TF information

TF name: HOXA7
TF family: Homeobox
Ensembl gene ID: ENSG00000122592
Ensembl protein ID: ENSP00000242159
Entrez gene ID: 3204
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of HOXA7 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_021Cell lineColonV4290.21331795906601
Sample_02_029Cell lineColorectalLS174T0.5
Sample_02_069Cell lineBrainSF2680.49618320610687
Sample_02_114Cell lineMammary GlandCAL510.91457286432161
Sample_02_268Cell lineKidneyA-4980.0084917851209156
Sample_02_356Cell lineColonSw4800.70967741935484
Sample_02_358Cell lineColonLS1800.86769352290679
Sample_02_424Cell lineColonSW6200.36231884057971

HOXA7 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_029ColorectalCell lineLS174T
Sample_02_114Mammary GlandCell lineCAL51
Sample_02_356ColonCell lineSw480
Sample_02_358ColonCell lineLS180

HOXA7 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with HOXA7
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Mutation of HOXA7
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of HOXA7

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr72719600927196009CGexonicHOXA7synonymous LUAD|1|543|0.00184
-chr72719602927196029CGexonicHOXA7nonsynonymous LUAD|6|543|0.01105
-chr72719591927195919GAexonicHOXA7synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr72719463427194634GAexonicHOXA7nonsynonymous UCEC|1|248|0.00403
rs529254085chr72719593827195938GAexonicHOXA7nonsynonymous SKCM|1|368|0.00272
rs765294385chr72719605027196050CTexonicHOXA7nonsynonymous LUAD|1|543|0.00184
-chr72719484127194841CTexonicHOXA7nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
rs200468253chr72719462027194620CTexonicHOXA7nonsynonymous BLCA|1|396|0.00253
-chr72719480727194807CGexonicHOXA7synonymous LUAD|1|543|0.00184
-chr72719454727194547TCexonicHOXA7nonsynonymous LIHC|1|373|0.00268
-chr72719472327194723CTexonicHOXA7synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr72719616227196162CTexonicHOXA7nonsynonymous HNSC|1|512|0.00195
-chr72719471927194719ACexonicHOXA7nonsynonymous LIHC|1|373|0.00268
-chr72719483027194830TGexonicHOXA7nonsynonymous LUAD|1|543|0.00184
-chr72719597227195972GTexonicHOXA7nonsynonymous LUAD|1|543|0.00184
-chr72719477327194773GAexonicHOXA7nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr72719467627194676CTexonicHOXA7nonsynonymous UCEC|1|248|0.00403
rs201959803chr72719474027194740TCexonicHOXA7nonsynonymous LUAD|1|543|0.00184
-chr72719464827194648GAexonicHOXA7synonymous LUAD|1|543|0.00184
-chr72719599627195996CTexonicHOXA7nonsynonymous UCEC|1|248|0.00403
rs78410337chr72719611627196116CTexonicHOXA7nonsynonymous DLBC|1|48|0.02083
rs766259696chr72719593227195932CTexonicHOXA7nonsynonymous UCEC|1|248|0.00403
rs770523270chr72719464727194647CTexonicHOXA7nonsynonymous HNSC|1|512|0.00195,SKCM|1|368|0.00272
rs755438662chr72719607627196076GAexonicHOXA7nonsynonymous CESC|1|194|0.00515
rs750774350chr72719601927196019GAexonicHOXA7nonsynonymous BLCA|1|396|0.00253
-chr72719602927196029CTexonicHOXA7nonsynonymous PAAD|1|185|0.00541
-chr72719613827196138CTexonicHOXA7synonymous UCEC|1|248|0.00403
-chr72719469527194695TGexonicHOXA7nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr72719472427194724GAexonicHOXA7nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr72719478427194784TCexonicHOXA7nonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr72719594227195942CTexonicHOXA7nonsynonymous LUSC|1|178|0.00562
-chr72719466327194663CAexonicHOXA7nonsynonymous UCEC|1|248|0.00403
-chr72719474527194745CAexonicHOXA7nonsynonymous LUSC|1|178|0.00562
-chr72719456327194564CC-exonicHOXA7frameshift COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr72719603527196035CTexonicHOXA7nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr72719607927196079CGexonicHOXA7nonsynonymous BLCA|1|396|0.00253
-chr72719594627195946GCexonicHOXA7synonymous LIHC|1|373|0.00268
-chr72719595427195954CTexonicHOXA7nonsynonymous HNSC|1|512|0.00195
rs559344881chr72719475427194754GAexonicHOXA7nonsynonymous STAD|2|395|0.00506,STES|2|395|0.00506
-chr72719588627195886GAexonicHOXA7synonymous UCEC|1|248|0.00403
-chr72719599327195993TAexonicHOXA7nonsynonymous BLCA|1|396|0.00253
rs750200293chr72719591927195919GTexonicHOXA7stopgain UCEC|1|248|0.00403
rs150261196chr72719471427194714GAexonicHOXA7synonymous CESC|1|194|0.00515
-chr72719463227194632CTexonicHOXA7nonsynonymous LUAD|1|543|0.00184
-chr72719612027196120CAexonicHOXA7synonymous LIHC|1|373|0.00268
-chr72719590027195900T-exonicHOXA7frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr72719603927196039CTexonicHOXA7synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr72719596227195962GAexonicHOXA7nonsynonymous BLCA|1|396|0.00253
-chr72719467127194671TCexonicHOXA7nonsynonymous UCEC|1|248|0.00403
-chr72719597227195972GAexonicHOXA7nonsynonymous UCEC|1|248|0.00403
-chr72719586527195865GTexonicHOXA7synonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs370998918chr72719458327194583GAexonicHOXA7nonsynonymous PAAD|1|185|0.00541
-chr72719474227194742CTexonicHOXA7nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs866074728chr72719607027196070GAexonicHOXA7nonsynonymous HNSC|1|512|0.00195
rs780389627chr72719470727194707GAexonicHOXA7nonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355

Disease information of HOXA7
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source

Pathway associated with HOXA7
pathway_ID pathway_name pathway_source gene_number edge_number

Go term information of HOXA7
GO_term_name GO_term_type TF_name
GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING BP HOXA7
GO_REGULATION_OF_EPIDERMIS_DEVELOPMENT BP HOXA7
GO_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS BP HOXA7
GO_REGULATION_OF_LEUKOCYTE_MIGRATION BP HOXA7
GO_NEGATIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION BP HOXA7
GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION BP HOXA7
GO_NEGATIVE_REGULATION_OF_CELL_MATRIX_ADHESION BP HOXA7
GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MIGRATION BP HOXA7
GO_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION BP HOXA7
GO_EMBRYONIC_ORGAN_MORPHOGENESIS BP HOXA7
GO_NEGATIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION BP HOXA7
GO_NEGATIVE_REGULATION_OF_EPIDERMIS_DEVELOPMENT BP HOXA7
GO_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION BP HOXA7
GO_NEGATIVE_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION BP HOXA7
GO_REGULATION_OF_MONOCYTE_DIFFERENTIATION BP HOXA7
GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION BP HOXA7
GO_REGULATION_OF_KERATINOCYTE_DIFFERENTIATION BP HOXA7
GO_REGULATION_OF_CELL_MATRIX_ADHESION BP HOXA7
GO_STEM_CELL_DIFFERENTIATION BP HOXA7
GO_PATTERN_SPECIFICATION_PROCESS BP HOXA7
GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION BP HOXA7
GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING MF HOXA7
GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY_SEQUENCE_SPECIFIC_DNA_BINDING MF HOXA7
GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING MF HOXA7

Survival analysis of HOXA7



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of HOXA7