Cancer CRCdb

TF information

TF name:	BCL6
TF family:	ZBTB
Ensembl gene ID:	ENSG00000113916
Ensembl protein ID:	ENSP00000413122, ENSP00000413122, ENSP00000479784, ENSP00000479784, ENSP00000232014, ENSP00000232014, ENSP00000384371, ENSP00000384371
Entrez gene ID:	604

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of BCL6 in all biosamples

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Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_01_022	Cell line	Prostate	C4-2B	0.57142857142857
Sample_02_007	Other	Cervical	cervical-cancer_vector	0.50993377483444
Sample_02_078	Primary cell	Neuroblastoma	low-MYCN-Neuroblastoma-patient-cells	1
Sample_02_095	Cell line	Mammary Gland	MDA-MB-468	0.27509727626459
Sample_02_164	Cell line	Lung	H2087_Parental	0.83333333333333
Sample_02_205	Tissue	Stomach	Gastric_Primary_Sample_T	0.24444444444444
Sample_02_228	Cell line	Oesophagus	KYSE510	0.94874184529357
Sample_02_322	Cell line	Colon	Caco-2	0.60161507402423
Sample_02_323	Cell line	Colon	RKO	0.55
Sample_02_394	Cell line	Mammary Gland	T-47D_2	1
Sample_02_395	Cell line	Mammary Gland	BT-549	0.38937062937063
Sample_02_403	Cell line	Mammary Gland	T-47D_untreat	0.69318181818182
Sample_02_413	Tissue	Brain	GBM_2493	0.18681318681319

BCL6 distribution in samples’ most representative CRC

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Sample ID	Tissue type	Biosample type	Biosample name
Sample_01_022	Prostate	Cell line	C4-2B
Sample_02_078	Neuroblastoma	Primary cell	low-MYCN-Neuroblastoma-patient-cells
Sample_02_164	Lung	Cell line	H2087_Parental
Sample_02_228	Oesophagus	Cell line	KYSE510
Sample_02_322	Colon	Cell line	Caco-2
Sample_02_323	Colon	Cell line	RKO
Sample_02_394	Mammary Gland	Cell line	T-47D_2
Sample_02_403	Mammary Gland	Cell line	T-47D_untreat

BCL6 distribution in all CRCs

Genomic distribution of SEs associated with BCL6

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Mutation of BCL6

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Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of BCL6

