Cancer CRCdb

TF information

TF name:	ETV1
TF family:	NA
Ensembl gene ID:	NA
Ensembl protein ID:	NA
Entrez gene ID:	NA

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of ETV1 in all biosamples

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Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_220	Cell line	Brain	BE2C_1	0.051282051282051
Sample_02_296	Cell line	Neuroblastoma	CLB-BER-Lud	0.04973221117062
Sample_02_298	Cell line	Neuroblastoma	CLB-GA	0.10958904109589
Sample_02_299	Cell line	Neuroblastoma	CLB-MA	0.062350119904077
Sample_02_310	Cell line	Neuroblastoma	SJNB8	0.039318479685452
Sample_02_311	Cell line	Neuroblastoma	SK-N-AS	0.025974025974026
Sample_02_314	Cell line	Neuroblastoma	SK-N-FI	0.074074074074074
Sample_02_316	Cell line	Neuroblastoma	CHP212	0.10989010989011
Sample_02_319	Cell line	Neuroblastoma	NB-EBc1	0.046242774566474
Sample_02_338	Cell line	Neuroblastoma	BE2	0.058823529411765

ETV1 distribution in samples’ most representative CRC

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Sample ID	Tissue type	Biosample type	Biosample name

ETV1 distribution in all CRCs

Genomic distribution of SEs associated with ETV1

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Mutation of ETV1

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Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of ETV1

