Cancer CRCdb

TF information

TF name:	MYC
TF family:	bHLH
Ensembl gene ID:	ENSG00000136997
Ensembl protein ID:	ENSP00000367207, ENSP00000430235, ENSP00000479618, ENSP00000478887
Entrez gene ID:	4609

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of MYC in all biosamples

Download

Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_01_001	Cell line	Prostate	22Rv1	0.41404358353511
Sample_01_022	Cell line	Prostate	C4-2B	0.26190476190476
Sample_01_059	Cell line	Lung	PC-9	0.33333333333333
Sample_01_068	Cell line	Prostate: derived from metastatic site: vertebral metastasis	VCaP	0.36986301369863
Sample_02_021	Cell line	Colon	V429	0.82819256269818
Sample_02_080	Cell line	Lung	Calu-3	0.13636363636364
Sample_02_095	Cell line	Mammary Gland	MDA-MB-468	0.59922178988327
Sample_02_096	Cell line	Mammary Gland	ZR-75-1_1	0.57608695652174
Sample_02_164	Cell line	Lung	H2087_Parental	0.2
Sample_02_166	Cell line	Mammary Gland	HCC1954_Parental	1
Sample_02_168	Cell line	Prostate	LNCaP	0.42205323193916
Sample_02_182	Cell line	Human melanoma	LOX-IMVI	0.10919540229885
Sample_02_187	Cell line	Stomach	KATOIII	0.33333333333333
Sample_02_189	Cell line	Stomach	SNU016	1
Sample_02_191	Cell line	Stomach	SNU719	0.28571428571429
Sample_02_195	Cell line	Stomach	OCUM1	1
Sample_02_196	Cell line	Stomach	NCC59	0.57142857142857
Sample_02_198	Cell line	Stomach	SNU16	1
Sample_02_199	Cell line	Stomach	KATO3	0.66666666666667
Sample_02_208	Cell line	Stomach	YCC3	0.875
Sample_02_219	Cell line	Mammary Gland	MDA-MB-231	0.2156862745098
Sample_02_227	Cell line	Oesophagus	TE7	0.36
Sample_02_228	Cell line	Oesophagus	KYSE510	0.26840633737185
Sample_02_236	Cell line	Colon	V206	0.70807453416149
Sample_02_237	Cell line	Colon	V389	0.22609976072152
Sample_02_241	Cell line	Colon	V456	0.31489841986456
Sample_02_250	Tissue	Brain	tumormodel3691	0.53125
Sample_02_258	Other	Lung	NCI-H1299_EGFP-NEO_reporter_cells_DMSO	0.14444444444444
Sample_02_268	Cell line	Kidney	A-498	0.36274690788259
Sample_02_317	Cell line	Neuroblastoma	GICAN	0.054054054054054
Sample_02_318	Cell line	Neuroblastoma	NB69	0.3046875
Sample_02_323	Cell line	Colon	RKO	0.5
Sample_02_354	Cell line	Colon	Colo205	0.3048048048048
Sample_02_356	Cell line	Colon	Sw480	0.27741935483871
Sample_02_358	Cell line	Colon	LS180	0.15205371248025
Sample_02_361	Cell line	Colon	HT29_DMSO	0.21061946902655
Sample_02_395	Cell line	Mammary Gland	BT-549	0.26125874125874
Sample_02_424	Cell line	Colon	SW620	0.5

MYC distribution in samples’ most representative CRC

Download

Sample ID	Tissue type	Biosample type	Biosample name
Sample_01_001	Prostate	Cell line	22Rv1
Sample_02_021	Colon	Cell line	V429
Sample_02_164	Lung	Cell line	H2087_Parental
Sample_02_166	Mammary Gland	Cell line	HCC1954_Parental
Sample_02_187	Stomach	Cell line	KATOIII
Sample_02_189	Stomach	Cell line	SNU016
Sample_02_195	Stomach	Cell line	OCUM1
Sample_02_198	Stomach	Cell line	SNU16
Sample_02_199	Stomach	Cell line	KATO3
Sample_02_208	Stomach	Cell line	YCC3
Sample_02_236	Colon	Cell line	V206
Sample_02_318	Neuroblastoma	Cell line	NB69
Sample_02_424	Colon	Cell line	SW620

