Sample overview of Sw480

Sample ID: Sample_02_356
Biosample type: Cell line
Tissue type: Colon
Biosample name: Sw480
Data source: NCBI GEO/SRA
GSE ID: GSE73319
Cancer type: Colorectal Cancer
CRC number: 155
TF number of all CRCs: 33
TF list of all CRCs: RARA, HOXA10, HOXA7, FOS, HOXA9, NFATC2, SMAD3, FOXQ1, HOXB3, SOX13, RUNX1, HOXB8, ETV4, RREB1, TGIF1, SREBF1, HOXB5, BHLHE40, MAFK, HOXB6, MYC, ETV6, ERF, MNT, ZNF628, ETV3, HES1, HOXB7, HOXB4, ZBTB7A, DLX2, FOSL2, FOSL1

The most representative CRC of Sw480
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Relationship plot of CRC model
TF number of this CRC: 8
CRC socre: 94.5
TF list of the most representative CRC
TF name TF family Frequency of TFs
ETV4 ETS 66 / 155
FOS TF_bZIP 107 / 155
HOXA10 Homeobox 142 / 155
HOXA7 Homeobox 110 / 155
HOXA9 Homeobox 100 / 155
MAFK TF_bZIP 47 / 155
MNT bHLH 29 / 155
RARA THR-like 155 / 155

All CRCs of Sw480
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
RARA 155 / 155 THR-like ENSG00000131759
HOXA10 142 / 155 Homeobox ENSG00000253293
HOXA7 110 / 155 Homeobox ENSG00000122592
FOS 107 / 155 TF_bZIP ENSG00000170345
HOXA9 100 / 155 Homeobox ENSG00000078399
NFATC2 99 / 155 RHD ENSG00000101096
SMAD3 95 / 155 MH1 ENSG00000166949
FOXQ1 89 / 155 Fork_head ENSG00000164379
HOXB3 88 / 155 Homeobox ENSG00000120093
RUNX1 76 / 155 Runt ENSG00000159216
SOX13 76 / 155 HMG ENSG00000143842
HOXB8 67 / 155 Homeobox ENSG00000120068
ETV4 66 / 155 ETS ENSG00000175832
RREB1 65 / 155 zf-C2H2 ENSG00000124782
TGIF1 63 / 155 Homeobox ENSG00000177426
SREBF1 54 / 155 bHLH ENSG00000072310
HOXB5 51 / 155 Homeobox ENSG00000120075
BHLHE40 50 / 155 bHLH ENSG00000134107
MAFK 47 / 155 TF_bZIP ENSG00000198517
HOXB6 44 / 155 Homeobox ENSG00000108511
MYC 43 / 155 bHLH ENSG00000136997
ERF 39 / 155 ETS ENSG00000105722
ETV6 39 / 155 ETS ENSG00000139083
MNT 29 / 155 bHLH ENSG00000070444
ZNF628 29 / 155 zf-C2H2 ENSG00000197483
ETV3 26 / 155 ETS ENSG00000117036
HES1 25 / 155 bHLH ENSG00000114315
HOXB7 22 / 155 Homeobox ENSG00000260027
HOXB4 21 / 155 Homeobox ENSG00000182742
ZBTB7A 20 / 155 ZBTB ENSG00000178951
DLX2 18 / 155 Homeobox ENSG00000115844
FOSL2 13 / 155 TF_bZIP ENSG00000075426
FOSL1 2 / 155 TF_bZIP ENSG00000175592

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
NFATC2 32 47 79
SMAD3 31 49 80
ERF 29 44 73
MAFK 25 50 75
HOXA10 34 49 83
RREB1 29 49 78
RARA 34 49 83
ZNF628 29 35 64
SOX13 32 47 79
MNT 33 28 61
RUNX1 31 50 81
FOSL1 12 49 61
FOSL2 31 39 70
MYC 32 44 76
DLX2 28 39 67
FOXQ1 31 46 77
HOXB8 34 42 76
ZBTB7A 32 27 59
FOS 32 48 80
HOXB3 34 43 77
HOXB6 34 35 69
HOXB4 34 35 69
HOXB5 34 38 72
HOXB7 34 35 69
ETV3 31 40 71
ETV4 30 50 80
ETV6 26 49 75
HOXA7 34 46 80
BHLHE40 33 37 70
SREBF1 30 44 74
TGIF1 29 49 78
HES1 31 38 69
HOXA9 34 48 82

Expression of TFs in all CRCs