1. TF detail

TF information

TF name: JUND
TF family: TF_bZIP
Ensembl gene ID: ENSG00000130522
Ensembl protein ID: ENSP00000252818, ENSP00000475153
Entrez gene ID: 3727
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:
Frequency of JUND in all biosamples
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Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_007OtherCervicalcervical-cancer_vector0.42715231788079
Sample_02_021Cell lineColonV4290.33698472182185
Sample_02_095Cell lineMammary GlandMDA-MB-4680.81284046692607
Sample_02_114Cell lineMammary GlandCAL510.92964824120603
Sample_02_115Cell lineMammary GlandMCF-70.6
Sample_02_168Cell lineProstateLNCaP0.39543726235741
Sample_02_182Cell lineHuman melanomaLOX-IMVI0.64942528735632
Sample_02_205TissueStomachGastric_Primary_Sample_T0.6962962962963
Sample_02_219Cell lineMammary GlandMDA-MB-2311
Sample_02_236Cell lineColonV2060.3064182194617
Sample_02_237Cell lineColonV3890.43511871893981
Sample_02_242Cell lineColonV4810.12907774145998
Sample_02_254Cell lineNeuroblastomaIMR5-750.41176470588235
Sample_02_280Cell lineMammary GlandSUM159_DMSO_24h0.7
Sample_02_296Cell lineNeuroblastomaCLB-BER-Lud0.45906656465187
Sample_02_307Cell lineNeuroblastomaSJNB120.56338028169014
Sample_02_308Cell lineNeuroblastomaSJNB10.53125
Sample_02_309Cell lineNeuroblastomaSJNB60.5781990521327
Sample_02_310Cell lineNeuroblastomaSJNB80.34207077326343
Sample_02_313Cell lineNeuroblastomaSK-N-DZ0.67567567567568
Sample_02_323Cell lineColonRKO1
Sample_02_359Cell lineColonColo7410.21686746987952
Sample_02_413TissueBrainGBM_24930.31318681318681
JUND distribution in samples’ most representative CRC
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Sample ID Tissue type Biosample type Biosample name
Sample_02_007CervicalOthercervical-cancer_vector
Sample_02_095Mammary GlandCell lineMDA-MB-468
Sample_02_114Mammary GlandCell lineCAL51
Sample_02_182Human melanomaCell lineLOX-IMVI
Sample_02_205StomachTissueGastric_Primary_Sample_T
Sample_02_219Mammary GlandCell lineMDA-MB-231
Sample_02_280Mammary GlandCell lineSUM159_DMSO_24h
Sample_02_307NeuroblastomaCell lineSJNB12
Sample_02_308NeuroblastomaCell lineSJNB1
Sample_02_309NeuroblastomaCell lineSJNB6
Sample_02_313NeuroblastomaCell lineSK-N-DZ
Sample_02_323ColonCell lineRKO
JUND distribution in all CRCs
Biosample type
Biosample name
Sample ID
Genomic distribution of SEs associated with JUND
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Mutation of JUND
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Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of JUND