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr7	13949284	13949284	T	G	exonic	ETV1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	13971147	13971147	C	T	exonic	ETV1	nonsynonymous	CESC\|1\|194\|0.00515
-	chr7	13950914	13950914	G	A	exonic	ETV1	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	13940453	13940453	A	G	exonic	ETV1	synonymous	BLCA\|1\|396\|0.00253
-	chr7	13971174	13971174	G	-	exonic	ETV1	frameshift	ACC\|1\|90\|0.01111
-	chr7	13975488	13975488	C	T	exonic	ETV1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	13971342	13971342	G	A	exonic	ETV1	nonsynonymous	HNSC\|1\|512\|0.00195
rs774904306	chr7	13975458	13975458	C	T	exonic	ETV1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	14017051	14017051	C	T	splicing	ETV1	splicing	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	14026302	14026302	G	A	exonic	ETV1	stopgain	HNSC\|1\|512\|0.00195
-	chr7	13935690	13935690	T	C	exonic	ETV1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	13946060	13946060	C	G	exonic	ETV1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	13978856	13978856	A	G	exonic	ETV1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr7	14017092	14017092	G	-	exonic	ETV1	frameshift	HNSC\|1\|512\|0.00195
-	chr7	13971290	13971290	G	C	exonic	ETV1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	13946171	13946171	G	A	exonic	ETV1	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	13940418	13940418	T	C	exonic	ETV1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	14027742	14027742	G	A	exonic	ETV1	synonymous	HNSC\|1\|512\|0.00195
-	chr7	13950874	13950874	G	A	exonic	ETV1	synonymous	ESCA\|1\|185\|0.00541
-	chr7	13971177	13971177	G	A	exonic	ETV1	nonsynonymous	ACC\|1\|90\|0.01111
-	chr7	14028311	14028311	C	T	intronic	ETV1	unknown	BLCA\|1\|396\|0.00253
-	chr7	13935631	13935631	G	A	exonic	ETV1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	14027750	14027750	T	-	exonic	ETV1	frameshift	LIHC\|1\|373\|0.00268
-	chr7	14025746	14025746	G	T	exonic	ETV1	nonsynonymous	BRCA\|1\|982\|0.00102
rs772105404	chr7	13971292	13971292	G	A	exonic	ETV1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs777866452	chr7	13971195	13971195	G	A	exonic	ETV1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	13971264	13971264	A	G	exonic	ETV1	nonsynonymous	COAD\|2\|367\|0.00545,COADREAD\|3\|489\|0.00613,READ\|1\|122\|0.00820
-	chr7	13971306	13971306	C	A	exonic	ETV1	nonsynonymous	SARC\|1\|247\|0.00405
-	chr7	13950864	13950864	C	T	exonic	ETV1	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr7	13971355	13971355	C	T	exonic	ETV1	nonsynonymous	ACC\|1\|90\|0.01111,SKCM\|1\|368\|0.00272
-	chr7	13950933	13950933	C	G	splicing	ETV1	splicing	HNSC\|1\|512\|0.00195
rs776515664	chr7	14026312	14026312	-	A	splicing	ETV1	unknown	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	13971229	13971229	G	A	exonic	ETV1	nonsynonymous	OV\|1\|469\|0.00213
-	chr7	13946113	13946113	G	A	exonic	ETV1	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr7	13971234	13971234	T	A	exonic	ETV1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	13975515	13975515	A	T	exonic	ETV1	stopgain	UCEC\|1\|248\|0.00403
-	chr7	13971177	13971177	G	-	exonic	ETV1	frameshift	ACC\|1\|90\|0.01111
-	chr7	13949273	13949273	G	C	exonic	ETV1	synonymous	LUSC\|1\|178\|0.00562
-	chr7	13940427	13940427	G	A	exonic	ETV1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	14027793	14027793	C	T	exonic	ETV1	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr7	13978849	13978849	C	T	exonic	ETV1	synonymous	BLCA\|1\|396\|0.00253
-	chr7	14017050	14017050	A	G	splicing	ETV1	splicing	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	13935510	13935510	T	C	exonic	ETV1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	13949260	13949260	C	T	exonic	ETV1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	14027729	14027729	G	T	exonic	ETV1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	13971314	13971314	C	T	exonic	ETV1	synonymous	LUSC\|1\|178\|0.00562
-	chr7	13946090	13946090	G	A	exonic	ETV1	stopgain	UCEC\|1\|248\|0.00403
-	chr7	13950864	13950864	C	-	exonic	ETV1	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs779937870	chr7	13971369	13971369	C	T	exonic	ETV1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	13971334	13971334	G	A	exonic	ETV1	nonsynonymous	SKCM\|2\|368\|0.00543
rs536563766	chr7	13935508	13935508	C	T	exonic	ETV1	nonsynonymous	SKCM\|2\|368\|0.00543
rs765227604	chr7	13949261	13949261	G	A	exonic	ETV1	synonymous	BLCA\|1\|396\|0.00253,SKCM\|1\|368\|0.00272,UCEC\|3\|248\|0.01210
rs373561573	chr7	13975371	13975371	C	T	exonic	ETV1	synonymous	HNSC\|1\|512\|0.00195
-	chr7	14026281	14026281	C	G	exonic	ETV1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	13946202	13946202	T	G	exonic	ETV1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	13935606	13935606	C	T	exonic	ETV1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	13946217	13946217	G	C	exonic	ETV1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	13978873	13978873	T	A	splicing	ETV1	splicing	BLCA\|1\|396\|0.00253
-	chr7	13971309	13971309	C	A	exonic	ETV1	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr7	13975392	13975392	G	A	exonic	ETV1	synonymous	PRAD\|1\|499\|0.00200
-	chr7	13978819	13978819	A	C	exonic	ETV1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	14027772	14027772	C	A	exonic	ETV1	nonsynonymous	UCEC\|1\|248\|0.00403
rs752431857	chr7	13971324	13971324	G	A	exonic	ETV1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	14028649	14028649	G	A	exonic	ETV1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	13978866	13978866	A	C	exonic	ETV1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	14026299	14026299	C	A	exonic	ETV1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	13975376	13975376	G	C	exonic	ETV1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	13971306	13971306	C	T	exonic	ETV1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,HNSC\|1\|512\|0.00195
