Cancer CRCdb

Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_310	Cell line	Neuroblastoma	SJNB8	0.091743119266055
Sample_02_404	Cell line	Mammary Gland	ZR-75-1_2	0.21223021582734

Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of RFX5

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
rs745673103	chr1	151315111	151315111	G	A	exonic	RFX5	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs755766544	chr1	151316936	151316936	G	A	exonic	RFX5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr1	151314816	151314816	C	A	exonic	RFX5	nonsynonymous	LIHC\|1\|373\|0.00268
rs766158684	chr1	151315315	151315315	G	A	exonic	RFX5	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr1	151316209	151316209	G	A	exonic	RFX5	synonymous	BLCA\|1\|396\|0.00253,LUAD\|1\|543\|0.00184
-	chr1	151316207	151316207	A	G	exonic	RFX5	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr1	151317225	151317225	T	A	exonic	RFX5	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr1	151314685	151314685	C	T	exonic	RFX5	nonsynonymous	BLCA\|2\|396\|0.00505,OV\|1\|469\|0.00213
-	chr1	151316744	151316744	T	A	exonic	RFX5	nonsynonymous	BRCA\|1\|982\|0.00102
rs778840668	chr1	151316245	151316245	G	A	exonic	RFX5	synonymous	SKCM\|1\|368\|0.00272
-	chr1	151314893	151314893	G	A	exonic	RFX5	synonymous	SKCM\|1\|368\|0.00272
rs377555466	chr1	151316983	151316983	C	T	exonic	RFX5	nonsynonymous	ESCA\|1\|185\|0.00541
rs767055616	chr1	151316714	151316714	T	C	exonic	RFX5	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr1	151318753	151318753	C	-	exonic	RFX5	frameshift	LIHC\|1\|373\|0.00268,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr1	151315082	151315082	C	T	exonic	RFX5	synonymous	LIHC\|1\|373\|0.00268
rs377016578	chr1	151315400	151315400	G	A	exonic	RFX5	synonymous	OV\|1\|469\|0.00213
-	chr1	151316921	151316921	G	A	exonic	RFX5	stopgain	UCEC\|1\|248\|0.00403
-	chr1	151316215	151316215	C	T	exonic	RFX5	synonymous	PRAD\|1\|499\|0.00200
-	chr1	151317606	151317606	G	A	exonic	RFX5	nonsynonymous	CESC\|1\|194\|0.00515
-	chr1	151316350	151316350	C	T	exonic	RFX5	nonsynonymous	THCA\|1\|504\|0.00198
-	chr1	151317012	151317012	C	A	exonic	RFX5	synonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr1	151316349	151316349	C	A	exonic	RFX5	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr1	151315125	151315125	T	G	exonic	RFX5	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr1	151317625	151317625	G	T	exonic	RFX5	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr1	151317006	151317006	G	T	exonic	RFX5	stopgain	UCEC\|1\|248\|0.00403
-	chr1	151315211	151315211	A	-	exonic	RFX5	frameshift	BLCA\|1\|396\|0.00253
-	chr1	151315026	151315026	G	C	exonic	RFX5	stopgain	HNSC\|2\|512\|0.00391
-	chr1	151315095	151315095	G	C	exonic	RFX5	stopgain	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
rs778751859	chr1	151315110	151315110	C	T	exonic	RFX5	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr1	151317258	151317258	A	G	exonic	RFX5	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr1	151314991	151314991	C	T	exonic	RFX5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr1	151316173	151316173	C	T	exonic	RFX5	synonymous	LUAD\|1\|543\|0.00184
-	chr1	151314684	151314684	T	C	exonic	RFX5	nonsynonymous	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409
-	chr1	151314724	151314724	C	T	exonic	RFX5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr1	151315023	151315023	C	A	exonic	RFX5	nonsynonymous	THYM\|1\|123\|0.00813
-	chr1	151317583	151317583	T	-	exonic	RFX5	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr1	151318694	151318694	G	A	exonic	RFX5	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr1	151318748	151318748	C	G	exonic	RFX5	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr1	151315446	151315446	G	T	exonic	RFX5	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr1	151315062	151315062	A	-	exonic	RFX5	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr1	151314850	151314850	C	T	exonic	RFX5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr1	151317305	151317305	C	A	exonic	RFX5	synonymous	HNSC\|1\|512\|0.00195
-	chr1	151314667	151314667	G	T	exonic	RFX5	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr1	151314788	151314788	-	T	exonic	RFX5	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr1	151315145	151315145	C	A	exonic	RFX5	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr1	151315450	151315450	G	T	exonic	RFX5	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr1	151314798	151314798	C	T	exonic	RFX5	nonsynonymous	LUAD\|1\|543\|0.00184
rs774928260	chr1	151316273	151316273	C	T	exonic	RFX5	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr1	151314770	151314770	T	C	exonic	RFX5	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs150072792	chr1	151314825	151314825	G	A	exonic	RFX5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr1	151315152	151315152	T	C	exonic	RFX5	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr1	151315510	151315510	G	-	exonic	RFX5	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr1	151314729	151314729	A	T	exonic	RFX5	stopgain	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs374354196	chr1	151315599	151315599	C	T	exonic	RFX5	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr1	151314765	151314765	C	T	exonic	RFX5	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr1	151318741	151318741	G	-	exonic	RFX5	frameshift	COAD\|7\|367\|0.01907,COADREAD\|7\|489\|0.01431,PAAD\|2\|185\|0.01081,STAD\|5\|395\|0.01266,STES\|5\|395\|0.01266
-	chr1	151314915	151314915	C	T	exonic	RFX5	nonsynonymous	BRCA\|1\|982\|0.00102
rs771641554	chr1	151318681	151318681	G	A	exonic	RFX5	nonsynonymous	BLCA\|1\|396\|0.00253,UCEC\|1\|248\|0.00403
-	chr1	151315417	151315417	G	T	exonic	RFX5	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr1	151316211	151316211	G	T	exonic	RFX5	nonsynonymous	HNSC\|1\|512\|0.00195
rs372560621	chr1	151315328	151315328	T	C	exonic	RFX5	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr1	151314930	151314930	G	A	exonic	RFX5	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs745851232	chr1	151316257	151316257	G	A	exonic	RFX5	synonymous	SKCM\|1\|368\|0.00272
-	chr1	151315507	151315507	C	T	exonic	RFX5	nonsynonymous	UCEC\|1\|248\|0.00403
rs79106593	chr1	151315105	151315105	G	T	exonic	RFX5	synonymous	HNSC\|1\|512\|0.00195
-	chr1	151316303	151316303	G	A	exonic	RFX5	nonsynonymous	PRAD\|1\|499\|0.00200,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr1	151315569	151315569	G	-	exonic	RFX5	frameshift	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409
-	chr1	151318680	151318680	C	T	splicing	RFX5	splicing	ESCA\|1\|185\|0.00541
rs764561345	chr1	151318690	151318690	C	T	exonic	RFX5	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr1	151318403	151318403	C	T	splicing	RFX5	splicing	UCEC\|1\|248\|0.00403
-	chr1	151316355	151316355	C	T	exonic	RFX5	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr1	151316295	151316295	G	-	exonic	RFX5	stopgain	LUAD\|1\|543\|0.00184
-	chr1	151318730	151318730	C	G	exonic	RFX5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr1	151314865	151314865	G	A	exonic	RFX5	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr1	151315361	151315361	G	T	exonic	RFX5	synonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr1	151316755	151316755	C	G	splicing	RFX5	splicing	LUAD\|1\|543\|0.00184
-	chr1	151316903	151316903	C	T	exonic	RFX5	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr1	151315565	151315565	-	C	exonic	RFX5	frameshift	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr1	151314837	151314837	G	A	exonic	RFX5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr1	151316199	151316199	G	A	exonic	RFX5	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr1	151316355	151316355	C	A	exonic	RFX5	stopgain	PAAD\|1\|185\|0.00541
-	chr1	151314838	151314838	G	A	exonic	RFX5	nonsynonymous	SKCM\|1\|368\|0.00272
rs559709373	chr1	151316236	151316236	G	A	exonic	RFX5	synonymous	CESC\|1\|194\|0.00515
-	chr1	151315884	151315884	A	G	exonic	RFX5	synonymous	SKCM\|1\|368\|0.00272
-	chr1	151315454	151315454	G	-	exonic	RFX5	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr1	151314894	151314894	G	A	exonic	RFX5	nonsynonymous	SKCM\|1\|368\|0.00272
rs750713961	chr1	151317291	151317291	T	C	exonic	RFX5	nonsynonymous	LUAD\|1\|543\|0.00184
rs758904746	chr1	151318740	151318740	-	G	exonic	RFX5	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr1	151315473	151315473	G	T	exonic	RFX5	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs764649554	chr1	151315600	151315600	G	A	exonic	RFX5	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr1	151314767	151314767	C	T	exonic	RFX5	synonymous	LUAD\|1\|543\|0.00184
-	chr1	151314705	151314705	G	A	exonic	RFX5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr1	151315475	151315475	G	T	exonic	RFX5	synonymous	CESC\|1\|194\|0.00515
-	chr1	151315112	151315112	C	-	exonic	RFX5	frameshift	LUAD\|1\|543\|0.00184
-	chr1	151318730	151318730	C	T	exonic	RFX5	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr1	151315436	151315436	G	A	exonic	RFX5	synonymous	SKCM\|2\|368\|0.00543
-	chr1	151316269	151316269	G	A	exonic	RFX5	synonymous	SKCM\|1\|368\|0.00272
-	chr1	151315256	151315256	T	C	exonic	RFX5	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253