MYC distribution in all CRCs

Genomic distribution of SEs associated with MYC

Download

Mutation of MYC

Download

Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of MYC

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr8	128750836	128750836	A	T	exonic	MYC	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr8	128750735	128750735	C	T	exonic	MYC	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr8	128753130	128753130	G	A	exonic	MYC	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr8	128750844	128750844	C	T	exonic	MYC	synonymous	DLBC\|1\|48\|0.02083
-	chr8	128753053	128753053	C	-	exonic	MYC	frameshift	PAAD\|1\|185\|0.00541
-	chr8	128752800	128752800	C	G	exonic	MYC	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr8	128752802	128752802	G	C	exonic	MYC	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr8	128752816	128752816	C	G	exonic	MYC	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr8	128751021	128751021	C	T	exonic	MYC	synonymous	DLBC\|1\|48\|0.02083
rs751465079	chr8	128751084	128751084	G	T	exonic	MYC	synonymous	BLCA\|1\|396\|0.00253
-	chr8	128750880	128750880	C	T	exonic	MYC	synonymous	CESC\|1\|194\|0.00515
-	chr8	128752827	128752827	A	-	exonic	MYC	frameshift	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
-	chr8	128752831	128752831	G	T	exonic	MYC	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs121918684	chr8	128750625	128750625	G	C	exonic	MYC	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr8	128750945	128750945	C	T	exonic	MYC	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,HNSC\|3\|512\|0.00586,LUAD\|1\|543\|0.00184,SKCM\|1\|368\|0.00272
-	chr8	128750559	128750559	C	G	exonic	MYC	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr8	128752907	128752907	A	G	exonic	MYC	synonymous	DLBC\|1\|48\|0.02083
-	chr8	128753157	128753157	G	A	exonic	MYC	nonsynonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr8	128750895	128750895	C	T	exonic	MYC	synonymous	ESCA\|1\|185\|0.00541
-	chr8	128752674	128752675	GT	-	exonic	MYC	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr8	128750536	128750536	A	G	exonic	MYC	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr8	128752732	128752732	C	A	exonic	MYC	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr8	128750987	128750987	G	A	exonic	MYC	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr8	128750708	128750708	C	T	exonic	MYC	nonsynonymous	SKCM\|1\|368\|0.00272
rs775522201	chr8	128750639	128750639	C	T	exonic	MYC	nonsynonymous	UCS\|1\|57\|0.01754
-	chr8	128750606	128750607	AG	-	exonic	MYC	frameshift	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122,PAAD\|12\|185\|0.06486,PRAD\|2\|499\|0.00401,UCS\|1\|57\|0.01754
rs753250129	chr8	128750809	128750809	A	G	exonic	MYC	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr8	128750604	128750604	-	AG	exonic	MYC	frameshift	SARC\|1\|247\|0.00405
-	chr8	128752858	128752858	T	A	exonic	MYC	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr8	128752825	128752825	C	T	exonic	MYC	nonsynonymous	CESC\|1\|194\|0.00515
-	chr8	128750529	128750529	C	A	exonic	MYC	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr8	128751013	128751013	A	T	exonic	MYC	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr8	128750924	128750924	C	G	exonic	MYC	nonsynonymous	BLCA\|1\|396\|0.00253,HNSC\|1\|512\|0.00195
