Cancer CRCdb

TF information

TF name:	STAT6
TF family:	STAT
Ensembl gene ID:	ENSG00000166888
Ensembl protein ID:	ENSP00000438451, ENSP00000401486, ENSP00000444530, ENSP00000445409, ENSP00000451742, ENSP00000491116, ENSP00000451546, ENSP00000450921, ENSP00000300134
Entrez gene ID:	6778

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of STAT6 in all biosamples

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Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_164	Cell line	Lung	H2087_Parental	0.55
Sample_02_228	Cell line	Oesophagus	KYSE510	0.40074557315937
Sample_02_237	Cell line	Colon	V389	0.23567090005522
Sample_02_242	Cell line	Colon	V481	0.021726591040185
Sample_02_304	Cell line	Neuroblastoma	N206	0.40217391304348
Sample_02_313	Cell line	Neuroblastoma	SK-N-DZ	0.41312741312741
Sample_02_395	Cell line	Mammary Gland	BT-549	0.098181818181818

STAT6 distribution in samples’ most representative CRC

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Sample ID	Tissue type	Biosample type	Biosample name
Sample_02_164	Lung	Cell line	H2087_Parental
Sample_02_304	Neuroblastoma	Cell line	N206
Sample_02_313	Neuroblastoma	Cell line	SK-N-DZ

STAT6 distribution in all CRCs

Genomic distribution of SEs associated with STAT6

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Mutation of STAT6

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Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of STAT6

