Cancer CRCdb

TF information

TF name:	ERF
TF family:	ETS
Ensembl gene ID:	ENSG00000105722
Ensembl protein ID:	ENSP00000388173, ENSP00000469274, ENSP00000468962, ENSP00000222329
Entrez gene ID:	2077

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of ERF in all biosamples

Download

Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_069	Cell line	Brain	SF268	0.16030534351145
Sample_02_114	Cell line	Mammary Gland	CAL51	0.040201005025126
Sample_02_115	Cell line	Mammary Gland	MCF-7	0.8
Sample_02_182	Cell line	Human melanoma	LOX-IMVI	0.043103448275862
Sample_02_183	Cell line	Skin	SKMEL2	0.23076923076923
Sample_02_219	Cell line	Mammary Gland	MDA-MB-231	0.22549019607843
Sample_02_220	Cell line	Brain	BE2C_1	0.20512820512821
Sample_02_237	Cell line	Colon	V389	0.15733480581631
Sample_02_250	Tissue	Brain	tumormodel3691	0.28125
Sample_02_298	Cell line	Neuroblastoma	CLB-GA	0.3013698630137
Sample_02_300	Cell line	Neuroblastoma	CLB-PE	0.17948717948718
Sample_02_310	Cell line	Neuroblastoma	SJNB8	0.10550458715596
Sample_02_314	Cell line	Neuroblastoma	SK-N-FI	0.24691358024691
Sample_02_317	Cell line	Neuroblastoma	GICAN	0.21621621621622
Sample_02_323	Cell line	Colon	RKO	0.2
Sample_02_338	Cell line	Neuroblastoma	BE2	0.17647058823529
Sample_02_355	Cell line	Colon	HCT15	0.29761904761905
Sample_02_356	Cell line	Colon	Sw480	0.25161290322581
Sample_02_358	Cell line	Colon	LS180	0.086492890995261
Sample_02_359	Cell line	Colon	Colo741	0.05421686746988
Sample_02_395	Cell line	Mammary Gland	BT-549	0.018741258741259
Sample_02_403	Cell line	Mammary Gland	T-47D_untreat	0.22727272727273
Sample_02_404	Cell line	Mammary Gland	ZR-75-1_2	0.38489208633094
Sample_02_413	Tissue	Brain	GBM_2493	0.2032967032967

ERF distribution in samples’ most representative CRC

Download

Sample ID	Tissue type	Biosample type	Biosample name
Sample_02_115	Mammary Gland	Cell line	MCF-7
Sample_02_219	Mammary Gland	Cell line	MDA-MB-231
Sample_02_404	Mammary Gland	Cell line	ZR-75-1_2

