Cancer CRCdb

TF information

TF name:	FOXP1
TF family:	Fork_head
Ensembl gene ID:	ENSG00000114861
Ensembl protein ID:	ENSP00000482847, ENSP00000333560, ENSP00000484803, ENSP00000419393, ENSP00000417857, ENSP00000418524, ENSP00000418883, ENSP00000318902, ENSP00000418102, ENSP00000418225, ENSP00000420736
Entrez gene ID:	27086

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of FOXP1 in all biosamples

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Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_007	Other	Cervical	cervical-cancer_vector	0.086092715231788
Sample_02_021	Cell line	Colon	V429	0.49610838858461
Sample_02_164	Cell line	Lung	H2087_Parental	0.23333333333333
Sample_02_179	Cell line	Urinary bladder	T24	0.31034482758621
Sample_02_196	Cell line	Stomach	NCC59	0.85714285714286
Sample_02_204	Cell line	Stomach	IM95	0.72727272727273
Sample_02_205	Tissue	Stomach	Gastric_Primary_Sample_T	0.68148148148148
Sample_02_236	Cell line	Colon	V206	0.60041407867495
Sample_02_242	Cell line	Colon	V481	0.81010062167532
Sample_02_267	Cell line	Kidney	786-O	0.2
Sample_02_268	Cell line	Kidney	A-498	0.031198080118147
Sample_02_322	Cell line	Colon	Caco-2	0.68775235531629
Sample_02_361	Cell line	Colon	HT29_DMSO	0.55575221238938
Sample_02_430	Cell line	Kidney	12364284	0.375

FOXP1 distribution in samples’ most representative CRC

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Sample ID	Tissue type	Biosample type	Biosample name
Sample_02_179	Urinary bladder	Cell line	T24
Sample_02_196	Stomach	Cell line	NCC59
Sample_02_204	Stomach	Cell line	IM95
Sample_02_205	Stomach	Tissue	Gastric_Primary_Sample_T
Sample_02_236	Colon	Cell line	V206
Sample_02_242	Colon	Cell line	V481
Sample_02_322	Colon	Cell line	Caco-2

FOXP1 distribution in all CRCs

Genomic distribution of SEs associated with FOXP1

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Mutation of FOXP1

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Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of FOXP1