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr12	57498946	57498946	G	T	exonic	STAT6	nonsynonymous	UCEC\|1\|248\|0.00403
rs757010323	chr12	57499302	57499302	C	T	exonic	STAT6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr12	57493118	57493118	G	A	exonic	STAT6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr12	57492845	57492845	C	A	exonic	STAT6	nonsynonymous	ESCA\|1\|185\|0.00541
rs757430778	chr12	57501513	57501513	C	T	exonic	STAT6	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189,UCEC\|1\|248\|0.00403
-	chr12	57496628	57496628	T	C	exonic	STAT6	nonsynonymous	OV\|1\|469\|0.00213
-	chr12	57499001	57499001	T	A	exonic	STAT6	nonsynonymous	CHOL\|1\|35\|0.02857
-	chr12	57499092	57499092	C	A	exonic	STAT6	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs776930978	chr12	57496186	57496186	G	A	exonic	STAT6	nonsynonymous	SKCM\|1\|368\|0.00272
rs766446465	chr12	57493798	57493798	G	A	exonic	STAT6	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr12	57498314	57498314	T	C	exonic	STAT6	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr12	57501019	57501037	CCATAACAGCTTTTTTCTC	-	exonic	STAT6	frameshift	OV\|1\|469\|0.00213
rs201779891	chr12	57493656	57493656	G	A	exonic	STAT6	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr12	57492807	57492807	G	A	exonic	STAT6	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr12	57501400	57501400	G	A	exonic	STAT6	synonymous	LUAD\|1\|543\|0.00184
-	chr12	57492642	57492642	C	T	exonic	STAT6	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr12	57500503	57500503	G	T	exonic	STAT6	nonsynonymous	KIPAN\|2\|799\|0.00250,KIRC\|2\|451\|0.00443
-	chr12	57496677	57496677	C	G	exonic	STAT6	nonsynonymous	OV\|1\|469\|0.00213
-	chr12	57496235	57496236	CT	-	exonic	STAT6	frameshift	BLCA\|1\|396\|0.00253
-	chr12	57490363	57490363	T	A	exonic	STAT6	nonsynonymous	THCA\|1\|504\|0.00198
-	chr12	57492859	57492859	C	T	exonic	STAT6	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr12	57500011	57500011	C	T	exonic	STAT6	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr12	57499366	57499366	C	T	exonic	STAT6	nonsynonymous	BLCA\|1\|396\|0.00253
rs766506451	chr12	57493655	57493655	C	T	exonic	STAT6	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr12	57493582	57493582	A	G	exonic	STAT6	nonsynonymous	ACC\|1\|90\|0.01111
-	chr12	57493598	57493598	A	T	exonic	STAT6	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr12	57501063	57501063	G	T	exonic	STAT6	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr12	57498539	57498539	C	G	exonic	STAT6	synonymous	LIHC\|1\|373\|0.00268
-	chr12	57500358	57500358	G	C	exonic	STAT6	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr12	57500358	57500358	G	A	exonic	STAT6	synonymous	BRCA\|1\|982\|0.00102
rs778871413	chr12	57501470	57501470	G	A	exonic	STAT6	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr12	57493106	57493106	T	C	exonic	STAT6	nonsynonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr12	57499106	57499106	T	G	exonic	STAT6	nonsynonymous	THYM\|1\|123\|0.00813
-	chr12	57493192	57493192	G	T	exonic	STAT6	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
rs575257117	chr12	57501482	57501482	C	T	exonic	STAT6	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr12	57499094	57499094	G	-	exonic	STAT6	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|3\|395\|0.00759,STES\|3\|395\|0.00759
rs749244007	chr12	57493155	57493155	G	A	exonic	STAT6	stopgain	CESC\|1\|194\|0.00515,STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr12	57493169	57493169	C	A	exonic	STAT6	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr12	57500334	57500334	C	T	exonic	STAT6	nonsynonymous	UCEC\|1\|248\|0.00403
rs754583855	chr12	57499025	57499025	C	T	exonic	STAT6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr12	57501038	57501038	T	A	exonic	STAT6	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs749654830	chr12	57490454	57490454	-	C	exonic	STAT6	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr12	57499083	57499083	C	T	exonic	STAT6	synonymous	BRCA\|1\|982\|0.00102
-	chr12	57496654	57496654	A	T	exonic	STAT6	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr12	57499025	57499025	C	-	exonic	STAT6	frameshift	LIHC\|1\|373\|0.00268
-	chr12	57493858	57493858	G	A	exonic	STAT6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr12	57493638	57493638	G	A	exonic	STAT6	synonymous	BRCA\|1\|982\|0.00102
-	chr12	57492825	57492825	G	A	exonic	STAT6	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr12	57490680	57490680	T	A	exonic	STAT6	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs773945763	chr12	57490386	57490386	T	G	exonic	STAT6	nonsynonymous	UCEC\|1\|248\|0.00403
rs776641789	chr12	57500552	57500552	C	A	exonic	STAT6	nonsynonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
rs777634893	chr12	57499054	57499054	C	T	exonic	STAT6	nonsynonymous	PRAD\|2\|499\|0.00401
-	chr12	57490477	57490477	C	T	exonic	STAT6	nonsynonymous	CESC\|1\|194\|0.00515
-	chr12	57493818	57493818	T	C	exonic	STAT6	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr12	57492326	57492326	G	A	exonic	STAT6	synonymous	SKCM\|1\|368\|0.00272
-	chr12	57496103	57496103	G	A	exonic	STAT6	synonymous	SKCM\|2\|368\|0.00543
-	chr12	57493835	57493835	C	A	exonic	STAT6	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr12	57500318	57500318	G	A	exonic	STAT6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr12	57500498	57500498	C	G	exonic	STAT6	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr12	57498569	57498569	G	T	exonic	STAT6	nonsynonymous	CHOL\|1\|35\|0.02857
-	chr12	57496631	57496631	T	C	exonic	STAT6	nonsynonymous	PRAD\|1\|499\|0.00200
rs751205671	chr12	57493091	57493091	C	T	exonic	STAT6	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr12	57493815	57493815	A	G	exonic	STAT6	nonsynonymous	TGCT\|1\|155\|0.00645
-	chr12	57492632	57492632	T	C	exonic	STAT6	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr12	57490531	57490531	T	A	exonic	STAT6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr12	57490455	57490455	C	-	exonic	STAT6	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs749019797	chr12	57496109	57496109	G	A	exonic	STAT6	synonymous	BRCA\|1\|982\|0.00102
-	chr12	57502002	57502002	G	C	exonic	STAT6	synonymous	SKCM\|1\|368\|0.00272
-	chr12	57496615	57496615	C	G	exonic	STAT6	nonsynonymous	HNSC\|1\|512\|0.00195
rs759277693	chr12	57499020	57499020	-	G	exonic	STAT6	frameshift	KIPAN\|2\|799\|0.00250,KIRC\|2\|451\|0.00443
rs780257871	chr12	57501507	57501507	C	T	exonic	STAT6	nonsynonymous	OV\|1\|469\|0.00213
-	chr12	57498953	57498953	G	A	exonic	STAT6	stopgain	BRCA\|1\|982\|0.00102
-	chr12	57501992	57501992	G	A	exonic	STAT6	stopgain	SKCM\|1\|368\|0.00272
-	chr12	57492339	57492339	T	A	exonic	STAT6	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr12	57496082	57496082	C	A	exonic	STAT6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr12	57490408	57490408	G	A	exonic	STAT6	stopgain	UCEC\|1\|248\|0.00403
-	chr12	57490895	57490895	G	-	exonic	STAT6	frameshift	ESCA\|1\|185\|0.00541
-	chr12	57498293	57498293	G	T	exonic	STAT6	nonsynonymous	BRCA\|1\|982\|0.00102
rs768675729	chr12	57499332	57499332	G	A	exonic	STAT6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs750313035	chr12	57499303	57499303	G	A	exonic	STAT6	nonsynonymous	PAAD\|1\|185\|0.00541
rs767265892	chr12	57501443	57501443	G	A	exonic	STAT6	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr12	57499063	57499063	G	A	exonic	STAT6	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr12	57498342	57498342	G	C	exonic	STAT6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr12	57501489	57501489	A	C	exonic	STAT6	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr12	57499068	57499068	G	A	exonic	STAT6	synonymous	SKCM\|1\|368\|0.00272
-	chr12	57499067	57499067	G	A	exonic	STAT6	stopgain	SKCM\|1\|368\|0.00272
rs12314983	chr12	57492308	57492308	G	A	exonic	STAT6	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs772021515	chr12	57501993	57501993	G	A	exonic	STAT6	synonymous	LUAD\|1\|543\|0.00184
-	chr12	57493220	57493220	G	A	exonic	STAT6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr12	57501977	57501977	G	A	exonic	STAT6	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr12	57502041	57502041	G	A	exonic	STAT6	synonymous	OV\|1\|469\|0.00213
-	chr12	57493104	57493104	C	A	exonic	STAT6	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr12	57496658	57496658	T	C	exonic	STAT6	nonsynonymous	DLBC\|1\|48\|0.02083
rs559027154	chr12	57499295	57499295	C	T	exonic	STAT6	synonymous	PAAD\|1\|185\|0.00541,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs866152566	chr12	57492348	57492348	A	G	exonic	STAT6	nonsynonymous	HNSC\|2\|512\|0.00391,SKCM\|1\|368\|0.00272
-	chr12	57490672	57490672	C	T	exonic	STAT6	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122,HNSC\|2\|512\|0.00391
-	chr12	57498306	57498306	C	T	exonic	STAT6	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr12	57501056	57501056	G	C	exonic	STAT6	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr12	57500575	57500575	C	A	exonic	STAT6	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr12	57490852	57490852	G	A	exonic	STAT6	stopgain	BLCA\|1\|396\|0.00253
-	chr12	57492635	57492635	G	C	exonic	STAT6	nonsynonymous	CESC\|1\|194\|0.00515
-	chr12	57492328	57492328	A	G	exonic	STAT6	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr12	57501478	57501478	G	A	exonic	STAT6	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs767674545	chr12	57499093	57499093	-	G	exonic	STAT6	frameshift	BRCA\|2\|982\|0.00204,KIPAN\|6\|799\|0.00751,KIRC\|6\|451\|0.01330,LUAD\|1\|543\|0.00184,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs762223545	chr12	57499264	57499264	T	C	exonic	STAT6	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr12	57498535	57498535	A	G	exonic	STAT6	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
rs188884452	chr12	57502012	57502012	C	T	exonic	STAT6	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr12	57499326	57499326	C	T	exonic	STAT6	nonsynonymous	BRCA\|2\|982\|0.00204
-	chr12	57499293	57499293	A	T	exonic	STAT6	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr12	57501096	57501096	C	T	exonic	STAT6	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr12	57490445	57490445	C	G	exonic	STAT6	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr12	57492848	57492848	A	C	exonic	STAT6	synonymous	BRCA\|1\|982\|0.00102

