TF information

TF name: GATA3
TF family: zf-GATA
Ensembl gene ID: ENSG00000107485
Ensembl protein ID: ENSP00000341619, ENSP00000494926, ENSP00000368632
Entrez gene ID: 2625
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of GATA3 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_01_046Cell lineMammary GlandMCF-70.5
Sample_02_007OtherCervicalcervical-cancer_vector0.11258278145695
Sample_02_078Primary cellNeuroblastomalow-MYCN-Neuroblastoma-patient-cells0.5
Sample_02_079Cell lineMammary GlandT-47D_11
Sample_02_096Cell lineMammary GlandZR-75-1_10.45652173913043
Sample_02_115Cell lineMammary GlandMCF-71
Sample_02_166Cell lineMammary GlandHCC1954_Parental0.356
Sample_02_220Cell lineBrainBE2C_10.66666666666667
Sample_02_254Cell lineNeuroblastomaIMR5-750.76470588235294
Sample_02_296Cell lineNeuroblastomaCLB-BER-Lud0.49808722264728
Sample_02_298Cell lineNeuroblastomaCLB-GA0.3013698630137
Sample_02_299Cell lineNeuroblastomaCLB-MA0.29736211031175
Sample_02_302Cell lineNeuroblastomaIMR320.67857142857143
Sample_02_303Cell lineNeuroblastomaLAN10.68571428571429
Sample_02_304Cell lineNeuroblastomaN2060.5570652173913
Sample_02_307Cell lineNeuroblastomaSJNB120.57746478873239
Sample_02_308Cell lineNeuroblastomaSJNB10.625
Sample_02_309Cell lineNeuroblastomaSJNB60.67298578199052
Sample_02_310Cell lineNeuroblastomaSJNB80.37418086500655
Sample_02_311Cell lineNeuroblastomaSK-N-AS0.64935064935065
Sample_02_312Cell lineNeuroblastomaSK-N-BE_2-C0.52127659574468
Sample_02_313Cell lineNeuroblastomaSK-N-DZ0.76833976833977
Sample_02_314Cell lineNeuroblastomaSK-N-FI0.30864197530864
Sample_02_316Cell lineNeuroblastomaCHP2120.56593406593407
Sample_02_317Cell lineNeuroblastomaGICAN0.89189189189189
Sample_02_318Cell lineNeuroblastomaNB690.546875
Sample_02_319Cell lineNeuroblastomaNB-EBc10.5028901734104
Sample_02_338Cell lineNeuroblastomaBE20.63235294117647
Sample_02_394Cell lineMammary GlandT-47D_21
Sample_02_403Cell lineMammary GlandT-47D_untreat1
Sample_02_404Cell lineMammary GlandZR-75-1_21

GATA3 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_079Mammary GlandCell lineT-47D_1
Sample_02_115Mammary GlandCell lineMCF-7
Sample_02_220BrainCell lineBE2C_1
Sample_02_254NeuroblastomaCell lineIMR5-75
Sample_02_296NeuroblastomaCell lineCLB-BER-Lud
Sample_02_302NeuroblastomaCell lineIMR32
Sample_02_303NeuroblastomaCell lineLAN1
Sample_02_304NeuroblastomaCell lineN206
Sample_02_307NeuroblastomaCell lineSJNB12
Sample_02_308NeuroblastomaCell lineSJNB1
Sample_02_309NeuroblastomaCell lineSJNB6
Sample_02_311NeuroblastomaCell lineSK-N-AS
Sample_02_312NeuroblastomaCell lineSK-N-BE_2-C
Sample_02_313NeuroblastomaCell lineSK-N-DZ
Sample_02_314NeuroblastomaCell lineSK-N-FI
Sample_02_316NeuroblastomaCell lineCHP212
Sample_02_317NeuroblastomaCell lineGICAN
Sample_02_318NeuroblastomaCell lineNB69
Sample_02_338NeuroblastomaCell lineBE2
Sample_02_394Mammary GlandCell lineT-47D_2
Sample_02_403Mammary GlandCell lineT-47D_untreat
Sample_02_404Mammary GlandCell lineZR-75-1_2

GATA3 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with GATA3
Download

Mutation of GATA3
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of GATA3

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr1081159658115965-AexonicGATA3frameshift BRCA|2|982|0.00204
-chr1081158608115860CTexonicGATA3synonymous SKCM|1|368|0.00272
-chr1081158298115829ATexonicGATA3nonsynonymous OV|1|469|0.00213
-chr1081115078111507-GexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081060938106093CTexonicGATA3stopgain STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081159268115926GCexonicGATA3synonymous HNSC|1|512|0.00195