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr3	187451445	187451445	G	C	exonic	BCL6	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr3	187447752	187447752	C	G	exonic	BCL6	synonymous	LUAD\|2\|543\|0.00368
-	chr3	187447753	187447753	C	G	exonic	BCL6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	187443293	187443293	A	-	exonic	BCL6	frameshift	CESC\|1\|194\|0.00515
-	chr3	187449586	187449586	C	T	exonic	BCL6	synonymous	SKCM\|1\|368\|0.00272
rs770320988	chr3	187446269	187446269	-	G	exonic	BCL6	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187447260	187447260	C	A	exonic	BCL6	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	187442765	187442765	G	A	exonic	BCL6	synonymous	SKCM\|1\|368\|0.00272
rs780615769	chr3	187446846	187446846	G	A	exonic	BCL6	synonymous	BLCA\|1\|396\|0.00253,UCEC\|1\|248\|0.00403
rs143522266	chr3	187446312	187446312	C	T	exonic	BCL6	nonsynonymous	UCEC\|2\|248\|0.00806
-	chr3	187449569	187449569	G	A	exonic	BCL6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	187447645	187447645	C	T	exonic	BCL6	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr3	187447676	187447676	G	A	exonic	BCL6	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs370060611	chr3	187446200	187446200	C	T	exonic	BCL6	synonymous	LIHC\|1\|373\|0.00268
-	chr3	187442764	187442764	G	A	exonic	BCL6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	187444628	187444628	G	A	exonic	BCL6	synonymous	SKCM\|1\|368\|0.00272
-	chr3	187444607	187444607	G	T	exonic	BCL6	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187447612	187447612	G	C	exonic	BCL6	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	187451419	187451419	G	C	exonic	BCL6	nonsynonymous	BRCA\|1\|982\|0.00102
rs776120197	chr3	187447327	187447327	C	T	exonic	BCL6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187443325	187443325	G	A	exonic	BCL6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	187444625	187444625	C	T	exonic	BCL6	synonymous	BLCA\|1\|396\|0.00253
rs760006045	chr3	187449662	187449662	T	C	exonic	BCL6	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr3	187443418	187443418	C	T	splicing	BCL6	splicing	UCEC\|1\|248\|0.00403
-	chr3	187447665	187447665	C	A	exonic	BCL6	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	187447462	187447462	C	A	exonic	BCL6	nonsynonymous	LUSC\|1\|178\|0.00562
rs755666072	chr3	187443403	187443403	G	A	exonic	BCL6	nonsynonymous	SARC\|1\|247\|0.00405
-	chr3	187447044	187447044	G	A	exonic	BCL6	synonymous	HNSC\|1\|512\|0.00195
-	chr3	187446278	187446278	C	A	exonic	BCL6	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr3	187447117	187447117	G	A	exonic	BCL6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	187440334	187440334	C	T	exonic	BCL6	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	187447315	187447315	T	A	exonic	BCL6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,OV\|1\|469\|0.00213
-	chr3	187444586	187444586	C	A	exonic	BCL6	nonsynonymous	LUAD\|1\|543\|0.00184
rs142220629	chr3	187447543	187447543	C	T	exonic	BCL6	nonsynonymous	LUAD\|1\|543\|0.00184,PRAD\|2\|499\|0.00401
rs535108808	chr3	187446261	187446261	G	A	exonic	BCL6	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr3	187463074	187463074	-	A	intronic	BCL6	unknown	ESCA\|1\|185\|0.00541
-	chr3	187447411	187447411	G	C	exonic	BCL6	nonsynonymous	HNSC\|1\|512\|0.00195
rs370653196	chr3	187447620	187447620	C	T	exonic	BCL6	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs748221363	chr3	187449604	187449604	T	G	exonic	BCL6	synonymous	UCEC\|1\|248\|0.00403
rs750212558	chr3	187440292	187440292	C	T	exonic	BCL6	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122,LUAD\|1\|543\|0.00184
-	chr3	187447774	187447774	C	T	exonic	BCL6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr3	187446943	187446943	G	A	exonic	BCL6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	187446270	187446270	G	-	exonic	BCL6	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187447264	187447264	T	C	exonic	BCL6	nonsynonymous	UCEC\|1\|248\|0.00403
rs137878288	chr3	187446313	187446313	G	A	exonic	BCL6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	187446173	187446173	C	T	exonic	BCL6	synonymous	UCEC\|1\|248\|0.00403
-	chr3	187447178	187447180	AGT	-	exonic	BCL6	nonframeshift	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs377059215	chr3	187447231	187447231	G	A	exonic	BCL6	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr3	187447630	187447630	A	G	exonic	BCL6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	187447542	187447542	C	T	exonic	BCL6	synonymous	CESC\|1\|194\|0.00515
-	chr3	187440319	187440319	G	T	exonic	BCL6	nonsynonymous	ESCA\|1\|185\|0.00541
rs776993725	chr3	187444677	187444677	G	A	exonic	BCL6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	187446181	187446181	C	T	exonic	BCL6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	187451335	187451335	G	A	exonic	BCL6	synonymous	PRAD\|1\|499\|0.00200
-	chr3	187442783	187442783	G	T	exonic	BCL6	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr3	187451396	187451396	T	C	exonic	BCL6	nonsynonymous	UCS\|1\|57\|0.01754
-	chr3	187447483	187447483	G	A	exonic	BCL6	nonsynonymous	BRCA\|1\|982\|0.00102
rs751896144	chr3	187447680	187447680	G	A	exonic	BCL6	synonymous	LIHC\|1\|373\|0.00268
-	chr3	187447718	187447718	C	A	exonic	BCL6	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr3	187446247	187446247	G	A	exonic	BCL6	stopgain	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
rs375595181	chr3	187446201	187446201	G	A	exonic	BCL6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187447287	187447287	T	A	exonic	BCL6	nonsynonymous	UCEC\|1\|248\|0.00403
rs755544927	chr3	187447510	187447510	C	T	exonic	BCL6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187443345	187443345	C	T	exonic	BCL6	nonsynonymous	COAD\|3\|367\|0.00817,COADREAD\|3\|489\|0.00613,UCEC\|1\|248\|0.00403
