Sample overview of Calu-3

Sample ID: Sample_02_080
Biosample type: Cell line
Tissue type: Lung
Biosample name: Calu-3
Data source: NCBI GEO/SRA
GSE ID: GSE63398
Cancer type: Lung adenocarcinoma
CRC number: 22
TF number of all CRCs: 20
TF list of all CRCs: SMAD3, FOXA1, HNF1B, ELF3, RARA, KLF5, EHF, ETS2, TGIF1, MECOM, JUNB, BHLHE40, TFAP2A, NR2F2, HES1, ELK4, FOXC2, FOXL1, MYC, ONECUT2

The most representative CRC of Calu-3
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Relationship plot of CRC model
TF number of this CRC: 9
CRC socre: 15.66667
TF list of the most representative CRC
TF name TF family Frequency of TFs
EHF ETS 10 / 22
ELF3 ETS 22 / 22
ETS2 ETS 10 / 22
FOXA1 Fork_head 22 / 22
HNF1B Homeobox 22 / 22
JUNB TF_bZIP 8 / 22
MECOM zf-C2H2 9 / 22
RARA THR-like 16 / 22
SMAD3 MH1 22 / 22

All CRCs of Calu-3
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
ELF3 22 / 22 ETS ENSG00000163435
FOXA1 22 / 22 Fork_head ENSG00000129514
HNF1B 22 / 22 Homeobox ENSG00000275410
SMAD3 22 / 22 MH1 ENSG00000166949
RARA 16 / 22 THR-like ENSG00000131759
KLF5 12 / 22 zf-C2H2 ENSG00000102554
EHF 10 / 22 ETS ENSG00000135373
ETS2 10 / 22 ETS ENSG00000157557
TGIF1 10 / 22 Homeobox ENSG00000177426
MECOM 9 / 22 zf-C2H2 ENSG00000085276
JUNB 8 / 22 TF_bZIP ENSG00000171223
BHLHE40 7 / 22 bHLH ENSG00000134107
NR2F2 7 / 22 RXR-like ENSG00000185551
TFAP2A 7 / 22 AP-2 ENSG00000137203
ELK4 5 / 22 ETS ENSG00000158711
HES1 5 / 22 bHLH ENSG00000114315
FOXC2 4 / 22 Fork_head ENSG00000176692
FOXL1 4 / 22 Fork_head ENSG00000176678
MYC 3 / 22 bHLH ENSG00000136997
ONECUT2 2 / 22 CUT ENSG00000119547

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
FOXA1 27 33 60
SMAD3 26 35 61
BHLHE40 24 27 51
ELF3 26 34 60
RARA 25 33 58
HNF1B 25 34 59
TFAP2A 19 36 55
MECOM 27 25 52
NR2F2 23 28 51
ETS2 27 21 48
KLF5 25 33 58
ONECUT2 24 25 49
MYC 18 28 46
JUNB 25 29 54
EHF 23 35 58
FOXL1 15 34 49
ELK4 21 26 47
HES1 25 22 47
FOXC2 15 35 50
TGIF1 22 31 53

Expression of TFs in all CRCs