545TCexonicPATZ1nonsynonymous LUAD|1|543|0.00184
-chr223172482831724828CGexonicPATZ1nonsynonymous ESCA|1|185|0.00541
-chr223174129431741294CGexonicPATZ1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr223173739931737399CTexonicPATZ1nonsynonymous BLCA|1|396|0.00253
rs377660548chr223174106231741062CTexonicPATZ1nonsynonymous HNSC|1|512|0.00195
-chr223172298031722980GTexonicPATZ1nonsynonymous BLCA|1|396|0.00253
-chr223172298031722980GAexonicPATZ1nonsynonymous SKCM|2|368|0.00543
-chr223174106331741063GAexonicPATZ1nonsynonymous SKCM|1|368|0.00272
-chr223173894231738942CTexonicPATZ1nonsynonymous SKCM|1|368|0.00272
-chr223173890831738908GAexonicPATZ1nonsynonymous BLCA|1|396|0.00253
-chr223172298731722987TAexonicPATZ1nonsynonymous LUAD|1|543|0.00184
-chr223174056231740562CTexonicPATZ1nonsynonymous SARC|1|247|0.00405
-chr223172320131723201CTexonicPATZ1synonymous BLCA|1|396|0.00253
-chr223174105631741056G-exonicPATZ1frameshift COAD|2|367|0.00545,COADREAD|2|489|0.00409
rs751106943chr223174047331740473CTexonicPATZ1synonymous ACC|1|90|0.01111,PAAD|2|185|0.01081
-chr223172489731724897GCexonicPATZ1synonymous LUSC|1|178|0.00562
-chr223173764231737642GAexonicPATZ1nonsynonymous BLCA|1|396|0.00253
-chr223174038631740386-TexonicPATZ1frameshift CESC|1|194|0.00515
-chr223174147931741479CTexonicPATZ1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr223174108131741081CGexonicPATZ1nonsynonymous LUAD|1|543|0.00184
-chr223174132131741321CAexonicPATZ1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr223174038231740382GAexonicPATZ1nonsynonymous PAAD|1|185|0.00541
-chr223174139831741398TCexonicPATZ1nonsynonymous UCEC|1|248|0.00403
-chr223172309431723094GCexonicPATZ1nonsynonymous UCEC|1|248|0.00403
-chr223174148331741483TAexonicPATZ1nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr223174141531741415CTexonicPATZ1synonymous DLBC|1|48|0.02083
-chr223174140431741404CTexonicPATZ1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253

Disease information of PATZ1
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source

Pathway associated with PATZ1
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0000492 Coregulation of Androgen receptor activity pid 61 268
pathway0002863 Hs_Androgen_receptor_signaling_pathway_WP138_79958 wikipathways 27 107

Go term information of PATZ1
GO_term_name GO_term_type TF_name
GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION BP PATZ1
GO_POSITIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS BP PATZ1

Survival analysis of PATZ1



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of PATZ1