Cancer CRCdb

TF information

TF name:	TP63
TF family:	P53
Ensembl gene ID:	ENSG00000073282
Ensembl protein ID:	ENSP00000389485, ENSP00000387839, ENSP00000392488, ENSP00000407144, ENSP00000394337, ENSP00000376254, ENSP00000346614, ENSP00000376253, ENSP00000264731, ENSP00000317510, ENSP00000376256, ENSP00000401661
Entrez gene ID:	8626

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of TP63 in all biosamples

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Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_166	Cell line	Mammary Gland	HCC1954_Parental	0.256
Sample_02_227	Cell line	Oesophagus	TE7	0.4
Sample_02_228	Cell line	Oesophagus	KYSE510	0.97483690587139
Sample_02_394	Cell line	Mammary Gland	T-47D_2	0.76923076923077
Sample_02_403	Cell line	Mammary Gland	T-47D_untreat	0.39772727272727

TP63 distribution in samples’ most representative CRC

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Sample ID	Tissue type	Biosample type	Biosample name
Sample_02_228	Oesophagus	Cell line	KYSE510
Sample_02_394	Mammary Gland	Cell line	T-47D_2
Sample_02_403	Mammary Gland	Cell line	T-47D_untreat

TP63 distribution in all CRCs

Genomic distribution of SEs associated with TP63

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Mutation of TP63

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Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of TP63