-	chr7	13949277	13949277	A	T	exonic	ETV1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	13971305	13971305	A	G	exonic	ETV1	synonymous	LUAD\|2\|543\|0.00368
rs755598582	chr7	13975516	13975516	T	C	exonic	ETV1	nonsynonymous	PCPG\|1\|184\|0.00543
-	chr7	13978837	13978837	T	C	exonic	ETV1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	13971355	13971355	C	G	exonic	ETV1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	13935541	13935541	C	T	exonic	ETV1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	13971233	13971233	G	A	exonic	ETV1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,LUAD\|1\|543\|0.00184
-	chr7	13971183	13971183	C	T	exonic	ETV1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	13971341	13971341	G	T	exonic	ETV1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	13946092	13946092	C	T	exonic	ETV1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	13935499	13935499	C	T	exonic	ETV1	nonsynonymous	OV\|1\|469\|0.00213
rs748182764	chr7	13971291	13971291	C	T	exonic	ETV1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	13946127	13946127	A	G	exonic	ETV1	synonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr7	13935579	13935579	G	T	exonic	ETV1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	13971268	13971268	G	C	exonic	ETV1	nonsynonymous	THCA\|1\|504\|0.00198
-	chr7	13978872	13978872	C	G	splicing	ETV1	splicing	BLCA\|1\|396\|0.00253
-	chr7	13949310	13949310	T	C	exonic	ETV1	nonsynonymous	LUSC\|1\|178\|0.00562,TGCT\|1\|155\|0.00645
-	chr7	13949263	13949263	A	T	exonic	ETV1	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr7	14028333	14028333	C	T	intronic	ETV1	unknown	THCA\|1\|504\|0.00198
-	chr7	13971169	13971169	G	A	exonic	ETV1	synonymous	LUAD\|1\|543\|0.00184
rs748346103	chr7	13971370	13971370	G	A	exonic	ETV1	nonsynonymous	BRCA\|1\|982\|0.00102,COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|1\|248\|0.00403
-	chr7	13975358	13975358	C	A	exonic	ETV1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	13935665	13935665	G	A	exonic	ETV1	synonymous	SKCM\|1\|368\|0.00272
-	chr7	13978772	13978772	C	T	exonic	ETV1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr7	13935629	13935629	T	C	exonic	ETV1	synonymous	HNSC\|1\|512\|0.00195
-	chr7	13975476	13975476	G	C	exonic	ETV1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	13975450	13975450	G	A	exonic	ETV1	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr7	13975376	13975376	G	A	exonic	ETV1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	13971235	13971235	G	A	exonic	ETV1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	13940403	13940403	C	A	exonic	ETV1	nonsynonymous	BRCA\|2\|982\|0.00204
-	chr7	13940377	13940377	C	T	exonic	ETV1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	13949314	13949314	C	G	exonic	ETV1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	13978747	13978747	A	G	exonic	ETV1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	13946145	13946145	A	G	exonic	ETV1	synonymous	BLCA\|1\|396\|0.00253
-	chr7	13935516	13935516	G	A	exonic	ETV1	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr7	13971323	13971323	C	G	exonic	ETV1	synonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr7	14028362	14028362	C	A	intronic	ETV1	unknown	UCEC\|1\|248\|0.00403
-	chr7	13975401	13975401	G	A	exonic	ETV1	synonymous	SKCM\|1\|368\|0.00272
rs769886672	chr7	13975472	13975472	-	G	exonic	ETV1	frameshift	KIPAN\|6\|799\|0.00751,KIRC\|6\|451\|0.01330,LUAD\|3\|543\|0.00552,STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr7	13950919	13950919	G	A	exonic	ETV1	synonymous	LUAD\|1\|543\|0.00184
-	chr7	13975473	13975473	G	-	exonic	ETV1	frameshift	COAD\|3\|367\|0.00817,COADREAD\|3\|489\|0.00613,STAD\|3\|395\|0.00759,STES\|3\|395\|0.00759
rs773216548	chr7	13935563	13935563	A	G	exonic	ETV1	synonymous	HNSC\|1\|512\|0.00195
-	chr7	13949324	13949324	G	T	exonic	ETV1	synonymous	PRAD\|1\|499\|0.00200
-	chr7	14025798	14025798	G	A	exonic	ETV1	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr7	13946208	13946208	C	A	exonic	ETV1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	13975504	13975504	G	A	exonic	ETV1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	13950876	13950876	T	A	exonic	ETV1	nonsynonymous	LUSC\|1\|178\|0.00562
rs755892534	chr7	13971367	13971367	G	A	exonic	ETV1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	13949273	13949273	G	T	exonic	ETV1	synonymous	BRCA\|1\|982\|0.00102

Disease information of ETV1

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TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
ETV1	Neoplastic Processes	C04;C23	Neoplastic Process	CTD_human
ETV1	Prostatic Neoplasms	C04;C12	Neoplastic Process	CTD_human
ETV1	Malignant neoplasm of prostate	C04;C12	Neoplastic Process	CTD_human
ETV1	Ewings sarcoma	C04	Neoplastic Process	ORPHANET

Pathway associated with ETV1

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pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0001574	p38 signaling mediated by MAPKAP kinases	pid	21	107

Go term information of ETV1

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GO_term_name	GO_term_type	TF_name
GO_MUSCLE_STRUCTURE_DEVELOPMENT	BP	ETV1
GO_PERIPHERAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION	BP	ETV1
GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION	BP	ETV1
GO_CELL_PROJECTION_ORGANIZATION	BP	ETV1
GO_PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT	BP	ETV1
GO_MECHANOSENSORY_BEHAVIOR	BP	ETV1
GO_REGULATORY_REGION_NUCLEIC_ACID_BINDING	MF	ETV1
GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING	MF	ETV1

Survival analysis of ETV1

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of ETV1

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)