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
rs757649540	chr3	71247378	71247378	G	A	exonic	FOXP1	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr3	71021828	71021828	C	A	splicing	FOXP1	splicing	BLCA\|1\|396\|0.00253
rs797044652	chr3	71027086	71027086	-	G	exonic	FOXP1	frameshift	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222,LUAD\|1\|543\|0.00184
-	chr3	71026793	71026793	C	G	splicing	FOXP1	splicing	LAML\|1\|197\|0.00508
-	chr3	71008343	71008344	TT	-	UTR3	FOXP1	unknown	ESCA\|1\|185\|0.00541,STAD\|3\|395\|0.00759,STES\|3\|395\|0.00759
-	chr3	71008398	71008398	T	A	exonic	FOXP1	stoploss	LUAD\|1\|543\|0.00184
-	chr3	71015054	71015054	G	A	exonic	FOXP1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	71019936	71019936	T	C	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
rs550457312	chr3	71247446	71247446	G	A	exonic	FOXP1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
rs772047806	chr3	71179678	71179678	C	T	exonic	FOXP1	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr3	71015091	71015091	G	T	exonic	FOXP1	synonymous	ESCA\|1\|185\|0.00541
-	chr3	71027087	71027087	G	-	exonic	FOXP1	stopgain	ACC\|1\|90\|0.01111
-	chr3	71021800	71021800	G	A	exonic	FOXP1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	71050197	71050197	C	G	exonic	FOXP1	nonsynonymous	BLCA\|1\|396\|0.00253
rs759521321	chr3	71026106	71026106	C	T	exonic	FOXP1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	71021714	71021714	C	T	exonic	FOXP1	synonymous	SKCM\|1\|368\|0.00272
-	chr3	71021776	71021776	T	G	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	71090486	71090486	T	C	exonic	FOXP1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71096238	71096238	C	A	exonic	FOXP1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71026123	71026123	G	A	exonic	FOXP1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	71096126	71096126	G	A	exonic	FOXP1	stopgain	PRAD\|1\|499\|0.00200
-	chr3	71037200	71037200	G	A	exonic	FOXP1	nonsynonymous	CESC\|1\|194\|0.00515
-	chr3	71015207	71015207	C	A	exonic	FOXP1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	71247436	71247436	G	A	exonic	FOXP1	nonsynonymous	SKCM\|1\|368\|0.00272,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71015118	71015118	T	C	exonic	FOXP1	synonymous	LUAD\|1\|543\|0.00184
rs775699123	chr3	71247395	71247395	G	A	exonic	FOXP1	synonymous	SKCM\|1\|368\|0.00272
rs112773801	chr3	71008341	71008341	-	T	UTR3	FOXP1	unknown	ESCA\|2\|185\|0.01081,SARC\|1\|247\|0.00405
-	chr3	71026848	71026848	A	C	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	71355068	71355068	G	A	intronic	FOXP1	unknown	CESC\|1\|194\|0.00515
-	chr3	71096119	71096119	G	A	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	71179726	71179726	C	T	exonic	FOXP1	nonsynonymous	CESC\|1\|194\|0.00515
-	chr3	71101699	71101699	G	A	exonic	FOXP1	stopgain	BRCA\|1\|982\|0.00102
rs201155996	chr3	71247410	71247410	C	T	exonic	FOXP1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71008538	71008538	G	A	exonic	FOXP1	nonsynonymous	SKCM\|1\|368\|0.00272
rs797045585	chr3	71026112	71026112	G	C	exonic	FOXP1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr3	71027025	71027030	GGGTCC	-	exonic	FOXP1	nonframeshift	LUSC\|1\|178\|0.00562
rs868431423	chr3	71037196	71037196	C	T	exonic	FOXP1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	71101729	71101729	G	A	exonic	FOXP1	stopgain	BLCA\|1\|396\|0.00253
-	chr3	71026102	71026102	G	C	exonic	FOXP1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs146606219	chr3	71096114	71096114	G	C	exonic	FOXP1	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr3	71050186	71050186	C	T	exonic	FOXP1	synonymous	SKCM\|1\|368\|0.00272
-	chr3	71090529	71090529	T	-	exonic	FOXP1	frameshift	LUAD\|1\|543\|0.00184
-	chr3	71027138	71027138	C	T	exonic	FOXP1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	71096155	71096155	C	T	exonic	FOXP1	nonsynonymous	PCPG\|1\|184\|0.00543
rs138465768	chr3	71027139	71027139	C	T	exonic	FOXP1	synonymous	PRAD\|1\|499\|0.00200
-	chr3	71037150	71037150	G	A	exonic	FOXP1	stopgain	BLCA\|1\|396\|0.00253
-	chr3	71064720	71064720	T	A	exonic	FOXP1	nonsynonymous	LIHC\|1\|373\|0.00268
rs751543308	chr3	71026132	71026132	C	T	exonic	FOXP1	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr3	71247152	71247152	G	T	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	71096118	71096118	G	A	exonic	FOXP1	synonymous	SKCM\|1\|368\|0.00272
-	chr3	71021828	71021828	C	G	splicing	FOXP1	splicing	BLCA\|1\|396\|0.00253,LUAD\|1\|543\|0.00184
-	chr3	71090510	71090510	G	A	exonic	FOXP1	stopgain	LUSC\|1\|178\|0.00562