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr3	189604318	189604318	T	G	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189612152	189612152	G	T	exonic	TP63	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	189612133	189612133	G	T	exonic	TP63	nonsynonymous	LUAD\|2\|543\|0.00368
-	chr3	189526137	189526137	A	G	exonic	TP63	nonsynonymous	HNSC\|1\|512\|0.00195
rs779741406	chr3	189585657	189585657	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189607256	189607256	A	G	exonic	TP63	synonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr3	189607201	189607201	C	T	exonic	TP63	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	189585695	189585695	G	T	exonic	TP63	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	189604275	189604275	T	C	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
rs752535926	chr3	189582203	189582203	C	T	exonic	TP63	synonymous	BRCA\|1\|982\|0.00102
-	chr3	189586470	189586470	C	A	exonic	TP63	stopgain	TGCT\|1\|155\|0.00645
-	chr3	189586504	189586504	C	T	exonic	TP63	synonymous	UCEC\|1\|248\|0.00403
-	chr3	189608638	189608638	C	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189607219	189607219	C	T	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189612207	189612207	A	C	exonic	TP63	synonymous	BRCA\|1\|982\|0.00102
rs773237715	chr3	189612035	189612035	C	T	exonic	TP63	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	189586432	189586432	G	A	exonic	TP63	synonymous	HNSC\|1\|512\|0.00195
-	chr3	189611994	189611994	G	A	splicing	TP63	splicing	SKCM\|1\|368\|0.00272
rs766239462	chr3	189526150	189526150	C	T	exonic	TP63	synonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
-	chr3	189590653	189590653	G	A	exonic	TP63	synonymous	SKCM\|2\|368\|0.00543
rs151335217	chr3	189526123	189526123	G	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189612184	189612184	C	G	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189526252	189526252	A	G	exonic	TP63	synonymous	LUAD\|1\|543\|0.00184
rs777306829	chr3	189604292	189604292	C	T	exonic	TP63	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr3	189604229	189604229	C	T	exonic	TP63	synonymous	BLCA\|1\|396\|0.00253
-	chr3	189526228	189526228	-	A	exonic	TP63	frameshift	HNSC\|1\|512\|0.00195
-	chr3	189582051	189582051	C	A	exonic	TP63	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	189585726	189585726	C	A	exonic	TP63	synonymous	CESC\|1\|194\|0.00515
-	chr3	189456442	189456442	C	T	exonic	TP63	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
rs201188464	chr3	189526257	189526257	C	T	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189587135	189587135	T	C	exonic	TP63	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr3	189608665	189608665	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189611999	189611999	T	G	exonic	TP63	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	189586439	189586439	G	A	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189587175	189587175	G	A	exonic	TP63	nonsynonymous	SARC\|1\|247\|0.00405,SKCM\|1\|368\|0.00272
rs375508394	chr3	189526115	189526115	G	A	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189608589	189608589	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
rs376910274	chr3	189586506	189586506	G	A	splicing	TP63	splicing	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs376627647	chr3	189349323	189349323	C	T	exonic	TP63	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr3	189608582	189608582	T	A	exonic	TP63	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	189584546	189584546	C	G	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189604307	189604307	C	G	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189604224	189604224	C	T	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189584510	189584510	G	A	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,SKCM\|1\|368\|0.00272
-	chr3	189612176	189612176	G	A	exonic	TP63	nonsynonymous	OV\|1\|469\|0.00213,SKCM\|3\|368\|0.00815
rs142762485	chr3	189612073	189612073	G	A	exonic	TP63	nonsynonymous	SKCM\|4\|368\|0.01087
rs148577576	chr3	189612036	189612036	G	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272,UCEC\|1\|248\|0.00403
-	chr3	189584500	189584500	C	T	exonic	TP63	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189597936	189597936	C	G	exonic	TP63	nonsynonymous	TGCT\|1\|155\|0.00645
-	chr3	189455623	189455623	G	C	exonic	TP63	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	189507602	189507602	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189582183	189582183	G	A	exonic	TP63	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	189587173	189587173	A	G	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189587156	189587156	G	T	exonic	TP63	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	189612120	189612120	T	C	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189587113	189587113	C	-	exonic	TP63	frameshift	LUAD\|1\|543\|0.00184
-	chr3	189582097	189582097	C	T	exonic	TP63	nonsynonymous	CESC\|1\|194\|0.00515
-	chr3	189585728	189585728	G	A	exonic	TP63	nonsynonymous	ESCA\|1\|185\|0.00541
rs759567158	chr3	189526204	189526204	C	T	exonic	TP63	synonymous	LUSC\|1\|178\|0.00562
-	chr3	189604281	189604281	A	G	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189456537	189456537	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189526280	189526280	C	T	exonic	TP63	stopgain	SKCM\|1\|368\|0.00272
-	chr3	189526287	189526287	C	T	exonic	TP63	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	189586427	189586427	G	T	exonic	TP63	nonsynonymous	TGCT\|1\|155\|0.00645
-	chr3	189585724	189585724	A	G	exonic	TP63	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr3	189608623	189608623	G	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