-	chr8	128750933	128750933	C	T	exonic	MYC	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr8	128751032	128751032	G	A	exonic	MYC	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr8	128750739	128750739	C	G	exonic	MYC	synonymous	LUSC\|1\|178\|0.00562
-	chr8	128750683	128750683	C	T	exonic	MYC	nonsynonymous	SARC\|1\|247\|0.00405,SKCM\|1\|368\|0.00272
-	chr8	128750777	128750777	G	A	exonic	MYC	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr8	128750771	128750771	G	A	exonic	MYC	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr8	128752960	128752960	A	G	exonic	MYC	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr8	128750820	128750820	G	A	exonic	MYC	synonymous	DLBC\|1\|48\|0.02083
-	chr8	128752882	128752882	T	C	exonic	MYC	nonsynonymous	THCA\|1\|504\|0.00198
-	chr8	128750529	128750529	C	G	exonic	MYC	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr8	128750653	128750766	ATCTGGAAGAAATTCGAGCTGCTGCCCACCCCGCCCCTGTCCCCTAGCCGCCGCTCCGGGCTCTGCTCGCCCTCCTACGTTGCGGTCACACCCTTCTCCCTTCGGGGAGACAAC	-	exonic	MYC	nonframeshift	-
-	chr8	128753114	128753114	G	A	exonic	MYC	synonymous	HNSC\|2\|512\|0.00391
-	chr8	128748845	128748845	T	-	exonic	MYC	frameshift	PAAD\|1\|185\|0.00541
-	chr8	128752945	128752945	T	A	exonic	MYC	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr8	128753051	128753051	G	C	exonic	MYC	nonsynonymous	HNSC\|1\|512\|0.00195
rs777976423	chr8	128752802	128752802	G	A	exonic	MYC	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr8	128753073	128753073	A	-	exonic	MYC	frameshift	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr8	128752989	128752989	G	A	exonic	MYC	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr8	128751001	128751001	G	A	exonic	MYC	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr8	128750683	128750683	C	A	exonic	MYC	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr8	128753004	128753004	T	C	exonic	MYC	nonsynonymous	UCS\|1\|57\|0.01754
-	chr8	128753090	128753090	C	T	exonic	MYC	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr8	128750613	128750613	G	A	exonic	MYC	synonymous	DLBC\|1\|48\|0.02083
-	chr8	128753024	128753024	G	T	exonic	MYC	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr8	128751156	128751156	C	T	exonic	MYC	synonymous	ESCA\|1\|185\|0.00541,OV\|1\|469\|0.00213
-	chr8	128751076	128751076	G	C	exonic	MYC	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr8	128751083	128751083	C	T	exonic	MYC	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr8	128750661	128750661	G	A	exonic	MYC	synonymous	BLCA\|1\|396\|0.00253
rs61752959	chr8	128750607	128750607	G	C	exonic	MYC	nonsynonymous	LIHC\|1\|373\|0.00268,TGCT\|1\|155\|0.00645
-	chr8	128752784	128752784	C	T	exonic	MYC	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr8	128753006	128753006	T	A	exonic	MYC	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr8	128750661	128750661	G	T	exonic	MYC	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr8	128750684	128750684	C	T	exonic	MYC	nonsynonymous	LAML\|1\|197\|0.00508,SARC\|1\|247\|0.00405,SKCM\|2\|368\|0.00543
-	chr8	128753094	128753094	C	A	exonic	MYC	nonsynonymous	UCEC\|1\|248\|0.00403

