Sample overview of 786-O

Sample ID: Sample_02_267
Biosample type: Cell line
Tissue type: Kidney
Biosample name: 786-O
Data source: NCBI GEO/SRA
GSE ID: GSE86087
Cancer type: clear cell renal cell carcinoma
CRC number: 10
TF number of all CRCs: 14
TF list of all CRCs: RARA, TCF7L2, SMAD3, FOSL2, SREBF1, RXRA, BHLHE40, TCF12, RUNX2, HNF1B, BHLHE41, FOXP1, CREB3L2, HOXB2

The most representative CRC of 786-O
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Relationship plot of CRC model
TF number of this CRC: 9
CRC socre: 7.666667
TF list of the most representative CRC
TF name TF family Frequency of TFs
BHLHE40 bHLH 6 / 10
FOSL2 TF_bZIP 8 / 10
RARA THR-like 10 / 10
RUNX2 Runt 5 / 10
RXRA RXR-like 6 / 10
SMAD3 MH1 10 / 10
SREBF1 bHLH 8 / 10
TCF12 bHLH 6 / 10
TCF7L2 HMG 10 / 10

All CRCs of 786-O
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
TCF7L2 10 / 10 HMG ENSG00000148737
RARA 10 / 10 THR-like ENSG00000131759
SMAD3 10 / 10 MH1 ENSG00000166949
FOSL2 8 / 10 TF_bZIP ENSG00000075426
SREBF1 8 / 10 bHLH ENSG00000072310
TCF12 6 / 10 bHLH ENSG00000140262
BHLHE40 6 / 10 bHLH ENSG00000134107
RXRA 6 / 10 RXR-like ENSG00000186350
RUNX2 5 / 10 Runt ENSG00000124813
HNF1B 4 / 10 Homeobox ENSG00000275410
BHLHE41 3 / 10 bHLH ENSG00000123095
CREB3L2 2 / 10 TF_bZIP ENSG00000182158
FOXP1 2 / 10 Fork_head ENSG00000114861
HOXB2 2 / 10 Homeobox ENSG00000173917

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
FOXP1 12 28 40
SMAD3 17 25 42
RARA 15 28 43
RUNX2 15 24 39
BHLHE40 18 23 41
BHLHE41 17 17 34
HNF1B 16 22 38
FOSL2 17 27 44
HOXB2 17 13 30
RXRA 14 27 41
TCF7L2 16 25 41
CREB3L2 15 19 34
SREBF1 17 24 41
TCF12 15 26 41

Expression of TFs in all CRCs