rs751300168	chr3	189526152	189526152	C	T	exonic	TP63	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr3	189456461	189456461	G	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189612211	189612211	C	A	exonic	TP63	synonymous	LUAD\|1\|543\|0.00184
-	chr3	189604240	189604240	G	A	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189455639	189455639	T	C	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189582120	189582120	G	A	exonic	TP63	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122,PAAD\|1\|185\|0.00541,PCPG\|1\|184\|0.00543
rs762371837	chr3	189526184	189526184	G	A	exonic	TP63	nonsynonymous	UCEC\|1\|248\|0.00403
rs767553568	chr3	189582089	189582089	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
rs777255243	chr3	189597951	189597951	G	A	exonic	TP63	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr3	189586405	189586405	G	C	exonic	TP63	synonymous	BLCA\|1\|396\|0.00253
-	chr3	189349318	189349318	C	T	exonic	TP63	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	189349311	189349311	T	C	exonic	TP63	nonsynonymous	HNSC\|1\|512\|0.00195
rs34713855	chr3	189612269	189612269	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189586404	189586404	G	T	exonic	TP63	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr3	189612149	189612149	G	-	exonic	TP63	frameshift	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs141847552	chr3	189607208	189607208	C	T	exonic	TP63	synonymous	HNSC\|1\|512\|0.00195
-	chr3	189455608	189455608	G	T	exonic	TP63	stopgain	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr3	189526084	189526084	C	T	exonic	TP63	synonymous	SKCM\|2\|368\|0.00543
-	chr3	189586379	189586379	C	T	exonic	TP63	synonymous	SKCM\|2\|368\|0.00543
-	chr3	189349361	189349361	C	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
rs866938979	chr3	189526302	189526302	C	T	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253,BRCA\|1\|982\|0.00102,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	189349368	189349368	T	C	splicing	TP63	splicing	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs748609799	chr3	189586471	189586471	G	A	exonic	TP63	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189,PRAD\|1\|499\|0.00200
rs147389337	chr3	189607196	189607196	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189456507	189456507	G	C	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189582116	189582116	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189584556	189584556	G	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189584511	189584511	G	A	exonic	TP63	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189607225	189607225	C	T	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189585687	189585687	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
rs145730343	chr3	189526135	189526135	C	T	exonic	TP63	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs765564666	chr3	189526226	189526226	G	A	exonic	TP63	nonsynonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
-	chr3	189456514	189456514	G	T	exonic	TP63	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	189607202	189607202	C	G	exonic	TP63	synonymous	UCEC\|1\|248\|0.00403
-	chr3	189349364	189349364	G	T	exonic	TP63	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr3	189586483	189586483	G	C	exonic	TP63	nonsynonymous	CESC\|1\|194\|0.00515,KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr3	189526134	189526134	C	T	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189584586	189584586	G	A	exonic	TP63	synonymous	LIHC\|1\|373\|0.00268
-	chr3	189604291	189604291	G	A	exonic	TP63	synonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
rs755677647	chr3	189456541	189456541	C	T	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189526213	189526213	C	A	exonic	TP63	synonymous	HNSC\|1\|512\|0.00195
-	chr3	189526085	189526085	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189608623	189608623	G	C	exonic	TP63	synonymous	BLCA\|1\|396\|0.00253
-	chr3	189586389	189586389	G	A	exonic	TP63	nonsynonymous	UCEC\|1\|248\|0.00403
rs193921145	chr3	189582118	189582118	G	A	exonic	TP63	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
rs113993967	chr3	189586386	189586386	G	A	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
rs866267914	chr3	189586422	189586422	G	A	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253,SKCM\|1\|368\|0.00272
-	chr3	189455613	189455613	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189526145	189526145	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189608638	189608638	C	T	exonic	TP63	synonymous	BRCA\|1\|982\|0.00102
-	chr3	189590692	189590692	G	A	exonic	TP63	synonymous	LUAD\|1\|543\|0.00184
-	chr3	189611996	189611996	A	T	exonic	TP63	nonsynonymous	UCEC\|1\|248\|0.00403
rs121908849	chr3	189584501	189584501	G	A	exonic	TP63	nonsynonymous	HNSC\|1\|512\|0.00195,SKCM\|1\|368\|0.00272,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	189585724	189585724	A	C	exonic	TP63	nonsynonymous	OV\|1\|469\|0.00213
-	chr3	189608650	189608650	G	C	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189585680	189585680	G	C	exonic	TP63	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr3	189526100	189526100	C	T	exonic	TP63	stopgain	SKCM\|1\|368\|0.00272
-	chr3	189526244	189526244	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
rs753959658	chr3	189604231	189604231	G	A	exonic	TP63	synonymous	BRCA\|1\|982\|0.00102
-	chr3	189526315	189526315	G	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272,STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr3	189582062	189582062	G	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