-chr1081159268115926-CexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081158748115874-GexonicGATA3frameshift BRCA|7|982|0.00713
-chr1081157798115779-AexonicGATA3frameshift COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs769298101chr1081159078115907CTexonicGATA3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1081159748115976CGC-exonicGATA3nonframeshift BRCA|1|982|0.00102
-chr1081115138111513-GexonicGATA3frameshift BRCA|7|982|0.00713
-chr1081159758115975GAexonicGATA3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081158748115874CGexonicGATA3nonsynonymous HNSC|1|512|0.00195
-chr1081005538100553CAexonicGATA3nonsynonymous HNSC|1|512|0.00195
rs201023943chr1081005148100514CTexonicGATA3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204,UCEC|1|248|0.00403
-chr1081005078100507GAexonicGATA3nonsynonymous DLBC|1|48|0.02083
-chr1081158778115877CAexonicGATA3nonsynonymous BRCA|1|982|0.00102,OV|1|469|0.00213
-chr1081004398100439CTexonicGATA3nonsynonymous BLCA|1|396|0.00253
rs760084913chr1081060928106092GAexonicGATA3synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081159788115978-TexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081004098100409GAexonicGATA3nonsynonymous SKCM|1|368|0.00272
rs770601456chr1081004308100430CTexonicGATA3nonsynonymous BLCA|1|396|0.00253
-chr1081002688100268GAexonicGATA3nonsynonymous SKCM|2|368|0.00543
-chr1080978188097818CAexonicGATA3stopgain LUSC|1|178|0.00562
-chr1081158248115824GCexonicGATA3synonymous BLCA|1|396|0.00253
-chr1081115048111504GAexonicGATA3synonymous SKCM|2|368|0.00543
-chr1081003868100386GAexonicGATA3synonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr1081004518100451-GexonicGATA3frameshift KIPAN|2|799|0.00250,KIRC|2|451|0.00443
-chr1081004758100475TCexonicGATA3nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr1081157068115706A-exonicGATA3frameshift BRCA|1|982|0.00102
-chr1081005198100519CAexonicGATA3nonsynonymous LUSC|1|178|0.00562
-chr1080976538097653GAexonicGATA3nonsynonymous ESCA|1|185|0.00541
rs2228255chr1081007768100776GAexonicGATA3synonymous LUAD|1|543|0.00184
-chr1081115588111558-ATAexonicGATA3nonframeshift BRCA|1|982|0.00102
-chr1081159288115928-TexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081003918100391TCexonicGATA3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1081005578100557GAexonicGATA3synonymous LUAD|1|543|0.00184
-chr1081115008111500GAexonicGATA3nonsynonymous BRCA|1|982|0.00102
rs143582578chr1081007348100734CAexonicGATA3synonymous HNSC|1|512|0.00195
-chr1081060048106004GAexonicGATA3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1081114498111449GAexonicGATA3nonsynonymous UCEC|1|248|0.00403
-chr1081115128111512-TexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081114348111434A-splicingGATA3unknown BRCA|20|982|0.02037
-chr1081003308100330GAexonicGATA3nonsynonymous SKCM|2|368|0.00543
-chr1081115078111507T-exonicGATA3frameshift BRCA|1|982|0.00102
-chr1081159418115941-TexonicGATA3frameshift BRCA|3|982|0.00305
rs774440409chr1081060758106075CAexonicGATA3nonsynonymous LIHC|1|373|0.00268
-chr1081004098100409GTexonicGATA3nonsynonymous CHOL|1|35|0.02857
-chr1081003868100386GTexonicGATA3synonymous LUAD|1|543|0.00184
-chr1081159318115931CTexonicGATA3nonsynonymous SKCM|1|368|0.00272
-chr1081004458100445CTexonicGATA3nonsynonymous SKCM|1|368|0.00272
-chr1081157808115780A-exonicGATA3frameshift COAD|1|367|0.00272,COADREAD|1|489|0.00204,STAD|3|395|0.00759,STES|3|395|0.00759
-chr1081158748115874C-exonicGATA3frameshift BRCA|1|982|0.00102
