Sample overview of BT-549

Sample ID: Sample_02_395
Biosample type: Cell line
Tissue type: Mammary Gland
Biosample name: BT-549
Data source: NCBI GEO/SRA
GSE ID: GSE65201
Cancer type: basal-like breast cancer
CRC number: 3575
TF number of all CRCs: 54
TF list of all CRCs: SMAD3, RARA, HOXC11, EN1, HOXC10, TFAP2A, FOXC1, RUNX1, JUNB, MAFF, SOX4, ETS1, HOXB8, BCL6, NR2F2, MAZ, TGIF1, IRX5, MEF2D, IRF1, SREBF1, HOXC4, HOXC9, BHLHE40, NFIB, MYC, ZBTB7B, HOXB4, HOXB3, JUN, KLF16, HOXB5, FOSL1, EOMES, NFIX, HOXC8, HES1, E2F3, CEBPB, NR3C1, HOXB7, FOSL2, KLF7, STAT6, SNAI2, ZNF217, HOXB2, OTX1, MNT, ZIC2, ZEB1, HOXB6, ERF, TBX18

The most representative CRC of BT-549
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Relationship plot of CRC model
TF number of this CRC: 14
CRC socre: 2081.643
TF list of the most representative CRC
TF name TF family Frequency of TFs
BHLHE40 bHLH 977 / 3575
EN1 Homeobox 3128 / 3575
ETS1 ETS 1417 / 3575
HOXB8 Homeobox 1394 / 3575
HOXC10 Homeobox 2940 / 3575
HOXC11 Homeobox 3215 / 3575
HOXC4 Homeobox 1046 / 3575
JUNB TF_bZIP 1424 / 3575
KLF16 zf-C2H2 746 / 3575
MAFF TF_bZIP 1423 / 3575
RARA THR-like 3575 / 3575
RUNX1 Runt 1832 / 3575
SMAD3 MH1 3575 / 3575
TFAP2A AP-2 2451 / 3575

All CRCs of BT-549
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
RARA 3575 / 3575 THR-like ENSG00000131759
SMAD3 3575 / 3575 MH1 ENSG00000166949
HOXC11 3215 / 3575 Homeobox ENSG00000123388
EN1 3128 / 3575 Homeobox ENSG00000163064
HOXC10 2940 / 3575 Homeobox ENSG00000180818
TFAP2A 2451 / 3575 AP-2 ENSG00000137203
FOXC1 1874 / 3575 Fork_head ENSG00000054598
RUNX1 1832 / 3575 Runt ENSG00000159216
JUNB 1424 / 3575 TF_bZIP ENSG00000171223
MAFF 1423 / 3575 TF_bZIP ENSG00000185022
SOX4 1418 / 3575 HMG ENSG00000124766
ETS1 1417 / 3575 ETS ENSG00000134954
HOXB8 1394 / 3575 Homeobox ENSG00000120068
BCL6 1392 / 3575 ZBTB ENSG00000113916
NR2F2 1351 / 3575 RXR-like ENSG00000185551
MAZ 1286 / 3575 zf-C2H2 ENSG00000103495
TGIF1 1188 / 3575 Homeobox ENSG00000177426
IRX5 1155 / 3575 Homeobox ENSG00000176842
MEF2D 1085 / 3575 SRF ENSG00000116604
IRF1 1068 / 3575 IRF ENSG00000125347
SREBF1 1055 / 3575 bHLH ENSG00000072310
HOXC4 1046 / 3575 Homeobox ENSG00000198353
HOXC9 1017 / 3575 Homeobox ENSG00000180806
BHLHE40 977 / 3575 bHLH ENSG00000134107
NFIB 963 / 3575 CTF/NFI ENSG00000147862
MYC 934 / 3575 bHLH ENSG00000136997
ZBTB7B 921 / 3575 ZBTB ENSG00000160685
HOXB4 805 / 3575 Homeobox ENSG00000182742
HOXB3 772 / 3575 Homeobox ENSG00000120093
JUN 754 / 3575 TF_bZIP ENSG00000177606
KLF16 746 / 3575 zf-C2H2 ENSG00000129911
HOXB5 699 / 3575 Homeobox ENSG00000120075
FOSL1 686 / 3575 TF_bZIP ENSG00000175592
EOMES 597 / 3575 T-box ENSG00000163508
NFIX 594 / 3575 CTF/NFI ENSG00000008441
HOXC8 549 / 3575 Homeobox ENSG00000037965
HES1 546 / 3575 bHLH ENSG00000114315
E2F3 467 / 3575 E2F ENSG00000112242
CEBPB 437 / 3575 TF_bZIP ENSG00000172216
NR3C1 430 / 3575 ESR-like ENSG00000113580
HOXB7 422 / 3575 Homeobox ENSG00000260027
FOSL2 419 / 3575 TF_bZIP ENSG00000075426
KLF7 352 / 3575 zf-C2H2 ENSG00000118263
STAT6 351 / 3575 STAT ENSG00000166888
SNAI2 341 / 3575 zf-C2H2 ENSG00000019549
ZNF217 336 / 3575 zf-C2H2 ENSG00000171940
HOXB2 240 / 3575 Homeobox ENSG00000173917
OTX1 221 / 3575 TF_Otx ENSG00000115507
MNT 185 / 3575 bHLH ENSG00000070444
ZIC2 173 / 3575 zf-C2H2 ENSG00000043355
ZEB1 144 / 3575 zf-C2H2 ENSG00000148516
HOXB6 113 / 3575 Homeobox ENSG00000108511
ERF 67 / 3575 ETS ENSG00000105722
TBX18 24 / 3575 T-box ENSG00000112837

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
MNT 60 54 114
MAFF 54 87 141
RARA 67 102 169
KLF7 40 95 135
BHLHE40 61 78 139
IRX5 61 84 145
MYC 62 84 146
SNAI2 56 84 140
MAZ 58 101 159
RUNX1 65 100 165
HOXC9 67 83 150
HOXC8 67 62 129
NR3C1 51 99 150
OTX1 52 84 136
EN1 68 90 158
ZIC2 47 90 137
HOXB8 67 77 144
HOXB2 65 59 124
HOXB3 67 73 140
HOXB6 67 57 124
HOXB7 67 59 126
HOXB4 67 66 133
HOXB5 67 67 134
HOXC10 67 96 163
ZEB1 37 99 136
HOXC11 67 90 157
IRF1 55 101 156
MEF2D 51 85 136
HES1 59 76 135
FOXC1 58 101 159
ZNF217 68 55 123
SMAD3 66 102 168
STAT6 48 97 145
NR2F2 65 84 149
FOSL1 53 89 142
FOSL2 60 74 134
TBX18 39 66 105
SREBF1 61 91 152
JUNB 63 84 147
ERF 48 67 115
SOX4 56 99 155
CEBPB 56 72 128
KLF16 54 92 146
TFAP2A 65 102 167
EOMES 53 97 150
ETS1 56 98 154
HOXC4 67 64 131
ZBTB7B 63 82 145
JUN 48 92 140
NFIB 67 67 134
NFIX 68 65 133
E2F3 46 99 145
BCL6 60 101 161
TGIF1 61 86 147

Expression of TFs in all CRCs