rs757222487	chr3	189456558	189456558	A	G	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs143591434	chr3	189586503	189586503	G	A	exonic	TP63	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	189455608	189455608	G	A	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189349350	189349350	G	A	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
rs761885185	chr3	189587118	189587118	C	T	exonic	TP63	nonsynonymous	SKCM\|8\|368\|0.02174
-	chr3	189597954	189597954	C	T	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189582134	189582134	-	A	exonic	TP63	frameshift	HNSC\|1\|512\|0.00195
-	chr3	189612219	189612219	G	T	exonic	TP63	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	189526170	189526170	C	T	exonic	TP63	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr3	189587146	189587146	C	T	exonic	TP63	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr3	189597958	189597958	G	A	exonic	TP63	synonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
rs121908841	chr3	189586404	189586404	G	A	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189526305	189526305	C	T	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs140374868	chr3	189587144	189587144	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189612204	189612204	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189526215	189526215	C	G	exonic	TP63	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	189612157	189612157	C	T	exonic	TP63	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	189612241	189612241	A	G	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189526189	189526189	G	A	exonic	TP63	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,UCEC\|1\|248\|0.00403
-	chr3	189526287	189526287	C	G	exonic	TP63	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr3	189526205	189526205	G	T	exonic	TP63	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	189586422	189586422	G	C	exonic	TP63	nonsynonymous	CESC\|1\|194\|0.00515
-	chr3	189582022	189582022	A	C	exonic	TP63	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr3	189612137	189612137	C	T	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189604307	189604307	C	T	exonic	TP63	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
rs772653802	chr3	189526183	189526183	C	T	exonic	TP63	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189612175	189612175	C	T	exonic	TP63	stopgain	PRAD\|1\|499\|0.00200
-	chr3	189590662	189590662	G	C	exonic	TP63	nonsynonymous	LUSC\|1\|178\|0.00562
rs761624304	chr3	189612233	189612233	A	G	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189526151	189526151	G	A	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|3\|395\|0.00759,STES\|3\|395\|0.00759
-	chr3	189582020	189582020	G	T	splicing	TP63	splicing	HNSC\|2\|512\|0.00391
-	chr3	189584508	189584508	G	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189587161	189587161	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
rs775719080	chr3	189584487	189584487	T	C	exonic	TP63	synonymous	ESCA\|1\|185\|0.00541
-	chr3	189608648	189608648	C	G	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189587169	189587169	C	A	exonic	TP63	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	189455563	189455563	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189456560	189456560	G	A	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs148937466	chr3	189586459	189586459	G	A	exonic	TP63	synonymous	UCEC\|1\|248\|0.00403
-	chr3	189586378	189586378	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
rs28673064	chr3	189349247	189349247	A	T	UTR5	TP63	unknown	KIPAN\|2\|799\|0.00250,KIRC\|2\|451\|0.00443,LUAD\|1\|543\|0.00184,PRAD\|1\|499\|0.00200
rs754089583	chr3	189586498	189586498	G	A	exonic	TP63	synonymous	SKCM\|2\|368\|0.00543
-	chr3	189455616	189455616	C	T	exonic	TP63	synonymous	SKCM\|2\|368\|0.00543
-	chr3	189587160	189587160	C	T	exonic	TP63	stopgain	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr3	189585720	189585720	G	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
rs267599728	chr3	189526072	189526072	G	A	exonic	TP63	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,SKCM\|2\|368\|0.00543
-	chr3	189612142	189612142	G	T	exonic	TP63	stopgain	CESC\|1\|194\|0.00515
-	chr3	189586431	189586431	G	T	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189582206	189582206	G	T	exonic	TP63	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	189585722	189585722	A	G	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189608585	189608585	G	T	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	189587178	189587178	G	T	exonic	TP63	stopgain	ESCA\|1\|185\|0.00541
rs772867228	chr3	189455644	189455644	G	A	exonic	TP63	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr3	189590656	189590656	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
rs576449010	chr3	189586505	189586505	C	T	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs147148566	chr3	189586470	189586470	C	T	exonic	TP63	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222,SKCM\|2\|368\|0.00543
-	chr3	189608582	189608582	T	C	exonic	TP63	synonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr3	189612277	189612277	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189584533	189584533	G	T	exonic	TP63	stopgain	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
rs761707773	chr3	189349364	189349364	G	A	exonic	TP63	synonymous	KIPAN\|2\|799\|0.00250,KIRC\|2\|451\|0.00443
-	chr3	189526227	189526227	C	T	exonic	TP63	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr3	189604248	189604248	T	C	exonic	TP63	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs377757904	chr3	189582154	189582154	C	T	exonic	TP63	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	189586385	189586385	C	T	exonic	TP63	stopgain	SKCM\|2\|368\|0.00543
