TF information

TF name: ESRRG
TF family: ESR-like
Ensembl gene ID: ENSG00000196482
Ensembl protein ID: ENSP00000352077, ENSP00000419594, ENSP00000354584, ENSP00000417374, ENSP00000355907, ENSP00000419155, ENSP00000355904, ENSP00000386171, ENSP00000355225, ENSP00000355905, ENSP00000419514, ENSP00000481528, ENSP00000375761, ENSP00000418629, ENSP00000353108
Entrez gene ID: 2104
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of ESRRG in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_220Cell lineBrainBE2C_10.44871794871795
Sample_02_299Cell lineNeuroblastomaCLB-MA0.19424460431655
Sample_02_302Cell lineNeuroblastomaIMR320.32142857142857
Sample_02_311Cell lineNeuroblastomaSK-N-AS0.53246753246753
Sample_02_312Cell lineNeuroblastomaSK-N-BE_2-C0.29787234042553
Sample_02_318Cell lineNeuroblastomaNB690.453125
Sample_02_319Cell lineNeuroblastomaNB-EBc10.35260115606936
Sample_02_338Cell lineNeuroblastomaBE20.52941176470588

ESRRG distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_220BrainCell lineBE2C_1
Sample_02_311NeuroblastomaCell lineSK-N-AS
Sample_02_312NeuroblastomaCell lineSK-N-BE_2-C
Sample_02_319NeuroblastomaCell lineNB-EBc1
Sample_02_338NeuroblastomaCell lineBE2

ESRRG distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with ESRRG
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Mutation of ESRRG
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of ESRRG

