TF information

TF name: HOXD9
TF family: Homeobox
Ensembl gene ID: ENSG00000128709
Ensembl protein ID: ENSP00000249499
Entrez gene ID: 3235
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of HOXD9 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_114Cell lineMammary GlandCAL510.4070351758794
Sample_02_298Cell lineNeuroblastomaCLB-GA0.75342465753425
Sample_02_299Cell lineNeuroblastomaCLB-MA0.016786570743405
Sample_02_300Cell lineNeuroblastomaCLB-PE0.64102564102564
Sample_02_311Cell lineNeuroblastomaSK-N-AS0.77922077922078
Sample_02_316Cell lineNeuroblastomaCHP2120.85164835164835
Sample_02_318Cell lineNeuroblastomaNB690.9453125

HOXD9 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_298NeuroblastomaCell lineCLB-GA
Sample_02_300NeuroblastomaCell lineCLB-PE
Sample_02_311NeuroblastomaCell lineSK-N-AS
Sample_02_316NeuroblastomaCell lineCHP212
Sample_02_318NeuroblastomaCell lineNB69

HOXD9 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with HOXD9
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Mutation of HOXD9
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of HOXD9

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr2176988888176988888CTexonicHOXD9synonymous UCEC|1|248|0.00403
-chr2176988685176988685CTexonicHOXD9nonsynonymous BLCA|1|396|0.00253
-chr2176988684176988684CTexonicHOXD9synonymous UCEC|1|248|0.00403
-chr2176988882176988882GTexonicHOXD9nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr2176987530176987530TAexonicHOXD9nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr2176988850176988850CAexonicHOXD9nonsynonymous GBM|1|290|0.00345,GBMLGG|1|820|0.00122
-chr2176987685176987685CTexonicHOXD9synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr2176987785176987785CAexonicHOXD9nonsynonymous LUAD|1|543|0.00184
-chr2176987600176987600CTexonicHOXD9nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr2176987568176987568GAexonicHOXD9synonymous PAAD|1|185|0.00541
-chr2176988747176988747GTexonicHOXD9nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
rs35649704chr2176988765176988765CTexonicHOXD9synonymous DLBC|1|48|0.02083
-chr2176987716176987716GAexonicHOXD9nonsynonymous SKCM|1|368|0.00272
-chr2176988776176988776CTexonicHOXD9nonsynonymous HNSC|1|512|0.00195
rs778452592chr2176988257176988257CTexonicHOXD9nonsynonymous SKCM|2|368|0.00543
rs758440041chr2176988158176988158-GexonicHOXD9frameshift COAD|1|367|0.00272,COADREAD|2|489|0.00409,READ|1|122|0.00820
-chr2176987556176987556CAexonicHOXD9stopgain PRAD|1|499|0.00200
rs200391181chr2176988303176988303AGexonicHOXD9synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr2176988751176988751GCexonicHOXD9nonsynonymous CESC|1|194|0.00515
-chr2176987764176987764GTexonicHOXD9nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs751672056chr2176988212176988212CTexonicHOXD9nonsynonymous TGCT|1|155|0.00645
-chr2176988234176988234CAexonicHOXD9nonsynonymous LUAD|1|543|0.00184
-chr2176988295176988295CTexonicHOXD9stopgain COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr2176988678176988678CAexonicHOXD9nonsynonymous LUAD|1|543|0.00184
rs200417886chr2176988290176988290CAexonicHOXD9nonsynonymous CHOL|1|35|0.02857
-chr2176987697176987697T-exonicHOXD9frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr2176987564176987564AGexonicHOXD9nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr2176988179176988179CTexonicHOXD9nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr2176987592176987592GCexonicHOXD9nonsynonymous LUSC|1|178|0.00562
-chr2176988200176988200GTexonicHOXD9nonsynonymous HNSC|1|512|0.00195
-chr2176988855176988855GTexonicHOXD9nonsynonymous CHOL|1|35|0.02857
-chr2176988775176988775AGexonicHOXD9nonsynonymous SKCM|1|368|0.00272
-chr2176987559176987559CTexonicHOXD9synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr2176987826176987826CTexonicHOXD9synonymous UCS|1|57|0.01754
-chr2176987711176987711CGexonicHOXD9nonsynonymous LUSC|1|178|0.00562
rs377282327chr2176988216176988216GAexonicHOXD9synonymous LUAD|1|543|0.00184
-chr2176988265176988265GCexonicHOXD9nonsynonymous LIHC|1|373|0.00268
-chr2176988789176988789CTexonicHOXD9synonymous LUAD|1|543|0.00184
-chr2176988304176988304CAexonicHOXD9nonsynonymous UCEC|1|248|0.00403
-chr2176987735176987735CAexonicHOXD9nonsynonymous LUAD|1|543|0.00184
-chr2176988902176988902GTexonicHOXD9stoploss LUAD|1|543|0.00184
-chr2176988709176988709CTexonicHOXD9nonsynonymous UCEC|1|248|0.00403

Disease information of HOXD9
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
HOXD9 Mucinous Adenocarcinoma C04 Neoplastic Process CTD_human
HOXD9 Colorectal Carcinoma C04;C06 Neoplastic Process CTD_human
HOXD9 Colorectal Neoplasms C04;C06 Neoplastic Process CTD_human
HOXD9 Neoplastic Processes C04;C23 Neoplastic Process CTD_human
HOXD9 ovarian neoplasm C04;C13;C19 Neoplastic Process CTD_human
HOXD9 Malignant neoplasm of ovary C04;C13;C19 Neoplastic Process CTD_human
HOXD9 Colorectal Cancer C04;C06 Neoplastic Process CTD_human

Pathway associated with HOXD9
pathway_ID pathway_name pathway_source gene_number edge_number

Go term information of HOXD9
GO_term_name GO_term_type TF_name
GO_MUSCLE_TISSUE_DEVELOPMENT BP HOXD9
GO_SINGLE_ORGANISM_BEHAVIOR BP HOXD9
GO_HINDLIMB_MORPHOGENESIS BP HOXD9
GO_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS BP HOXD9
GO_FORELIMB_MORPHOGENESIS BP HOXD9
GO_PROXIMAL_DISTAL_PATTERN_FORMATION BP HOXD9
GO_EMBRYONIC_FORELIMB_MORPHOGENESIS BP HOXD9
GO_PERIPHERAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION BP HOXD9
GO_PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT BP HOXD9

Survival analysis of HOXD9



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of HOXD9