-	chr3	189455579	189455579	C	T	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189586386	189586386	G	T	exonic	TP63	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	189526314	189526314	C	T	exonic	TP63	nonsynonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr3	189590688	189590688	A	G	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189526126	189526126	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189584482	189584482	C	T	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189608648	189608648	C	T	exonic	TP63	stopgain	CESC\|1\|194\|0.00515
rs779128548	chr3	189526160	189526160	A	T	exonic	TP63	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	189612137	189612137	C	G	exonic	TP63	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr3	189585726	189585726	C	T	exonic	TP63	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs865905084	chr3	189608669	189608669	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189526267	189526267	C	T	exonic	TP63	synonymous	BLCA\|1\|396\|0.00253,COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,SKCM\|1\|368\|0.00272
-	chr3	189604206	189604206	C	T	exonic	TP63	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr3	189421254	189421254	-	GATCGATAGACA	intronic	TP63	unknown	-
-	chr3	189526081	189526081	G	T	exonic	TP63	synonymous	HNSC\|1\|512\|0.00195
-	chr3	189612028	189612028	C	T	exonic	TP63	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,SKCM\|2\|368\|0.00543,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|2\|248\|0.00806
-	chr3	189455532	189455532	C	A	exonic	TP63	nonsynonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
-	chr3	189612226	189612226	G	A	exonic	TP63	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	189582106	189582106	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189526191	189526191	C	A	exonic	TP63	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	189526276	189526276	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189612186	189612186	C	G	exonic	TP63	synonymous	BLCA\|1\|396\|0.00253
-	chr3	189611995	189611995	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
rs375593834	chr3	189586486	189586486	C	T	exonic	TP63	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs758433941	chr3	189526243	189526243	C	T	exonic	TP63	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs369453583	chr3	189604233	189604233	A	G	exonic	TP63	nonsynonymous	SARC\|1\|247\|0.00405
-	chr3	189526296	189526303	CCAAGTCG	-	exonic	TP63	frameshift	BLCA\|1\|396\|0.00253
-	chr3	189582172	189582172	G	A	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189582020	189582020	G	A	splicing	TP63	splicing	HNSC\|1\|512\|0.00195
-	chr3	189585721	189585721	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189597916	189597916	T	C	exonic	TP63	synonymous	HNSC\|1\|512\|0.00195
rs752435519	chr3	189597919	189597919	C	T	exonic	TP63	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	189584544	189584544	C	T	exonic	TP63	synonymous	BLCA\|2\|396\|0.00505
-	chr3	189597878	189597878	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189349330	189349330	C	T	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253
rs138832017	chr3	189604298	189604298	G	A	exonic	TP63	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	189586371	189586371	G	T	exonic	TP63	nonsynonymous	ESCA\|1\|185\|0.00541
rs545050848	chr3	189584565	189584565	G	A	exonic	TP63	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	189456456	189456456	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189612096	189612096	C	T	exonic	TP63	synonymous	SKCM\|4\|368\|0.01087
-	chr3	189587149	189587149	C	T	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189612186	189612186	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189349307	189349307	G	A	exonic	TP63	nonsynonymous	BLCA\|1\|396\|0.00253,SKCM\|1\|368\|0.00272
-	chr3	189349340	189349340	G	A	exonic	TP63	synonymous	PAAD\|1\|185\|0.00541
-	chr3	189608668	189608668	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
rs780233345	chr3	189526258	189526258	G	A	exonic	TP63	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,UCEC\|1\|248\|0.00403
rs558374141	chr3	189590736	189590736	C	T	exonic	TP63	nonsynonymous	LIHC\|1\|373\|0.00268,SKCM\|1\|368\|0.00272
-	chr3	189455580	189455580	C	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189526167	189526167	C	T	exonic	TP63	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	189612091	189612091	C	T	exonic	TP63	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr3	189456558	189456558	A	T	exonic	TP63	nonsynonymous	OV\|1\|469\|0.00213
rs754361670	chr3	189455576	189455576	G	A	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272,UCEC\|1\|248\|0.00403
-	chr3	189526279	189526279	C	T	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189582083	189582083	G	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272
-	chr3	189526224	189526224	C	T	exonic	TP63	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr3	189597922	189597922	C	T	exonic	TP63	synonymous	BLCA\|1\|396\|0.00253
-	chr3	189582193	189582193	G	A	exonic	TP63	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	189526299	189526299	A	T	exonic	TP63	nonsynonymous	CESC\|1\|194\|0.00515
-	chr3	189455532	189455532	C	T	exonic	TP63	synonymous	SKCM\|2\|368\|0.00543,UCEC\|2\|248\|0.00806
rs193287780	chr3	189526122	189526122	C	T	exonic	TP63	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	189607226	189607226	C	A	exonic	TP63	synonymous	SKCM\|1\|368\|0.00272