rs776668722chr1081007288100728C-exonicGATA3frameshift COAD|1|367|0.00272,COADREAD|1|489|0.00204,STAD|2|395|0.00506,STES|2|395|0.00506
-chr1081114978111497GAexonicGATA3stopgain BRCA|1|982|0.00102
-chr1081003488100348ATexonicGATA3nonsynonymous LUSC|1|178|0.00562
-chr1081059838105983CAexonicGATA3nonsynonymous LUAD|4|543|0.00737
-chr1081159888115988GCUTR3GATA3unknown STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081159228115922-CexonicGATA3frameshift BRCA|1|982|0.00102
-chr1080977498097749CTexonicGATA3nonsynonymous UCS|1|57|0.01754
-chr1081004088100408GAexonicGATA3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081002878100287GAexonicGATA3synonymous UCEC|1|248|0.00403
-chr1081159798115979-GexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081115178111517GCexonicGATA3nonsynonymous LUAD|1|543|0.00184
rs138698611chr1081060268106026CTexonicGATA3synonymous LIHC|1|373|0.00268
rs112417755chr1081157018115701GCsplicingGATA3splicing BRCA|1|982|0.00102
-chr1081004498100449GAexonicGATA3synonymous BRCA|1|982|0.00102
-chr1081159478115947AGexonicGATA3synonymous LIHC|1|373|0.00268
-chr1081004798100479CTexonicGATA3synonymous BLCA|1|396|0.00253
-chr1081006688100668G-exonicGATA3frameshift HNSC|1|512|0.00195
-chr1081157468115746ATexonicGATA3nonsynonymous BRCA|1|982|0.00102
-chr1081159828115982-TexonicGATA3frameshift BRCA|1|982|0.00102
rs767671768chr1081006318100631GAexonicGATA3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081159818115981GTexonicGATA3nonsynonymous ACC|1|90|0.01111
-chr1081158728115872C-exonicGATA3frameshift BRCA|1|982|0.00102
-chr1081159608115960-CexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081114788111478ATexonicGATA3nonsynonymous LUAD|1|543|0.00184
-chr1081159178115917GTexonicGATA3synonymous LUSC|1|178|0.00562
-chr1081115508111550ATexonicGATA3stopgain BRCA|1|982|0.00102
-chr1081007418100741CTexonicGATA3synonymous LUAD|1|543|0.00184
-chr1081158888115888-CexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081115468111546-ACTexonicGATA3nonframeshift BRCA|1|982|0.00102
-chr1081157588115758GAexonicGATA3nonsynonymous LUSC|1|178|0.00562
rs541782074chr1081159178115917GAexonicGATA3synonymous SKCM|2|368|0.00543
-chr1081158628115862-CexonicGATA3frameshift BRCA|1|982|0.00102
rs575091chr1081060478106047CTexonicGATA3synonymous BLCA|1|396|0.00253
-chr1081158538115853T-exonicGATA3frameshift BRCA|1|982|0.00102
-chr1081005518100551GAexonicGATA3synonymous OV|1|469|0.00213
-chr1081158238115823CTexonicGATA3nonsynonymous BLCA|1|396|0.00253
-chr1081159528115952-CexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081159638115963-CexonicGATA3frameshift BLCA|1|396|0.00253
-chr1081006228100622CTexonicGATA3nonsynonymous OV|1|469|0.00213
-chr1080978498097849GAexonicGATA3synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081115398111539GAexonicGATA3nonsynonymous SKCM|1|368|0.00272
-chr1081114968111496-GAGexonicGATA3stopgain BRCA|1|982|0.00102
-chr1081115158111515G-exonicGATA3frameshift BRCA|1|982|0.00102
-chr1081114978111497G-exonicGATA3stopgain BRCA|1|982|0.00102
-chr1080978258097825GAexonicGATA3synonymous LIHC|1|373|0.00268
-chr1081158328115832-GexonicGATA3frameshift BRCA|1|982|0.00102
rs199565632chr1081007288100728CTexonicGATA3synonymous BLCA|1|396|0.00253
-chr1081157118115711C-exonicGATA3frameshift BRCA|1|982|0.00102
-chr1081159808115980GTexonicGATA3nonsynonymous LUAD|2|543|0.00368
-chr1081059788105978-GexonicGATA3frameshift ESCA|1|185|0.00541
-chr1081004258100425C-exonicGATA3frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081159438115943T-exonicGATA3frameshift BRCA|1|982|0.00102