-	chr3	71021810	71021810	A	C	exonic	FOXP1	nonsynonymous	UCS\|1\|57\|0.01754
rs762082081	chr3	71247407	71247407	C	T	exonic	FOXP1	synonymous	SKCM\|1\|368\|0.00272
-	chr3	71037191	71037191	G	C	exonic	FOXP1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	71015079	71015079	C	T	exonic	FOXP1	synonymous	LUSC\|1\|178\|0.00562
-	chr3	71179761	71179761	-	A	exonic	FOXP1	frameshift	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr3	71008527	71008527	G	C	exonic	FOXP1	synonymous	UCEC\|1\|248\|0.00403
rs769331988	chr3	71019898	71019898	C	T	exonic	FOXP1	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr3	71247474	71247474	G	A	exonic	FOXP1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	71050168	71050168	G	T	exonic	FOXP1	synonymous	BLCA\|1\|396\|0.00253
-	chr3	71026835	71026835	C	T	exonic	FOXP1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs200629338	chr3	71027093	71027093	C	T	exonic	FOXP1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71008436	71008436	C	-	exonic	FOXP1	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71247394	71247394	C	A	exonic	FOXP1	nonsynonymous	HNSC\|1\|512\|0.00195
rs771680794	chr3	71096124	71096124	C	T	exonic	FOXP1	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr3	71096093	71096093	C	A	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	71027029	71027029	C	T	exonic	FOXP1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	71050155	71050155	G	A	exonic	FOXP1	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	71008343	71008345	TTT	-	UTR3	FOXP1	unknown	ESCA\|1\|185\|0.00541
rs768285337	chr3	71015109	71015109	G	A	exonic	FOXP1	synonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr3	71027060	71027060	C	A	exonic	FOXP1	nonsynonymous	LUAD\|2\|543\|0.00368
-	chr3	71015098	71015098	T	C	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	71247379	71247379	C	T	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
rs763413735	chr3	71026984	71026984	G	A	exonic	FOXP1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,SKCM\|4\|368\|0.01087
-	chr3	71179714	71179714	T	A	exonic	FOXP1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	71026850	71026850	A	T	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	71161786	71161786	T	C	exonic	FOXP1	synonymous	BRCA\|1\|982\|0.00102
-	chr3	71021808	71021808	A	C	exonic	FOXP1	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr3	71247201	71247201	G	T	exonic	FOXP1	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr3	71247175	71247175	C	T	exonic	FOXP1	stopgain	HNSC\|2\|512\|0.00391
-	chr3	71050204	71050204	G	C	exonic	FOXP1	synonymous	LUAD\|1\|543\|0.00184
-	chr3	71102787	71102787	C	A	exonic	FOXP1	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr3	71247358	71247359	GC	-	exonic	FOXP1	frameshift	PAAD\|12\|185\|0.06486
-	chr3	71096156	71096156	G	A	exonic	FOXP1	nonsynonymous	SARC\|1\|247\|0.00405
-	chr3	71247109	71247109	A	C	exonic	FOXP1	synonymous	ESCA\|1\|185\|0.00541
rs372403441	chr3	71026839	71026839	G	A	exonic	FOXP1	synonymous	PAAD\|1\|185\|0.00541
-	chr3	71008510	71008510	T	C	exonic	FOXP1	nonsynonymous	UCS\|1\|57\|0.01754
-	chr3	71050125	71050125	-	AGCTC	exonic	FOXP1	frameshift	PRAD\|1\|499\|0.00200
-	chr3	71027015	71027015	G	A	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	71026811	71026811	C	T	exonic	FOXP1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr3	71247427	71247427	G	A	exonic	FOXP1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	71161711	71161711	C	T	exonic	FOXP1	synonymous	SKCM\|2\|368\|0.00543
-	chr3	71021728	71021728	G	A	exonic	FOXP1	stopgain	UCEC\|1\|248\|0.00403
-	chr3	71050158	71050158	C	A	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
rs869025203	chr3	71021818	71021818	G	A	exonic	FOXP1	nonsynonymous	BLCA\|1\|396\|0.00253,BRCA\|1\|982\|0.00102,COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	71015100	71015100	C	A	exonic	FOXP1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71161757	71161757	T	C	exonic	FOXP1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	71102859	71102859	G	T	exonic	FOXP1	synonymous	BLCA\|1\|396\|0.00253
rs866381610	chr3	71008430	71008430	C	T	exonic	FOXP1	nonsynonymous	SKCM\|1\|368\|0.00272,UCEC\|1\|248\|0.00403
-	chr3	71027051	71027051	T	-	exonic	FOXP1	frameshift	PRAD\|1\|499\|0.00200
-	chr3	71008410	71008410	C	A	exonic	FOXP1	nonsynonymous	LUAD\|1\|543\|0.00184
rs777378675	chr3	71247374	71247374	G	A	exonic	FOXP1	synonymous	HNSC\|1\|512\|0.00195
-	chr3	71096092	71096092	C	T	splicing	FOXP1	splicing	BLCA\|1\|396\|0.00253