Disease information of TP63

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TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
TP63	Multiple congenital anomalies	C16	Congenital Abnormality	CTD_human
TP63	Adenocarcinoma	C04	Neoplastic Process	CTD_human
TP63	Amelogenesis Imperfecta	C07;C16	Congenital Abnormality	GENOMICS_ENGLAND
TP63	Bladder Exstrophy	C12;C13;C16	Disease or Syndrome	ORPHANET
TP63	Breast Diseases	C17	Disease or Syndrome	CTD_human
TP63	Carcinoma	C04	Neoplastic Process	CTD_human
TP63	Malignant tumor of colon	C04;C06	Neoplastic Process	UNIPROT
TP63	Squamous cell carcinoma	C04	Neoplastic Process	CTD_human
TP63	Neoplastic Cell Transformation	C04;C23	Neoplastic Process	CTD_human
TP63	Cleft upper lip	C07;C16	Congenital Abnormality	CTD_human;ORPHANET
TP63	Cleft Palate	C05;C07;C16	Congenital Abnormality	CTD_human
TP63	Colorectal Carcinoma	C04;C06	Neoplastic Process	CTD_human
TP63	Colorectal Neoplasms	C04;C06	Neoplastic Process	CTD_human
TP63	Congenital Foot Deformity	C05;C16	Congenital Abnormality	CTD_human
TP63	Congenital Hand Deformities	C05;C16	Congenital Abnormality	CTD_human
TP63	Lung Neoplasms	C04;C08	Neoplastic Process	CTD_human
TP63	Neoplasm Metastasis	C04;C23	Neoplastic Process	CTD_human
TP63	Pancreatic Neoplasm	C04;C06;C19	Neoplastic Process	CTD_human
TP63	Skin Abnormalities	C16;C17	Congenital Abnormality	CTD_human
TP63	Sweat Gland Neoplasms	C04;C17	Neoplastic Process	CTD_human
TP63	Adenocarcinoma of lung (disorder)	C04;C08	Neoplastic Process	CTD_human
TP63	Cleft palate with cleft lip		Congenital Abnormality	ORPHANET
TP63	Adenocarcinoma, Basal Cell	C04	Neoplastic Process	CTD_human
TP63	Adenocarcinoma, Oxyphilic	C04	Neoplastic Process	CTD_human
TP63	Carcinoma, Cribriform	C04	Neoplastic Process	CTD_human
TP63	Carcinoma, Granular Cell	C04	Neoplastic Process	CTD_human
TP63	Adenocarcinoma, Tubular	C04	Neoplastic Process	CTD_human
TP63	Anaplastic carcinoma	C04	Neoplastic Process	CTD_human
TP63	Carcinoma, Spindle-Cell	C04	Neoplastic Process	CTD_human
TP63	Undifferentiated carcinoma	C04	Neoplastic Process	CTD_human
TP63	Carcinomatosis	C04	Neoplastic Process	CTD_human
TP63	Squamous Cell Neoplasms	C04	Neoplastic Process	CTD_human
TP63	Limb Deformities, Congenital	C05;C16	Congenital Abnormality	CTD_human
TP63	Malignant neoplasm of lung	C04;C08	Neoplastic Process	CTD_human
TP63	Ectrodactyly	C05;C16	Congenital Abnormality	ORPHANET
TP63	Malignant neoplasm of pancreas	C04;C06;C19	Neoplastic Process	CTD_human
TP63	Craniofacial Abnormalities	C05;C16	Congenital Abnormality	CTD_human
TP63	Rudiger syndrome 1	C05;C07;C16;C17	Disease or Syndrome	CTD_human;ORPHANET
TP63	Hay-Wells syndrome	C05;C07;C11;C16;C17	Congenital Abnormality	CTD_human;UNIPROT
TP63	Carcinoma of lung		Neoplastic Process	UNIPROT
TP63	Cancer of Neck	C04	Neoplastic Process	UNIPROT
TP63	Malignant Squamous Cell Neoplasm	C04	Neoplastic Process	CTD_human
TP63	ovarian neoplasm	C04;C13;C19	Neoplastic Process	CTD_human
TP63	Malignant neoplasm of ovary	C04;C13;C19	Neoplastic Process	CTD_human;UNIPROT
TP63	Cleft lip and alveolus		Congenital Abnormality	ORPHANET
TP63	Endocrine Breast Diseases	C17	Disease or Syndrome	CTD_human
TP63	Colorectal Cancer	C04;C06	Neoplastic Process	CTD_human
TP63	Female Urogenital Diseases	C13	Disease or Syndrome	CTD_human
TP63	RAPP-HODGKIN SYNDROME	C05;C07;C16;C17	Disease or Syndrome	CTD_human;ORPHANET;UNIPROT
TP63	Cleft palate, isolated	C05;C07;C16	Congenital Abnormality	CTD_human
TP63	PEELING SKIN SYNDROME	C16;C17	Disease or Syndrome	GENOMICS_ENGLAND
TP63	ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 1	C05;C07;C16;C17	Disease or Syndrome	ORPHANET
TP63	OROFACIAL CLEFT 8	C05;C07;C16	Disease or Syndrome	UNIPROT
TP63	Cleft Lip with or without Cleft Palate, Nonsyndromic, 8	C07;C16;C17	Disease or Syndrome	UNIPROT
TP63	SPLIT-HAND/FOOT MALFORMATION 4	C05;C16	Disease or Syndrome	CTD_human;UNIPROT
TP63	ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 3	C05;C07;C16;C17	Disease or Syndrome	CTD_human;UNIPROT
TP63	ADULT SYNDROME	C05;C07;C11;C16;C17;C23	Disease or Syndrome	CTD_human;ORPHANET;UNIPROT
TP63	LIMB-MAMMARY SYNDROME	C05;C16	Disease or Syndrome	CTD_human;ORPHANET
TP63	Intellectual Disability	C10;C23;F01;F03	Mental or Behavioral Dysfunction	GENOMICS_ENGLAND
TP63	cervical cancer	C04;C13	Neoplastic Process	UNIPROT