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr1216737663216737663CTexonicESRRGnonsynonymous BLCA|1|396|0.00253
rs866478481chr1216692670216692670GAexonicESRRGnonsynonymous SKCM|1|368|0.00272
-chr1216680433216680433CTexonicESRRGnonsynonymous SKCM|2|368|0.00543
rs562995789chr1216850740216850740CTexonicESRRGsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216680421216680421GAexonicESRRGstopgain SKCM|1|368|0.00272,UCS|1|57|0.01754
-chr1216737723216737723CGsplicingESRRGsplicing GBM|1|290|0.00345,GBMLGG|1|820|0.00122
-chr1216850491216850491GCexonicESRRGnonsynonymous LIHC|1|373|0.00268
-chr1216737622216737622TAexonicESRRGsynonymous LUAD|1|543|0.00184
-chr1216741400216741400GTexonicESRRGstopgain LUSC|1|178|0.00562
-chr1216850657216850657CTexonicESRRGnonsynonymous SKCM|1|368|0.00272
-chr1216896587216896587CGexonicESRRGnonsynonymous BRCA|1|982|0.00102
-chr1216850758216850758GTexonicESRRGsynonymous LUAD|1|543|0.00184
rs777160519chr1216824353216824353CTexonicESRRGnonsynonymous GBMLGG|2|820|0.00244,LGG|2|530|0.00377
-chr1216680448216680448CAexonicESRRGnonsynonymous PAAD|1|185|0.00541
-chr1216680423216680423CTexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216850525216850525GTexonicESRRGstopgain HNSC|1|512|0.00195
-chr1216692637216692638TA-exonicESRRGframeshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216850784216850784AGexonicESRRGnonsynonymous BLCA|1|396|0.00253
-chr1216737608216737608GAexonicESRRGnonsynonymous LUSC|1|178|0.00562,PAAD|1|185|0.00541
-chr1216850647216850647CAexonicESRRGsynonymous LUSC|1|178|0.00562
-chr1216737702216737702ATexonicESRRGnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216741435216741435GAexonicESRRGnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216692698216692698TCexonicESRRGnonsynonymous UCEC|1|248|0.00403
-chr1216850479216850479CAexonicESRRGsynonymous LUAD|1|543|0.00184
-chr1216741353216741353ATexonicESRRGnonsynonymous LIHC|1|373|0.00268
-chr1216680454216680454AGexonicESRRGnonsynonymous UCEC|1|248|0.00403
-chr1216737649216737649GTexonicESRRGsynonymous LUAD|1|543|0.00184
-chr1216850545216850545CTexonicESRRGsynonymous SKCM|1|368|0.00272
-chr1216741436216741436CGexonicESRRGsynonymous ESCA|1|185|0.00541
-chr1216850459216850459GAexonicESRRGnonsynonymous SKCM|1|368|0.00272
rs10863247chr1216692741216692741CTexonicESRRGsynonymous DLBC|1|48|0.02083
-chr1216850551216850551CTexonicESRRGsynonymous LUAD|1|543|0.00184
-chr1216850645216850645GAexonicESRRGnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216850454216850454CTexonicESRRGnonsynonymous LUSC|1|178|0.00562
-chr1216692605216692605CAexonicESRRGnonsynonymous UCEC|1|248|0.00403
-chr1216737693216737693CGexonicESRRGnonsynonymous LUSC|1|178|0.00562
-chr1216737577216737577CTexonicESRRGstopgain SKCM|2|368|0.00543
-chr1216692702216692702ACexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216850751216850751CAexonicESRRGnonsynonymous LUAD|1|543|0.00184
rs774655818chr1216824404216824404GAexonicESRRGnonsynonymous LUAD|1|543|0.00184
-chr1216680288216680288TGexonicESRRGnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216680404216680404CTexonicESRRGsynonymous BRCA|1|982|0.00102
-chr1216850767216850767CAexonicESRRGsynonymous COAD|2|367|0.00545,COADREAD|2|489|0.00409
-chr1216692521216692521GAexonicESRRGnonsynonymous SKCM|1|368|0.00272
-chr1216680330216680330TCexonicESRRGnonsynonymous UCEC|1|248|0.00403
-chr1216737739216737739GAexonicESRRGsynonymous HNSC|1|512|0.00195
-chr1216850553216850553GAexonicESRRGstopgain BLCA|1|396|0.00253
rs149827805chr1216850783216850783GAexonicESRRGnonsynonymous UCEC|1|248|0.00403
-chr1216850806216850806AGexonicESRRGsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs770002304chr1216692642216692642GAexonicESRRGsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216850481216850481CAexonicESRRGnonsynonymous BRCA|1|982|0.00102
-chr1216692733216692733ACexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216850476216850476GCexonicESRRGstopgain HNSC|1|512|0.00195
-chr1216850581216850581GAexonicESRRGsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216850597216850597CTexonicESRRGnonsynonymous LUAD|1|543|0.00184
