Cancer CRCdb

TF information

TF name:	HNF1B
TF family:	Homeobox
Ensembl gene ID:	ENSG00000275410
Ensembl protein ID:	ENSP00000482529, ENSP00000480291, ENSP00000482711, ENSP00000477524, ENSP00000478682
Entrez gene ID:	6928

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of HNF1B in all biosamples

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Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_01_001	Cell line	Prostate	22Rv1	0.31719128329298
Sample_02_080	Cell line	Lung	Calu-3	1
Sample_02_192	Cell line	Stomach	MKN45	0.5
Sample_02_237	Cell line	Colon	V389	0.57003497147064
Sample_02_241	Cell line	Colon	V456	0.25846501128668
Sample_02_267	Cell line	Kidney	786-O	0.4
Sample_02_354	Cell line	Colon	Colo205	0.36186186186186
Sample_02_361	Cell line	Colon	HT29_DMSO	0.092035398230088
Sample_02_430	Cell line	Kidney	12364284	0.875

HNF1B distribution in samples’ most representative CRC

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Sample ID	Tissue type	Biosample type	Biosample name
Sample_01_001	Prostate	Cell line	22Rv1
Sample_02_080	Lung	Cell line	Calu-3
Sample_02_192	Stomach	Cell line	MKN45
Sample_02_237	Colon	Cell line	V389
Sample_02_354	Colon	Cell line	Colo205
Sample_02_430	Kidney	Cell line	12364284

HNF1B distribution in all CRCs

Genomic distribution of SEs associated with HNF1B

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Mutation of HNF1B

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Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of HNF1B