Disease information of STAT6

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TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
STAT6	Dermatitis, Atopic	C16;C17;C20	Disease or Syndrome	CTD_human
STAT6	Edema	C23	Sign or Symptom	CTD_human
STAT6	Head and Neck Neoplasms	C04	Neoplastic Process	CTD_human
STAT6	Head Neoplasms	C04	Neoplastic Process	CTD_human
STAT6	hemangiopericytoma	C04	Neoplastic Process	ORPHANET
STAT6	Neck Neoplasms	C04	Neoplastic Process	CTD_human
STAT6	Pulmonary Fibrosis	C08	Disease or Syndrome	CTD_human
STAT6	Diffuse Large B-Cell Lymphoma	C04;C15;C20	Neoplastic Process	CGI
STAT6	Hamman-Rich syndrome	C08	Disease or Syndrome	CTD_human
STAT6	Eczema, Infantile	C16;C17;C20	Disease or Syndrome	CTD_human
STAT6	Anasarca	C23	Pathologic Function	CTD_human
STAT6	Malignant Head and Neck Neoplasm	C04	Neoplastic Process	CTD_human
STAT6	Cancer of Neck	C04	Neoplastic Process	CTD_human
STAT6	Cancer of Head	C04	Neoplastic Process	CTD_human
STAT6	Upper Aerodigestive Tract Neoplasms	C04	Neoplastic Process	CTD_human
STAT6	Solitary fibrous tumor	C04	Neoplastic Process	CTD_human;ORPHANET