Disease information of MYC

Download

TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
MYC	Adenocarcinoma	C04	Neoplastic Process	CTD_human
MYC	Malignant neoplasm of urinary bladder	C04;C12;C13	Neoplastic Process	CTD_human
MYC	Bladder Neoplasm	C04;C12;C13	Neoplastic Process	CTD_human
MYC	Burkitt Lymphoma	C02;C04;C15;C20	Neoplastic Process	CGI;CTD_human;ORPHANET;UNIPROT
MYC	Malignant Neoplasms	C04	Neoplastic Process	CGI;CTD_human
MYC	Carcinoma	C04	Neoplastic Process	CTD_human
MYC	Malignant tumor of colon	C04;C06	Neoplastic Process	CTD_human
MYC	Adenocarcinoma of prostate		Neoplastic Process	CGI
MYC	Merkel cell carcinoma	C02;C04	Neoplastic Process	CTD_human
MYC	Non-Small Cell Lung Carcinoma	C04;C08	Neoplastic Process	CTD_human
MYC	Squamous cell carcinoma	C04	Neoplastic Process	CTD_human
MYC	Hypertrophic Cardiomyopathy	C14	Disease or Syndrome	CTD_human
MYC	Neoplastic Cell Transformation	C04;C23	Neoplastic Process	CTD_human
MYC	Uterine Cervical Neoplasm	C04;C13	Neoplastic Process	CTD_human
MYC	Cleft upper lip	C07;C16	Congenital Abnormality	CTD_human
MYC	Cleft Palate	C05;C07;C16	Congenital Abnormality	CTD_human
MYC	Colonic Neoplasms	C04;C06	Neoplastic Process	CTD_human
MYC	Endometrial Neoplasms	C04;C13	Neoplastic Process	CTD_human
MYC	Fatty Liver	C06	Disease or Syndrome	CTD_human
MYC	Glioblastoma	C04	Neoplastic Process	CTD_human
MYC	Hemangiosarcoma	C04	Neoplastic Process	CTD_human
MYC	Hepatoma, Morris	C04;C06	Experimental Model of Disease; Neoplastic Process	CTD_human
MYC	Hepatoma, Novikoff	C04;C06	Experimental Model of Disease; Neoplastic Process	CTD_human
MYC	Chronic Lymphocytic Leukemia	C04;C15;C20	Neoplastic Process	CGI
MYC	Leukemia, Myelocytic, Acute	C04	Neoplastic Process	CTD_human
MYC	Liver Cirrhosis, Experimental	C06	Experimental Model of Disease	CTD_human
MYC	Liver neoplasms	C04;C06	Neoplastic Process	CTD_human
MYC	Liver Neoplasms, Experimental	C04;C06	Experimental Model of Disease; Neoplastic Process	CTD_human
MYC	Lung Neoplasms	C04;C08	Neoplastic Process	CTD_human
MYC	Malignant neoplasm of stomach	C04;C06	Neoplastic Process	CTD_human
MYC	Medulloblastoma	C04	Neoplastic Process	CTD_human
MYC	Multiple Myeloma	C04;C14;C15;C20	Neoplastic Process	CGI
MYC	Acute Myeloid Leukemia, M1	C04	Neoplastic Process	CTD_human
MYC	Neoplasm Metastasis	C04;C23	Neoplastic Process	CTD_human
MYC	Neoplasms	C04	Neoplastic Process	CTD_human
MYC	Neuroblastoma	C04	Neoplastic Process	CGI;CTD_human
MYC	Osteosarcoma	C04	Neoplastic Process	CTD_human
MYC	Pancreatic Neoplasm	C04;C06;C19	Neoplastic Process	CTD_human
MYC	Prostatic Neoplasms	C04;C12	Neoplastic Process	CTD_human
MYC	Stomach Neoplasms	C04;C06	Neoplastic Process	CTD_human
MYC	Lymphoma, Small Noncleaved-Cell	C04;C15;C20	Neoplastic Process	ORPHANET
MYC	Polycystic Kidney, Autosomal Dominant	C12;C13;C16	Disease or Syndrome	CTD_human