-chr1081004528100452G-exonicGATA3frameshift COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1081159558115955-CexonicGATA3frameshift BRCA|2|982|0.00204
-chr1081158748115874-TexonicGATA3frameshift BRCA|2|982|0.00204
-chr1081114718111471-TexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081159588115958CGexonicGATA3nonsynonymous LUSC|1|178|0.00562
-chr1081004088100408GTexonicGATA3nonsynonymous LUAD|2|543|0.00368
rs776412274chr1081003518100351GAexonicGATA3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081158618115861-TexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081159298115929A-exonicGATA3frameshift BLCA|1|396|0.00253
-chr1081060588106058TGexonicGATA3nonsynonymous BRCA|1|982|0.00102
-chr1081003168100316TAexonicGATA3nonsynonymous HNSC|1|512|0.00195
-chr1081060938106093-GexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081157208115720AGexonicGATA3nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
rs774889150chr1081007088100708GAexonicGATA3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081007168100716CAexonicGATA3nonsynonymous PAAD|1|185|0.00541
rs374919553chr1081159138115913CTexonicGATA3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081060128106012GAexonicGATA3nonsynonymous LUAD|4|543|0.00737
rs369321512chr1081159148115914GAexonicGATA3synonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr1081004708100470GAexonicGATA3synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204,STAD|1|395|0.00253,STES|1|395|0.00253
rs150229374chr1081158248115824GAexonicGATA3synonymous UCEC|1|248|0.00403
rs752977342chr1081158748115874CTexonicGATA3nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222,SKCM|2|368|0.00543
-chr1081006648100664CTexonicGATA3nonsynonymous BLCA|2|396|0.00505
-chr1081115428111542TCexonicGATA3nonsynonymous COAD|3|367|0.00817,COADREAD|3|489|0.00613
-chr1081157268115728AAG-exonicGATA3nonframeshift BRCA|1|982|0.00102
-chr1081114358111435GTsplicingGATA3splicing LUAD|1|543|0.00184
-chr1081060738106073GAexonicGATA3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1081060948106094GAexonicGATA3nonsynonymous BRCA|1|982|0.00102
-chr1081006418100641GAexonicGATA3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081114678111467CAexonicGATA3nonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr1081158108115810C-exonicGATA3frameshift BRCA|1|982|0.00102
-chr1081060978106097G-exonicGATA3frameshift LUAD|1|543|0.00184
-chr1081007468100746G-exonicGATA3frameshift STAD|1|395|0.00253,STES|1|395|0.00253
rs746122348chr1081060418106041CTexonicGATA3synonymous HNSC|1|512|0.00195
-chr1081004998100499CTexonicGATA3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1081159058115905CTexonicGATA3synonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr1081059928105992CAexonicGATA3nonsynonymous SARC|1|247|0.00405
rs771019738chr1081007278100727-CexonicGATA3frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081159028115902GAexonicGATA3synonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
rs2228254chr1081006328100632TCexonicGATA3synonymous DLBC|1|48|0.02083
-chr1081157738115773ACexonicGATA3nonsynonymous TGCT|1|155|0.00645
-chr1080976798097679GAexonicGATA3nonsynonymous ESCA|1|185|0.00541
-chr1081159858115985-CexonicGATA3stoploss BRCA|1|982|0.00102
-chr1081060588106058TAexonicGATA3nonsynonymous BRCA|3|982|0.00305
-chr1081004518100451CTexonicGATA3nonsynonymous HNSC|1|512|0.00195
-chr1081115438111543-TexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081158588115858TCexonicGATA3nonsynonymous COAD|3|367|0.00817,COADREAD|3|489|0.00613
