TF information

TF name: NFAT5
TF family: RHD
Ensembl gene ID: ENSG00000102908
Ensembl protein ID: ENSP00000455628, ENSP00000346420, ENSP00000457593, ENSP00000486610, ENSP00000338806, ENSP00000377343, ENSP00000462061
Entrez gene ID: 10725
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of NFAT5 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_316Cell lineNeuroblastomaCHP2120.032967032967033
Sample_02_322Cell lineColonCaco-20.22476446837147

NFAT5 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name

NFAT5 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with NFAT5
Download

Mutation of NFAT5
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of NFAT5

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr166972695869726958-TexonicNFAT5frameshift LUSC|1|178|0.00562
-chr166972487069724870AGexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166960244069602440GAexonicNFAT5nonsynonymous OV|1|469|0.00213
-chr166968729169687291CGexonicNFAT5stopgain KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr166971881169718811TCexonicNFAT5nonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr166968966969689669TCexonicNFAT5nonsynonymous LIHC|1|373|0.00268
-chr166972637869726378GAexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166972768469727684AGexonicNFAT5nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166970394869703948GAexonicNFAT5nonsynonymous HNSC|1|512|0.00195
-chr166972785169727851CGexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166972586269725862GTexonicNFAT5nonsynonymous BRCA|1|982|0.00102
-chr166972710369727103CAexonicNFAT5synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166968128969681289GCexonicNFAT5nonsynonymous PAAD|1|185|0.00541
-chr166972714069727140CTexonicNFAT5stopgain THCA|1|504|0.00198
rs768835823chr166972709969727099CTexonicNFAT5nonsynonymous ESCA|1|185|0.00541
rs531151605chr166972588569725885CTexonicNFAT5synonymous UCEC|1|248|0.00403
-chr166972573369725733TAexonicNFAT5nonsynonymous SKCM|1|368|0.00272
-chr166968148269681482GAexonicNFAT5nonsynonymous SARC|1|247|0.00405
-chr166972668269726682CTexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166970414869704148CGexonicNFAT5nonsynonymous BRCA|1|982|0.00102
-chr166972784769727847TCexonicNFAT5synonymous PRAD|1|499|0.00200
-chr166972613769726137CTexonicNFAT5synonymous UCEC|1|248|0.00403
-chr166972615969726159G-exonicNFAT5frameshift LIHC|1|373|0.00268
-chr166969367469693674AGexonicNFAT5nonsynonymous UCEC|1|248|0.00403
-chr166971110969711109CTexonicNFAT5nonsynonymous HNSC|1|512|0.00195
-chr166972644969726449GAexonicNFAT5synonymous UCEC|1|248|0.00403
-chr166972649869726498CGexonicNFAT5nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
rs762586717chr166972727469727274GAexonicNFAT5synonymous UCEC|1|248|0.00403
rs369860927chr166972583369725833CTexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166968096669680966GTexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166972921769729217GTexonicNFAT5nonsynonymous UCEC|1|248|0.00403
-chr166972611469726114CGexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166968139869681398-TexonicNFAT5frameshift UCEC|1|248|0.00403
-chr166972725969727259-TexonicNFAT5frameshift KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr166968123669681236GCexonicNFAT5nonsynonymous CESC|1|194|0.00515
-chr166972494269724942TCexonicNFAT5nonsynonymous KICH|1|66|0.01515,KIPAN|1|799|0.00125
-chr166972592969725929CTexonicNFAT5nonsynonymous PAAD|1|185|0.00541
-chr166972916069729160AGexonicNFAT5synonymous THCA|1|504|0.00198
-chr166972648869726488GAexonicNFAT5synonymous BLCA|1|396|0.00253
-chr166972496069724960CAexonicNFAT5nonsynonymous UCS|1|57|0.01754
rs751126952chr166969367269693672CTexonicNFAT5synonymous SKCM|1|368|0.00272
-chr166970397769703977GAexonicNFAT5synonymous BRCA|2|982|0.00204,LUAD|1|543|0.00184
-chr166972695869726958ATexonicNFAT5nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166972781469727814GAexonicNFAT5synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166968117269681172ACexonicNFAT5synonymous BRCA|1|982|0.00102
-chr166972792469727924TCexonicNFAT5nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr166969366569693665CGexonicNFAT5nonsynonymous OV|1|469|0.00213
-chr166970392669703926CAexonicNFAT5nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr166972614169726141AGexonicNFAT5nonsynonymous UCEC|1|248|0.00403
-chr166972751569727515T-exonicNFAT5frameshift HNSC|1|512|0.00195
-chr166970397569703975CGexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166972489869724898GAexonicNFAT5synonymous LUAD|1|543|0.00184
rs202102702chr166972606069726060AGexonicNFAT5nonsynonymous HNSC|1|512|0.00195
