Cancer CRCdb

Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_080	Cell line	Lung	Calu-3	0.090909090909091

Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of ONECUT2

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr18	55143790	55143790	C	T	exonic	ONECUT2	synonymous	SKCM\|1\|368\|0.00272
-	chr18	55104004	55104004	C	T	exonic	ONECUT2	synonymous	SKCM\|1\|368\|0.00272
-	chr18	55104091	55104091	C	T	exonic	ONECUT2	synonymous	SKCM\|1\|368\|0.00272
-	chr18	55102969	55102969	C	G	exonic	ONECUT2	synonymous	UCS\|1\|57\|0.01754
-	chr18	55103687	55103687	C	T	exonic	ONECUT2	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr18	55103244	55103245	CG	-	exonic	ONECUT2	frameshift	PRAD\|1\|499\|0.00200
rs753408085	chr18	55103827	55103827	C	T	exonic	ONECUT2	synonymous	ESCA\|1\|185\|0.00541
-	chr18	55103932	55103932	C	T	exonic	ONECUT2	synonymous	UCEC\|1\|248\|0.00403
-	chr18	55103234	55103234	G	T	exonic	ONECUT2	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr18	55103278	55103278	G	T	exonic	ONECUT2	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr18	55103544	55103544	G	C	exonic	ONECUT2	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr18	55143683	55143683	G	C	exonic	ONECUT2	nonsynonymous	CESC\|1\|194\|0.00515
rs767911692	chr18	55143925	55143925	G	A	exonic	ONECUT2	synonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
rs765657446	chr18	55143901	55143901	C	T	exonic	ONECUT2	synonymous	HNSC\|2\|512\|0.00391
-	chr18	55103683	55103683	T	C	exonic	ONECUT2	synonymous	LUAD\|2\|543\|0.00368
-	chr18	55143726	55143726	C	T	exonic	ONECUT2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr18	55143772	55143772	C	T	exonic	ONECUT2	synonymous	BLCA\|1\|396\|0.00253
-	chr18	55103907	55103907	C	T	exonic	ONECUT2	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr18	55143779	55143779	G	A	exonic	ONECUT2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr18	55143772	55143772	C	G	exonic	ONECUT2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr18	55104096	55104096	C	T	exonic	ONECUT2	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr18	55103632	55103632	C	T	exonic	ONECUT2	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr18	55103371	55103371	C	T	exonic	ONECUT2	synonymous	UCEC\|1\|248\|0.00403
-	chr18	55104056	55104056	G	T	exonic	ONECUT2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr18	55104121	55104121	G	T	exonic	ONECUT2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr18	55103474	55103474	C	T	exonic	ONECUT2	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr18	55143765	55143765	T	C	exonic	ONECUT2	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr18	55104010	55104010	G	A	exonic	ONECUT2	synonymous	SKCM\|1\|368\|0.00272
-	chr18	55143819	55143819	C	T	exonic	ONECUT2	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr18	55103476	55103476	-	AC	exonic	ONECUT2	frameshift	BRCA\|1\|982\|0.00102,DLBC\|1\|48\|0.02083,UCEC\|1\|248\|0.00403
rs755413489	chr18	55143788	55143788	C	T	exonic	ONECUT2	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr18	55103358	55103358	C	T	exonic	ONECUT2	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
rs577405693	chr18	55103659	55103659	C	T	exonic	ONECUT2	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr18	55143876	55143876	G	A	exonic	ONECUT2	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr18	55143905	55143905	C	G	exonic	ONECUT2	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr18	55103907	55103907	C	A	exonic	ONECUT2	stopgain	LUAD\|1\|543\|0.00184
rs771314671	chr18	55143878	55143878	C	T	exonic	ONECUT2	nonsynonymous	CESC\|1\|194\|0.00515
-	chr18	55103988	55103988	A	G	exonic	ONECUT2	nonsynonymous	HNSC\|1\|512\|0.00195
rs769761027	chr18	55143848	55143848	G	A	exonic	ONECUT2	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122,KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr18	55103710	55103710	C	T	exonic	ONECUT2	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr18	55104151	55104151	G	C	exonic	ONECUT2	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr18	55103586	55103586	C	T	exonic	ONECUT2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr18	55143778	55143778	G	A	exonic	ONECUT2	synonymous	SKCM\|1\|368\|0.00272
-	chr18	55103946	55103947	TC	-	exonic	ONECUT2	frameshift	CHOL\|1\|35\|0.02857
-	chr18	55143862	55143862	C	T	exonic	ONECUT2	synonymous	SKCM\|3\|368\|0.00815
