TF information

TF name: HES7
TF family: bHLH
Ensembl gene ID: ENSG00000179111
Ensembl protein ID: ENSP00000314774, ENSP00000446205, ENSP00000462491
Entrez gene ID: 84667
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of HES7 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_069Cell lineBrainSF2680.030534351145038
Sample_02_280Cell lineMammary GlandSUM159_DMSO_24h0.041666666666667

HES7 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name

HES7 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with HES7
Download

Mutation of HES7
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of HES7

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr1780252308025230C-exonicHES7frameshift LUAD|1|543|0.00184
-chr1780251008025100GAexonicHES7nonsynonymous HNSC|1|512|0.00195
-chr1780249748024974GAexonicHES7nonsynonymous KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr1780263948026394GCexonicHES7nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs61731639chr1780263648026364CTexonicHES7synonymous ACC|1|90|0.01111

Disease information of HES7
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
HES7 Jarcho-Levin syndrome C16;C23 Disease or Syndrome ORPHANET
HES7 SPONDYLOCOSTAL DYSOSTOSIS, AUTOSOMAL RECESSIVE 2 C05 Disease or Syndrome CTD_human
HES7 SPONDYLOCOSTAL DYSOSTOSIS, AUTOSOMAL RECESSIVE 3 C05 Disease or Syndrome CTD_human
HES7 SPONDYLOCOSTAL DYSOSTOSIS 4, AUTOSOMAL RECESSIVE Disease or Syndrome UNIPROT

Pathway associated with HES7
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0002825 Hs_Gene_regulatory_network_modelling_somitogenesis_WP2854_87527 wikipathways 12 26
pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 wikipathways 47 175

Go term information of HES7
GO_term_name GO_term_type TF_name
GO_SOMITOGENESIS BP HES7
GO_SEGMENTATION BP HES7
GO_RHYTHMIC_PROCESS BP HES7
GO_REGULATION_OF_EMBRYONIC_DEVELOPMENT BP HES7
GO_POST_ANAL_TAIL_MORPHOGENESIS BP HES7
GO_MESODERM_DEVELOPMENT BP HES7
GO_SOMITE_DEVELOPMENT BP HES7

Survival analysis of HES7



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of HES7