rs760260048	chr3	71015130	71015130	G	A	exonic	FOXP1	synonymous	UCEC\|1\|248\|0.00403
-	chr3	71102876	71102876	G	A	exonic	FOXP1	stopgain	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr3	71019957	71019957	C	T	splicing	FOXP1	splicing	HNSC\|1\|512\|0.00195
rs541340602	chr3	71008511	71008511	C	T	exonic	FOXP1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	71247404	71247404	G	A	exonic	FOXP1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71015120	71015120	C	T	exonic	FOXP1	nonsynonymous	CESC\|1\|194\|0.00515
-	chr3	71015081	71015081	C	T	exonic	FOXP1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71015121	71015121	C	A	exonic	FOXP1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	71050152	71050152	T	A	exonic	FOXP1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	71247211	71247211	G	C	exonic	FOXP1	synonymous	BRCA\|2\|982\|0.00204
rs143503790	chr3	71026983	71026983	C	T	exonic	FOXP1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,UCEC\|1\|248\|0.00403
-	chr3	71179760	71179760	G	T	exonic	FOXP1	stopgain	CHOL\|1\|35\|0.02857
-	chr3	71037144	71037144	C	T	splicing	FOXP1	splicing	OV\|1\|469\|0.00213
-	chr3	71026978	71026978	C	A	splicing	FOXP1	splicing	BRCA\|1\|982\|0.00102
-	chr3	71179740	71179740	G	T	exonic	FOXP1	stopgain	BLCA\|1\|396\|0.00253
-	chr3	71008342	71008342	T	-	UTR3	FOXP1	unknown	ESCA\|1\|185\|0.00541,STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr3	71247393	71247393	C	T	exonic	FOXP1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	71026099	71026099	G	A	exonic	FOXP1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71096185	71096185	A	T	exonic	FOXP1	stopgain	BRCA\|1\|982\|0.00102
-	chr3	71021723	71021723	C	A	exonic	FOXP1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	71247353	71247353	C	T	exonic	FOXP1	synonymous	SKCM\|1\|368\|0.00272
-	chr3	71026154	71026154	C	A	exonic	FOXP1	stopgain	UCEC\|1\|248\|0.00403
-	chr3	71008498	71008498	G	T	exonic	FOXP1	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr3	71096127	71096127	C	A	exonic	FOXP1	synonymous	PRAD\|1\|499\|0.00200
-	chr3	71090609	71090609	T	C	exonic	FOXP1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71101701	71101701	T	-	exonic	FOXP1	frameshift	COADREAD\|2\|489\|0.00409,READ\|2\|122\|0.01639
rs769711833	chr3	71090577	71090577	T	A	exonic	FOXP1	synonymous	CESC\|1\|194\|0.00515
-	chr3	71090537	71090537	T	G	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
rs772162873	chr3	71008431	71008431	G	A	exonic	FOXP1	synonymous	PAAD\|1\|185\|0.00541
-	chr3	71021749	71021749	C	T	exonic	FOXP1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71096104	71096104	G	A	exonic	FOXP1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr3	71161692	71161692	G	A	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	71008538	71008538	G	T	exonic	FOXP1	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr3	71096168	71096168	G	T	exonic	FOXP1	nonsynonymous	PAAD\|1\|185\|0.00541
rs797045586	chr3	71021817	71021817	C	T	exonic	FOXP1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	71247445	71247445	C	A	exonic	FOXP1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	71064794	71064794	C	T	exonic	FOXP1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	71027107	71027107	G	A	exonic	FOXP1	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr3	71021784	71021784	C	T	exonic	FOXP1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	71247488	71247488	G	T	exonic	FOXP1	synonymous	SKCM\|1\|368\|0.00272
-	chr3	71064696	71064698	TTA	-	splicing	FOXP1	unknown	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	71026822	71026822	G	T	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
rs766683691	chr3	71026863	71026863	C	T	exonic	FOXP1	synonymous	LIHC\|1\|373\|0.00268
-	chr3	71027069	71027069	C	A	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	71064750	71064750	G	A	exonic	FOXP1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,ESCA\|1\|185\|0.00541
-	chr3	71026794	71026794	C	G	exonic	FOXP1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	71021296	71021296	G	T	exonic	FOXP1	stopgain	CESC\|1\|194\|0.00515,UCEC\|1\|248\|0.00403
-	chr3	71021322	71021322	G	A	exonic	FOXP1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	71037204	71037204	G	A	exonic	FOXP1	stopgain	PRAD\|1\|499\|0.00200
-	chr3	71247495	71247495	C	T	exonic	FOXP1	nonsynonymous	SKCM\|1\|368\|0.00272
rs797045584	chr3	71026115	71026115	G	A	exonic	FOXP1	stopgain	BLCA\|1\|396\|0.00253
-	chr3	71101768	71101768	G	A	exonic	FOXP1	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204