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr17	36064986	36064986	T	G	exonic	HNF1B	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr17	36104586	36104586	G	A	exonic	HNF1B	nonsynonymous	SARC\|1\|247\|0.00405
-	chr17	36091616	36091616	G	T	exonic	HNF1B	nonsynonymous	SARC\|1\|247\|0.00405
-	chr17	36070626	36070626	G	A	exonic	HNF1B	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr17	36047338	36047338	C	T	UTR3	HNF1B	unknown	SKCM\|1\|368\|0.00272
-	chr17	36091686	36091686	-	T	exonic	HNF1B	frameshift	PAAD\|1\|185\|0.00541
rs764285484	chr17	36047316	36047316	G	A	UTR3	HNF1B	unknown	SKCM\|2\|368\|0.00543
-	chr17	36093716	36093716	C	G	exonic	HNF1B	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr17	36099454	36099454	C	T	exonic	HNF1B	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr17	36065052	36065052	G	A	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	36091761	36091761	C	T	exonic	HNF1B	synonymous	SKCM\|1\|368\|0.00272
-	chr17	36093688	36093688	G	C	exonic	HNF1B	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr17	36104669	36104669	G	A	exonic	HNF1B	synonymous	BLCA\|1\|396\|0.00253
-	chr17	36093625	36093625	A	G	exonic	HNF1B	nonsynonymous	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409,OV\|1\|469\|0.00213
rs867882536	chr17	36093661	36093661	C	T	exonic	HNF1B	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr17	36091586	36091586	C	A	exonic	HNF1B	stopgain	OV\|1\|469\|0.00213
-	chr17	36091644	36091644	C	T	exonic	HNF1B	synonymous	HNSC\|1\|512\|0.00195
rs775094591	chr17	36070601	36070601	G	A	exonic	HNF1B	synonymous	HNSC\|1\|512\|0.00195
-	chr17	36059100	36059100	G	A	exonic	HNF1B	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs764042837	chr17	36059173	36059173	-	G	exonic	HNF1B	frameshift	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409,KIPAN\|4\|799\|0.00501,KIRC\|4\|451\|0.00887,LUAD\|8\|543\|0.01473,PAAD\|1\|185\|0.00541,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr17	36047047	36047057	TGTTCGATGAA	-	UTR3	HNF1B	unknown	-
-	chr17	36059118	36059118	G	T	exonic	HNF1B	nonsynonymous	CESC\|1\|194\|0.00515
-	chr17	36091725	36091725	G	C	exonic	HNF1B	nonsynonymous	KIPAN\|2\|799\|0.00250,KIRC\|2\|451\|0.00443
-	chr17	36091701	36091701	C	T	exonic	HNF1B	synonymous	SKCM\|1\|368\|0.00272
rs753220832	chr17	36070536	36070536	T	C	exonic	HNF1B	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr17	36104840	36104840	G	T	exonic	HNF1B	synonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
rs772737211	chr17	36047354	36047354	G	A	UTR3	HNF1B	unknown	SKCM\|2\|368\|0.00543,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr17	36091772	36091772	C	G	exonic	HNF1B	nonsynonymous	SARC\|1\|247\|0.00405
rs769477849	chr17	36059181	36059181	T	C	exonic	HNF1B	synonymous	SKCM\|1\|368\|0.00272
-	chr17	36099523	36099523	G	A	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	36093634	36093634	G	A	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	36093663	36093663	G	C	exonic	HNF1B	synonymous	PRAD\|1\|499\|0.00200
rs147218489	chr17	36099531	36099531	C	T	exonic	HNF1B	synonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506,UCEC\|1\|248\|0.00403
-	chr17	36093645	36093645	C	T	exonic	HNF1B	stopgain	SKCM\|1\|368\|0.00272
-	chr17	36093708	36093708	C	T	exonic	HNF1B	synonymous	SARC\|1\|247\|0.00405
-	chr17	36093584	36093584	C	G	exonic	HNF1B	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	36099509	36099510	TG	-	exonic	HNF1B	frameshift	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
-	chr17	36093780	36093780	C	T	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
rs776536485	chr17	36064925	36064925	T	C	exonic	HNF1B	synonymous	LUAD\|1\|543\|0.00184
-	chr17	36104534	36104534	G	A	exonic	HNF1B	synonymous	BLCA\|1\|396\|0.00253
-	chr17	36091655	36091655	G	A	exonic	HNF1B	synonymous	SKCM\|1\|368\|0.00272
rs753701914	chr17	36104758	36104758	C	G	exonic	HNF1B	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	36104728	36104728	G	T	exonic	HNF1B	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr17	36104852	36104852	G	A	exonic	HNF1B	synonymous	SKCM\|1\|368\|0.00272
-	chr17	36093787	36093787	C	T	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
rs764561297	chr17	36099459	36099459	G	A	exonic	HNF1B	synonymous	UCEC\|1\|248\|0.00403
-	chr17	36061117	36061117	G	T	exonic	HNF1B	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr17	36104535	36104535	A	G	exonic	HNF1B	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr17	36091585	36091585	C	T	splicing	HNF1B	splicing	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409
