Sample overview of Caco-2

Sample ID: Sample_02_322
Biosample type: Cell line
Tissue type: Colon
Biosample name: Caco-2
Data source: NCBI GEO/SRA
GSE ID: GSE96069
Cancer type: colon cancer cells
CRC number: 743
TF number of all CRCs: 40
TF list of all CRCs: HNF4A, KLF5, ELF3, SREBF2, FOXP1, SMAD3, BCL6, CDX2, TEAD1, ZBTB7B, TEAD3, JUNB, ELF1, TGIF1, FOXQ1, CEBPB, FOXA1, HES1, DBP, MAFF, FOXA2, SP3, SREBF1, PBX1, IRF8, CREB3L2, NFAT5, NR2F2, FOSL2, MSX2, NR2F6, ARID5B, GATA6, NFE2L2, IRF2, HNF1A, CEBPA, CEBPG, NFATC2, ZBED1

The most representative CRC of Caco-2
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Relationship plot of CRC model
TF number of this CRC: 14
CRC socre: 455.5
TF list of the most representative CRC
TF name TF family Frequency of TFs
BCL6 ZBTB 447 / 743
DBP TF_bZIP 230 / 743
ELF1 ETS 301 / 743
ELF3 ETS 730 / 743
FOXP1 Fork_head 511 / 743
HNF4A RXR-like 743 / 743
JUNB TF_bZIP 310 / 743
KLF5 zf-C2H2 742 / 743
MAFF TF_bZIP 229 / 743
SMAD3 MH1 470 / 743
SREBF2 bHLH 626 / 743
TEAD1 TEA 368 / 743
TEAD3 TEA 316 / 743
ZBTB7B ZBTB 354 / 743

All CRCs of Caco-2
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
HNF4A 743 / 743 RXR-like ENSG00000101076
KLF5 742 / 743 zf-C2H2 ENSG00000102554
ELF3 730 / 743 ETS ENSG00000163435
SREBF2 626 / 743 bHLH ENSG00000198911
FOXP1 511 / 743 Fork_head ENSG00000114861
SMAD3 470 / 743 MH1 ENSG00000166949
BCL6 447 / 743 ZBTB ENSG00000113916
CDX2 437 / 743 Homeobox ENSG00000165556
TEAD1 368 / 743 TEA ENSG00000187079
ZBTB7B 354 / 743 ZBTB ENSG00000160685
TEAD3 316 / 743 TEA ENSG00000007866
JUNB 310 / 743 TF_bZIP ENSG00000171223
ELF1 301 / 743 ETS ENSG00000120690
TGIF1 287 / 743 Homeobox ENSG00000177426
FOXQ1 274 / 743 Fork_head ENSG00000164379
CEBPB 271 / 743 TF_bZIP ENSG00000172216
FOXA1 234 / 743 Fork_head ENSG00000129514
HES1 232 / 743 bHLH ENSG00000114315
DBP 230 / 743 TF_bZIP ENSG00000105516
MAFF 229 / 743 TF_bZIP ENSG00000185022
FOXA2 227 / 743 Fork_head ENSG00000125798
SP3 219 / 743 zf-C2H2 ENSG00000172845
SREBF1 212 / 743 bHLH ENSG00000072310
PBX1 211 / 743 Homeobox ENSG00000185630
IRF8 200 / 743 IRF ENSG00000140968
CREB3L2 181 / 743 TF_bZIP ENSG00000182158
NFAT5 167 / 743 RHD ENSG00000102908
NR2F2 152 / 743 RXR-like ENSG00000185551
FOSL2 135 / 743 TF_bZIP ENSG00000075426
MSX2 124 / 743 Homeobox ENSG00000120149
NR2F6 121 / 743 RXR-like ENSG00000160113
ARID5B 100 / 743 ARID ENSG00000150347
GATA6 62 / 743 zf-GATA ENSG00000141448
NFE2L2 60 / 743 TF_bZIP ENSG00000116044
IRF2 52 / 743 IRF ENSG00000168310
HNF1A 51 / 743 Homeobox ENSG00000135100
CEBPA 41 / 743 TF_bZIP ENSG00000245848
CEBPG 40 / 743 TF_bZIP ENSG00000153879
NFATC2 12 / 743 RHD ENSG00000101096
ZBED1 1 / 743 zf-BED ENSG00000214717

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
CDX2 48 65 113
NFATC2 21 61 82
FOXP1 48 71 119
ARID5B 50 46 96
ZBED1 35 16 51
SMAD3 45 71 116
TEAD3 40 68 108
TEAD1 46 68 114
NR2F2 37 64 101
ELF3 48 70 118
MAFF 48 58 106
FOXA1 46 69 115
CEBPA 47 44 91
CEBPG 42 35 77
GATA6 47 48 95
NFE2L2 32 64 96
ZBTB7B 48 63 111
KLF5 49 72 121
HNF1A 35 70 105
FOSL2 41 54 95
MSX2 41 60 101
FOXQ1 48 59 107
CEBPB 47 53 100
JUNB 45 58 103
IRF2 30 69 99
SP3 38 69 107
ELF1 42 69 111
HES1 44 54 98
NR2F6 38 69 107
PBX1 46 64 110
NFAT5 42 66 108
FOXA2 46 70 116
SREBF2 43 69 112
IRF8 36 70 106
HNF4A 50 73 123
CREB3L2 46 56 102
SREBF1 43 68 111
DBP 40 65 105
BCL6 43 71 114
TGIF1 44 63 107

Expression of TFs in all CRCs