Disease information of FOXP1

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TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
FOXP1	Burkitt Lymphoma	C02;C04;C15;C20	Neoplastic Process	ORPHANET
FOXP1	Lymphatic Metastasis	C04;C23	Neoplastic Process	CTD_human
FOXP1	Neoplasm Invasiveness	C04;C23	Pathologic Function	CTD_human
FOXP1	Pancreatic Neoplasm	C04;C06;C19	Neoplastic Process	CTD_human
FOXP1	Vitiligo	C17	Disease or Syndrome	CTD_human
FOXP1	Juvenile-Onset Still Disease	C05;C17;C20	Disease or Syndrome	CTD_human
FOXP1	Mucosa-Associated Lymphoid Tissue Lymphoma	C04;C15;C20	Neoplastic Process	ORPHANET
FOXP1	Adenocarcinoma Of Esophagus	C04;C06	Neoplastic Process	CTD_human
FOXP1	Malignant neoplasm of pancreas	C04;C06;C19	Neoplastic Process	CTD_human
FOXP1	Precursor B-cell lymphoblastic leukemia		Neoplastic Process	ORPHANET
FOXP1	Autism Spectrum Disorders	F03	Mental or Behavioral Dysfunction	CTD_human
FOXP1	Neurodevelopmental Disorders	F03	Mental or Behavioral Dysfunction	CTD_human
FOXP1	Juvenile arthritis	C05;C17;C20	Disease or Syndrome	CTD_human
FOXP1	Intellectual Disability	C10;C23;F01;F03	Mental or Behavioral Dysfunction	GENOMICS_ENGLAND
FOXP1	Juvenile psoriatic arthritis	C05;C17;C20	Disease or Syndrome	CTD_human
FOXP1	MENTAL RETARDATION WITH LANGUAGE IMPAIRMENT AND WITH OR WITHOUT AUTISTIC FEATURES		Disease or Syndrome	CTD_human;ORPHANET;UNIPROT

Pathway associated with FOXP1

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pathway_ID	pathway_name	pathway_source	gene_number	edge_number

Go term information of FOXP1

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GO_term_name	GO_term_type	TF_name
GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION	BP	FOXP1
GO_MYELOID_CELL_DEVELOPMENT	BP	FOXP1
GO_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS	BP	FOXP1
GO_SECRETION_BY_CELL	BP	FOXP1
GO_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	BP	FOXP1
GO_ALPHA_BETA_T_CELL_DIFFERENTIATION	BP	FOXP1
GO_BONE_CELL_DEVELOPMENT	BP	FOXP1
GO_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY	BP	FOXP1
GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS	BP	FOXP1
GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION	BP	FOXP1
GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	BP	FOXP1
GO_REGULATION_OF_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY	BP	FOXP1
GO_BONE_DEVELOPMENT	BP	FOXP1
GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY	BP	FOXP1
GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION	BP	FOXP1
GO_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION	BP	FOXP1
GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	BP	FOXP1
GO_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE	BP	FOXP1
GO_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION	BP	FOXP1
GO_REGULATION_OF_INTERLEUKIN_1_PRODUCTION	BP	FOXP1
GO_MACROPHAGE_ACTIVATION	BP	FOXP1
GO_NEGATIVE_REGULATION_OF_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY	BP	FOXP1
GO_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS	BP	FOXP1
GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS	BP	FOXP1
GO_CYTOKINE_SECRETION	BP	FOXP1
GO_ALPHA_BETA_T_CELL_ACTIVATION	BP	FOXP1
GO_REGULATION_OF_MONOCYTE_DIFFERENTIATION	BP	FOXP1
GO_REGULATION_OF_INTERLEUKIN_1_SECRETION	BP	FOXP1
GO_OSTEOCLAST_DIFFERENTIATION	BP	FOXP1
GO_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	BP	FOXP1
GO_T_CELL_DIFFERENTIATION	BP	FOXP1
GO_REGULATION_OF_DEFENSE_RESPONSE_TO_BACTERIUM	BP	FOXP1
GO_NEGATIVE_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS	BP	FOXP1
GO_REGULATION_OF_INTERLEUKIN_12_PRODUCTION	BP	FOXP1
GO_PROTEIN_SELF_ASSOCIATION	MF	FOXP1
GO_ANDROGEN_RECEPTOR_BINDING	MF	FOXP1
GO_STEROID_HORMONE_RECEPTOR_BINDING	MF	FOXP1

Survival analysis of FOXP1

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of FOXP1

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)