Sample overview of NB-EBc1

Sample ID: Sample_02_319
Biosample type: Cell line
Tissue type: Neuroblastoma
Biosample name: NB-EBc1
Data source: NCBI GEO/SRA
GSE ID: GSE90683
Cancer type: Neuroblastoma
CRC number: 173
TF number of all CRCs: 37
TF list of all CRCs: TFAP2B, RARA, PHOX2B, PBX1, GATA3, TBX2, KLF7, ESRRG, JUNB, ZNF219, PHOX2A, TLX2, MEF2D, GATA2, MEIS2, MEIS1, KLF13, NFATC4, ZBTB7B, SOX4, HES1, SHOX2, NEUROG2, FEV, CREB1, SOX12, ETV4, ZNF217, ETV3, ISL1, MNT, ATF3, PROX1, ETV1, NR2F1, SIX3, NFIB

The most representative CRC of NB-EBc1
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Relationship plot of CRC model
TF number of this CRC: 10
CRC socre: 80.6
TF list of the most representative CRC
TF name TF family Frequency of TFs
ESRRG ESR-like 61 / 173
JUNB TF_bZIP 56 / 173
KLF7 zf-C2H2 71 / 173
PBX1 Homeobox 92 / 173
PHOX2A Homeobox 55 / 173
PHOX2B Homeobox 101 / 173
RARA THR-like 123 / 173
TBX2 T-box 75 / 173
TFAP2B AP-2 129 / 173
TLX2 Homeobox 43 / 173

All CRCs of NB-EBc1
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
TFAP2B 129 / 173 AP-2 ENSG00000008196
RARA 123 / 173 THR-like ENSG00000131759
PHOX2B 101 / 173 Homeobox ENSG00000109132
PBX1 92 / 173 Homeobox ENSG00000185630
GATA3 87 / 173 zf-GATA ENSG00000107485
TBX2 75 / 173 T-box ENSG00000121068
KLF7 71 / 173 zf-C2H2 ENSG00000118263
ESRRG 61 / 173 ESR-like ENSG00000196482
ZNF219 56 / 173 zf-C2H2 ENSG00000165804
JUNB 56 / 173 TF_bZIP ENSG00000171223
PHOX2A 55 / 173 Homeobox ENSG00000165462
TLX2 43 / 173 Homeobox ENSG00000115297
MEF2D 41 / 173 SRF ENSG00000116604
GATA2 37 / 173 zf-GATA ENSG00000179348
MEIS2 34 / 173 Homeobox ENSG00000134138
MEIS1 32 / 173 Homeobox ENSG00000143995
KLF13 30 / 173 zf-C2H2 ENSG00000169926
NFATC4 29 / 173 RHD ENSG00000100968
ZBTB7B 28 / 173 ZBTB ENSG00000160685
SOX4 23 / 173 HMG ENSG00000124766
HES1 21 / 173 bHLH ENSG00000114315
SHOX2 20 / 173 Homeobox ENSG00000168779
NEUROG2 19 / 173 bHLH ENSG00000178403
FEV 17 / 173 ETS ENSG00000163497
CREB1 16 / 173 TF_bZIP ENSG00000118260
SOX12 15 / 173 HMG ENSG00000177732
ETV4 14 / 173 ETS ENSG00000175832
ZNF217 11 / 173 zf-C2H2 ENSG00000171940
ETV3 11 / 173 ETS ENSG00000117036
ISL1 11 / 173 Homeobox ENSG00000016082
MNT 11 / 173 bHLH ENSG00000070444
ATF3 10 / 173 TF_bZIP ENSG00000162772
PROX1 9 / 173 HPD ENSG00000117707
ETV1 8 / 173 NA NA
NR2F1 5 / 173 RXR-like ENSG00000175745
SIX3 2 / 173 Homeobox ENSG00000138083
NFIB 2 / 173 CTF/NFI ENSG00000147862

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
ZNF217 31 38 69
TFAP2B 41 65 106
NFATC4 26 64 90
ISL1 31 45 76
ZNF219 37 57 94
TBX2 41 58 99
SOX4 28 65 93
RARA 46 68 114
PROX1 43 28 71
SOX12 23 62 85
NR2F1 15 61 76
MEIS2 25 62 87
MEIS1 29 64 93
SIX3 38 35 73
NEUROG2 27 43 70
PBX1 41 60 101
PHOX2B 45 57 102
KLF13 34 59 93
ESRRG 36 63 99
JUNB 47 45 92
ZBTB7B 38 50 88
CREB1 37 44 81
FEV 21 52 73
SHOX2 24 50 74
PHOX2A 44 56 100
GATA2 41 53 94
GATA3 45 63 108
ETV1 30 31 61
NFIB 12 36 48
ETV3 31 32 63
MNT 42 27 69
ETV4 23 58 81
TLX2 33 60 93
KLF7 41 62 103
MEF2D 40 53 93
HES1 34 41 75
ATF3 25 43 68

Expression of TFs in all CRCs