-chr1216692559216692559TCexonicESRRGnonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr1216850421216850421GAexonicESRRGstopgain LUAD|1|543|0.00184
-chr1216850791216850798GGAATCAA-exonicESRRGframeshift KIPAN|1|799|0.00125,KIRP|1|282|0.00355
rs745321895chr1216680463216680463GAexonicESRRGsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216850596216850596CTexonicESRRGsynonymous UCEC|1|248|0.00403
-chr1216737570216737570GTexonicESRRGnonsynonymous LUAD|1|543|0.00184
-chr1216850555216850555GAexonicESRRGnonsynonymous OV|1|469|0.00213
-chr1216850620216850620GTexonicESRRGsynonymous LUAD|1|543|0.00184
-chr1216850746216850746GAexonicESRRGsynonymous HNSC|1|512|0.00195
-chr1216824354216824354GTexonicESRRGnonsynonymous LUAD|1|543|0.00184
-chr1216692714216692714ATexonicESRRGsynonymous ESCA|1|185|0.00541
-chr1216896593216896593CAexonicESRRGstopgain ESCA|1|185|0.00541
-chr1216824393216824393CTexonicESRRGnonsynonymous SKCM|1|368|0.00272
-chr1216737606216737606CTexonicESRRGnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs767510877chr1216850650216850650GAexonicESRRGsynonymous LUAD|2|543|0.00368
-chr1216692548216692548TCexonicESRRGnonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
rs753231523chr1216850768216850768GAexonicESRRGnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216680458216680458CTexonicESRRGsynonymous HNSC|1|512|0.00195
-chr1216692701216692701ACexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216692578216692578GAexonicESRRGsynonymous BLCA|1|396|0.00253
-chr1216680465216680465GTexonicESRRGnonsynonymous DLBC|1|48|0.02083
-chr1216896586216896586TCexonicESRRGnonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr1216850624216850624GAexonicESRRGnonsynonymous SKCM|1|368|0.00272
-chr1216741352216741352CAexonicESRRGsynonymous LUAD|1|543|0.00184
-chr1216692757216692757GAexonicESRRGnonsynonymous UCEC|1|248|0.00403
-chr1216850620216850620GAexonicESRRGsynonymous SKCM|1|368|0.00272
-chr1216741391216741391CAexonicESRRGnonsynonymous UCEC|1|248|0.00403
-chr1216824346216824346CAexonicESRRGnonsynonymous UCEC|1|248|0.00403
-chr1216850489216850489AGexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs771693345chr1216850524216850524CTexonicESRRGsynonymous CESC|1|194|0.00515
-chr1216680389216680389GAexonicESRRGsynonymous SKCM|1|368|0.00272
-chr1216850559216850559CAexonicESRRGnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216680338216680338TCexonicESRRGsynonymous HNSC|1|512|0.00195
-chr1216680527216680527TAsplicingESRRGsplicing LIHC|1|373|0.00268
-chr1216824331216824331CGexonicESRRGsynonymous LUAD|1|543|0.00184
-chr1216850574216850574TCexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216850617216850617CAexonicESRRGsynonymous LUAD|1|543|0.00184
-chr1216680288216680288TCexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216737588216737588TCexonicESRRGnonsynonymous LUSC|1|178|0.00562
-chr1216850615216850615C-exonicESRRGframeshift LUAD|1|543|0.00184
-chr1216737742216737742CTexonicESRRGsynonymous BRCA|1|982|0.00102
-chr1216737575216737575GAexonicESRRGnonsynonymous HNSC|2|512|0.00391
rs751537343chr1216850516216850516TCexonicESRRGnonsynonymous BRCA|1|982|0.00102
-chr1216850552216850552TAexonicESRRGnonsynonymous LUAD|1|543|0.00184
-chr1216850834216850834CTsplicingESRRGsplicing LUSC|1|178|0.00562
-chr1216741392216741392CAexonicESRRGnonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr1216692692216692692CGexonicESRRGnonsynonymous LUAD|1|543|0.00184
-chr1216680418216680418CGexonicESRRGnonsynonymous DLBC|1|48|0.02083
-chr1216737707216737707GCexonicESRRGstopgain BLCA|1|396|0.00253
rs370360195chr1216741383216741383GAexonicESRRGnonsynonymous LUAD|1|543|0.00184
-chr1216850654216850654ACexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs750331242chr1216850658216850658CTexonicESRRGnonsynonymous SKCM|1|368|0.00272
-chr1216850796216850796CTexonicESRRGnonsynonymous ESCA|1|185|0.00541
-chr1216850642216850642GAexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216850754216850754GTexonicESRRGnonsynonymous BRCA|1|982|0.00102