rs200935603chr1081158378115837GAexonicGATA3nonsynonymous BLCA|1|396|0.00253,COAD|1|367|0.00272,COADREAD|1|489|0.00204,PAAD|1|185|0.00541,STAD|2|395|0.00506,STES|2|395|0.00506
-chr1081005798100579AGexonicGATA3nonsynonymous HNSC|1|512|0.00195
-chr1081007898100789GAexonicGATA3nonsynonymous DLBC|1|48|0.02083
-chr1081158518115851-AexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081158438115843-CexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081060318106031GAexonicGATA3nonsynonymous HNSC|1|512|0.00195
-chr1080977678097767TAexonicGATA3nonsynonymous HNSC|1|512|0.00195
-chr1081005638100563CTexonicGATA3synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081157038115703T-exonicGATA3frameshift BRCA|1|982|0.00102
-chr1081006268100626CGexonicGATA3nonsynonymous LUAD|1|543|0.00184
-chr1081060228106022AGexonicGATA3nonsynonymous BRCA|1|982|0.00102
-chr1080977868097786ACexonicGATA3nonsynonymous ESCA|1|185|0.00541
-chr1081005368100536ATexonicGATA3synonymous LUAD|1|543|0.00184
-chr1081059648105964GAexonicGATA3nonsynonymous BRCA|1|982|0.00102
-chr1081159288115928-AexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081060868106086GTexonicGATA3nonsynonymous LUAD|1|543|0.00184
-chr1081157028115704ATT-exonicGATA3nonframeshift BRCA|1|982|0.00102
-chr1081157208115720A-exonicGATA3stopgain BRCA|1|982|0.00102
-chr1081114878111487AGexonicGATA3nonsynonymous UCEC|1|248|0.00403
-chr1081003798100379CTexonicGATA3nonsynonymous LUSC|1|178|0.00562
-chr1081002698100269GTexonicGATA3synonymous BLCA|1|396|0.00253
-chr1081004408100440CGexonicGATA3synonymous BRCA|1|982|0.00102
rs745734873chr1081004378100437GAexonicGATA3synonymous GBMLGG|2|820|0.00244,HNSC|1|512|0.00195,LGG|2|530|0.00377
-chr1081159748115974CAexonicGATA3synonymous LUAD|1|543|0.00184
rs750735308chr1081003858100385CTexonicGATA3nonsynonymous CHOL|1|35|0.02857
-chr1081157508115750CAexonicGATA3synonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr1081157108115710-CexonicGATA3frameshift BRCA|1|982|0.00102
-chr1081158738115873-CexonicGATA3frameshift BRCA|2|982|0.00204
-chr1081114588111458CTexonicGATA3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1081158468115846ATexonicGATA3stopgain LUAD|1|543|0.00184
-chr1081006448100644CTexonicGATA3synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1081159558115955A-exonicGATA3frameshift BRCA|1|982|0.00102
-chr1080976818097681GTexonicGATA3synonymous ESCA|1|185|0.00541
-chr1081114998111499A-exonicGATA3frameshift BRCA|1|982|0.00102
-chr1081158078115807TGexonicGATA3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1081003978100397-GGexonicGATA3frameshift ACC|1|90|0.01111
rs778161799chr1081006008100600GAexonicGATA3nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr1081003258100325GAexonicGATA3nonsynonymous PAAD|1|185|0.00541
rs749708566chr1081007548100754CTexonicGATA3nonsynonymous SKCM|2|368|0.00543
-chr1081157198115719TAexonicGATA3synonymous LUAD|2|543|0.00368
-chr1081158768115876-GexonicGATA3frameshift BRCA|1|982|0.00102

Disease information of GATA3
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
GATA3 Rheumatoid Arthritis C05;C17;C20 Disease or Syndrome CTD_human
GATA3 Malignant neoplasm of breast C04;C17 Neoplastic Process CGI;UNIPROT
GATA3 Burkitt Lymphoma C02;C04;C15;C20 Neoplastic Process ORPHANET
GATA3 Carcinoma C04 Neoplastic Process CTD_human
GATA3 Eosinophilia C15 Disease or Syndrome CTD_human
GATA3 Eosinophilia, Tropical C15 Disease or Syndrome CTD_human
GATA3 Hodgkin Disease C04;C15;C20 Neoplastic Process CTD_human
GATA3 Inflammation C23 Pathologic Function CTD_human
GATA3 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma C04;C15;C20 Neoplastic Process CTD_human