Pathway associated with STAT6

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pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0000633	Downstream signal transduction	reactome	29	307
pathway0000899	Gene expression of SOCS by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram )	inoh	14	66
pathway0000900	Gene expression of SOCS1 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram )	inoh	8	29
pathway0000901	Gene expression of SOCS3 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram )	inoh	8	29
pathway0001104	IL-13 signaling pathway(JAK1 TYK2 STAT6) ( IL-13 signaling(JAK1 TYK2 STAT6) )	inoh	10	45
pathway0001108	IL-4 signaling pathway(JAK1 JAK3 STAT6) ( IL-4 signaling(JAK1 JAK3 STAT6) )	inoh	7	23
pathway0001135	IL9	netpath	24	200
pathway0001228	JAK/STAT signaling pathway	panther	15	87
pathway0002040	Signaling events mediated by TCPTP	pid	40	361
pathway0002355	TSLP	netpath	24	159
pathway0002686	Hs_Tryptophan_metabolism_WP465_85055	wikipathways	45	103
pathway0002689	Hs_Cytokines_and_Inflammatory_Response_WP530_79331	wikipathways	21	53
pathway0002758	Hs_TGF-beta_Receptor_Signaling_WP560_90187	wikipathways	28	32
pathway0002840	Hs_G1_to_S_cell_cycle_control_WP45_80001	wikipathways	8	21
pathway0002864	Hs_IL-4_Signaling_Pathway_WP395_89828	wikipathways	41	397

Go term information of STAT6

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GO_term_name	GO_term_type	TF_name
GO_REGULATION_OF_DNA_RECOMBINATION	BP	STAT6
GO_MAMMARY_GLAND_MORPHOGENESIS	BP	STAT6
GO_POSITIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE	BP	STAT6
GO_GLAND_MORPHOGENESIS	BP	STAT6
GO_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION	BP	STAT6
GO_RESPONSE_TO_INTERLEUKIN_4	BP	STAT6
GO_ALPHA_BETA_T_CELL_DIFFERENTIATION	BP	STAT6
GO_MAMMARY_GLAND_EPITHELIUM_DEVELOPMENT	BP	STAT6
GO_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE	BP	STAT6
GO_POSITIVE_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY	BP	STAT6
GO_LEUKOCYTE_DIFFERENTIATION	BP	STAT6
GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_4	BP	STAT6
GO_NEGATIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE	BP	STAT6
GO_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION	BP	STAT6
GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	BP	STAT6
GO_T_HELPER_1_TYPE_IMMUNE_RESPONSE	BP	STAT6
GO_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE	BP	STAT6
GO_CELLULAR_RESPONSE_TO_HYDROGEN_PEROXIDE	BP	STAT6
GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY	BP	STAT6
GO_ORGAN_MORPHOGENESIS	BP	STAT6
GO_POSITIVE_T_CELL_SELECTION	BP	STAT6
GO_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY	BP	STAT6
GO_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY	BP	STAT6
GO_POSITIVE_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION	BP	STAT6
GO_ADAPTIVE_IMMUNE_RESPONSE	BP	STAT6
GO_CD4_POSITIVE_OR_CD8_POSITIVE_ALPHA_BETA_T_CELL_LINEAGE_COMMITMENT	BP	STAT6
GO_REGULATION_OF_ISOTYPE_SWITCHING	BP	STAT6
GO_ALPHA_BETA_T_CELL_ACTIVATION	BP	STAT6
GO_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE	BP	STAT6
GO_T_CELL_LINEAGE_COMMITMENT	BP	STAT6
GO_POSITIVE_REGULATION_OF_DNA_RECOMBINATION	BP	STAT6
GO_EPITHELIAL_CELL_PROLIFERATION	BP	STAT6
GO_MAMMARY_GLAND_EPITHELIAL_CELL_PROLIFERATION	BP	STAT6
GO_CELLULAR_RESPONSE_TO_REACTIVE_NITROGEN_SPECIES	BP	STAT6
GO_POSITIVE_REGULATION_OF_B_CELL_ACTIVATION	BP	STAT6
GO_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES	BP	STAT6
GO_RESPONSE_TO_HYDROGEN_PEROXIDE	BP	STAT6
GO_T_CELL_SELECTION	BP	STAT6
GO_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE	BP	STAT6
GO_MEMBRANE_MICRODOMAIN	CC	STAT6
GO_CORE_PROMOTER_BINDING	MF	STAT6
GO_NUCLEIC_ACID_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY	MF	STAT6
GO_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING	MF	STAT6
GO_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING	MF	STAT6

Survival analysis of STAT6

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of STAT6

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)