-chr166972799769727997GAexonicNFAT5nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr166972652069726520-AexonicNFAT5frameshift BRCA|1|982|0.00102
-chr166972573469725734CAexonicNFAT5stopgain SKCM|1|368|0.00272
-chr166970396869703968GTexonicNFAT5nonsynonymous ESCA|1|185|0.00541,UCEC|1|248|0.00403
-chr166968133169681331AGexonicNFAT5synonymous LUAD|1|543|0.00184
-chr166972578969725789ATexonicNFAT5synonymous BRCA|1|982|0.00102
-chr166968102569681025CTexonicNFAT5synonymous HNSC|1|512|0.00195
-chr166972906669729066CAexonicNFAT5nonsynonymous ESCA|1|185|0.00541
-chr166972642169726422AG-exonicNFAT5frameshift PAAD|28|185|0.15135,SARC|1|247|0.00405,SKCM|1|368|0.00272,STAD|3|395|0.00759,STES|3|395|0.00759,UCEC|1|248|0.00403
-chr166972743969727439ACexonicNFAT5synonymous BRCA|1|982|0.00102
-chr166966033169660331GTexonicNFAT5nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166972714069727140CAexonicNFAT5nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
rs767801967chr166972661669726616AGexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166972698269726982CGexonicNFAT5stopgain HNSC|1|512|0.00195
-chr166972593769725937ATexonicNFAT5stopgain LUAD|1|543|0.00184
-chr166972577169725771GAexonicNFAT5synonymous HNSC|1|512|0.00195
-chr166972491669724916ATexonicNFAT5synonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
rs760113102chr166972775469727754CTexonicNFAT5synonymous LIHC|1|373|0.00268
-chr166972632969726329ACexonicNFAT5synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166972633069726330GCexonicNFAT5nonsynonymous BRCA|1|982|0.00102
-chr166968119169681191A-exonicNFAT5frameshift BLCA|1|396|0.00253
-chr166971885169718851CTexonicNFAT5synonymous SKCM|1|368|0.00272
-chr166971886669718866CTexonicNFAT5synonymous LUAD|1|543|0.00184
-chr166968963769689637ATexonicNFAT5nonsynonymous SKCM|1|368|0.00272
-chr166968965469689654CTexonicNFAT5nonsynonymous PAAD|1|185|0.00541
-chr166972589569725908TTGCAGCAGGCTAC-exonicNFAT5frameshift BLCA|1|396|0.00253
-chr166968970369689703GAsplicingNFAT5splicing COAD|1|367|0.00272,COADREAD|1|489|0.00204,GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr166972712569727125CGexonicNFAT5nonsynonymous HNSC|1|512|0.00195
-chr166972493169724931GCexonicNFAT5nonsynonymous UCEC|1|248|0.00403
-chr166972754769727547AGexonicNFAT5synonymous PAAD|1|185|0.00541
-chr166972758669727586TGexonicNFAT5nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr166972710569727105CTexonicNFAT5nonsynonymous HNSC|1|512|0.00195
-chr166971121969711219CTexonicNFAT5synonymous HNSC|1|512|0.00195
-chr166972783269727832CTexonicNFAT5synonymous SKCM|1|368|0.00272
-chr166972620269726202AGexonicNFAT5nonsynonymous PRAD|1|499|0.00200
-chr166972768369727683CGexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166966038469660384CTexonicNFAT5nonsynonymous UCEC|1|248|0.00403
-chr166972920369729203CAexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166972791569727915CTexonicNFAT5nonsynonymous CESC|1|194|0.00515
-chr166972700769727007ACexonicNFAT5nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166972726769727267CTexonicNFAT5nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr166968963569689635GCexonicNFAT5nonsynonymous HNSC|1|512|0.00195
-chr166968963169689631CAexonicNFAT5stopgain HNSC|1|512|0.00195
-chr166968137269681372GAexonicNFAT5nonsynonymous CESC|1|194|0.00515,UCEC|1|248|0.00403
-chr166972779169727791CTexonicNFAT5stopgain LUSC|1|178|0.00562
-chr166972655369726553GTexonicNFAT5nonsynonymous SARC|1|247|0.00405
-chr166969371369693713CTexonicNFAT5nonsynonymous UCEC|1|248|0.00403
-chr166972739269727392CTexonicNFAT5nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166972707069727070ACexonicNFAT5synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166972618869726188ACexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166972904369729043TCexonicNFAT5synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166972726069727260T-exonicNFAT5frameshift LIHC|1|373|0.00268
-chr166972591069725910CTexonicNFAT5stopgain PAAD|1|185|0.00541
rs369476982chr166972665769726657CTexonicNFAT5nonsynonymous SKCM|1|368|0.00272,UCS|1|57|0.01754
-chr166968715269687152CGexonicNFAT5nonsynonymous BRCA|1|982|0.00102
-chr166972639769726397CGexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166972673869726738ACexonicNFAT5nonsynonymous UCEC|1|248|0.00403
-chr166968716769687167GAexonicNFAT5nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166972658969726589CTexonicNFAT5nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr166972493769724937ACexonicNFAT5nonsynonymous LIHC|1|373|0.00268
rs745802873chr166972743769727437CTexonicNFAT5nonsynonymous SKCM|1|368|0.00272
-chr166968139869681398GTexonicNFAT5nonsynonymous ESCA|1|185|0.00541
-chr166972921269729212GAexonicNFAT5nonsynonymous UCEC|1|248|0.00403