-	chr17	36070598	36070598	G	T	exonic	HNF1B	synonymous	LIHC\|1\|373\|0.00268
-	chr17	36091723	36091723	C	T	exonic	HNF1B	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr17	36091721	36091721	T	C	exonic	HNF1B	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr17	36099564	36099564	C	T	exonic	HNF1B	synonymous	SKCM\|2\|368\|0.00543
-	chr17	36091623	36091623	G	T	exonic	HNF1B	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr17	36059179	36059179	G	A	exonic	HNF1B	nonsynonymous	OV\|1\|469\|0.00213
-	chr17	36093800	36093800	C	A	exonic	HNF1B	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr17	36099510	36099511	TG	-	exonic	HNF1B	frameshift	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
-	chr17	36104670	36104680	TGGCCGTTGGT	-	exonic	HNF1B	frameshift	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr17	36099443	36099443	C	T	exonic	HNF1B	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr17	36099582	36099582	T	C	exonic	HNF1B	synonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr17	36070540	36070549	GGCCTGGGTC	-	exonic	HNF1B	frameshift	OV\|1\|469\|0.00213
-	chr17	36093605	36093605	G	T	exonic	HNF1B	synonymous	LUSC\|1\|178\|0.00562
-	chr17	36099473	36099473	G	C	exonic	HNF1B	nonsynonymous	CESC\|1\|194\|0.00515
-	chr17	36070615	36070615	G	A	exonic	HNF1B	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr17	36064997	36064997	G	A	exonic	HNF1B	synonymous	SKCM\|1\|368\|0.00272
-	chr17	36099519	36099519	C	T	exonic	HNF1B	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs377555356	chr17	36093701	36093701	C	T	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	36091778	36091778	C	T	exonic	HNF1B	nonsynonymous	PRAD\|1\|499\|0.00200,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr17	36093584	36093584	C	T	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	36104543	36104543	G	A	exonic	HNF1B	synonymous	HNSC\|1\|512\|0.00195
-	chr17	36093776	36093776	C	T	exonic	HNF1B	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	36059152	36059152	A	G	exonic	HNF1B	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr17	36093623	36093623	A	G	exonic	HNF1B	synonymous	BLCA\|1\|396\|0.00253
-	chr17	36064972	36064972	G	C	exonic	HNF1B	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr17	36065033	36065033	C	A	exonic	HNF1B	nonsynonymous	PAAD\|1\|185\|0.00541
rs780554506	chr17	36059196	36059196	G	A	exonic	HNF1B	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr17	36065013	36065013	G	A	exonic	HNF1B	nonsynonymous	GBM\|2\|290\|0.00690,GBMLGG\|2\|820\|0.00244
-	chr17	36064935	36064935	G	C	exonic	HNF1B	nonsynonymous	HNSC\|1\|512\|0.00195
rs757452269	chr17	36099476	36099476	C	T	exonic	HNF1B	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr17	36091619	36091619	G	A	exonic	HNF1B	stopgain	LIHC\|1\|373\|0.00268
-	chr17	36093664	36093664	C	A	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	36065026	36065026	C	A	exonic	HNF1B	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr17	36104746	36104746	C	G	exonic	HNF1B	nonsynonymous	CESC\|1\|194\|0.00515
-	chr17	36064984	36064984	G	A	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	36091719	36091719	C	T	exonic	HNF1B	synonymous	SKCM\|1\|368\|0.00272
-	chr17	36093778	36093778	G	C	exonic	HNF1B	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	36059174	36059174	G	-	exonic	HNF1B	frameshift	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr17	36070546	36070555	GGTCCAGGCT	-	exonic	HNF1B	frameshift	UCEC\|1\|248\|0.00403
rs148713761	chr17	36093702	36093702	G	A	exonic	HNF1B	synonymous	CESC\|1\|194\|0.00515
-	chr17	36104797	36104797	C	A	exonic	HNF1B	nonsynonymous	LUAD\|1\|543\|0.00184
rs866277746	chr17	36099554	36099554	C	T	exonic	HNF1B	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	36099441	36099441	C	T	exonic	HNF1B	synonymous	SKCM\|1\|368\|0.00272
-	chr17	36099431	36099431	G	A	exonic	HNF1B	stopgain	BRCA\|1\|982\|0.00102,PCPG\|1\|184\|0.00543
-	chr17	36091630	36091630	G	A	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	36093613	36093613	G	T	exonic	HNF1B	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr17	36104627	36104627	G	T	exonic	HNF1B	synonymous	TGCT\|1\|155\|0.00645
-	chr17	36099603	36099603	C	T	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	36059119	36059119	C	A	exonic	HNF1B	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr17	36061037	36061037	C	T	exonic	HNF1B	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr17	36093664	36093664	C	T	exonic	HNF1B	nonsynonymous	OV\|1\|469\|0.00213
-	chr17	36065015	36065015	C	T	exonic	HNF1B	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253