ERF distribution in all CRCs

Genomic distribution of SEs associated with ERF

Download

Mutation of ERF

Download

Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of ERF

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr19	42754489	42754489	G	A	exonic	ERF	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr19	42752751	42752751	C	G	exonic	ERF	nonsynonymous	CESC\|1\|194\|0.00515
-	chr19	42753847	42753847	A	C	exonic	ERF	synonymous	LIHC\|1\|373\|0.00268
-	chr19	42753340	42753340	C	A	exonic	ERF	nonsynonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr19	42754669	42754669	G	C	exonic	ERF	stopgain	HNSC\|1\|512\|0.00195
-	chr19	42753761	42753761	G	A	exonic	ERF	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr19	42752640	42752640	A	C	exonic	ERF	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr19	42753108	42753108	G	A	exonic	ERF	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr19	42753982	42753982	C	T	exonic	ERF	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs776977688	chr19	42754575	42754575	G	A	exonic	ERF	synonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr19	42752654	42752654	G	C	exonic	ERF	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr19	42752834	42752834	C	T	exonic	ERF	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs777136618	chr19	42753629	42753629	G	A	exonic	ERF	nonsynonymous	BLCA\|1\|396\|0.00253
rs760238666	chr19	42753748	42753748	G	A	exonic	ERF	synonymous	BLCA\|1\|396\|0.00253,HNSC\|1\|512\|0.00195
-	chr19	42752959	42752959	C	T	exonic	ERF	synonymous	UCEC\|1\|248\|0.00403
rs767131852	chr19	42752805	42752805	G	A	exonic	ERF	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr19	42753161	42753161	G	A	exonic	ERF	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr19	42752773	42752773	A	G	exonic	ERF	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr19	42753474	42753474	G	-	exonic	ERF	frameshift	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr19	42752723	42752723	C	T	exonic	ERF	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr19	42753410	42753410	G	A	exonic	ERF	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr19	42754650	42754650	C	T	exonic	ERF	stopgain	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr19	42754061	42754061	G	-	exonic	ERF	frameshift	PRAD\|1\|499\|0.00200
rs370521331	chr19	42754531	42754531	C	T	exonic	ERF	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr19	42753820	42753820	C	T	exonic	ERF	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs755151370	chr19	42753821	42753821	G	A	exonic	ERF	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr19	42754049	42754049	C	A	exonic	ERF	synonymous	HNSC\|1\|512\|0.00195
-	chr19	42753352	42753352	G	A	exonic	ERF	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs762382429	chr19	42752786	42752786	C	T	exonic	ERF	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr19	42752971	42752971	C	T	exonic	ERF	synonymous	SKCM\|1\|368\|0.00272
-	chr19	42753654	42753654	G	T	exonic	ERF	nonsynonymous	CESC\|1\|194\|0.00515
-	chr19	42754644	42754644	A	C	exonic	ERF	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr19	42752816	42752816	C	T	exonic	ERF	nonsynonymous	PAAD\|1\|185\|0.00541
rs767080643	chr19	42753648	42753648	C	T	exonic	ERF	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr19	42754040	42754040	G	A	exonic	ERF	synonymous	HNSC\|1\|512\|0.00195
rs745819984	chr19	42754535	42754535	C	T	exonic	ERF	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr19	42752695	42752695	C	-	exonic	ERF	frameshift	PRAD\|1\|499\|0.00200
-	chr19	42752989	42752989	G	A	exonic	ERF	synonymous	SKCM\|1\|368\|0.00272
-	chr19	42754700	42754700	A	G	exonic	ERF	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr19	42753286	42753286	G	A	exonic	ERF	synonymous	BRCA\|1\|982\|0.00102
-	chr19	42752804	42752804	C	A	exonic	ERF	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr19	42753519	42753519	G	T	exonic	ERF	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr19	42752824	42752824	G	C	exonic	ERF	synonymous	BLCA\|1\|396\|0.00253
-	chr19	42753689	42753689	C	T	exonic	ERF	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr19	42753761	42753761	G	T	exonic	ERF	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr19	42753023	42753023	C	A	exonic	ERF	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr19	42753866	42753866	G	A	exonic	ERF	nonsynonymous	ACC\|1\|90\|0.01111
rs138540323	chr19	42752782	42752782	G	A	exonic	ERF	synonymous	LUSC\|1\|178\|0.00562
-	chr19	42753425	42753425	G	A	exonic	ERF	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr19	42753179	42753179	G	A	exonic	ERF	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr19	42753005	42753005	G	A	exonic	ERF	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr19	42754547	42754547	G	A	exonic	ERF	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr19	42753164	42753164	G	A	exonic	ERF	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr19	42753278	42753278	C	T	exonic	ERF	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr19	42753026	42753026	-	C	exonic	ERF	frameshift	PAAD\|1\|185\|0.00541
rs577264310	chr19	42753169	42753169	C	T	exonic	ERF	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs61735151	chr19	42753283	42753283	G	A	exonic	ERF	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr19	42752741	42752741	C	A	exonic	ERF	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr19	42753150	42753151	AA	-	exonic	ERF	frameshift	PAAD\|23\|185\|0.12432,SKCM\|1\|368\|0.00272,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr19	42753762	42753762	A	G	exonic	ERF	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr19	42752618	42752618	C	T	exonic	ERF	synonymous	CESC\|1\|194\|0.00515
-	chr19	42753122	42753122	G	A	exonic	ERF	nonsynonymous	THCA\|1\|504\|0.00198
-	chr19	42752674	42752674	C	A	exonic	ERF	synonymous	BLCA\|1\|396\|0.00253
-	chr19	42752689	42752689	G	C	exonic	ERF	synonymous	LUSC\|1\|178\|0.00562
-	chr19	42752930	42752930	T	G	exonic	ERF	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr19	42754713	42754713	A	-	exonic	ERF	frameshift	PRAD\|1\|499\|0.00200
-	chr19	42753385	42753385	C	-	exonic	ERF	frameshift	LIHC\|1\|373\|0.00268
rs772092372	chr19	42754536	42754536	G	A	exonic	ERF	synonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr19	42753014	42753014	G	A	exonic	ERF	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr19	42753294	42753294	A	T	exonic	ERF	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr19	42754628	42754628	G	A	exonic	ERF	nonsynonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
rs780487406	chr19	42753368	42753368	C	-	exonic	ERF	frameshift	ESCA\|2\|185\|0.01081,SARC\|1\|247\|0.00405,STAD\|5\|395\|0.01266,STES\|5\|395\|0.01266
-	chr19	42754583	42754583	C	T	exonic	ERF	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr19	42753338	42753338	T	C	exonic	ERF	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr19	42753020	42753020	-	C	exonic	ERF	frameshift	PAAD\|1\|185\|0.00541
-	chr19	42754077	42754077	C	T	exonic	ERF	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr19	42753675	42753675	C	A	exonic	ERF	stopgain	CESC\|1\|194\|0.00515
rs770925496	chr19	42754072	42754072	G	A	exonic	ERF	synonymous	HNSC\|1\|512\|0.00195
-	chr19	42753613	42753613	-	T	exonic	ERF	frameshift	PRAD\|1\|499\|0.00200
-	chr19	42754675	42754675	G	C	exonic	ERF	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr19	42752808	42752808	G	A	exonic	ERF	nonsynonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr19	42753347	42753347	C	A	exonic	ERF	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr19	42752789	42752789	-	AA	exonic	ERF	frameshift	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr19	42752793	42752793	C	T	exonic	ERF	nonsynonymous	CESC\|1\|194\|0.00515
rs371203506	chr19	42753391	42753391	G	A	exonic	ERF	synonymous	LUAD\|1\|543\|0.00184
-	chr19	42753731	42753731	-	C	exonic	ERF	frameshift	HNSC\|1\|512\|0.00195
-	chr19	42753810	42753810	C	T	exonic	ERF	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs775069564	chr19	42753848	42753848	C	A	exonic	ERF	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204