MYC	Experimental Hepatoma	C04;C06	Experimental Model of Disease; Neoplastic Process	CTD_human
MYC	Benign Neoplasm	C04	Neoplastic Process	CTD_human
MYC	Left Ventricular Hypertrophy	C14;C23	Disease or Syndrome	CTD_human
MYC	Adenocarcinoma of lung (disorder)	C04;C08	Neoplastic Process	CTD_human
MYC	Adenocarcinoma, Basal Cell	C04	Neoplastic Process	CTD_human
MYC	Adenocarcinoma, Oxyphilic	C04	Neoplastic Process	CTD_human
MYC	Carcinoma, Cribriform	C04	Neoplastic Process	CTD_human
MYC	Carcinoma, Granular Cell	C04	Neoplastic Process	CTD_human
MYC	Adenocarcinoma, Tubular	C04	Neoplastic Process	CTD_human
MYC	Anaplastic carcinoma	C04	Neoplastic Process	CTD_human
MYC	Carcinoma, Spindle-Cell	C04	Neoplastic Process	CTD_human
MYC	Undifferentiated carcinoma	C04	Neoplastic Process	CTD_human
MYC	Carcinomatosis	C04	Neoplastic Process	CTD_human
MYC	Medullomyoblastoma	C04	Neoplastic Process	CTD_human
MYC	Neuroectodermal Tumors	C04	Neoplastic Process	CTD_human
MYC	Disease Exacerbation	C23	Finding	CTD_human
MYC	Malignant neoplasm of lung	C04;C08	Neoplastic Process	CTD_human
MYC	Childhood Medulloblastoma	C04	Neoplastic Process	CTD_human
MYC	Adult Medulloblastoma	C04	Neoplastic Process	CTD_human
MYC	Chromosome Breaks	C23	Cell or Molecular Dysfunction	CTD_human
MYC	Giant Cell Glioblastoma	C04	Neoplastic Process	CTD_human
MYC	African Burkitt's lymphoma	C02;C04;C15;C20	Neoplastic Process	CTD_human
MYC	Malignant neoplasm of liver	C04;C06	Neoplastic Process	CTD_human
MYC	Malignant neoplasm of pancreas	C04;C06;C19	Neoplastic Process	CTD_human
MYC	Malignant neoplasm of prostate	C04;C12	Neoplastic Process	CTD_human
MYC	Chromosome Breakage	C23	Cell or Molecular Dysfunction	CTD_human
MYC	Endometrial Carcinoma	C04;C13	Neoplastic Process	CTD_human
MYC	Desmoplastic Medulloblastoma	C04	Neoplastic Process	CTD_human
MYC	Polycystic Kidney, Type 1 Autosomal Dominant Disease	C12;C13;C16	Congenital Abnormality; Disease or Syndrome	CTD_human
MYC	ovarian neoplasm	C04;C13;C19	Neoplastic Process	CTD_human
MYC	Malignant neoplasm of ovary	C04;C13;C19	Neoplastic Process	CTD_human
MYC	Melanotic medulloblastoma	C04	Neoplastic Process	CTD_human
MYC	Glioblastoma Multiforme	C04	Neoplastic Process	CTD_human
MYC	Hereditary Diffuse Gastric Cancer	C04;C06	Neoplastic Process	CTD_human
MYC	Cleft palate, isolated	C05;C07;C16	Congenital Abnormality	CTD_human
MYC	Acute Myeloid Leukemia (AML-M2)	C04	Neoplastic Process	CTD_human
MYC	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	C04;C15;C20	Neoplastic Process	ORPHANET
MYC	Liver carcinoma	C04;C06	Neoplastic Process	CTD_human
MYC	Steatohepatitis	C06	Disease or Syndrome	CTD_human
MYC	Hematopoetic Myelodysplasia	C15	Pathologic Function	CTD_human
MYC	Polycystic kidney disease, type 2	C12;C13;C16	Disease or Syndrome	CTD_human
MYC	MYELODYSPLASTIC SYNDROME	C15	Neoplastic Process	CTD_human
MYC	cervical cancer	C04;C13	Neoplastic Process	CTD_human

