Sample overview of HCC1954_Parental

Sample ID: Sample_02_166
Biosample type: Cell line
Tissue type: Mammary Gland
Biosample name: HCC1954_Parental
Data source: NCBI GEO/SRA
GSE ID: GSE72956
Cancer type: breast adenocarcinoma
CRC number: 250
TF number of all CRCs: 37
TF list of all CRCs: SMAD3, MYC, RUNX1, IRF1, ELF3, STAT3, MAFK, RARA, EHF, RXRA, TFAP2A, FOXA1, TGIF1, TFAP2C, HES1, BHLHE40, KLF4, NR2F2, JUNB, SREBF1, CREB3L2, GATA3, SOX9, FOSL2, SOX4, IRX2, GLIS3, TP63, SP3, HIF1A, ZNF217, ZBTB7B, MEF2D, ETS2, HOXB2, CEBPD, NFIB

The most representative CRC of HCC1954_Parental
Download
Relationship plot of CRC model
TF number of this CRC: 13
CRC socre: 169.3846
TF list of the most representative CRC
TF name TF family Frequency of TFs
CEBPD TF_bZIP 24 / 250
EHF ETS 185 / 250
ELF3 ETS 212 / 250
KLF4 zf-C2H2 111 / 250
MYC bHLH 250 / 250
RARA THR-like 192 / 250
RUNX1 Runt 250 / 250
RXRA RXR-like 182 / 250
SMAD3 MH1 250 / 250
STAT3 STAT 212 / 250
TFAP2A AP-2 150 / 250
TGIF1 Homeobox 134 / 250
ZNF217 zf-C2H2 50 / 250

All CRCs of HCC1954_Parental
Download
CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
Download

TF name Frequency of TFs TF family Ensembl ID
RUNX1 250 / 250 Runt ENSG00000159216
SMAD3 250 / 250 MH1 ENSG00000166949
MYC 250 / 250 bHLH ENSG00000136997
IRF1 226 / 250 IRF ENSG00000125347
STAT3 212 / 250 STAT ENSG00000168610
ELF3 212 / 250 ETS ENSG00000163435
MAFK 194 / 250 TF_bZIP ENSG00000198517
RARA 192 / 250 THR-like ENSG00000131759
EHF 185 / 250 ETS ENSG00000135373
RXRA 182 / 250 RXR-like ENSG00000186350
TFAP2A 150 / 250 AP-2 ENSG00000137203
FOXA1 150 / 250 Fork_head ENSG00000129514
TFAP2C 134 / 250 AP-2 ENSG00000087510
TGIF1 134 / 250 Homeobox ENSG00000177426
HES1 126 / 250 bHLH ENSG00000114315
BHLHE40 119 / 250 bHLH ENSG00000134107
KLF4 111 / 250 zf-C2H2 ENSG00000136826
NR2F2 107 / 250 RXR-like ENSG00000185551
JUNB 106 / 250 TF_bZIP ENSG00000171223
SREBF1 97 / 250 bHLH ENSG00000072310
CREB3L2 89 / 250 TF_bZIP ENSG00000182158
GATA3 89 / 250 zf-GATA ENSG00000107485
SOX9 85 / 250 HMG ENSG00000125398
SOX4 78 / 250 HMG ENSG00000124766
FOSL2 78 / 250 TF_bZIP ENSG00000075426
IRX2 68 / 250 Homeobox ENSG00000170561
GLIS3 65 / 250 zf-C2H2 ENSG00000107249
SP3 64 / 250 zf-C2H2 ENSG00000172845
TP63 64 / 250 P53 ENSG00000073282
HIF1A 58 / 250 Others ENSG00000100644
ZNF217 50 / 250 zf-C2H2 ENSG00000171940
ZBTB7B 48 / 250 ZBTB ENSG00000160685
MEF2D 46 / 250 SRF ENSG00000116604
ETS2 40 / 250 ETS ENSG00000157557
HOXB2 38 / 250 Homeobox ENSG00000173917
CEBPD 24 / 250 TF_bZIP ENSG00000221869
NFIB 14 / 250 CTF/NFI ENSG00000147862

Indegree and outdegree of TFs
Download

TF name Indegree Outdegree Node connections
ZNF217 38 37 75
GLIS3 30 56 86
JUNB 35 53 88
HIF1A 38 38 76
SMAD3 38 58 96
SOX9 35 57 92
BHLHE40 36 55 91
ELF3 37 58 95
SOX4 33 56 89
RARA 37 57 94
FOXA1 36 57 93
RUNX1 38 57 95
STAT3 37 57 94
CEBPD 37 31 68
TFAP2A 35 58 93
TFAP2C 35 58 93
NR2F2 36 54 90
ETS2 38 40 78
KLF4 35 58 93
FOSL2 35 54 89
TP63 36 49 85
MYC 38 53 91
IRX2 33 47 80
ZBTB7B 32 52 84
HOXB2 35 37 72
SP3 33 58 91
RXRA 37 56 93
EHF 37 58 95
GATA3 35 56 91
NFIB 32 47 79
IRF1 37 57 94
MAFK 36 57 93
CREB3L2 38 46 84
SREBF1 36 56 92
MEF2D 33 52 85
HES1 36 55 91
TGIF1 37 56 93

Expression of TFs in all CRCs