Disease information of ERF

Download

TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
ERF	Arnold Chiari Malformation	C10;C16	Congenital Abnormality	CTD_human
ERF	Craniosynostosis	C05;C16	Disease or Syndrome	CTD_human;GENOMICS_ENGLAND
ERF	Hydrocephalus	C10	Disease or Syndrome	GENOMICS_ENGLAND
ERF	Language Delay	C10;C23	Finding	CTD_human
ERF	Language Development Disorders	C10;C23	Mental or Behavioral Dysfunction	CTD_human
ERF	Acrocephaly	C05;C16	Congenital Abnormality	CTD_human
ERF	Prostatic Neoplasms	C04;C12	Neoplastic Process	CTD_human
ERF	Brachycephaly	C05;C16	Congenital Abnormality	CTD_human
ERF	Speech Delay	C10;C23	Mental or Behavioral Dysfunction	CTD_human
ERF	Scaphycephaly	C05;C16	Congenital Abnormality	CTD_human;ORPHANET
ERF	Trigonocephaly	C05;C16	Congenital Abnormality	CTD_human
ERF	Malignant neoplasm of prostate	C04;C12	Neoplastic Process	CTD_human
ERF	Craniofacial Abnormalities	C05;C16	Congenital Abnormality	CTD_human
ERF	Semantic-Pragmatic Disorder	C10;C23	Mental or Behavioral Dysfunction	CTD_human
ERF	Chiari malformation type II	C10;C16	Congenital Abnormality	CTD_human
ERF	Arnold-Chiari Malformation, Type I	C10;C16	Congenital Abnormality	CTD_human
ERF	Arnold-Chiari Malformation, Type III	C10;C16	Congenital Abnormality	CTD_human
ERF	Arnold-Chiari Malformation, Type IV	C10;C16	Congenital Abnormality	CTD_human
ERF	Auditory Processing Disorder, Central	C10;C23	Disease or Syndrome	CTD_human
ERF	Synostotic Posterior Plagiocephaly	C05;C16	Disease or Syndrome	CTD_human;ORPHANET
ERF	Cloverleaf skull		Finding	ORPHANET
ERF	Metopic synostosis	C05;C16	Congenital Abnormality	CTD_human
ERF	Synostotic Anterior Plagiocephaly	C05;C16	Congenital Abnormality; Disease or Syndrome	CTD_human
ERF	Craniofacial dysostosis type 1	C05;C16	Disease or Syndrome	ORPHANET
ERF	Intellectual Disability	C10;C23;F01;F03	Mental or Behavioral Dysfunction	GENOMICS_ENGLAND
ERF	CRANIOSYNOSTOSIS 4		Disease or Syndrome	UNIPROT
ERF	CHITAYAT SYNDROME		Disease or Syndrome	CTD_human;UNIPROT