Pathway associated with MYC

Download

pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0000309	Binding of TCF/LEF:CTNNB1 to target gene promoters	reactome	7	20
pathway0000336	C-MYC pathway	pid	25	112
pathway0000388	CD40/CD40L signaling	pid	36	298
pathway0000403	Ceramide signaling pathway	pid	49	409
pathway0000483	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	reactome	57	500
pathway0000484	Constitutive Signaling by NOTCH1 PEST Domain Mutants	reactome	57	500
pathway0000515	Cyclin A:Cdk2-associated events at S phase entry	reactome	15	73
pathway0000518	Cyclin E associated events during G1/S transition	reactome	14	63
pathway0000648	E2F transcription factor network	pid	77	897
pathway0000826	FOXM1 transcription factor network	pid	43	294
pathway0001119	IL2-mediated signaling events	pid	54	871
pathway0001121	IL2 signaling events mediated by PI3K	pid	38	397
pathway0001122	IL2 signaling events mediated by STAT5	pid	30	232
pathway0001131	IL6-mediated signaling events	pid	48	426
pathway0001287	LKB1 signaling events	pid	43	314
pathway0001322	MAPK6/MAPK4 signaling	reactome	90	1485
pathway0001523	Notch signaling pathway	pid	58	321
pathway0001524	NOTCH1 Intracellular Domain Regulates Transcription	reactome	47	463
pathway0001560	Oxidative stress response	panther	23	125
pathway0001581	p53 pathway feedback loops 2	panther	42	372
pathway0001714	Presenilin action in Notch and Wnt signaling	pid	46	287
pathway0001848	Regulation of nuclear beta catenin signaling and target gene transcription	pid	80	611
pathway0001861	Regulation of Telomerase	pid	70	708
pathway0002069	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	reactome	32	197
pathway0002388	Validated nuclear estrogen receptor alpha network	pid	65	386
pathway0002390	Validated targets of C-MYC transcriptional activation	pid	80	573
pathway0002391	Validated targets of C-MYC transcriptional repression	pid	63	385
pathway0002564	ErbB signaling pathway	kegg	83	1425
pathway0002591	TGF-beta signaling pathway	kegg	82	1017
pathway0002657	Colorectal cancer	kegg	63	642
pathway0002660	Endometrial cancer	kegg	52	567
pathway0002663	Thyroid cancer	kegg	25	123
pathway0002666	Bladder cancer	kegg	38	233
pathway0002667	Chronic myeloid leukemia	kegg	69	881
pathway0002668	Acute myeloid leukemia	kegg	53	562
pathway0002669	Small cell lung cancer	kegg	83	807
pathway0002691	Hs_DNA_Damage_Response_(only_ATM_dependent)_WP710_79974	wikipathways	36	219
pathway0002692	Hs_TP53_Network_WP1742_71700	wikipathways	10	32
pathway0002693	Hs_Imatinib_and_Chronic_Myeloid_Leukemia_WP3640_89384	wikipathways	11	19
pathway0002697	Hs_miRNAs_involved_in_DNA_damage_response_WP1545_84697	wikipathways	30	76
pathway0002701	Hs_Association_Between_Physico-Chemical_Features_and_Toxicity_Associated_Pathways_WP3680_90113	wikipathways	31	223
pathway0002713	Hs_Gastric_Cancer_Network_2_WP2363_87523	wikipathways	28	82
pathway0002717	Hs_Hepatitis_C_and_Hepatocellular_Carcinoma_WP3646_88640	wikipathways	36	226
pathway0002719	Hs_Apoptosis_WP254_88977	wikipathways	31	127
pathway0002747	Hs_Neural_Crest_Differentiation_WP2064_79263	wikipathways	40	129
pathway0002757	Hs_Pathways_Affected_in_Adenoid_Cystic_Carcinoma_WP3651_89271	wikipathways	27	108
pathway0002837	Hs_IL-5_Signaling_Pathway_WP127_78498	wikipathways	35	321
pathway0002860	Hs_Prolactin_Signaling_Pathway_WP2037_90015	wikipathways	52	570
pathway0002872	Hs_IL-7_Signaling_Pathway_WP205_89854	wikipathways	16	85