Disease information of HNF1B

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TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
HNF1B	Renal Cell Carcinoma	C04;C12;C13	Neoplastic Process	CTD_human
HNF1B	Cholestasis	C06	Disease or Syndrome	GENOMICS_ENGLAND
HNF1B	Diabetes Mellitus, Non-Insulin-Dependent	C18;C19	Disease or Syndrome	CTD_human;UNIPROT
HNF1B	Prostatic Neoplasms	C04;C12	Neoplastic Process	CTD_human
HNF1B	Conventional (Clear Cell) Renal Cell Carcinoma	C04;C12;C13	Neoplastic Process	CTD_human
HNF1B	Malignant neoplasm of prostate	C04;C12	Neoplastic Process	CTD_human
HNF1B	Renal cysts and diabetes syndrome	C10;C12;C13;C18;C19	Disease or Syndrome	CTD_human;ORPHANET;UNIPROT
HNF1B	Cholestasis in newborn		Disease or Syndrome	GENOMICS_ENGLAND
HNF1B	Chromophobe Renal Cell Carcinoma	C04;C12;C13	Neoplastic Process	CTD_human
HNF1B	Sarcomatoid Renal Cell Carcinoma	C04;C12;C13	Neoplastic Process	CTD_human
HNF1B	Collecting Duct Carcinoma of the Kidney	C04;C12;C13	Neoplastic Process	CTD_human
HNF1B	Papillary Renal Cell Carcinoma	C04;C12;C13	Neoplastic Process	CTD_human
HNF1B	Unilateral Multicystic Dysplastic Kidney	C12;C13;C16	Congenital Abnormality; Disease or Syndrome	ORPHANET
HNF1B	Bilateral Multicystic Dysplastic Kidneys	C12;C13;C16	Congenital Abnormality; Disease or Syndrome	ORPHANET
HNF1B	Cystic Kidney Diseases	C12;C13	Disease or Syndrome	GENOMICS_ENGLAND
HNF1B	Hypomagnesemia 2, renal	C12;C13;C16;C18	Disease or Syndrome	ORPHANET
HNF1B	MULTICYSTIC RENAL DYSPLASIA, BILATERAL	C12;C13;C16	Disease or Syndrome	ORPHANET
HNF1B	INSULIN RESISTANCE, SUSCEPTIBILITY TO		Finding	UNIPROT
HNF1B	Cakut	C12;C13;C16	Disease or Syndrome	GENOMICS_ENGLAND
HNF1B	Prostate cancer, familial	C04;C12	Neoplastic Process	ORPHANET
HNF1B	CHROMOSOME 17q12 DELETION SYNDROME		Disease or Syndrome	ORPHANET
HNF1B	DIABETES MELLITUS, TYPE 2, PROTECTION AGAINST		Finding	UNIPROT
HNF1B	Ciliopathies	C16	Congenital Abnormality	GENOMICS_ENGLAND

Pathway associated with HNF1B

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pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0001835	Regulation of gene expression in early pancreatic precursor cells	reactome	8	8
pathway0001837	Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	reactome	7	9
pathway0002631	Maturity onset diabetes of the young	kegg	25	76