rs867576130	chr3	187442854	187442854	G	A	exonic	BCL6	nonsynonymous	SKCM\|3\|368\|0.00815
-	chr3	187449635	187449635	C	-	exonic	BCL6	frameshift	UCEC\|1\|248\|0.00403
-	chr3	187447572	187447572	G	A	exonic	BCL6	synonymous	SKCM\|1\|368\|0.00272
-	chr3	187447147	187447147	C	T	exonic	BCL6	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	187444562	187444562	G	A	exonic	BCL6	synonymous	SKCM\|1\|368\|0.00272
-	chr3	187443336	187443336	G	C	exonic	BCL6	nonsynonymous	THCA\|1\|504\|0.00198
-	chr3	187447378	187447378	T	A	exonic	BCL6	nonsynonymous	LIHC\|1\|373\|0.00268
rs781532443	chr3	187449600	187449600	G	A	exonic	BCL6	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr3	187442795	187442795	G	A	exonic	BCL6	synonymous	SKCM\|1\|368\|0.00272
-	chr3	187449545	187449545	A	G	exonic	BCL6	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr3	187449664	187449664	G	A	exonic	BCL6	synonymous	LUSC\|1\|178\|0.00562
-	chr3	187447769	187447769	C	G	exonic	BCL6	nonsynonymous	LUAD\|2\|543\|0.00368
rs369842677	chr3	187446976	187446976	C	T	exonic	BCL6	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr3	187447188	187447188	C	A	exonic	BCL6	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr3	187442758	187442758	G	A	exonic	BCL6	stopgain	UCEC\|1\|248\|0.00403
-	chr3	187447128	187447128	G	T	exonic	BCL6	synonymous	LUAD\|2\|543\|0.00368
-	chr3	187447235	187447235	-	G	exonic	BCL6	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs767642014	chr3	187446270	187446270	G	A	exonic	BCL6	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr3	187449609	187449609	A	G	exonic	BCL6	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr3	187443392	187443392	G	T	exonic	BCL6	synonymous	CESC\|1\|194\|0.00515
-	chr3	187446258	187446258	G	A	exonic	BCL6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	187440320	187440320	C	T	exonic	BCL6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|1\|248\|0.00403
-	chr3	187447093	187447093	G	A	exonic	BCL6	nonsynonymous	UCEC\|1\|248\|0.00403
rs77733730	chr3	187444543	187444543	C	T	exonic	BCL6	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr3	187447566	187447566	G	T	exonic	BCL6	synonymous	UCEC\|1\|248\|0.00403
-	chr3	187444640	187444640	C	T	exonic	BCL6	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	187446240	187446240	G	-	exonic	BCL6	frameshift	PRAD\|1\|499\|0.00200
-	chr3	187447255	187447255	G	A	exonic	BCL6	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr3	187449605	187449605	G	A	exonic	BCL6	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr3	187442794	187442794	G	A	exonic	BCL6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187447463	187447463	G	T	exonic	BCL6	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	187443315	187443315	C	T	exonic	BCL6	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr3	187447317	187447317	G	-	exonic	BCL6	frameshift	HNSC\|1\|512\|0.00195
rs768771889	chr3	187449599	187449599	C	T	exonic	BCL6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187444680	187444680	C	T	exonic	BCL6	nonsynonymous	CESC\|1\|194\|0.00515
-	chr3	187451444	187451444	C	T	exonic	BCL6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187449517	187449517	G	A	exonic	BCL6	synonymous	UCEC\|1\|248\|0.00403
-	chr3	187447343	187447343	C	T	exonic	BCL6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187447539	187447539	C	A	exonic	BCL6	nonsynonymous	LUAD\|1\|543\|0.00184
rs2228258	chr3	187447458	187447458	C	T	exonic	BCL6	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr3	187442788	187442788	G	A	exonic	BCL6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr3	187446838	187446838	C	A	exonic	BCL6	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs866452181	chr3	187449531	187449531	C	A	exonic	BCL6	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr3	187447157	187447157	C	T	exonic	BCL6	nonsynonymous	PAAD\|1\|185\|0.00541
rs147650939	chr3	187444578	187444578	C	T	exonic	BCL6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|1\|248\|0.00403
-	chr3	187447232	187447232	C	T	exonic	BCL6	nonsynonymous	PRAD\|2\|499\|0.00401
-	chr3	187447584	187447584	G	A	exonic	BCL6	synonymous	HNSC\|1\|512\|0.00195
-	chr3	187442826	187442826	T	C	exonic	BCL6	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr3	187446979	187446979	G	A	exonic	BCL6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	187451567	187451567	G	A	intronic	BCL6	unknown	CESC\|1\|194\|0.00515
rs775834769	chr3	187446848	187446848	T	C	exonic	BCL6	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr3	187447102	187447102	G	A	exonic	BCL6	nonsynonymous	HNSC\|1\|512\|0.00195
rs139857005	chr3	187447376	187447376	T	C	exonic	BCL6	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr3	187446895	187446895	G	A	exonic	BCL6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs372779365	chr3	187449515	187449515	C	T	exonic	BCL6	nonsynonymous	UCEC\|1\|248\|0.00403
rs61732778	chr3	187443314	187443314	G	A	exonic	BCL6	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr3	187447392	187447392	T	C	exonic	BCL6	synonymous	LIHC\|1\|373\|0.00268
-	chr3	187440305	187440305	T	C	exonic	BCL6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr3	187440335	187440335	G	A	exonic	BCL6	nonsynonymous	LUAD\|1\|543\|0.00184
rs779270221	chr3	187447775	187447775	G	A	exonic	BCL6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr3	187447652	187447652	C	T	exonic	BCL6	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr3	187443369	187443369	G	T	exonic	BCL6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr3	187447537	187447537	G	T	exonic	BCL6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187447070	187447070	A	G	exonic	BCL6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr3	187447552	187447552	C	A	exonic	BCL6	nonsynonymous	LUAD\|2\|543\|0.00368
-	chr3	187447399	187447399	A	T	exonic	BCL6	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222