Go term information of MYC

Download

GO_term_name	GO_term_type	TF_name
GO_POSITIVE_REGULATION_OF_METANEPHROS_DEVELOPMENT	BP	MYC
GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING	BP	MYC
GO_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT	BP	MYC
GO_POSITIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS	BP	MYC
GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY	BP	MYC
GO_NEGATIVE_REGULATION_OF_CELL_DIVISION	BP	MYC
GO_CELLULAR_RESPONSE_TO_UV	BP	MYC
GO_ENERGY_RESERVE_METABOLIC_PROCESS	BP	MYC
GO_EMBRYONIC_DIGIT_MORPHOGENESIS	BP	MYC
GO_NEGATIVE_REGULATION_OF_GLIOGENESIS	BP	MYC
GO_EMBRYONIC_SKELETAL_SYSTEM_DEVELOPMENT	BP	MYC
GO_CELLULAR_RESPONSE_TO_LIGHT_STIMULUS	BP	MYC
GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS	BP	MYC
GO_POSITIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION	BP	MYC
GO_POSITIVE_REGULATION_OF_KIDNEY_DEVELOPMENT	BP	MYC
GO_REGULATION_OF_KINASE_ACTIVITY	BP	MYC
GO_TISSUE_MORPHOGENESIS	BP	MYC
GO_NEGATIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION	BP	MYC
GO_CELLULAR_IRON_ION_HOMEOSTASIS	BP	MYC
GO_CELL_CYCLE_ARREST	BP	MYC
GO_NEGATIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION	BP	MYC
GO_NEGATIVE_REGULATION_OF_ASTROCYTE_DIFFERENTIATION	BP	MYC
GO_REGULATION_OF_ASTROCYTE_DIFFERENTIATION	BP	MYC
GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION	BP	MYC
GO_REGULATION_OF_TELOMERE_MAINTENANCE	BP	MYC
GO_REGULATION_OF_CELL_PROLIFERATION_INVOLVED_IN_KIDNEY_DEVELOPMENT	BP	MYC
GO_REGULATION_OF_KIDNEY_DEVELOPMENT	BP	MYC
GO_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION	BP	MYC
GO_CANONICAL_WNT_SIGNALING_PATHWAY	BP	MYC
GO_CHROMATIN_MODIFICATION	BP	MYC
GO_NEPHRON_EPITHELIUM_DEVELOPMENT	BP	MYC
GO_NEGATIVE_REGULATION_OF_HEMOPOIESIS	BP	MYC
GO_REGULATION_OF_FIBROBLAST_PROLIFERATION	BP	MYC
GO_CELL_AGGREGATION	BP	MYC
GO_RENAL_TUBULE_DEVELOPMENT	BP	MYC
GO_GAS_TRANSPORT	BP	MYC
GO_BRANCHING_INVOLVED_IN_URETERIC_BUD_MORPHOGENESIS	BP	MYC
GO_NEGATIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION	BP	MYC
GO_OXYGEN_TRANSPORT	BP	MYC
GO_POSITIVE_REGULATION_OF_CELL_DEATH	BP	MYC
GO_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION	BP	MYC
GO_REGULATION_OF_METANEPHROS_DEVELOPMENT	BP	MYC
GO_REGULATION_OF_MONOCYTE_DIFFERENTIATION	BP	MYC
GO_GAMETE_GENERATION	BP	MYC
GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE	BP	MYC
GO_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS	BP	MYC
GO_NEGATIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE	BP	MYC
GO_RESPONSE_TO_GAMMA_RADIATION	BP	MYC
GO_CONNECTIVE_TISSUE_DEVELOPMENT	BP	MYC
GO_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION	BP	MYC
GO_RESPIRATORY_SYSTEM_DEVELOPMENT	BP	MYC
GO_POSITIVE_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION	BP	MYC
GO_CELLULAR_TRANSITION_METAL_ION_HOMEOSTASIS	BP	MYC
GO_KIDNEY_MORPHOGENESIS	BP	MYC
GO_NEGATIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION	BP	MYC
GO_CHROMATIN_REMODELING	BP	MYC
GO_BETA_CATENIN_TCF_COMPLEX_ASSEMBLY	BP	MYC
GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION	BP	MYC
GO_POSITIVE_REGULATION_OF_STEM_CELL_PROLIFERATION	BP	MYC
GO_NEPHRON_DEVELOPMENT	BP	MYC
GO_REGULATION_OF_GLIOGENESIS	BP	MYC
GO_PHOSPHORYLATION	BP	MYC
GO_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE	BP	MYC
GO_MESONEPHROS_DEVELOPMENT	BP	MYC
GO_SKELETAL_SYSTEM_MORPHOGENESIS	BP	MYC
GO_CELLULAR_RESPONSE_TO_DRUG	BP	MYC
GO_IRON_ION_HOMEOSTASIS	BP	MYC
GO_NUCLEOLUS	CC	MYC
GO_E_BOX_BINDING	MF	MYC
GO_REPRESSING_TRANSCRIPTION_FACTOR_BINDING	MF	MYC
GO_TRANSCRIPTION_COACTIVATOR_ACTIVITY	MF	MYC

Survival analysis of MYC

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of MYC

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)