Pathway associated with ERF

Download

pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0000232	ATM pathway	pid	34	262
pathway0000903	General transcription regulation	panther	28	342
pathway0001543	Oncogene Induced Senescence	reactome	30	146
pathway0001604	PDGF signaling pathway	panther	113	1684
pathway0001662	Pink/Parkin Mediated Mitophagy	reactome	22	113
pathway0002297	Transcription regulation by bZIP transcription factor	panther	42	653
pathway0002299	Transcriptional activation of mitochondrial biogenesis	reactome	43	230

Go term information of ERF

Download

GO_term_name	GO_term_type	TF_name
GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR	BP	ERF
GO_RNA_DEPENDENT_DNA_BIOSYNTHETIC_PROCESS	BP	ERF
GO_POSITIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION	BP	ERF
GO_REGULATION_OF_DNA_RECOMBINATION	BP	ERF
GO_RIBOSOME_BIOGENESIS	BP	ERF
GO_NEGATIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERASE	BP	ERF
GO_DNA_TEMPLATED_TRANSCRIPTION_TERMINATION	BP	ERF
GO_REGULATION_OF_CELLULAR_SENESCENCE	BP	ERF
GO_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION	BP	ERF
GO_TELOMERE_CAPPING	BP	ERF
GO_NEGATIVE_REGULATION_OF_CELL_DIVISION	BP	ERF
GO_REGULATION_OF_MONOOXYGENASE_ACTIVITY	BP	ERF
GO_NEGATIVE_REGULATION_OF_DNA_REPAIR	BP	ERF
GO_CHROMOSOME_LOCALIZATION	BP	ERF
GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS	BP	ERF
GO_CHROMOSOME_LOCALIZATION_TO_NUCLEAR_ENVELOPE_INVOLVED_IN_HOMOLOGOUS_CHROMOSOME_SEGREGATION	BP	ERF
GO_NEGATIVE_REGULATION_OF_DNA_RECOMBINATION	BP	ERF
GO_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING	BP	ERF
GO_TELOMERE_ORGANIZATION	BP	ERF
GO_RIBOSOME_ASSEMBLY	BP	ERF
GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS	BP	ERF
GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR_VIA_HOMOLOGOUS_RECOMBINATION	BP	ERF
GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME	BP	ERF
GO_SPINDLE_CHECKPOINT	BP	ERF
GO_CELLULAR_SENESCENCE	BP	ERF
GO_REGULATION_OF_DNA_REPAIR	BP	ERF
GO_NEGATIVE_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION	BP	ERF
GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION	BP	ERF
GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION	BP	ERF
GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION	BP	ERF
GO_REGULATION_OF_NUCLEAR_CELL_CYCLE_DNA_REPLICATION	BP	ERF
GO_NEGATIVE_REGULATION_OF_TELOMERASE_ACTIVITY	BP	ERF
GO_NEGATIVE_REGULATION_OF_CELL_AGING	BP	ERF
GO_PROTEIN_OLIGOMERIZATION	BP	ERF
GO_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_ACTIVITY	BP	ERF
GO_AGING	BP	ERF
GO_NEGATIVE_REGULATION_OF_CHROMOSOME_SEGREGATION	BP	ERF
GO_REGULATION_OF_TELOMERE_MAINTENANCE	BP	ERF
GO_MEIOSIS_I	BP	ERF
GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION	BP	ERF
GO_POSITIVE_REGULATION_OF_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION	BP	ERF
GO_NEGATIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS	BP	ERF
GO_REGULATION_OF_MICROTUBULE_POLYMERIZATION	BP	ERF
GO_TELOMERE_LOCALIZATION	BP	ERF
GO_POSITIVE_REGULATION_OF_CELL_DIVISION	BP	ERF
GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME_TELOMERIC_REGION	BP	ERF
GO_NEGATIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING	BP	ERF
GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME	BP	ERF