Disease information of BCL6

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TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
BCL6	Chronic Lymphocytic Leukemia	C04;C15;C20	Neoplastic Process	CGI
BCL6	Lymphoma, Follicular	C04;C15;C20	Neoplastic Process	ORPHANET
BCL6	Reticulosarcoma	C04;C15;C20	Neoplastic Process	CTD_human
BCL6	Lymphoma, Mixed-Cell	C04;C15;C20	Neoplastic Process	CTD_human
BCL6	Lymphoma, Non-Hodgkin	C04;C15;C20	Neoplastic Process	CGI;CTD_human
BCL6	Lymphoma, Undifferentiated	C04;C15;C20	Neoplastic Process	CTD_human
BCL6	High Grade Lymphoma (neoplasm)	C04;C15;C20	Neoplastic Process	CTD_human
BCL6	Lymphoma, Intermediate-Grade	C04;C15;C20	Neoplastic Process	CTD_human
BCL6	Low Grade Lymphoma (neoplasm)	C04;C15;C20	Neoplastic Process	CTD_human
BCL6	Diffuse Mixed-Cell Lymphoma	C04;C15;C20	Neoplastic Process	CTD_human
BCL6	Lymphoma, Small Noncleaved-Cell	C04;C15;C20	Neoplastic Process	CTD_human
BCL6	T-Cell Lymphoma	C04;C15;C20	Neoplastic Process	CTD_human
BCL6	Angioendotheliomatosis		Neoplastic Process	ORPHANET
BCL6	Mediastinal (Thymic) Large B-Cell Lymphoma		Neoplastic Process	ORPHANET
BCL6	Lymphoma, Diffuse	C04;C15;C20	Neoplastic Process	CTD_human

