TF information

TF name: HOXB4
TF family: Homeobox
Ensembl gene ID: ENSG00000182742
Ensembl protein ID: ENSP00000328928
Entrez gene ID: 3214
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of HOXB4 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_021Cell lineColonV4290.078120495820121
Sample_02_078Primary cellNeuroblastomalow-MYCN-Neuroblastoma-patient-cells0.25
Sample_02_114Cell lineMammary GlandCAL510.22613065326633
Sample_02_268Cell lineKidneyA-4980.029167435850102
Sample_02_355Cell lineColonHCT150.45238095238095
Sample_02_356Cell lineColonSw4800.13548387096774
Sample_02_358Cell lineColonLS1800.3349131121643
Sample_02_395Cell lineMammary GlandBT-5490.22517482517483
Sample_02_424Cell lineColonSW6200.057971014492754

HOXB4 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_355ColonCell lineHCT15

HOXB4 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with HOXB4
Download

Mutation of HOXB4
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of HOXB4

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr174665416846654168GCexonicHOXB4synonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr174665523246655232CTexonicHOXB4synonymous CESC|1|194|0.00515
-chr174665429646654296GAexonicHOXB4nonsynonymous SKCM|2|368|0.00543
-chr174665562146655621CGexonicHOXB4nonsynonymous BRCA|1|982|0.00102
-chr174665526446655264CTexonicHOXB4nonsynonymous PRAD|1|499|0.00200
-chr174665526346655263AGexonicHOXB4nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr174665538746655387CTexonicHOXB4nonsynonymous PRAD|1|499|0.00200
-chr174665415546654155GAexonicHOXB4nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr174665411846654118GTexonicHOXB4nonsynonymous LUAD|1|543|0.00184
-chr174665532846655328CTexonicHOXB4synonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr174665421546654215ACexonicHOXB4nonsynonymous CESC|1|194|0.00515
-chr174665433046654330CTexonicHOXB4synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr174665532646655326GTexonicHOXB4nonsynonymous LUAD|1|543|0.00184
-chr174665415446654154CTexonicHOXB4nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr174665411046654110GAexonicHOXB4nonsynonymous BLCA|2|396|0.00505
-chr174665527946655279CTexonicHOXB4nonsynonymous OV|1|469|0.00213
-chr174665539346655393GAexonicHOXB4nonsynonymous LIHC|1|373|0.00268
-chr174665426046654260CGexonicHOXB4nonsynonymous BLCA|1|396|0.00253
-chr174665559446655594GAexonicHOXB4nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs767904414chr174665411346654113GTexonicHOXB4synonymous LUAD|1|543|0.00184
-chr174665409246654092CTexonicHOXB4nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr174665412546654125CTexonicHOXB4nonsynonymous LUAD|1|543|0.00184
-chr174665434746654347ACexonicHOXB4nonsynonymous BLCA|1|396|0.00253
rs774903494chr174665422246654222GCexonicHOXB4nonsynonymous HNSC|1|512|0.00195
-chr174665416846654168G-exonicHOXB4frameshift LUAD|1|543|0.00184
-chr174665571546655715ACUTR5HOXB4unknown BLCA|1|396|0.00253
-chr174665528546655285G-exonicHOXB4frameshift LIHC|1|373|0.00268
-chr174665434646654346GTexonicHOXB4nonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr174665419546654195CAexonicHOXB4nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr174665526546655265GAexonicHOXB4synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr174665545246655452GTexonicHOXB4nonsynonymous TGCT|1|155|0.00645
-chr174665433446654334TAexonicHOXB4nonsynonymous KICH|1|66|0.01515,KIPAN|1|799|0.00125
-chr174665563346655633-TTexonicHOXB4frameshift KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr174665532546655325CTexonicHOXB4synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr174665435546654355GTexonicHOXB4nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr174665419646654196ATexonicHOXB4nonsynonymous LUAD|1|543|0.00184
-chr174665417146654171CAexonicHOXB4nonsynonymous BLCA|2|396|0.00505
-chr174665530746655307GAexonicHOXB4synonymous SKCM|1|368|0.00272
rs764769248chr174665523546655235GAexonicHOXB4synonymous TGCT|1|155|0.00645
-chr174665560746655607CAexonicHOXB4nonsynonymous BRCA|1|982|0.00102
rs773856875chr174665560346655603CTexonicHOXB4nonsynonymous HNSC|1|512|0.00195

Disease information of HOXB4
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source

Pathway associated with HOXB4
pathway_ID pathway_name pathway_source gene_number edge_number

Go term information of HOXB4
GO_term_name GO_term_type TF_name
GO_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS BP HOXB4
GO_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION BP HOXB4
GO_STEM_CELL_DIVISION BP HOXB4
GO_MORPHOGENESIS_OF_AN_EPITHELIAL_SHEET BP HOXB4
GO_SOMATIC_STEM_CELL_DIVISION BP HOXB4
GO_DEFINITIVE_HEMOPOIESIS BP HOXB4
GO_EMBRYONIC_ORGAN_DEVELOPMENT BP HOXB4
GO_SPLEEN_DEVELOPMENT BP HOXB4

Survival analysis of HOXB4



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of HOXB4