TF information

TF name: NFYA
TF family: NF-YA
Ensembl gene ID: ENSG00000001167
Ensembl protein ID: ENSP00000229418, ENSP00000345702
Entrez gene ID: 4800
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of NFYA in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_219Cell lineMammary GlandMDA-MB-2310.1078431372549
Sample_02_310Cell lineNeuroblastomaSJNB80.062909567496723
Sample_02_354Cell lineColonColo2050.09009009009009

NFYA distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_219Mammary GlandCell lineMDA-MB-231
Sample_02_354ColonCell lineColo205

NFYA distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with NFYA
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Mutation of NFYA
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of NFYA

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr64106065841060658CAexonicNFYAnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr64105187641051876GAexonicNFYAnonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr64106081841060818GTexonicNFYAnonsynonymous UCEC|1|248|0.00403
rs576540807chr64106081241060812AGexonicNFYAsynonymous LUAD|1|543|0.00184
-chr64106513841065138CAexonicNFYAsynonymous UCEC|1|248|0.00403
-chr64106219541062195CTexonicNFYAstopgain PRAD|1|499|0.00200
rs747719395chr64106075741060757GAexonicNFYAnonsynonymous UCEC|1|248|0.00403
-chr64106075141060751AGexonicNFYAnonsynonymous DLBC|1|48|0.02083
-chr64106511941065119ACexonicNFYAnonsynonymous UCEC|1|248|0.00403
-chr64105935441059354CGexonicNFYAnonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr64105183741051837CTexonicNFYAnonsynonymous BLCA|1|396|0.00253
-chr64106219641062196GAexonicNFYAnonsynonymous UCEC|2|248|0.00806
-chr64105737841057378GAexonicNFYAnonsynonymous LUSC|1|178|0.00562
-chr64106076741060767GCexonicNFYAnonsynonymous CESC|1|194|0.00515
-chr64105942241059422GAexonicNFYAnonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
rs372824683chr64106078041060780CTexonicNFYAstopgain UCEC|1|248|0.00403
-chr64106219741062197ATexonicNFYAsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr64106079141060791AGexonicNFYAsynonymous ACC|1|90|0.01111
-chr64106511441065114GAexonicNFYAnonsynonymous CESC|1|194|0.00515
-chr64105182741051827CAexonicNFYAnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr64106070841060708GAexonicNFYAnonsynonymous CESC|1|194|0.00515
-chr64105804441058044GTexonicNFYAnonsynonymous LUAD|1|543|0.00184
-chr64105740441057404CTexonicNFYAsynonymous BLCA|1|396|0.00253
rs377013862chr64106511041065110CTexonicNFYAsynonymous HNSC|1|512|0.00195
rs774868192chr64106217441062174CTexonicNFYAnonsynonymous UCEC|1|248|0.00403
-chr64105738841057388GTexonicNFYAnonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr64106214141062141CTexonicNFYAsynonymous LUAD|1|543|0.00184
-chr64105940641059406-TGGTCAAexonicNFYAframeshift GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr64105178941051789ATexonicNFYAnonsynonymous SKCM|1|368|0.00272
-chr64105742641057426GAexonicNFYAnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr64105741041057410CGexonicNFYAnonsynonymous ACC|1|90|0.01111
-chr64106218041062180CTexonicNFYAnonsynonymous UCEC|1|248|0.00403
-chr64105936841059368CTexonicNFYAstopgain BLCA|1|396|0.00253
-chr64104854941048549GTsplicingNFYAsplicing UCEC|1|248|0.00403
-chr64105183241051832CGexonicNFYAnonsynonymous LIHC|1|373|0.00268
-chr64104690041046900GTexonicNFYAnonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr64105733741057337GAexonicNFYAnonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr64105943141059431AGexonicNFYAnonsynonymous SKCM|1|368|0.00272
rs771405179chr64104859441048594GAexonicNFYAsynonymous LIHC|1|373|0.00268
-chr64106510541065105-AexonicNFYAframeshift LIHC|1|373|0.00268
-chr64105927841059278-TexonicNFYAframeshift ESCA|1|185|0.00541

Disease information of NFYA
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
NFYA Lung Neoplasms C04;C08 Neoplastic Process CTD_human
NFYA Malignant neoplasm of lung C04;C08 Neoplastic Process CTD_human

Pathway associated with NFYA
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0000069 Activation of gene expression by SREBF (SREBP) reactome 42 266
pathway0000230 ATF4 activates genes reactome 25 112
pathway0000231 ATF6-alpha activates chaperone genes reactome 10 27
pathway0002391 Validated targets of C-MYC transcriptional repression pid 63 385
pathway0002601 Antigen processing and presentation kegg 75 466

Go term information of NFYA
GO_term_name GO_term_type TF_name
GO_TRANSCRIPTION_FACTOR_COMPLEX CC NFYA
GO_CORE_PROMOTER_BINDING MF NFYA
GO_TRANSCRIPTION_COFACTOR_BINDING MF NFYA
GO_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING MF NFYA

Survival analysis of NFYA



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of NFYA