Go term information of HNF1B

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GO_term_name	GO_term_type	TF_name
GO_NEGATIVE_REGULATION_OF_KIDNEY_DEVELOPMENT	BP	HNF1B
GO_REGULATION_OF_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE	BP	HNF1B
GO_AMIDE_TRANSPORT	BP	HNF1B
GO_NEGATIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION	BP	HNF1B
GO_PROTEIN_SECRETION	BP	HNF1B
GO_POSITIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_INITIATION	BP	HNF1B
GO_INSULIN_SECRETION	BP	HNF1B
GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER	BP	HNF1B
GO_HORMONE_TRANSPORT	BP	HNF1B
GO_CIRCADIAN_REGULATION_OF_GENE_EXPRESSION	BP	HNF1B
GO_KIDNEY_EPITHELIUM_DEVELOPMENT	BP	HNF1B
GO_BLASTOCYST_FORMATION	BP	HNF1B
GO_PEPTIDE_SECRETION	BP	HNF1B
GO_MORPHOGENESIS_OF_EMBRYONIC_EPITHELIUM	BP	HNF1B
GO_REGULATION_OF_MESONEPHROS_DEVELOPMENT	BP	HNF1B
GO_PANCREAS_DEVELOPMENT	BP	HNF1B
GO_EMBRYONIC_DIGESTIVE_TRACT_MORPHOGENESIS	BP	HNF1B
GO_DIGESTIVE_SYSTEM_DEVELOPMENT	BP	HNF1B
GO_NEPHRIC_DUCT_DEVELOPMENT	BP	HNF1B
GO_REGULATION_OF_KIDNEY_DEVELOPMENT	BP	HNF1B
GO_CELL_FATE_COMMITMENT_INVOLVED_IN_FORMATION_OF_PRIMARY_GERM_LAYER	BP	HNF1B
GO_REGULATION_OF_MESENCHYMAL_CELL_APOPTOTIC_PROCESS	BP	HNF1B
GO_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION	BP	HNF1B
GO_NEPHRON_EPITHELIUM_DEVELOPMENT	BP	HNF1B
GO_EMBRYONIC_DIGESTIVE_TRACT_DEVELOPMENT	BP	HNF1B
GO_ENDOCRINE_PANCREAS_DEVELOPMENT	BP	HNF1B
GO_ENDODERMAL_CELL_DIFFERENTIATION	BP	HNF1B
GO_ORGAN_MORPHOGENESIS	BP	HNF1B
GO_DIGESTIVE_TRACT_MORPHOGENESIS	BP	HNF1B
GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_INITIATION	BP	HNF1B
GO_REGULATION_OF_CELL_DIFFERENTIATION	BP	HNF1B
GO_MESONEPHRIC_TUBULE_MORPHOGENESIS	BP	HNF1B
GO_BLASTOCYST_DEVELOPMENT	BP	HNF1B
GO_GASTRULATION	BP	HNF1B
GO_ENDODERM_DEVELOPMENT	BP	HNF1B
GO_REGULATION_OF_STEM_CELL_POPULATION_MAINTENANCE	BP	HNF1B
GO_REGULATION_OF_GASTRULATION	BP	HNF1B
GO_POSITIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY	BP	HNF1B
GO_REGULATION_OF_METANEPHROS_DEVELOPMENT	BP	HNF1B
GO_ENDODERM_FORMATION	BP	HNF1B
GO_EPITHELIAL_CELL_PROLIFERATION	BP	HNF1B
GO_REGULATION_OF_CELL_FATE_SPECIFICATION	BP	HNF1B
GO_CELL_FATE_SPECIFICATION	BP	HNF1B
GO_KIDNEY_MORPHOGENESIS	BP	HNF1B
GO_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS	BP	HNF1B
GO_NEPHRON_TUBULE_FORMATION	BP	HNF1B
GO_NEPHRON_DEVELOPMENT	BP	HNF1B
GO_GENITALIA_DEVELOPMENT	BP	HNF1B
GO_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE	BP	HNF1B
GO_MESONEPHROS_DEVELOPMENT	BP	HNF1B
GO_ENDODERMAL_CELL_FATE_COMMITMENT	BP	HNF1B
GO_NEPHRIC_DUCT_MORPHOGENESIS	BP	HNF1B
GO_PEPTIDE_TRANSPORT	BP	HNF1B
GO_REGULATION_OF_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER	BP	HNF1B
GO_REGULATION_OF_CELL_FATE_COMMITMENT	BP	HNF1B
GO_REGULATION_OF_STEM_CELL_DIFFERENTIATION	BP	HNF1B
GO_TRANSCRIPTION_FACTOR_COMPLEX	CC	HNF1B
GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_BINDING	MF	HNF1B
GO_NUCLEIC_ACID_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY	MF	HNF1B

Survival analysis of HNF1B

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of HNF1B

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)