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr191839151918391519GCexonicJUNDnonsynonymous BLCA|1|396|0.00253
rs775119898chr191839192618391926GAexonicJUNDsynonymous CESC|1|194|0.00515
rs751981092chr191839185918391859CTexonicJUNDnonsynonymous LIHC|1|373|0.00268
-chr191839138618391386GCexonicJUNDsynonymous BLCA|1|396|0.00253
-chr191839143918391439GAexonicJUNDnonsynonymous CESC|1|194|0.00515
-chr191839140918391409GAexonicJUNDsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr191839189618391896CAexonicJUNDnonsynonymous PRAD|1|499|0.00200
-chr191839146318391463TCexonicJUNDnonsynonymous SKCM|1|368|0.00272
-chr191839164118391641TAexonicJUNDnonsynonymous LUAD|1|543|0.00184
rs367728832chr191839154318391543CTexonicJUNDnonsynonymous LUSC|1|178|0.00562
-chr191839191418391914CTexonicJUNDsynonymous HNSC|1|512|0.00195
-chr191839157118391571CTexonicJUNDnonsynonymous BLCA|1|396|0.00253
-chr191839129118391291CTexonicJUNDnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr191839129718391297TCexonicJUNDnonsynonymous PRAD|2|499|0.00401
-chr191839190518391905GTexonicJUNDsynonymous SKCM|1|368|0.00272
-chr191839150518391505CAexonicJUNDnonsynonymous CESC|1|194|0.00515
-chr191839193318391933GAexonicJUNDnonsynonymous LUSC|1|178|0.00562
-chr191839190218391902GAexonicJUNDsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr191839137518391375TCexonicJUNDnonsynonymous PAAD|1|185|0.00541
-chr191839187518391875GTexonicJUNDnonsynonymous CESC|1|194|0.00515
-chr191839149418391494CAexonicJUNDnonsynonymous HNSC|1|512|0.00195
-chr191839186518391865GTexonicJUNDnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
Disease information of JUND
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TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
JUND Cocaine Abuse C25;F03 Mental or Behavioral Dysfunction CTD_human
JUND Glomerulonephritis C12;C13 Disease or Syndrome CTD_human
JUND Liver Cirrhosis C06 Disease or Syndrome CTD_human
JUND Lung Neoplasms C04;C08 Neoplastic Process CTD_human
JUND Status Epilepticus C10;C23 Disease or Syndrome CTD_human
JUND Cocaine-Related Disorders C25;F03 Mental or Behavioral Dysfunction CTD_human
JUND Fibrosis, Liver C06 Disease or Syndrome CTD_human
JUND Malignant neoplasm of lung C04;C08 Neoplastic Process CTD_human
JUND Petit mal status C10;C23 Disease or Syndrome CTD_human
JUND Grand Mal Status Epilepticus C10;C23 Disease or Syndrome CTD_human
JUND Complex Partial Status Epilepticus C10;C23 Disease or Syndrome CTD_human
JUND Cocaine Dependence C25;F03 Mental or Behavioral Dysfunction CTD_human
JUND Status Epilepticus, Subclinical C10;C23 Disease or Syndrome CTD_human
JUND Non-Convulsive Status Epilepticus C10;C23 Disease or Syndrome CTD_human
JUND Simple Partial Status Epilepticus C10;C23 Disease or Syndrome CTD_human
JUND Bright Disease C12;C13 Disease or Syndrome CTD_human
JUND AMYOTROPHIC LATERAL SCLEROSIS 1 C10;C18 Disease or Syndrome CTD_human
JUND Amyotrophic Lateral Sclerosis, Sporadic C10;C18 Disease or Syndrome CTD_human
Pathway associated with JUND
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pathway_ID pathway_name pathway_source gene_number edge_number
pathway0000187 AP-1 transcription factor network pid 71 659
pathway0000229 ATF-2 transcription factor network pid 59 451
pathway0001606 PDGFR-beta signaling pathway pid 125 2449
pathway0002392 Validated transcriptional targets of AP1 family members Fra1 and Fra2 pid 37 165
pathway0002696 Hs_Apoptosis-related_network_due_to_altered_Notch3_in_ovarian_cancer_WP2864_79278 wikipathways 51 206
pathway0002760 Hs_Oncostatin_M_Signaling_Pathway_WP2374_73668 wikipathways 44 408
pathway0002866 Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 wikipathways 107 1336
Go term information of JUND
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GO_term_name GO_term_type TF_name
GO_RESPONSE_TO_ORGANOPHOSPHORUS BP JUND
GO_AGING BP JUND
GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS BP JUND
GO_REGULATION_OF_CELL_CYCLE BP JUND
GO_CELLULAR_RESPONSE_TO_CALCIUM_ION BP JUND
GO_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION BP JUND
GO_OSTEOBLAST_DEVELOPMENT BP JUND
GO_RESPONSE_TO_PURINE_CONTAINING_COMPOUND BP JUND
GO_POSITIVE_REGULATION_OF_OSSIFICATION BP JUND
GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY_SEQUENCE_SPECIFIC_DNA_BINDING MF JUND
GO_LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_BINDING MF JUND

Survival analysis of JUND


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of JUND

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)