Sample overview of V206

Sample ID: Sample_02_236
Biosample type: Cell line
Tissue type: Colon
Biosample name: V206
Data source: NCBI GEO/SRA
GSE ID: GSE77737
Cancer type: colorectal cancer
CRC number: 483
TF number of all CRCs: 42
TF list of all CRCs: RREB1, KLF5, HNF1A, ELF3, NFE2L2, SREBF1, MEF2A, MYC, EHF, IRF2, RFX2, FOXD2, FOXP1, TCF7L2, CDX2, MECOM, MAX, TGIF1, NR4A2, FOSL2, KLF3, BHLHE40, MYB, KLF4, JUND, FOS, ATF3, NR4A1, ETS2, VDR, HES1, JUNB, CEBPA, SP3, ZNF219, ELF1, ZBTB7A, ZNF217, GATA6, ZIC2, CEBPG, MNT

The most representative CRC of V206
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Relationship plot of CRC model
TF number of this CRC: 20
CRC socre: 319.6
TF list of the most representative CRC
TF name TF family Frequency of TFs
BHLHE40 bHLH 179 / 483
CDX2 Homeobox 271 / 483
EHF ETS 331 / 483
ELF3 ETS 419 / 483
FOXD2 Fork_head 293 / 483
FOXP1 Fork_head 290 / 483
HNF1A Homeobox 442 / 483
IRF2 IRF 317 / 483
KLF4 zf-C2H2 148 / 483
KLF5 zf-C2H2 483 / 483
MAX bHLH 246 / 483
MECOM zf-C2H2 259 / 483
MEF2A SRF 348 / 483
MYC bHLH 342 / 483
NFE2L2 TF_bZIP 391 / 483
NR4A2 NGFIB-like 209 / 483
RFX2 RFX 316 / 483
RREB1 zf-C2H2 483 / 483
SREBF1 bHLH 390 / 483
TGIF1 Homeobox 235 / 483

All CRCs of V206
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
RREB1 483 / 483 zf-C2H2 ENSG00000124782
KLF5 483 / 483 zf-C2H2 ENSG00000102554
HNF1A 442 / 483 Homeobox ENSG00000135100
ELF3 419 / 483 ETS ENSG00000163435
NFE2L2 391 / 483 TF_bZIP ENSG00000116044
SREBF1 390 / 483 bHLH ENSG00000072310
MEF2A 348 / 483 SRF ENSG00000068305
MYC 342 / 483 bHLH ENSG00000136997
EHF 331 / 483 ETS ENSG00000135373
IRF2 317 / 483 IRF ENSG00000168310
RFX2 316 / 483 RFX ENSG00000087903
FOXD2 293 / 483 Fork_head ENSG00000186564
FOXP1 290 / 483 Fork_head ENSG00000114861
TCF7L2 288 / 483 HMG ENSG00000148737
CDX2 271 / 483 Homeobox ENSG00000165556
MECOM 259 / 483 zf-C2H2 ENSG00000085276
MAX 246 / 483 bHLH ENSG00000125952
TGIF1 235 / 483 Homeobox ENSG00000177426
NR4A2 209 / 483 NGFIB-like ENSG00000153234
FOSL2 206 / 483 TF_bZIP ENSG00000075426
KLF3 186 / 483 zf-C2H2 ENSG00000109787
BHLHE40 179 / 483 bHLH ENSG00000134107
MYB 169 / 483 MYB ENSG00000118513
JUND 148 / 483 TF_bZIP ENSG00000130522
KLF4 148 / 483 zf-C2H2 ENSG00000136826
FOS 141 / 483 TF_bZIP ENSG00000170345
ATF3 131 / 483 TF_bZIP ENSG00000162772
NR4A1 119 / 483 NGFIB-like ENSG00000123358
ETS2 103 / 483 ETS ENSG00000157557
VDR 96 / 483 THR-like ENSG00000111424
HES1 91 / 483 bHLH ENSG00000114315
JUNB 90 / 483 TF_bZIP ENSG00000171223
CEBPA 86 / 483 TF_bZIP ENSG00000245848
SP3 69 / 483 zf-C2H2 ENSG00000172845
ZNF219 64 / 483 zf-C2H2 ENSG00000165804
ELF1 63 / 483 ETS ENSG00000120690
ZBTB7A 59 / 483 ZBTB ENSG00000178951
ZNF217 41 / 483 zf-C2H2 ENSG00000171940
GATA6 41 / 483 zf-GATA ENSG00000141448
ZIC2 22 / 483 zf-C2H2 ENSG00000043355
CEBPG 14 / 483 TF_bZIP ENSG00000153879
MNT 12 / 483 bHLH ENSG00000070444

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
CDX2 44 73 117
ZNF217 43 46 89
FOXP1 42 75 117
JUNB 41 63 104
ZNF219 35 64 99
HNF1A 44 75 119
VDR 37 75 112
RFX2 43 69 112
BHLHE40 43 63 106
ELF1 36 75 111
ELF3 46 74 120
ZBTB7A 44 47 91
CEBPA 44 52 96
CEBPG 37 35 72
MECOM 44 61 105
NFE2L2 45 70 115
ETS2 46 49 95
NR4A2 39 72 111
KLF5 46 75 121
KLF4 39 74 113
KLF3 45 64 109
FOSL2 45 64 109
MYC 45 68 113
RREB1 46 74 120
NR4A1 37 67 104
FOS 42 66 108
MNT 42 43 85
FOXD2 43 71 114
JUND 38 72 110
EHF 44 75 119
SP3 31 75 106
GATA6 44 57 101
ZIC2 25 73 98
IRF2 40 75 115
MYB 42 73 115
MAX 40 70 110
TCF7L2 42 73 115
MEF2A 43 74 117
SREBF1 42 69 111
ATF3 42 59 101
HES1 42 59 101
TGIF1 42 71 113

Expression of TFs in all CRCs