GO_TRANSCRIPTION_FROM_MITOCHONDRIAL_PROMOTER	BP	ERF
GO_MITOTIC_NUCLEAR_DIVISION	BP	ERF
GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS	BP	ERF
GO_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY	BP	ERF
GO_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE	BP	ERF
GO_MITOCHONDRIAL_RNA_METABOLIC_PROCESS	BP	ERF
GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS	BP	ERF
GO_REGULATION_OF_HORMONE_BIOSYNTHETIC_PROCESS	BP	ERF
GO_DNA_BIOSYNTHETIC_PROCESS	BP	ERF
GO_REGULATION_OF_PROTEIN_ACETYLATION	BP	ERF
GO_TELOMERE_MAINTENANCE_VIA_TELOMERASE	BP	ERF
GO_CELL_CYCLE_G2_M_PHASE_TRANSITION	BP	ERF
GO_REGULATION_OF_PROTEIN_LOCALIZATION	BP	ERF
GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME_TELOMERIC_REGION	BP	ERF
GO_POSITIVE_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY	BP	ERF
GO_POSITIVE_REGULATION_OF_TELOMERE_MAINTENANCE	BP	ERF
GO_NEGATIVE_REGULATION_OF_CELLULAR_SENESCENCE	BP	ERF
GO_POSITIVE_REGULATION_OF_PROTEIN_ACETYLATION	BP	ERF
GO_POSITIVE_REGULATION_OF_MICROTUBULE_POLYMERIZATION	BP	ERF
GO_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS	BP	ERF
GO_STEROL_CATABOLIC_PROCESS	BP	ERF
GO_NEGATIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION	BP	ERF
GO_HOMOLOGOUS_CHROMOSOME_SEGREGATION	BP	ERF
GO_NEGATIVE_REGULATION_OF_NUCLEAR_DIVISION	BP	ERF
GO_NEGATIVE_REGULATION_OF_TELOMERE_MAINTENANCE	BP	ERF
GO_REGULATION_OF_TELOMERE_CAPPING	BP	ERF
GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION	BP	ERF
GO_POSITIVE_REGULATION_OF_NUCLEAR_DIVISION	BP	ERF
GO_REGULATION_OF_DNA_REPLICATION	BP	ERF
GO_REGULATION_OF_HORMONE_METABOLIC_PROCESS	BP	ERF
GO_POSITIVE_REGULATION_OF_MONOOXYGENASE_ACTIVITY	BP	ERF
GO_STEROL_METABOLIC_PROCESS	BP	ERF
GO_CELLULAR_MACROMOLECULE_LOCALIZATION	BP	ERF
GO_POSITIVE_REGULATION_OF_CELL_CYCLE	BP	ERF
GO_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING	BP	ERF
GO_POSITIVE_REGULATION_OF_PROTEIN_POLYMERIZATION	BP	ERF
GO_POSITIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION	BP	ERF
GO_NEGATIVE_REGULATION_OF_DNA_REPLICATION	BP	ERF
GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION	BP	ERF
GO_POSITIVE_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_ACTIVITY	BP	ERF
GO_CIRCULATORY_SYSTEM_DEVELOPMENT	BP	ERF
GO_REGULATION_OF_TELOMERASE_ACTIVITY	BP	ERF
GO_REGULATION_OF_CELL_AGING	BP	ERF
GO_ALCOHOL_CATABOLIC_PROCESS	BP	ERF
GO_STEROID_CATABOLIC_PROCESS	BP	ERF
GO_NUCLEAR_CHROMOSOME_TELOMERIC_REGION	CC	ERF
GO_NUCLEOID	CC	ERF
GO_LARGE_RIBOSOMAL_SUBUNIT	CC	ERF
GO_PROTEIN_DNA_COMPLEX	CC	ERF
GO_ORGANELLAR_RIBOSOME	CC	ERF
GO_NUCLEOPLASM_PART	CC	ERF
GO_MITOCHONDRION	CC	ERF
GO_ORGANELLAR_LARGE_RIBOSOMAL_SUBUNIT	CC	ERF
GO_TELOMERE_CAP_COMPLEX	CC	ERF
GO_HISTONE_DEACETYLASE_COMPLEX	CC	ERF
GO_DNA_POLYMERASE_ACTIVITY	MF	ERF
GO_DNA_BINDING_BENDING	MF	ERF
GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_BINDING	MF	ERF
GO_RNA_DIRECTED_DNA_POLYMERASE_ACTIVITY	MF	ERF
GO_TELOMERIC_DNA_BINDING	MF	ERF
GO_LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_TRANSCRIPTION_COACTIVATOR_ACTIVITY	MF	ERF
GO_TRANSCRIPTION_COACTIVATOR_ACTIVITY	MF	ERF

Survival analysis of ERF

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of ERF

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)