GATA3 Adult T-Cell Lymphoma/Leukemia C04;C15;C20 Neoplastic Process CTD_human
GATA3 Animal Mammary Neoplasms C04;C22 Neoplastic Process CTD_human
GATA3 Mammary Neoplasms, Experimental C04 Experimental Model of Disease; Neoplastic Process CTD_human
GATA3 Metaplasia C23 Cell or Molecular Dysfunction CTD_human
GATA3 Mixed Cellularity Hodgkin Lymphoma C04;C15;C20 Neoplastic Process CTD_human
GATA3 Hodgkin lymphoma, lymphocyte depletion C04;C15;C20 Neoplastic Process CTD_human
GATA3 Anaplastic carcinoma C04 Neoplastic Process CTD_human
GATA3 Carcinoma, Spindle-Cell C04 Neoplastic Process CTD_human
GATA3 Undifferentiated carcinoma C04 Neoplastic Process CTD_human
GATA3 Carcinomatosis C04 Neoplastic Process CTD_human
GATA3 Adult Hodgkin Lymphoma C04;C15;C20 Neoplastic Process CTD_human
GATA3 Neoplasm of uncertain or unknown behavior of breast Neoplastic Process CGI
GATA3 Breast Carcinoma C04;C17 Neoplastic Process CGI
GATA3 Breast adenocarcinoma Neoplastic Process CGI
GATA3 Mammary Carcinoma, Animal C04;C22 Neoplastic Process CTD_human
GATA3 Lymphocyte Rich Classical Hodgkin Lymphoma C04;C15;C20 Neoplastic Process CTD_human
GATA3 Precursor B-cell lymphoblastic leukemia Neoplastic Process ORPHANET
GATA3 Nodular Lymphocyte Predominant Hodgkin Lymphoma C04;C15;C20 Neoplastic Process CTD_human
GATA3 Barakat syndrome C09;C10;C12;C13;C19;C23 Disease or Syndrome CTD_human;ORPHANET;UNIPROT
GATA3 Cakut C12;C13;C16 Disease or Syndrome GENOMICS_ENGLAND

Pathway associated with GATA3
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0000335 C-MYB transcription factor network pid 87 525
pathway0000343 Calcineurin-regulated NFAT-dependent transcription in lymphocytes pid 50 304
pathway0000747 Factors involved in megakaryocyte development and platelet production reactome 111 689
pathway0000916 Glucocorticoid receptor regulatory network pid 85 876
pathway0001124 IL27-mediated signaling events pid 26 217
pathway0001523 Notch signaling pathway pid 58 321
pathway0001849 Regulation of nuclear SMAD2/3 signaling pid 82 1072
pathway0002725 Hs_Endochondral_Ossification_WP474_87977 wikipathways 43 117
pathway0002755 Hs_White_fat_cell_differentiation_WP3946_90940 wikipathways 30 59

Go term information of GATA3
GO_term_name GO_term_type TF_name
GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION BP GATA3
GO_NEGATIVE_REGULATION_OF_KIDNEY_DEVELOPMENT BP GATA3
GO_PHENOL_CONTAINING_COMPOUND_METABOLIC_PROCESS BP GATA3
GO_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION BP GATA3
GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS BP GATA3
GO_EMBRYONIC_HEMOPOIESIS BP GATA3
GO_RESPONSE_TO_IONIZING_RADIATION BP GATA3
GO_REGULATION_OF_INTERLEUKIN_4_PRODUCTION BP GATA3
GO_REGULATION_OF_FAT_CELL_DIFFERENTIATION BP GATA3
GO_URETER_DEVELOPMENT BP GATA3
GO_REGULATION_OF_INTERLEUKIN_5_PRODUCTION BP GATA3
GO_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS BP GATA3
GO_POSITIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE BP GATA3
GO_CARDIAC_SEPTUM_DEVELOPMENT BP GATA3
GO_PHENOL_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS BP GATA3
GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION BP GATA3
GO_POSITIVE_REGULATION_OF_HEMOPOIESIS BP GATA3
GO_REGULATION_OF_MAMMARY_GLAND_EPITHELIAL_CELL_PROLIFERATION BP GATA3
GO_METANEPHROS_DEVELOPMENT BP GATA3
GO_RESPONSE_TO_INTERLEUKIN_4 BP GATA3
GO_CARDIAC_CHAMBER_MORPHOGENESIS BP GATA3
GO_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS BP GATA3
GO_NEGATIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION BP GATA3