-chr1216692635216692635TAexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216850694216850694CTexonicESRRGnonsynonymous LIHC|1|373|0.00268
-chr1216850616216850616CTexonicESRRGnonsynonymous LUSC|1|178|0.00562
-chr1216824386216824386GTexonicESRRGnonsynonymous LUSC|1|178|0.00562
-chr1216850693216850693CAexonicESRRGnonsynonymous LUSC|1|178|0.00562
-chr1216737606216737606CAexonicESRRGnonsynonymous HNSC|1|512|0.00195
rs199995809chr1216850733216850733CTexonicESRRGnonsynonymous HNSC|1|512|0.00195
-chr1216680314216680314TCexonicESRRGsynonymous SKCM|1|368|0.00272
rs761583933chr1216850648216850648GAexonicESRRGnonsynonymous COAD|1|367|0.00272,COADREAD|2|489|0.00409,OV|1|469|0.00213,READ|1|122|0.00820
rs141125727chr1216850700216850700CTexonicESRRGnonsynonymous UCEC|1|248|0.00403
-chr1216692613216692613TCexonicESRRGnonsynonymous UVM|1|80|0.01250
-chr1216896629216896629CGexonicESRRGnonsynonymous CESC|1|194|0.00515
rs376743939chr1216850701216850701GAexonicESRRGsynonymous BLCA|1|396|0.00253
-chr1216850766216850766CGexonicESRRGnonsynonymous LUSC|1|178|0.00562
-chr1216741435216741435GTexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs773155899chr1216850763216850763GCexonicESRRGnonsynonymous LUAD|1|543|0.00184
-chr1216692542216692542CTexonicESRRGnonsynonymous SKCM|2|368|0.00543
-chr1216880805216880805CTUTR5ESRRGunknown CESC|1|194|0.00515
-chr1216680464216680464CAexonicESRRGsynonymous HNSC|1|512|0.00195
-chr1216741360216741360GTexonicESRRGnonsynonymous LUAD|1|543|0.00184
-chr1216850521216850521CTexonicESRRGnonsynonymous HNSC|1|512|0.00195
-chr1216737654216737654CTexonicESRRGnonsynonymous LIHC|1|373|0.00268
-chr1216850602216850602ATexonicESRRGsynonymous HNSC|1|512|0.00195
-chr1216850609216850609CTexonicESRRGnonsynonymous SKCM|1|368|0.00272
-chr1216850662216850662CTexonicESRRGsynonymous SKCM|1|368|0.00272
rs186770984chr1216692627216692627GAexonicESRRGsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs762615151chr1216737685216737685CTexonicESRRGsynonymous LUAD|1|543|0.00184
-chr1216741441216741441CTsplicingESRRGsplicing COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216824367216824367GAexonicESRRGsynonymous UCEC|1|248|0.00403
-chr1216850792216850792GAexonicESRRGnonsynonymous SKCM|1|368|0.00272
-chr1216850530216850530GAexonicESRRGsynonymous HNSC|2|512|0.00391
-chr1216692536216692536CGexonicESRRGnonsynonymous BLCA|1|396|0.00253
-chr1216692753216692753CTexonicESRRGsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216850613216850613CAexonicESRRGnonsynonymous LUSC|1|178|0.00562
rs780520471chr1216737574216737574CTexonicESRRGsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216824369216824369AGexonicESRRGnonsynonymous LUAD|1|543|0.00184
-chr1216850675216850675AGexonicESRRGnonsynonymous UCEC|1|248|0.00403
-chr1216737638216737638AGexonicESRRGnonsynonymous LUSC|1|178|0.00562
rs765802592chr1216896605216896605AGexonicESRRGnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216850735216850735CTexonicESRRGnonsynonymous PRAD|1|499|0.00200
-chr1216850770216850770CGexonicESRRGnonsynonymous BLCA|1|396|0.00253
-chr1216737618216737618ATexonicESRRGnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1216680401216680401CAexonicESRRGnonsynonymous UCEC|1|248|0.00403
rs777601840chr1216680424216680424GAexonicESRRGnonsynonymous SKCM|1|368|0.00272
-chr1216850442216850442CTexonicESRRGnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1216850808216850808CTexonicESRRGnonsynonymous LUAD|1|543|0.00184

Disease information of ESRRG
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source

Pathway associated with ESRRG
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0001534 Nuclear Receptor transcription pathway reactome 51 284

Go term information of ESRRG
GO_term_name GO_term_type TF_name
GO_HORMONE_MEDIATED_SIGNALING_PATHWAY BP ESRRG
GO_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY BP ESRRG
GO_TRANSCRIPTION_FACTOR_ACTIVITY_DIRECT_LIGAND_REGULATED_SEQUENCE_SPECIFIC_DNA_BINDING MF ESRRG
GO_REGULATORY_REGION_NUCLEIC_ACID_BINDING MF ESRRG
GO_STEROID_HORMONE_RECEPTOR_ACTIVITY MF ESRRG

Survival analysis of ESRRG



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of ESRRG