Sample overview of CLB-GA

Sample ID: Sample_02_298
Biosample type: Cell line
Tissue type: Neuroblastoma
Biosample name: CLB-GA
Data source: NCBI GEO/SRA
GSE ID: GSE90683
Cancer type: Neuroblastoma
CRC number: 73
TF number of all CRCs: 28
TF list of all CRCs: PHOX2B, TFAP2B, RARA, KLF7, HOXD9, LMX1B, JUNB, TBX2, HOXD8, PHOX2A, KLF13, MEIS2, TCF4, TLX2, FOXO3, MEIS1, TEAD1, GATA3, ERF, ISL1, GATA2, CREB1, ETV1, SATB1, MNT, NEUROG2, PROX1, NFIB

The most representative CRC of CLB-GA
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Relationship plot of CRC model
TF number of this CRC: 11
CRC socre: 45.90909
TF list of the most representative CRC
TF name TF family Frequency of TFs
HOXD8 Homeobox 39 / 73
HOXD9 Homeobox 55 / 73
KLF13 zf-C2H2 29 / 73
KLF7 zf-C2H2 56 / 73
LMX1B Homeobox 51 / 73
MEIS1 Homeobox 24 / 73
PHOX2A Homeobox 31 / 73
PHOX2B Homeobox 67 / 73
RARA THR-like 63 / 73
TEAD1 TEA 23 / 73
TFAP2B AP-2 67 / 73

All CRCs of CLB-GA
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
PHOX2B 67 / 73 Homeobox ENSG00000109132
TFAP2B 67 / 73 AP-2 ENSG00000008196
RARA 63 / 73 THR-like ENSG00000131759
KLF7 56 / 73 zf-C2H2 ENSG00000118263
HOXD9 55 / 73 Homeobox ENSG00000128709
LMX1B 51 / 73 Homeobox ENSG00000136944
TBX2 43 / 73 T-box ENSG00000121068
JUNB 43 / 73 TF_bZIP ENSG00000171223
HOXD8 39 / 73 Homeobox ENSG00000175879
PHOX2A 31 / 73 Homeobox ENSG00000165462
KLF13 29 / 73 zf-C2H2 ENSG00000169926
MEIS2 27 / 73 Homeobox ENSG00000134138
TCF4 26 / 73 bHLH ENSG00000196628
TLX2 26 / 73 Homeobox ENSG00000115297
FOXO3 25 / 73 Fork_head ENSG00000118689
MEIS1 24 / 73 Homeobox ENSG00000143995
TEAD1 23 / 73 TEA ENSG00000187079
ERF 22 / 73 ETS ENSG00000105722
GATA3 22 / 73 zf-GATA ENSG00000107485
ISL1 21 / 73 Homeobox ENSG00000016082
GATA2 18 / 73 zf-GATA ENSG00000179348
CREB1 8 / 73 TF_bZIP ENSG00000118260
ETV1 8 / 73 NA NA
SATB1 7 / 73 CUT ENSG00000182568
MNT 5 / 73 bHLH ENSG00000070444
PROX1 4 / 73 HPD ENSG00000117707
NEUROG2 4 / 73 bHLH ENSG00000178403
NFIB 2 / 73 CTF/NFI ENSG00000147862

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
TCF4 32 37 69
ISL1 29 35 64
JUNB 33 37 70
TBX2 30 40 70
ERF 32 28 60
TEAD1 29 41 70
RARA 31 45 76
TFAP2B 30 46 76
MNT 21 27 48
MEIS2 27 42 69
MEIS1 24 43 67
PROX1 30 19 49
KLF7 31 42 73
NEUROG2 20 29 49
KLF13 30 41 71
HOXD8 30 42 72
HOXD9 30 42 72
NFIB 5 28 33
CREB1 25 35 60
LMX1B 27 44 71
SATB1 24 39 63
PHOX2A 29 42 71
PHOX2B 32 43 75
GATA2 30 36 66
GATA3 30 41 71
ETV1 23 24 47
FOXO3 27 45 72
TLX2 24 43 67

Expression of TFs in all CRCs