Sample overview of T-47D_1

Sample ID: Sample_02_079
Biosample type: Cell line
Tissue type: Mammary Gland
Biosample name: T-47D_1
Data source: NCBI GEO/SRA
GSE ID: GSE63109
Cancer type: breast adenocarcinoma
CRC number: 9
TF number of all CRCs: 19
TF list of all CRCs: GATA3, TFAP2A, BACH1, SPDEF, ESR1, HES1, EHF, PBX1, RARA, FOXA1, HOXC10, XBP1, HOXB2, MSX2, HOXC9, ZBTB7B, BARX2, MAFK, RXRA

The most representative CRC of T-47D_1
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Relationship plot of CRC model
TF number of this CRC: 11
CRC socre: 7.454545
TF list of the most representative CRC
TF name TF family Frequency of TFs
BACH1 TF_bZIP 9 / 9
BARX2 Homeobox 3 / 9
EHF ETS 9 / 9
ESR1 ESR-like 9 / 9
GATA3 zf-GATA 9 / 9
HES1 bHLH 9 / 9
HOXB2 Homeobox 4 / 9
PBX1 Homeobox 7 / 9
SPDEF ETS 9 / 9
TFAP2A AP-2 9 / 9
XBP1 TF_bZIP 5 / 9

All CRCs of T-47D_1
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
SPDEF 9 / 9 ETS ENSG00000124664
TFAP2A 9 / 9 AP-2 ENSG00000137203
BACH1 9 / 9 TF_bZIP ENSG00000156273
EHF 9 / 9 ETS ENSG00000135373
ESR1 9 / 9 ESR-like ENSG00000091831
GATA3 9 / 9 zf-GATA ENSG00000107485
HES1 9 / 9 bHLH ENSG00000114315
PBX1 7 / 9 Homeobox ENSG00000185630
RARA 6 / 9 THR-like ENSG00000131759
FOXA1 6 / 9 Fork_head ENSG00000129514
HOXC10 6 / 9 Homeobox ENSG00000180818
XBP1 5 / 9 TF_bZIP ENSG00000100219
ZBTB7B 4 / 9 ZBTB ENSG00000160685
HOXB2 4 / 9 Homeobox ENSG00000173917
HOXC9 4 / 9 Homeobox ENSG00000180806
MSX2 4 / 9 Homeobox ENSG00000120149
BARX2 3 / 9 Homeobox ENSG00000043039
MAFK 3 / 9 TF_bZIP ENSG00000198517
RXRA 2 / 9 RXR-like ENSG00000186350

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
HOXC9 18 30 48
MAFK 17 33 50
XBP1 19 28 47
RARA 18 33 51
TFAP2A 19 32 51
BACH1 19 30 49
MSX2 18 31 49
ZBTB7B 17 32 49
HOXB2 19 24 43
RXRA 15 33 48
EHF 19 33 52
HOXC10 18 32 50
GATA3 19 33 52
PBX1 19 29 48
BARX2 19 23 42
ESR1 19 33 52
SPDEF 19 33 52
FOXA1 18 30 48
HES1 19 31 50

Expression of TFs in all CRCs