TF information

TF name: ELF3
TF family: ETS
Ensembl gene ID: ENSG00000163435
Ensembl protein ID: ENSP00000356253, ENSP00000356252, ENSP00000352673
Entrez gene ID: 1999
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of ELF3 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_01_046Cell lineMammary GlandMCF-70.8
Sample_01_059Cell lineLungPC-90.66666666666667
Sample_02_021Cell lineColonV4290.31392332084174
Sample_02_029Cell lineColorectalLS174T0.66666666666667
Sample_02_080Cell lineLungCalu-31
Sample_02_095Cell lineMammary GlandMDA-MB-4681
Sample_02_096Cell lineMammary GlandZR-75-1_10.90217391304348
Sample_02_164Cell lineLungH2087_Parental0.8
Sample_02_166Cell lineMammary GlandHCC1954_Parental0.848
Sample_02_168Cell lineProstateLNCaP0.93536121673004
Sample_02_189Cell lineStomachSNU0161
Sample_02_192Cell lineStomachMKN450.66666666666667
Sample_02_195Cell lineStomachOCUM11
Sample_02_196Cell lineStomachNCC590.78571428571429
Sample_02_198Cell lineStomachSNU161
Sample_02_199Cell lineStomachKATO31
Sample_02_200Cell lineStomachRERF-GC-1B1
Sample_02_203Cell lineStomachYCC211
Sample_02_204Cell lineStomachIM950.90909090909091
Sample_02_205TissueStomachGastric_Primary_Sample_T0.88148148148148
Sample_02_208Cell lineStomachYCC30.875
Sample_02_227Cell lineOesophagusTE70.8
Sample_02_228Cell lineOesophagusKYSE5100.51258154706431
Sample_02_236Cell lineColonV2060.86749482401656
Sample_02_237Cell lineColonV3890.99992637585128
Sample_02_241Cell lineColonV4561
Sample_02_242Cell lineColonV4810.97827340895982
Sample_02_268Cell lineKidneyA-4980.18183496400222
Sample_02_322Cell lineColonCaco-20.98250336473755
Sample_02_354Cell lineColonColo2051
Sample_02_355Cell lineColonHCT151
Sample_02_358Cell lineColonLS1800.27093206951027
Sample_02_404Cell lineMammary GlandZR-75-1_21
Sample_02_424Cell lineColonSW6201

ELF3 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_01_046Mammary GlandCell lineMCF-7
Sample_01_059LungCell linePC-9
Sample_02_029ColorectalCell lineLS174T
Sample_02_080LungCell lineCalu-3
Sample_02_095Mammary GlandCell lineMDA-MB-468
Sample_02_096Mammary GlandCell lineZR-75-1_1
Sample_02_164LungCell lineH2087_Parental
Sample_02_166Mammary GlandCell lineHCC1954_Parental
Sample_02_168ProstateCell lineLNCaP
Sample_02_189StomachCell lineSNU016
Sample_02_192StomachCell lineMKN45
Sample_02_195StomachCell lineOCUM1
Sample_02_196StomachCell lineNCC59
Sample_02_198StomachCell lineSNU16
Sample_02_199StomachCell lineKATO3
Sample_02_200StomachCell lineRERF-GC-1B
Sample_02_203StomachCell lineYCC21
Sample_02_204StomachCell lineIM95
Sample_02_205StomachTissueGastric_Primary_Sample_T
Sample_02_208StomachCell lineYCC3
Sample_02_227OesophagusCell lineTE7
Sample_02_236ColonCell lineV206
Sample_02_237ColonCell lineV389
Sample_02_241ColonCell lineV456
Sample_02_242ColonCell lineV481
Sample_02_322ColonCell lineCaco-2
Sample_02_354ColonCell lineColo205
Sample_02_355ColonCell lineHCT15
Sample_02_404Mammary GlandCell lineZR-75-1_2
Sample_02_424ColonCell lineSW620