GO_MESENCHYMAL_TO_EPITHELIAL_TRANSITION BP GATA3
GO_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE BP GATA3
GO_POSITIVE_REGULATION_OF_BINDING BP GATA3
GO_THYMIC_T_CELL_SELECTION BP GATA3
GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE BP GATA3
GO_PROTEIN_SECRETION BP GATA3
GO_OTIC_VESICLE_DEVELOPMENT BP GATA3
GO_POSITIVE_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS BP GATA3
GO_ALPHA_BETA_T_CELL_DIFFERENTIATION BP GATA3
GO_POSITIVE_REGULATION_OF_KIDNEY_DEVELOPMENT BP GATA3
GO_MYELOID_LEUKOCYTE_DIFFERENTIATION BP GATA3
GO_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE BP GATA3
GO_NEGATIVE_REGULATION_OF_LOCOMOTION BP GATA3
GO_REGULATION_OF_DEFENSE_RESPONSE BP GATA3
GO_THYMUS_DEVELOPMENT BP GATA3
GO_HORMONE_TRANSPORT BP GATA3
GO_CATECHOLAMINE_METABOLIC_PROCESS BP GATA3
GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT BP GATA3
GO_LEUKOCYTE_DIFFERENTIATION BP GATA3
GO_MORPHOGENESIS_OF_EMBRYONIC_EPITHELIUM BP GATA3
GO_POSITIVE_REGULATION_OF_HORMONE_METABOLIC_PROCESS BP GATA3
GO_ORGAN_MATURATION BP GATA3
GO_WNT_SIGNALING_PATHWAY BP GATA3
GO_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS BP GATA3
GO_POSITIVE_REGULATION_OF_DNA_BINDING BP GATA3
GO_REGULATION_OF_MESONEPHROS_DEVELOPMENT BP GATA3
GO_RESPONSE_TO_INTERFERON_ALPHA BP GATA3
GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_4 BP GATA3
GO_NEGATIVE_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY BP GATA3
GO_DIGESTIVE_SYSTEM_DEVELOPMENT BP GATA3
GO_ANATOMICAL_STRUCTURE_MATURATION BP GATA3
GO_REGULATION_OF_CELL_PROLIFERATION_INVOLVED_IN_KIDNEY_DEVELOPMENT BP GATA3
GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION BP GATA3
GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS BP GATA3
GO_NEPHRIC_DUCT_DEVELOPMENT BP GATA3
GO_INTRACELLULAR_SIGNAL_TRANSDUCTION BP GATA3
GO_REGULATION_OF_KIDNEY_DEVELOPMENT BP GATA3
GO_THYMOCYTE_AGGREGATION BP GATA3
GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS BP GATA3
GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION BP GATA3
GO_POSITIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE BP GATA3
GO_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE BP GATA3
GO_CELL_MATURATION BP GATA3
GO_LYMPHOCYTE_MEDIATED_IMMUNITY BP GATA3
GO_REGULATION_OF_NEURON_DIFFERENTIATION BP GATA3
GO_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION BP GATA3
GO_CANONICAL_WNT_SIGNALING_PATHWAY BP GATA3
GO_ACUTE_INFLAMMATORY_RESPONSE BP GATA3
GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY BP GATA3
GO_REGULATION_OF_DNA_BINDING BP GATA3
GO_RESPONSE_TO_HORMONE BP GATA3
GO_CATECHOLAMINE_BIOSYNTHETIC_PROCESS BP GATA3
GO_CARDIAC_VENTRICLE_MORPHOGENESIS BP GATA3
GO_INTERFERON_GAMMA_PRODUCTION BP GATA3
GO_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY BP GATA3
GO_CARDIAC_RIGHT_VENTRICLE_MORPHOGENESIS BP GATA3
GO_SYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT BP GATA3
GO_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION BP GATA3
GO_MESONEPHRIC_TUBULE_MORPHOGENESIS BP GATA3
GO_RESPONSE_TO_ESTROGEN BP GATA3
GO_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION BP GATA3
GO_POSITIVE_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION BP GATA3
GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS BP GATA3
GO_REGULATION_OF_INTERLEUKIN_13_PRODUCTION BP GATA3
GO_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION BP GATA3
GO_REGULATION_OF_CYTOKINE_SECRETION BP GATA3
GO_NEGATIVE_REGULATION_OF_INFLAMMATORY_RESPONSE BP GATA3
GO_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS BP GATA3
GO_REGULATION_OF_PROTEIN_ACETYLATION BP GATA3
