Sample overview of SJNB8

Sample ID: Sample_02_310
Biosample type: Cell line
Tissue type: Neuroblastoma
Biosample name: SJNB8
Data source: NCBI GEO/SRA
GSE ID: GSE90683
Cancer type: Neuroblastoma
CRC number: 1526
TF number of all CRCs: 50
TF list of all CRCs: RARA, TFAP2B, MEIS1, TBX2, PHOX2B, SP1, KLF7, SMAD3, TEAD1, MAZ, MEIS2, GATA3, PBX1, JUNB, JUND, KLF16, EBF1, TLX2, DLX2, PHOX2A, TCF12, SOX4, RFX3, RFX7, MEF2D, NFE2L2, ZNF219, ZBTB7B, TCF4, NR6A1, ERF, RFX5, NEUROD1, ISL1, SOX12, NFYA, NR2F1, ZNF423, ETV4, ZNF217, ETV1, SATB1, HMBOX1, SOX2, PROX1, NFE2L1, CREB3L2, HLX, NHLH1, NFIB

The most representative CRC of SJNB8
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Relationship plot of CRC model
TF number of this CRC: 13
CRC socre: 735.7692
TF list of the most representative CRC
TF name TF family Frequency of TFs
DLX2 Homeobox 377 / 1526
KLF7 zf-C2H2 650 / 1526
MAZ zf-C2H2 616 / 1526
MEIS1 Homeobox 890 / 1526
MEIS2 Homeobox 573 / 1526
PBX1 Homeobox 542 / 1526
PHOX2B Homeobox 674 / 1526
RARA THR-like 1487 / 1526
SMAD3 MH1 633 / 1526
SP1 zf-C2H2 669 / 1526
TBX2 T-box 729 / 1526
TEAD1 TEA 630 / 1526
TFAP2B AP-2 1095 / 1526

All CRCs of SJNB8
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
RARA 1487 / 1526 THR-like ENSG00000131759
TFAP2B 1095 / 1526 AP-2 ENSG00000008196
MEIS1 890 / 1526 Homeobox ENSG00000143995
TBX2 729 / 1526 T-box ENSG00000121068
PHOX2B 674 / 1526 Homeobox ENSG00000109132
SP1 669 / 1526 zf-C2H2 ENSG00000185591
KLF7 650 / 1526 zf-C2H2 ENSG00000118263
SMAD3 633 / 1526 MH1 ENSG00000166949
TEAD1 630 / 1526 TEA ENSG00000187079
MAZ 616 / 1526 zf-C2H2 ENSG00000103495
MEIS2 573 / 1526 Homeobox ENSG00000134138
GATA3 571 / 1526 zf-GATA ENSG00000107485
PBX1 542 / 1526 Homeobox ENSG00000185630
JUNB 524 / 1526 TF_bZIP ENSG00000171223
JUND 522 / 1526 TF_bZIP ENSG00000130522
KLF16 435 / 1526 zf-C2H2 ENSG00000129911
EBF1 413 / 1526 COE ENSG00000164330
TLX2 387 / 1526 Homeobox ENSG00000115297
DLX2 377 / 1526 Homeobox ENSG00000115844
PHOX2A 363 / 1526 Homeobox ENSG00000165462
TCF12 297 / 1526 bHLH ENSG00000140262
SOX4 269 / 1526 HMG ENSG00000124766
RFX3 267 / 1526 RFX ENSG00000080298
RFX7 221 / 1526 RFX ENSG00000181827
MEF2D 214 / 1526 SRF ENSG00000116604
NFE2L2 214 / 1526 TF_bZIP ENSG00000116044
ZNF219 209 / 1526 zf-C2H2 ENSG00000165804
ZBTB7B 208 / 1526 ZBTB ENSG00000160685
TCF4 188 / 1526 bHLH ENSG00000196628
NR6A1 162 / 1526 GCNF-like ENSG00000148200
ERF 161 / 1526 ETS ENSG00000105722
RFX5 140 / 1526 RFX ENSG00000143390
NEUROD1 126 / 1526 bHLH ENSG00000162992
ISL1 100 / 1526 Homeobox ENSG00000016082
SOX12 98 / 1526 HMG ENSG00000177732
NFYA 96 / 1526 NF-YA ENSG00000001167
NR2F1 85 / 1526 RXR-like ENSG00000175745
ZNF423 74 / 1526 zf-C2H2 ENSG00000102935
ETV4 69 / 1526 ETS ENSG00000175832
ZNF217 68 / 1526 zf-C2H2 ENSG00000171940
ETV1 60 / 1526 NA NA
SATB1 56 / 1526 CUT ENSG00000182568
HMBOX1 47 / 1526 Homeobox ENSG00000147421
SOX2 40 / 1526 HMG ENSG00000181449
PROX1 30 / 1526 HPD ENSG00000117707
NFE2L1 23 / 1526 TF_bZIP ENSG00000082641
CREB3L2 17 / 1526 TF_bZIP ENSG00000182158
HLX 8 / 1526 Homeobox ENSG00000136630
NHLH1 6 / 1526 bHLH ENSG00000171786
NFIB 1 / 1526 CTF/NFI ENSG00000147862

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
ZNF217 48 39 87
TCF4 59 52 111
PHOX2B 60 61 121
ISL1 50 47 97
JUNB 60 58 118
ZNF219 42 71 113
JUND 51 71 122
SMAD3 48 76 124
TBX2 53 61 114
NFYA 39 62 101
MAZ 50 79 129
SOX2 24 78 102
TEAD1 55 69 124
MEF2D 52 61 113
SOX4 42 75 117
RARA 59 79 138
KLF16 51 72 123
HMBOX1 35 59 94
SOX12 40 75 115
TFAP2B 55 68 123
NR2F1 37 66 103
MEIS2 53 64 117
MEIS1 57 69 126
GATA3 58 70 128
KLF7 51 69 120
ERF 58 43 101
ZNF423 55 36 91
ZBTB7B 47 61 108
SP1 49 79 128
TCF12 43 70 113
NR6A1 33 66 99
SATB1 42 63 105
PHOX2A 56 63 119
PROX1 53 32 85
PBX1 50 70 120
ETV1 44 38 82
NFIB 16 40 56
NEUROD1 31 62 93
ETV4 32 63 95
HLX 20 58 78
RFX5 41 60 101
RFX7 42 60 102
TLX2 46 72 118
RFX3 44 65 109
CREB3L2 38 38 76
NHLH1 14 66 80
DLX2 56 57 113
NFE2L2 43 64 107
EBF1 46 66 112
NFE2L1 45 39 84

Expression of TFs in all CRCs