TF name:	RFX5
TF family:	RFX
Ensembl gene ID:	ENSG00000143390
Ensembl protein ID:	ENSP00000376502, ENSP00000357864, ENSP00000390769, ENSP00000398666, ENSP00000409187, ENSP00000290524, ENSP00000389130, ENSP00000399095, ENSP00000387618
Entrez gene ID:	5993

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
RFX5	Bare Lymphocyte Syndrome, Type II, Complementation Group A	C16;C18;C20	Disease or Syndrome	UNIPROT
RFX5	Bare Lymphocyte Syndrome, Type II, Complementation Group B	C16;C18;C20	Disease or Syndrome	UNIPROT
RFX5	Bare Lymphocyte Syndrome, Type II, Complementation Group C	C16;C18;C20	Disease or Syndrome	UNIPROT
RFX5	Bare Lymphocyte Syndrome, Type II, Complementation Group D	C16;C18;C20	Disease or Syndrome	UNIPROT
RFX5	Bare Lymphocyte Syndrome, Type II, Complementation Group E	C16;C18;C20	Disease or Syndrome	UNIPROT
RFX5	Bare lymphocyte syndrome 2	C16;C18;C20	Disease or Syndrome	CTD_human;ORPHANET;UNIPROT

TF information

TCGA somatic mutations and clinical variants of RFX5

Survival analysis of RFX5

Expression of RFX5