ELF3 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with ELF3
Download

Mutation of ELF3
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of ELF3

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr1201984339201984339AGexonicELF3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201980322201980334AGCTCGGAGGACT-exonicELF3frameshift CHOL|1|35|0.02857
-chr1201984341201984341-AexonicELF3stopgain BLCA|1|396|0.00253
-chr1201980398201980398-CexonicELF3frameshift BLCA|1|396|0.00253
-chr1201982386201982389AGAG-exonicELF3frameshift BLCA|2|396|0.00505
-chr1201981870201981870-TexonicELF3frameshift BLCA|1|396|0.00253
-chr1201980326201980326CAexonicELF3stopgain BLCA|1|396|0.00253
-chr1201983018201983018-GexonicELF3frameshift COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr1201984378201984378GCexonicELF3nonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr1201983058201983058TAexonicELF3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201984377201984377CTexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201981105201981105GTexonicELF3stopgain CESC|1|194|0.00515
-chr1201980364201980364ACexonicELF3nonsynonymous BRCA|1|982|0.00102
-chr1201981520201981520-GexonicELF3frameshift BLCA|1|396|0.00253
-chr1201981084201981084-AsplicingELF3unknown BLCA|1|396|0.00253
-chr1201982398201982407CTGTCTCGAG-exonicELF3frameshift -
-chr1201982911201982911GAintronicELF3unknown CESC|1|194|0.00515
-chr1201983027201983027-AexonicELF3frameshift BLCA|1|396|0.00253
-chr1201981500201981500GCexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201981484201981484CTexonicELF3nonsynonymous BLCA|1|396|0.00253,THCA|1|504|0.00198
-chr1201981500201981500GTexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201983137201983137TCexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201983142201983142CTexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201982393201982393-GexonicELF3frameshift BLCA|1|396|0.00253
-chr1201981535201981535-CexonicELF3frameshift BLCA|1|396|0.00253,STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201982405201982405GCexonicELF3nonsynonymous BLCA|4|396|0.01010
-chr1201984422201984422GAexonicELF3nonsynonymous CESC|1|194|0.00515
-chr1201981484201981484C-exonicELF3frameshift BLCA|2|396|0.00505
-chr1201980376201980376GCexonicELF3nonsynonymous LUAD|1|543|0.00184
-chr1201982128201982128-AexonicELF3frameshift BLCA|1|396|0.00253
-chr1201981485201981494TGATGAGCTC-exonicELF3frameshift BLCA|1|396|0.00253
-chr1201982359201982359ATexonicELF3nonsynonymous UCEC|1|248|0.00403
-chr1201984374201984374GAexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201984393201984393ACexonicELF3nonsynonymous CHOL|1|35|0.02857
-chr1201982373201982373GCexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201984390201984390AGexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201980419201980419-GexonicELF3frameshift KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr1201982111201982111-GGTGexonicELF3frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201984418201984418GAexonicELF3stopgain CESC|1|194|0.00515
-chr1201981503201981503CTexonicELF3synonymous SKCM|1|368|0.00272
-chr1201983066201983066CTexonicELF3synonymous SKCM|2|368|0.00543
-chr1201984394201984394GCexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201981273201981273GTexonicELF3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201982329201982329GCexonicELF3nonsynonymous BLCA|2|396|0.00505
-chr1201982158201982158CGexonicELF3nonsynonymous LUAD|1|543|0.00184
-chr1201984358201984358C-exonicELF3frameshift COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1201982144201982144AGexonicELF3nonsynonymous PAAD|1|185|0.00541
-chr1201984496201984496CTUTR3ELF3unknown BRCA|1|982|0.00102
-chr1201980419201980419AGexonicELF3nonsynonymous LUAD|1|543|0.00184
-chr1201983066201983066C-exonicELF3frameshift COAD|1|367|0.00272,COADREAD|2|489|0.00409,READ|1|122|0.00820
-chr1201980286201980286AGexonicELF3nonsynonymous BRCA|1|982|0.00102
-chr1201981807201981807GAexonicELF3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1201981243201981243GAexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201982370201982370CGexonicELF3nonsynonymous LIHC|1|373|0.00268
-chr1201981088201981088AGexonicELF3nonsynonymous HNSC|1|512|0.00195
-chr1201984366201984376GGGTGGATGGC-exonicELF3frameshift OV|1|469|0.00213
-chr1201981790201981790GAexonicELF3synonymous SKCM|1|368|0.00272
rs556702229chr1201981177201981177GAexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201983137201983137TGexonicELF3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs148651345chr1201982112201982112CTexonicELF3synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201982413201982413GCexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201981255201981255CTexonicELF3synonymous CESC|1|194|0.00515
-chr1201984342201984342ATexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201982071201982071CTintronicELF3unknown STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201980290201980290AGexonicELF3nonsynonymous UCEC|1|248|0.00403
-chr1201982373201982373GAexonicELF3nonsynonymous CESC|1|194|0.00515
-chr1201982339201982339C-exonicELF3frameshift BLCA|1|396|0.00253
-chr1201981549201981549GAexonicELF3nonsynonymous CESC|1|194|0.00515
-chr1201981192201981192GAexonicELF3nonsynonymous BLCA|1|396|0.00253,LUAD|1|543|0.00184
-chr1201981119201981119CGexonicELF3nonsynonymous CESC|1|194|0.00515
-chr1201981494201981501CAGTTGGA-exonicELF3frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201980282201980282G-exonicELF3frameshift BLCA|1|396|0.00253
-chr1201981877201981877CTexonicELF3synonymous SKCM|1|368|0.00272
-chr1201984387201984387TCexonicELF3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201981142201981142ATexonicELF3nonsynonymous LUAD|1|543|0.00184
-chr1201981253201981253GAexonicELF3nonsynonymous SARC|1|247|0.00405
-chr1201984579201984579GAUTR3ELF3unknown UCEC|1|248|0.00403
rs769104884chr1201982319201982319GAexonicELF3nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr1201983060201983060CAexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201984385201984385CGexonicELF3synonymous BRCA|1|982|0.00102
-chr1201982416201982416GCexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201980309201980309C-exonicELF3frameshift BLCA|2|396|0.00505
-chr1201981267201981267-TexonicELF3frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201984155201984155GTintronicELF3unknown CESC|1|194|0.00515
-chr1201983146201983146CTexonicELF3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs750329636chr1201981202201981202GAexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201983060201983060C-exonicELF3frameshift LUAD|1|543|0.00184
-chr1201982405201982405GTexonicELF3stopgain COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr1201984414201984414GTexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201981201201981201CGexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201981121201981121GAexonicELF3stopgain ESCA|1|185|0.00541
-chr1201981084201981084GAsplicingELF3splicing BLCA|1|396|0.00253
-chr1201984401201984401AGexonicELF3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201981984201981984GTintronicELF3unknown ESCA|1|185|0.00541
rs779747541chr1201982405201982405GAexonicELF3nonsynonymous PCPG|1|184|0.00543
-chr1201980309201980309CTexonicELF3synonymous SKCM|1|368|0.00272
-chr1201981271201981271-GexonicELF3frameshift BLCA|1|396|0.00253
-chr1201983015201983015-ACGexonicELF3nonframeshift COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr1201981872201981872GAexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201984068201984068CTintronicELF3unknown CESC|1|194|0.00515
-chr1201983144201983144GAexonicELF3synonymous LUSC|1|178|0.00562
rs55729978chr1201981774201981774GAexonicELF3nonsynonymous DLBC|2|48|0.04167
-chr1201981564201981564GTexonicELF3nonsynonymous HNSC|1|512|0.00195
rs745722163chr1201981124201981124CTexonicELF3nonsynonymous CESC|1|194|0.00515
-chr1201981118201981118-CexonicELF3frameshift COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1201984408201984408CTexonicELF3nonsynonymous BLCA|1|396|0.00253
rs755079997chr1201982361201982361GAexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201982390201982390-AexonicELF3stopgain STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201983043201983043CGexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201981365201981365CTintronicELF3unknown CESC|1|194|0.00515
-chr1201982377201982377GTexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201984366201984366GTexonicELF3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201980293201980293T-exonicELF3frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201981564201981565GG-exonicELF3frameshift BLCA|2|396|0.00505
-chr1201982372201982372CTexonicELF3stopgain SKCM|1|368|0.00272
rs202089261chr1201983060201983060CTexonicELF3synonymous CESC|1|194|0.00515
-chr1201982311201982311-AexonicELF3frameshift BLCA|1|396|0.00253
-chr1201980352201980352C-exonicELF3frameshift COAD|2|367|0.00545,COADREAD|2|489|0.00409
-chr1201981809201981809CTexonicELF3stopgain BLCA|1|396|0.00253
-chr1201984388201984388-TexonicELF3frameshift LUAD|1|543|0.00184
-chr1201983138201983153GAGCCGGGCCATGAGG-exonicELF3nonframeshift BLCA|1|396|0.00253
-chr1201980363201980363CTexonicELF3synonymous LUSC|1|178|0.00562
-chr1201984345201984345AGexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201980352201980352CTexonicELF3nonsynonymous SKCM|1|368|0.00272
-chr1201981145201981145GAexonicELF3stopgain PAAD|1|185|0.00541
-chr1201981489201981489GAexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201982385201982385A-exonicELF3frameshift LIHC|1|373|0.00268
-chr1201981158201981164AGTGGAG-exonicELF3frameshift LUAD|1|543|0.00184
-chr1201983122201983122TCexonicELF3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr1201983049201983049GCexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201984395201984395TCexonicELF3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr1201982416201982416-AexonicELF3frameshift BLCA|1|396|0.00253
-chr1201982087201982087CGexonicELF3nonsynonymous BLCA|2|396|0.00505
-chr1201981202201981202GCexonicELF3nonsynonymous BLCA|1|396|0.00253
-chr1201981146201981146GAexonicELF3stopgain BLCA|1|396|0.00253
-chr1201981100201981100-GexonicELF3frameshift LIHC|1|373|0.00268