-chr166972788069727880TGexonicNFAT5nonsynonymous SKCM|1|368|0.00272
-chr166970394269703943GA-exonicNFAT5frameshift LIHC|1|373|0.00268
-chr166972723369727233CTexonicNFAT5stopgain SKCM|2|368|0.00543
-chr166972581469725814AGexonicNFAT5nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166970390569703905CGexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166969374469693744CGexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166972732869727328CGexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166972630769726307GTexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166966035269660352TCexonicNFAT5synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr166968127369681273CTexonicNFAT5nonsynonymous SKCM|1|368|0.00272
-chr166972791069727910ATexonicNFAT5nonsynonymous THCA|1|504|0.00198
-chr166972755769727557CTexonicNFAT5stopgain STAD|1|395|0.00253,STES|1|395|0.00253
rs751187444chr166972588469725884GAexonicNFAT5nonsynonymous OV|1|469|0.00213
-chr166971116269711162GAexonicNFAT5synonymous LUAD|1|543|0.00184
-chr166970416169704161ATexonicNFAT5nonsynonymous LUSC|1|178|0.00562
-chr166972659669726596GCexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166973834869738348ATUTR3NFAT5unknown ESCA|1|185|0.00541
-chr166972741069727410CAexonicNFAT5nonsynonymous THCA|1|504|0.00198
-chr166971879269718792GTsplicingNFAT5splicing BRCA|1|982|0.00102
-chr166972484769724847GAexonicNFAT5nonsynonymous CESC|1|194|0.00515
-chr166972636069726360TGexonicNFAT5nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr166968141069681410GAexonicNFAT5nonsynonymous UCEC|1|248|0.00403
-chr166972621369726213GAexonicNFAT5nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
rs764512084chr166972641269726412CGexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166972635469726354GCexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166973736269737362GTUTR3NFAT5unknown ESCA|1|185|0.00541
-chr166972746669727466ACexonicNFAT5nonsynonymous UCEC|1|248|0.00403
-chr166972795069727950CTexonicNFAT5stopgain SKCM|1|368|0.00272
-chr166972686369726863A-exonicNFAT5frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr166968137469681374CTexonicNFAT5stopgain STAD|1|395|0.00253,STES|1|395|0.00253
-chr166972570969725709GAexonicNFAT5nonsynonymous OV|1|469|0.00213
-chr166972775469727754CGexonicNFAT5synonymous CESC|1|194|0.00515
-chr166972642269726422GAexonicNFAT5synonymous BLCA|1|396|0.00253,ESCA|2|185|0.01081,THCA|1|504|0.00198,UCEC|1|248|0.00403
rs201390290chr166966038869660388CTexonicNFAT5synonymous LUAD|6|543|0.01105
-chr166968110669681106CTexonicNFAT5synonymous SKCM|1|368|0.00272
-chr166968963569689635GTexonicNFAT5stopgain UCEC|1|248|0.00403
-chr166972695769726957ACexonicNFAT5nonsynonymous UCEC|1|248|0.00403
-chr166972700569727005CGexonicNFAT5nonsynonymous HNSC|1|512|0.00195
-chr166968116869681168CTexonicNFAT5nonsynonymous SKCM|1|368|0.00272
-chr166968730869687308CTexonicNFAT5stopgain BLCA|1|396|0.00253
-chr166972579569725795CGexonicNFAT5nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr166971885269718852TCexonicNFAT5nonsynonymous LIHC|1|373|0.00268
-chr166972602469726024GAexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166972788469727884CTexonicNFAT5stopgain CESC|1|194|0.00515
-chr166968127469681274CTexonicNFAT5synonymous SKCM|1|368|0.00272
-chr166972697769726985TCATTCACA-exonicNFAT5nonframeshift HNSC|1|512|0.00195
-chr166968146569681465ATexonicNFAT5nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr166968144669681446CGexonicNFAT5nonsynonymous BLCA|1|396|0.00253
-chr166968117569681175TCexonicNFAT5synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr166972599169725991GAexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166972630869726308CTexonicNFAT5synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr166972710869727108CGexonicNFAT5nonsynonymous HNSC|1|512|0.00195
-chr166969376169693761CGexonicNFAT5nonsynonymous LUAD|1|543|0.00184
-chr166972747969727479CTexonicNFAT5stopgain SKCM|1|368|0.00272
-chr166972910869729124GCCAACCACAAAACGAG-exonicNFAT5frameshift SARC|1|247|0.00405
-chr166968106369681063CTexonicNFAT5nonsynonymous BRCA|1|982|0.00102
-chr166969376569693765TCexonicNFAT5synonymous BRCA|1|982|0.00102

Disease information of NFAT5
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source

Pathway associated with NFAT5
pathway_ID pathway_name pathway_source gene_number edge_number

Go term information of NFAT5
GO_term_name GO_term_type TF_name
GO_EXCRETION BP NFAT5
GO_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING BP NFAT5
GO_CYTOKINE_PRODUCTION BP NFAT5
GO_REGULATION_OF_CALCINEURIN_NFAT_SIGNALING_CASCADE BP NFAT5

Survival analysis of NFAT5



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of NFAT5