TF information

TF name: FEV
TF family: ETS
Ensembl gene ID: ENSG00000163497
Ensembl protein ID: ENSP00000295727
Entrez gene ID: 54738
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of FEV in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_220Cell lineBrainBE2C_10.70512820512821
Sample_02_296Cell lineNeuroblastomaCLB-BER-Lud0.079571537872992
Sample_02_299Cell lineNeuroblastomaCLB-MA0.55395683453237
Sample_02_304Cell lineNeuroblastomaN2060.125
Sample_02_319Cell lineNeuroblastomaNB-EBc10.098265895953757
Sample_02_338Cell lineNeuroblastomaBE20.64705882352941

FEV distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_220BrainCell lineBE2C_1
Sample_02_299NeuroblastomaCell lineCLB-MA
Sample_02_338NeuroblastomaCell lineBE2

FEV distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with FEV
Download

Mutation of FEV
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of FEV

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr2219846752219846752AGexonicFEVsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr2219848966219848966GAexonicFEVsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr2219846735219846735TCexonicFEVnonsynonymous UCEC|1|248|0.00403
-chr2219848978219848978C-exonicFEVframeshift LUAD|1|543|0.00184
-chr2219846738219846738GAexonicFEVnonsynonymous LUAD|1|543|0.00184
-chr2219846886219846886CGexonicFEVnonsynonymous BRCA|1|982|0.00102
-chr2219846895219846895CAexonicFEVnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr2219846723219846723AGexonicFEVnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr2219846968219846968CAexonicFEVnonsynonymous UCEC|1|248|0.00403
rs767664032chr2219846688219846688CTexonicFEVnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr2219849754219849754TCexonicFEVnonsynonymous LIHC|1|373|0.00268
-chr2219846970219846970GCexonicFEVnonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr2219846816219846816TAexonicFEVnonsynonymous LUAD|4|543|0.00737
-chr2219846732219846732CTexonicFEVnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs749827919chr2219846739219846739CTexonicFEVnonsynonymous UCEC|1|248|0.00403
-chr2219846787219846787AGexonicFEVnonsynonymous UCEC|1|248|0.00403

Disease information of FEV
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
FEV Mental Depression F01 Mental or Behavioral Dysfunction PSYGENET
FEV Depressive disorder F03 Mental or Behavioral Dysfunction PSYGENET
FEV Myocardial Ischemia C14 Disease or Syndrome CTD_human
FEV Mood Disorders F03 Mental or Behavioral Dysfunction PSYGENET

Pathway associated with FEV
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0001604 PDGF signaling pathway panther 113 1684
pathway0002812 Hs_Sudden_Infant_Death_Syndrome_(SIDS)_Susceptibility_Pathways_WP706_86078 wikipathways 33 60

Go term information of FEV
GO_term_name GO_term_type TF_name
GO_NEURON_MATURATION BP FEV
GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER BP FEV
GO_NEURON_FATE_SPECIFICATION BP FEV
GO_NEURON_FATE_COMMITMENT BP FEV
GO_CELL_FATE_SPECIFICATION BP FEV
GO_SEQUENCE_SPECIFIC_DNA_BINDING MF FEV

Survival analysis of FEV



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of FEV