Disease information of ELF3
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
ELF3 Biliary Tract Neoplasm C04;C06 Neoplastic Process CTD_human
ELF3 Lung Injury C08;C26 Injury or Poisoning CTD_human
ELF3 Biliary Tract Cancer C04;C06 Neoplastic Process CTD_human
ELF3 Chronic Lung Injury C08;C26 Disease or Syndrome CTD_human

Pathway associated with ELF3
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0001604 PDGF signaling pathway panther 113 1684

Go term information of ELF3
GO_term_name GO_term_type TF_name
GO_MAMMARY_GLAND_MORPHOGENESIS BP ELF3
GO_GLAND_MORPHOGENESIS BP ELF3
GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION BP ELF3
GO_POSITIVE_REGULATION_OF_RNA_SPLICING BP ELF3
GO_POSITIVE_REGULATION_OF_MRNA_PROCESSING BP ELF3
GO_POSITIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS BP ELF3
GO_SPERM_MOTILITY BP ELF3
GO_POSITIVE_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME BP ELF3
GO_SEXUAL_REPRODUCTION BP ELF3
GO_REGULATION_OF_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME BP ELF3
GO_EPIDERMIS_DEVELOPMENT BP ELF3
GO_MRNA_BINDING MF ELF3

Survival analysis of ELF3



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of ELF3