Pathway associated with TP63

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pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0000075	Activation of PUMA and translocation to mitochondria	reactome	8	24
pathway0001577	p53 pathway by glucose deprivation	panther	21	124
pathway0001578	p53 pathway	panther	39	274
pathway0001580	P53 pathway feedback loops 1	panther	6	16
pathway0001581	p53 pathway feedback loops 2	panther	42	372
pathway0001864	Regulation of TP53 Activity through Association with Co-factors	reactome	14	26
pathway0002271	TP53 Regulates Transcription of Caspase Activators and Caspases	reactome	12	33
pathway0002272	TP53 Regulates Transcription of Death Receptors and Ligands	reactome	12	29
pathway0002274	TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	reactome	19	53
pathway0002277	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	reactome	14	26
pathway0002393	Validated transcriptional targets of deltaNp63 isoforms	pid	47	101
pathway0002702	Hs_Focal_Adhesion_WP306_80308	wikipathways	26	68
pathway0002758	Hs_TGF-beta_Receptor_Signaling_WP560_90187	wikipathways	28	32
pathway0002843	Hs_Urea_cycle_and_metabolism_of_amino_groups_WP497_72142	wikipathways	8	7
pathway0002849	Hs_Hypothetical_Craniofacial_Development_Pathway_WP3655_88473	wikipathways	5	6

