Sample overview of T-47D_untreat

Sample ID: Sample_02_403
Biosample type: Cell line
Tissue type: Mammary Gland
Biosample name: T-47D_untreat
Data source: NCBI GEO/SRA
GSE ID: GSE69112
Cancer type: Breast cancer
CRC number: 88
TF number of all CRCs: 31
TF list of all CRCs: GATA3, TFAP2A, FOXA1, XBP1, EHF, SPDEF, HOXC10, HES1, ESR1, RREB1, RARA, BCL6, NR2F2, PBX1, IRX5, RXRA, HOXC9, HOXC11, TP63, SOX12, ZBTB7B, JUNB, BARX2, HOXB2, ERF, BACH1, SATB1, RARG, TEAD3, KLF16, ZNF217

The most representative CRC of T-47D_untreat
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Relationship plot of CRC model
TF number of this CRC: 19
CRC socre: 67.15789
TF list of the most representative CRC
TF name TF family Frequency of TFs
BCL6 ZBTB 61 / 88
EHF ETS 88 / 88
ESR1 ESR-like 69 / 88
FOXA1 Fork_head 88 / 88
GATA3 zf-GATA 88 / 88
HES1 bHLH 71 / 88
HOXC10 Homeobox 79 / 88
HOXC11 Homeobox 40 / 88
HOXC9 Homeobox 40 / 88
IRX5 Homeobox 53 / 88
NR2F2 RXR-like 60 / 88
PBX1 Homeobox 59 / 88
RARA THR-like 61 / 88
RREB1 zf-C2H2 68 / 88
RXRA RXR-like 52 / 88
SPDEF ETS 88 / 88
TFAP2A AP-2 88 / 88
TP63 P53 35 / 88
XBP1 TF_bZIP 88 / 88

All CRCs of T-47D_untreat
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
SPDEF 88 / 88 ETS ENSG00000124664
TFAP2A 88 / 88 AP-2 ENSG00000137203
XBP1 88 / 88 TF_bZIP ENSG00000100219
EHF 88 / 88 ETS ENSG00000135373
FOXA1 88 / 88 Fork_head ENSG00000129514
GATA3 88 / 88 zf-GATA ENSG00000107485
HOXC10 79 / 88 Homeobox ENSG00000180818
HES1 71 / 88 bHLH ENSG00000114315
ESR1 69 / 88 ESR-like ENSG00000091831
RREB1 68 / 88 zf-C2H2 ENSG00000124782
RARA 61 / 88 THR-like ENSG00000131759
BCL6 61 / 88 ZBTB ENSG00000113916
NR2F2 60 / 88 RXR-like ENSG00000185551
PBX1 59 / 88 Homeobox ENSG00000185630
IRX5 53 / 88 Homeobox ENSG00000176842
RXRA 52 / 88 RXR-like ENSG00000186350
HOXC9 40 / 88 Homeobox ENSG00000180806
HOXC11 40 / 88 Homeobox ENSG00000123388
TP63 35 / 88 P53 ENSG00000073282
SOX12 34 / 88 HMG ENSG00000177732
ZBTB7B 31 / 88 ZBTB ENSG00000160685
JUNB 29 / 88 TF_bZIP ENSG00000171223
BARX2 27 / 88 Homeobox ENSG00000043039
HOXB2 26 / 88 Homeobox ENSG00000173917
ERF 20 / 88 ETS ENSG00000105722
BACH1 19 / 88 TF_bZIP ENSG00000156273
SATB1 17 / 88 CUT ENSG00000182568
RARG 14 / 88 THR-like ENSG00000172819
TEAD3 14 / 88 TEA ENSG00000007866
KLF16 10 / 88 zf-C2H2 ENSG00000129911
ZNF217 9 / 88 zf-C2H2 ENSG00000171940

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
HOXC9 33 44 77
ZNF217 34 33 67
JUNB 31 46 77
ERF 34 34 68
TEAD3 27 49 76
TP63 30 43 73
XBP1 34 44 78
RARA 33 48 81
FOXA1 34 48 82
KLF16 29 46 75
TFAP2A 34 48 82
BACH1 25 42 67
NR2F2 33 45 78
IRX5 34 45 79
RREB1 33 48 81
ZBTB7B 31 47 78
HOXB2 34 40 74
RXRA 32 47 79
HOXC11 33 43 76
HOXC10 33 47 80
SATB1 29 45 74
GATA3 34 49 83
PBX1 34 44 78
EHF 34 49 83
BARX2 33 39 72
RARG 29 47 76
ESR1 34 48 82
SPDEF 34 49 83
HES1 34 45 79
BCL6 32 49 81
SOX12 30 48 78

Expression of TFs in all CRCs