Sample overview of CLB-PE

Sample ID: Sample_02_300
Biosample type: Cell line
Tissue type: Neuroblastoma
Biosample name: CLB-PE
Data source: NCBI GEO/SRA
GSE ID: GSE90683
Cancer type: Neuroblastoma
CRC number: 78
TF number of all CRCs: 24
TF list of all CRCs: JUNB, HOXD9, GLI2, RXRA, PHOX2A, KLF13, PHOX2B, FOXO3, MEIS2, TCF4, KLF7, TLX2, HOXD8, TBX2, ZBTB7B, SREBF1, ERF, E2F2, TEAD1, NEUROG2, ETV6, PROX1, SIX3, CEBPB

The most representative CRC of CLB-PE
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Relationship plot of CRC model
TF number of this CRC: 9
CRC socre: 41.77778
TF list of the most representative CRC
TF name TF family Frequency of TFs
GLI2 zf-C2H2 48 / 78
HOXD9 Homeobox 50 / 78
JUNB TF_bZIP 56 / 78
KLF13 zf-C2H2 40 / 78
PHOX2A Homeobox 41 / 78
PHOX2B Homeobox 37 / 78
RXRA RXR-like 44 / 78
TCF4 bHLH 31 / 78
TLX2 Homeobox 29 / 78

All CRCs of CLB-PE
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
JUNB 56 / 78 TF_bZIP ENSG00000171223
HOXD9 50 / 78 Homeobox ENSG00000128709
GLI2 48 / 78 zf-C2H2 ENSG00000074047
RXRA 44 / 78 RXR-like ENSG00000186350
PHOX2A 41 / 78 Homeobox ENSG00000165462
KLF13 40 / 78 zf-C2H2 ENSG00000169926
PHOX2B 37 / 78 Homeobox ENSG00000109132
FOXO3 36 / 78 Fork_head ENSG00000118689
MEIS2 34 / 78 Homeobox ENSG00000134138
KLF7 31 / 78 zf-C2H2 ENSG00000118263
TCF4 31 / 78 bHLH ENSG00000196628
TLX2 29 / 78 Homeobox ENSG00000115297
HOXD8 26 / 78 Homeobox ENSG00000175879
TBX2 22 / 78 T-box ENSG00000121068
ZBTB7B 18 / 78 ZBTB ENSG00000160685
SREBF1 16 / 78 bHLH ENSG00000072310
E2F2 14 / 78 E2F ENSG00000007968
ERF 14 / 78 ETS ENSG00000105722
TEAD1 11 / 78 TEA ENSG00000187079
NEUROG2 8 / 78 bHLH ENSG00000178403
ETV6 7 / 78 ETS ENSG00000139083
PROX1 6 / 78 HPD ENSG00000117707
SIX3 4 / 78 Homeobox ENSG00000138083
CEBPB 3 / 78 TF_bZIP ENSG00000172216

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
TCF4 26 36 62
TBX2 21 43 64
ERF 26 26 52
TEAD1 19 42 61
KLF13 24 42 66
GLI2 25 36 61
MEIS2 21 45 66
SIX3 22 26 48
KLF7 23 38 61
NEUROG2 18 30 48
JUNB 26 37 63
HOXD8 24 39 63
HOXD9 24 44 68
ZBTB7B 19 36 55
RXRA 23 44 67
PHOX2A 25 40 65
PHOX2B 25 40 65
PROX1 24 19 43
FOXO3 23 47 70
CEBPB 20 33 53
E2F2 19 34 53
ETV6 13 44 57
TLX2 18 46 64
SREBF1 22 37 59

Expression of TFs in all CRCs