Go term information of TP63

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GO_term_name	GO_term_type	TF_name
GO_MULTICELLULAR_ORGANISM_AGING	BP	TP63
GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE_BY_P53_CLASS_MEDIATOR	BP	TP63
GO_MUSCLE_TISSUE_DEVELOPMENT	BP	TP63
GO_EPIDERMIS_MORPHOGENESIS	BP	TP63
GO_REGULATION_OF_CELLULAR_SENESCENCE	BP	TP63
GO_PROTEIN_HOMOTETRAMERIZATION	BP	TP63
GO_PROSTATE_GLAND_MORPHOGENESIS	BP	TP63
GO_REGULATION_OF_EPIDERMIS_DEVELOPMENT	BP	TP63
GO_KERATINOCYTE_PROLIFERATION	BP	TP63
GO_POSITIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY	BP	TP63
GO_REGULATION_OF_PROTEIN_INSERTION_INTO_MITOCHONDRIAL_MEMBRANE_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY	BP	TP63
GO_REGULATION_OF_WATER_LOSS_VIA_SKIN	BP	TP63
GO_POSITIVE_REGULATION_OF_CELL_PROLIFERATION	BP	TP63
GO_NEGATIVE_REGULATION_OF_CELL_AGING	BP	TP63
GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION	BP	TP63
GO_SEXUAL_REPRODUCTION	BP	TP63
GO_ORGAN_FORMATION	BP	TP63
GO_PROXIMAL_DISTAL_PATTERN_FORMATION	BP	TP63
GO_SMOOTH_MUSCLE_TISSUE_DEVELOPMENT	BP	TP63
GO_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION	BP	TP63
GO_MORPHOGENESIS_OF_AN_EPITHELIAL_FOLD	BP	TP63
GO_REGULATION_OF_FIBROBLAST_APOPTOTIC_PROCESS	BP	TP63
GO_REGULATION_OF_MESODERM_DEVELOPMENT	BP	TP63
GO_REGULATION_OF_KERATINOCYTE_PROLIFERATION	BP	TP63
GO_ESTABLISHMENT_OF_TISSUE_POLARITY	BP	TP63
GO_REGULATION_OF_NEURON_APOPTOTIC_PROCESS	BP	TP63
GO_POLARIZED_EPITHELIAL_CELL_DIFFERENTIATION	BP	TP63
GO_SYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT	BP	TP63
GO_MULTICELLULAR_ORGANISMAL_WATER_HOMEOSTASIS	BP	TP63
GO_RESPONSE_TO_UV	BP	TP63
GO_NOTCH_SIGNALING_PATHWAY	BP	TP63
GO_FEMALE_SEX_DIFFERENTIATION	BP	TP63
GO_MOLTING_CYCLE	BP	TP63
GO_NEGATIVE_REGULATION_OF_EPIDERMIS_DEVELOPMENT	BP	TP63
GO_REGULATION_OF_NOTCH_SIGNALING_PATHWAY	BP	TP63
GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR	BP	TP63
GO_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION	BP	TP63
GO_NEURON_APOPTOTIC_PROCESS	BP	TP63
GO_NEGATIVE_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION	BP	TP63
GO_NEGATIVE_REGULATION_OF_CELLULAR_SENESCENCE	BP	TP63
GO_REGULATION_OF_STEM_CELL_PROLIFERATION	BP	TP63
GO_CELLULAR_RESPONSE_TO_RADIATION	BP	TP63
GO_MULTICELLULAR_ORGANISMAL_HOMEOSTASIS	BP	TP63
GO_CELL_AGING	BP	TP63
GO_PROTEIN_HOMOOLIGOMERIZATION	BP	TP63
GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION	BP	TP63
GO_RESPONSE_TO_GAMMA_RADIATION	BP	TP63
GO_REGULATION_OF_KERATINOCYTE_DIFFERENTIATION	BP	TP63
GO_MORPHOGENESIS_OF_A_POLARIZED_EPITHELIUM	BP	TP63
GO_AUTONOMIC_NERVOUS_SYSTEM_DEVELOPMENT	BP	TP63
GO_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION	BP	TP63
GO_POSITIVE_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION	BP	TP63
GO_TUBE_MORPHOGENESIS	BP	TP63
GO_RESPONSE_TO_X_RAY	BP	TP63
GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_OUTER_MEMBRANE_PERMEABILIZATION_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY	BP	TP63
GO_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_PROSTATE_GLAND_DEVELOPMENT	BP	TP63
GO_PROSTATE_GLAND_DEVELOPMENT	BP	TP63
GO_POST_ANAL_TAIL_MORPHOGENESIS	BP	TP63
GO_NEURON_DEATH	BP	TP63
GO_REGULATION_OF_MEMBRANE_PERMEABILITY	BP	TP63
GO_POSITIVE_REGULATION_OF_STEM_CELL_PROLIFERATION	BP	TP63
GO_GENITALIA_DEVELOPMENT	BP	TP63
GO_PROSTATE_GLANDULAR_ACINUS_DEVELOPMENT	BP	TP63
GO_FEMALE_GENITALIA_DEVELOPMENT	BP	TP63
GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION	BP	TP63
GO_PROTEIN_TETRAMERIZATION	BP	TP63
GO_REGULATION_OF_MITOTIC_CELL_CYCLE	BP	TP63
GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION	BP	TP63
GO_NEGATIVE_REGULATION_OF_CELL_CYCLE	BP	TP63
GO_REGULATION_OF_CELL_AGING	BP	TP63
GO_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_RESULTING_IN_TRANSCRIPTION	BP	TP63
GO_ODONTOGENESIS	BP	TP63
GO_GLANDULAR_EPITHELIAL_CELL_DIFFERENTIATION	BP	TP63
GO_POSITIVE_REGULATION_OF_OSSIFICATION	BP	TP63
GO_NEURON_PART	CC	TP63
GO_ROUGH_ENDOPLASMIC_RETICULUM	CC	TP63
GO_WW_DOMAIN_BINDING	MF	TP63
GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING	MF	TP63
GO_CHROMATIN_BINDING	MF	TP63

Survival analysis of TP63

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of TP63

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)