rs3745073	chr18	55143924	55143924	C	T	exonic	ONECUT2	nonsynonymous	SKCM\|1\|368\|0.00272,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs375937685	chr18	55103370	55103370	G	T	exonic	ONECUT2	nonsynonymous	PAAD\|1\|185\|0.00541
rs749300131	chr18	55103734	55103734	C	T	exonic	ONECUT2	synonymous	UCEC\|1\|248\|0.00403
-	chr18	55103350	55103350	C	T	exonic	ONECUT2	synonymous	DLBC\|1\|48\|0.02083
rs777247557	chr18	55143879	55143879	G	A	exonic	ONECUT2	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr18	55143730	55143730	C	T	exonic	ONECUT2	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr18	55103329	55103329	G	A	exonic	ONECUT2	synonymous	LUAD\|1\|543\|0.00184
-	chr18	55103824	55103824	G	C	exonic	ONECUT2	synonymous	HNSC\|1\|512\|0.00195
-	chr18	55103008	55103008	G	A	exonic	ONECUT2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr18	55103430	55103430	C	G	exonic	ONECUT2	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr18	55103647	55103647	C	T	exonic	ONECUT2	synonymous	LUAD\|1\|543\|0.00184
rs778610599	chr18	55103457	55103457	C	T	exonic	ONECUT2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr18	55104053	55104053	T	A	exonic	ONECUT2	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr18	55143919	55143919	C	T	exonic	ONECUT2	synonymous	UCEC\|1\|248\|0.00403
-	chr18	55103486	55103486	C	T	exonic	ONECUT2	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr18	55143902	55143902	G	A	exonic	ONECUT2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr18	55143734	55143734	G	T	exonic	ONECUT2	nonsynonymous	LUAD\|1\|543\|0.00184
rs767035885	chr18	55103799	55103799	C	T	exonic	ONECUT2	nonsynonymous	SKCM\|1\|368\|0.00272
rs572113702	chr18	55143669	55143669	C	T	exonic	ONECUT2	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr18	55103898	55103898	C	A	exonic	ONECUT2	stopgain	CESC\|1\|194\|0.00515
rs756746181	chr18	55103650	55103650	C	T	exonic	ONECUT2	synonymous	TGCT\|1\|155\|0.00645
-	chr18	55143752	55143752	C	T	exonic	ONECUT2	nonsynonymous	BLCA\|1\|396\|0.00253,OV\|1\|469\|0.00213,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr18	55102980	55102980	T	C	exonic	ONECUT2	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr18	55103949	55103949	A	G	exonic	ONECUT2	nonsynonymous	TGCT\|1\|155\|0.00645
-	chr18	55103312	55103312	G	C	exonic	ONECUT2	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr18	55103602	55103602	C	A	exonic	ONECUT2	synonymous	BLCA\|1\|396\|0.00253
rs760843135	chr18	55143875	55143875	C	T	exonic	ONECUT2	nonsynonymous	BRCA\|2\|982\|0.00204
-	chr18	55103728	55103728	C	T	exonic	ONECUT2	synonymous	LIHC\|1\|373\|0.00268
-	chr18	55104035	55104035	C	T	exonic	ONECUT2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr18	55103397	55103397	C	T	exonic	ONECUT2	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr18	55143727	55143727	C	T	exonic	ONECUT2	synonymous	SKCM\|1\|368\|0.00272
-	chr18	55103478	55103479	AC	-	exonic	ONECUT2	frameshift	BRCA\|1\|982\|0.00102,LUAD\|1\|543\|0.00184,PAAD\|4\|185\|0.02162,PRAD\|2\|499\|0.00401,SKCM\|1\|368\|0.00272
-	chr18	55143729	55143729	G	A	exonic	ONECUT2	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122,OV\|1\|469\|0.00213,UCEC\|1\|248\|0.00403
rs186386413	chr18	55103500	55103500	C	G	exonic	ONECUT2	nonsynonymous	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr18	55104001	55104001	C	-	exonic	ONECUT2	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253

TF name:	ONECUT2
TF family:	CUT
Ensembl gene ID:	ENSG00000119547
Ensembl protein ID:	ENSP00000419185
Entrez gene ID:	9480

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

GO_term_name	GO_term_type	TF_name
GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS	BP	ONECUT2
GO_CELL_PROJECTION_ASSEMBLY	BP	ONECUT2
GO_PANCREAS_DEVELOPMENT	BP	ONECUT2
GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS	BP	ONECUT2
GO_CELLULAR_COMPONENT_ASSEMBLY_INVOLVED_IN_MORPHOGENESIS	BP	ONECUT2
GO_PERIPHERAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION	BP	ONECUT2
GO_ENDOCRINE_PANCREAS_DEVELOPMENT	BP	ONECUT2
GO_REGULATION_OF_CELL_SUBSTRATE_ADHESION	BP	ONECUT2
GO_CELL_FATE_COMMITMENT	BP	ONECUT2
GO_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY	BP	ONECUT2
GO_DOUBLE_STRANDED_DNA_BINDING	MF	ONECUT2

TF information

TCGA somatic mutations and clinical variants of ONECUT2

Survival analysis of ONECUT2

Expression of ONECUT2