GO_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION BP GATA3
GO_NEGATIVE_REGULATION_OF_EMBRYONIC_DEVELOPMENT BP GATA3
GO_POSITIVE_REGULATION_OF_CYTOKINE_SECRETION BP GATA3
GO_VENTRICULAR_SEPTUM_DEVELOPMENT BP GATA3
GO_RESPONSE_TO_ABIOTIC_STIMULUS BP GATA3
GO_CYTOKINE_SECRETION BP GATA3
GO_POSITIVE_REGULATION_OF_INTERLEUKIN_4_PRODUCTION BP GATA3
GO_ALPHA_BETA_T_CELL_ACTIVATION BP GATA3
GO_REGULATION_OF_CELL_CELL_ADHESION BP GATA3
GO_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY BP GATA3
GO_CELL_FATE_DETERMINATION BP GATA3
GO_REGULATION_OF_HISTONE_H3_K4_METHYLATION BP GATA3
GO_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING BP GATA3
GO_REGULATION_OF_CHROMATIN_ORGANIZATION BP GATA3
GO_CELL_FATE_COMMITMENT BP GATA3
GO_POSITIVE_REGULATION_OF_PROTEIN_ACETYLATION BP GATA3
GO_HEART_VALVE_DEVELOPMENT BP GATA3
GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING BP GATA3
GO_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE BP GATA3
GO_TOR_SIGNALING BP GATA3
GO_PHARYNGEAL_SYSTEM_DEVELOPMENT BP GATA3
GO_REGULATION_OF_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY BP GATA3
GO_RESPONSE_TO_GAMMA_RADIATION BP GATA3
GO_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING BP GATA3
GO_AUTONOMIC_NERVOUS_SYSTEM_DEVELOPMENT BP GATA3
GO_EPITHELIAL_CELL_MORPHOGENESIS BP GATA3
GO_SENSORY_ORGAN_DEVELOPMENT BP GATA3
GO_REGULATION_OF_INFLAMMATORY_RESPONSE BP GATA3
GO_SENSORY_ORGAN_MORPHOGENESIS BP GATA3
GO_POSITIVE_REGULATION_OF_INTERLEUKIN_13_PRODUCTION BP GATA3
GO_LYMPHOCYTE_MIGRATION BP GATA3
GO_REGULATION_OF_HORMONE_METABOLIC_PROCESS BP GATA3
GO_KIDNEY_MORPHOGENESIS BP GATA3
GO_T_CELL_MEDIATED_IMMUNITY BP GATA3
GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY BP GATA3
GO_REGULATION_OF_INTERLEUKIN_2_PRODUCTION BP GATA3
GO_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY BP GATA3
GO_NEPHRON_TUBULE_FORMATION BP GATA3
GO_RESPONSE_TO_CYTOKINE BP GATA3
GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS BP GATA3
GO_NEPHRON_DEVELOPMENT BP GATA3
GO_LYMPHOID_PROGENITOR_CELL_DIFFERENTIATION BP GATA3
GO_POSITIVE_REGULATION_OF_EMBRYONIC_DEVELOPMENT BP GATA3
GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING BP GATA3
GO_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING BP GATA3
GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION BP GATA3
GO_MESONEPHROS_DEVELOPMENT BP GATA3
GO_REGULATION_OF_CELLULAR_AMINO_ACID_METABOLIC_PROCESS BP GATA3
GO_UTERUS_DEVELOPMENT BP GATA3
GO_ENDOCRINE_PROCESS BP GATA3
GO_NEPHRIC_DUCT_MORPHOGENESIS BP GATA3
GO_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING BP GATA3
GO_POSITIVE_REGULATION_OF_MESONEPHROS_DEVELOPMENT BP GATA3
GO_T_CELL_SELECTION BP GATA3
GO_LENS_DEVELOPMENT_IN_CAMERA_TYPE_EYE BP GATA3
GO_MALE_SEX_DIFFERENTIATION BP GATA3
GO_REGULATION_OF_HISTONE_H3_K9_ACETYLATION BP GATA3
GO_INNER_EAR_MORPHOGENESIS BP GATA3
GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS BP GATA3
GO_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE BP GATA3
GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION BP GATA3
GO_TRANSCRIPTION_FACTOR_COMPLEX CC GATA3
GO_CORE_PROMOTER_BINDING MF GATA3
GO_E_BOX_BINDING MF GATA3
GO_DOUBLE_STRANDED_DNA_BINDING MF GATA3
GO_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING MF GATA3
GO_HMG_BOX_DOMAIN_BINDING MF GATA3
GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING MF GATA3
GO_GROWTH_FACTOR_RECEPTOR_BINDING MF GATA3
GO_MACROMOLECULAR_COMPLEX_BINDING MF GATA3
GO_CYTOKINE_RECEPTOR_BINDING MF GATA3

Survival analysis of GATA3



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of GATA3