Sample overview of SK-N-FI

Sample ID: Sample_02_314
Biosample type: Cell line
Tissue type: Neuroblastoma
Biosample name: SK-N-FI
Data source: NCBI GEO/SRA
GSE ID: GSE90683
Cancer type: Neuroblastoma
CRC number: 162
TF number of all CRCs: 31
TF list of all CRCs: POU3F3, RARA, TBX2, KLF7, PHOX2B, LMX1B, TFAP2B, HOXD8, ZEB1, FOXO3, KLF13, JUNB, EBF1, SP1, RFX3, TCF4, SMAD1, GATA3, GATA2, PHOX2A, ATF3, ERF, E2F2, ISL1, MEIS2, CREB1, TCF12, TCF7L2, ETV1, SIX3, NFIB

The most representative CRC of SK-N-FI
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Relationship plot of CRC model
TF number of this CRC: 13
CRC socre: 96.84615
TF list of the most representative CRC
TF name TF family Frequency of TFs
EBF1 COE 71 / 162
FOXO3 Fork_head 82 / 162
GATA3 zf-GATA 50 / 162
HOXD8 Homeobox 93 / 162
ISL1 Homeobox 36 / 162
JUNB TF_bZIP 73 / 162
KLF7 zf-C2H2 108 / 162
LMX1B Homeobox 107 / 162
PHOX2B Homeobox 107 / 162
POU3F3 Pou 162 / 162
RARA THR-like 161 / 162
TBX2 T-box 109 / 162
TFAP2B AP-2 100 / 162

All CRCs of SK-N-FI
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
POU3F3 162 / 162 Pou ENSG00000198914
RARA 161 / 162 THR-like ENSG00000131759
TBX2 109 / 162 T-box ENSG00000121068
KLF7 108 / 162 zf-C2H2 ENSG00000118263
LMX1B 107 / 162 Homeobox ENSG00000136944
PHOX2B 107 / 162 Homeobox ENSG00000109132
TFAP2B 100 / 162 AP-2 ENSG00000008196
HOXD8 93 / 162 Homeobox ENSG00000175879
ZEB1 90 / 162 zf-C2H2 ENSG00000148516
FOXO3 82 / 162 Fork_head ENSG00000118689
KLF13 80 / 162 zf-C2H2 ENSG00000169926
JUNB 73 / 162 TF_bZIP ENSG00000171223
EBF1 71 / 162 COE ENSG00000164330
SP1 69 / 162 zf-C2H2 ENSG00000185591
RFX3 54 / 162 RFX ENSG00000080298
TCF4 54 / 162 bHLH ENSG00000196628
SMAD1 52 / 162 MH1 ENSG00000170365
GATA3 50 / 162 zf-GATA ENSG00000107485
GATA2 47 / 162 zf-GATA ENSG00000179348
PHOX2A 46 / 162 Homeobox ENSG00000165462
ATF3 41 / 162 TF_bZIP ENSG00000162772
E2F2 40 / 162 E2F ENSG00000007968
ERF 40 / 162 ETS ENSG00000105722
ISL1 36 / 162 Homeobox ENSG00000016082
MEIS2 34 / 162 Homeobox ENSG00000134138
CREB1 28 / 162 TF_bZIP ENSG00000118260
TCF12 24 / 162 bHLH ENSG00000140262
TCF7L2 14 / 162 HMG ENSG00000148737
ETV1 12 / 162 NA NA
SIX3 2 / 162 Homeobox ENSG00000138083
NFIB 1 / 162 CTF/NFI ENSG00000147862

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
TCF4 41 44 85
ISL1 40 42 82
JUNB 41 52 93
SMAD1 32 60 92
TBX2 37 54 91
ERF 41 36 77
RARA 41 57 98
ZEB1 34 57 91
TFAP2B 39 54 93
MEIS2 29 56 85
GATA3 39 53 92
SIX3 28 28 56
KLF7 39 52 91
POU3F3 40 58 98
KLF13 39 51 90
HOXD8 37 53 90
NFIB 11 39 50
SP1 34 58 92
CREB1 33 47 80
LMX1B 34 52 86
EBF1 37 58 95
PHOX2B 40 54 94
GATA2 38 47 85
TCF12 25 56 81
ETV1 27 36 63
FOXO3 35 61 96
PHOX2A 37 55 92
E2F2 29 48 77
TCF7L2 26 59 85
RFX3 31 55 86
ATF3 34 49 83

Expression of TFs in all CRCs