Pathway associated with BCL6

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pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0000270	BCR	netpath	161	2850
pathway0000271	BCR signaling pathway	pid	70	890
pathway0000608	Direct p53 effectors	pid	141	972
pathway0000827	FoxO family signaling	pid	50	426
pathway0001127	IL4-mediated signaling events	pid	66	512
pathway0002034	Signaling events mediated by HDAC Class II	pid	58	627
pathway0002277	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	reactome	14	26
pathway0002874	Hs_RANKL-RANK_(Receptor_activator_of_NFKB_(ligand))_Signaling_Pathway_WP2018_90016	wikipathways	26	125

Go term information of BCL6

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GO_term_name	GO_term_type	TF_name
GO_REGULATION_OF_DNA_RECOMBINATION	BP	BCL6
GO_REGULATION_OF_LEUKOCYTE_PROLIFERATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE	BP	BCL6
GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	BP	BCL6
GO_REGULATION_OF_CELLULAR_SENESCENCE	BP	BCL6
GO_MYELOID_CELL_DEVELOPMENT	BP	BCL6
GO_REGULATION_OF_HISTONE_DEACETYLATION	BP	BCL6
GO_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS	BP	BCL6
GO_NEGATIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE	BP	BCL6
GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY	BP	BCL6
GO_REGULATION_OF_PROTEIN_DEACETYLATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_DNA_RECOMBINATION	BP	BCL6
GO_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE	BP	BCL6
GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	BP	BCL6
GO_PROTEIN_TARGETING	BP	BCL6
GO_NEGATIVE_REGULATION_OF_B_CELL_ACTIVATION	BP	BCL6
GO_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS	BP	BCL6
GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION	BP	BCL6
GO_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION	BP	BCL6
GO_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY	BP	BCL6
GO_REGULATION_OF_T_HELPER_2_CELL_DIFFERENTIATION	BP	BCL6
GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION	BP	BCL6
GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	BP	BCL6
GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS	BP	BCL6
GO_NEGATIVE_REGULATION_OF_CELL_AGING	BP	BCL6
GO_B_CELL_DIFFERENTIATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE	BP	BCL6
GO_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION	BP	BCL6
GO_POSITIVE_REGULATION_OF_HISTONE_DEACETYLATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION	BP	BCL6
GO_PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION	BP	BCL6
GO_REGULATION_OF_HEMOPOIESIS	BP	BCL6
GO_NEGATIVE_REGULATION_OF_CELL_MATRIX_ADHESION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_HEMOPOIESIS	BP	BCL6
GO_REGULATION_OF_CELL_GROWTH	BP	BCL6
GO_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY	BP	BCL6
GO_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	BP	BCL6
GO_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY	BP	BCL6
GO_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS	BP	BCL6
GO_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS	BP	BCL6
GO_REGULATION_OF_ISOTYPE_SWITCHING	BP	BCL6
GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY	BP	BCL6
GO_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY	BP	BCL6
GO_NEGATIVE_REGULATION_OF_CELLULAR_SENESCENCE	BP	BCL6
GO_CELLULAR_COMPONENT_MORPHOGENESIS	BP	BCL6
GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS	BP	BCL6
GO_POSITIVE_REGULATION_OF_PROTEIN_DEACETYLATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_T_CELL_DIFFERENTIATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	BP	BCL6
GO_MYELOID_CELL_DIFFERENTIATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION	BP	BCL6
GO_POSITIVE_REGULATION_OF_B_CELL_ACTIVATION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS	BP	BCL6
GO_ERYTHROCYTE_DEVELOPMENT	BP	BCL6
GO_REGULATION_OF_CELL_AGING	BP	BCL6
GO_NEGATIVE_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION	BP	BCL6
GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION	BP	BCL6
GO_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE	BP	BCL6
GO_REPLICATION_FORK	CC	BCL6
GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING	MF	BCL6
GO_INTRONIC_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING	MF	BCL6
GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY_SEQUENCE_SPECIFIC_DNA_BINDING	MF	BCL6
GO_CHROMATIN_DNA_BINDING	MF	BCL6

Survival analysis of BCL6

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of BCL6

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)