1. TF detail

TF information

TF name: FOXG1
TF family: Fork_head
Ensembl gene ID: ENSG00000176165
Ensembl protein ID: ENSP00000339004
Entrez gene ID: 2290
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:
Frequency of FOXG1 in all biosamples
Download
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_069Cell lineBrainSF2680.86259541984733
Sample_02_258OtherLungNCI-H1299_EGFP-NEO_reporter_cells_DMSO0.055555555555556
Sample_02_413TissueBrainGBM_24930.66483516483516
FOXG1 distribution in samples’ most representative CRC
Download
Sample ID Tissue type Biosample type Biosample name
Sample_02_069BrainCell lineSF268
Sample_02_413BrainTissueGBM_2493
FOXG1 distribution in all CRCs
Biosample type
Biosample name
Sample ID
Genomic distribution of SEs associated with FOXG1
Download
Mutation of FOXG1
Download
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of FOXG1

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr142923786529237865GCexonicFOXG1nonsynonymous OV|1|469|0.00213
-chr142923749429237494CAexonicFOXG1nonsynonymous LUAD|1|543|0.00184
-chr142923784529237845GCexonicFOXG1nonsynonymous HNSC|1|512|0.00195
-chr142923759829237598GTexonicFOXG1nonsynonymous UCEC|1|248|0.00403
rs786205007chr142923717429237174GAexonicFOXG1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204,LUAD|1|543|0.00184
-chr142923744329237443CAexonicFOXG1nonsynonymous ACC|1|90|0.01111
-chr142923716929237169CAexonicFOXG1synonymous HNSC|1|512|0.00195
-chr142923785529237855GTexonicFOXG1nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr142923731729237317AGexonicFOXG1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923744529237445CTexonicFOXG1synonymous ACC|1|90|0.01111
-chr142923762929237629GAexonicFOXG1nonsynonymous PAAD|1|185|0.00541
rs746727507chr142923740029237400CTexonicFOXG1synonymous SKCM|2|368|0.00543
-chr142923654129236541GTexonicFOXG1nonsynonymous HNSC|1|512|0.00195
-chr142923721429237214GAexonicFOXG1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr142923747429237474CAexonicFOXG1nonsynonymous LUSC|1|178|0.00562
-chr142923730729237307GTexonicFOXG1synonymous LUAD|1|543|0.00184
-chr142923735529237355GCexonicFOXG1synonymous LUSC|1|178|0.00562
-chr142923793629237936CTexonicFOXG1nonsynonymous SKCM|1|368|0.00272
rs786205008chr142923718529237185TCexonicFOXG1nonsynonymous UCEC|1|248|0.00403
-chr142923777229237772G-exonicFOXG1frameshift LUAD|2|543|0.00368
-chr142923748129237481GAexonicFOXG1synonymous LUSC|1|178|0.00562
-chr142923783729237837TAexonicFOXG1nonsynonymous LUAD|1|543|0.00184
-chr142923781829237818CAexonicFOXG1nonsynonymous LUAD|1|543|0.00184
-chr142923781129237811CTexonicFOXG1synonymous BRCA|1|982|0.00102
rs369183477chr142923788029237880GAexonicFOXG1synonymous BLCA|1|396|0.00253,UCEC|1|248|0.00403
-chr142923656029236560CTexonicFOXG1synonymous BLCA|1|396|0.00253
-chr142923704729237047GAexonicFOXG1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923711029237110GAexonicFOXG1nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr142923781829237818CTexonicFOXG1nonsynonymous UCEC|1|248|0.00403
-chr142923711329237113TCexonicFOXG1nonsynonymous PRAD|1|499|0.00200
-chr142923734829237348GAexonicFOXG1nonsynonymous LIHC|1|373|0.00268
-chr142923728729237287GCexonicFOXG1nonsynonymous LUAD|1|543|0.00184
-chr142923718529237185TGexonicFOXG1nonsynonymous GBM|1|290|0.00345,GBMLGG|1|820|0.00122
-chr142923662529236626AC-exonicFOXG1frameshift GBM|2|290|0.00690,GBMLGG|2|820|0.00244,UVM|1|80|0.01250
-chr142923721729237217CAexonicFOXG1synonymous LIHC|1|373|0.00268
-chr142923776929237769GAexonicFOXG1synonymous ACC|1|90|0.01111,COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr142923753129237531CTexonicFOXG1nonsynonymous UCEC|1|248|0.00403
-chr142923753129237531CAexonicFOXG1stopgain LIHC|1|373|0.00268
-chr142923706429237064CGexonicFOXG1synonymous LUAD|1|543|0.00184
-chr142923768729237687CTexonicFOXG1nonsynonymous SKCM|1|368|0.00272
-chr142923736129237361CTexonicFOXG1synonymous BLCA|1|396|0.00253
-chr142923711729237117TCexonicFOXG1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923706829237068CTexonicFOXG1nonsynonymous HNSC|1|512|0.00195
rs376242569chr142923779829237798CTexonicFOXG1nonsynonymous PRAD|1|499|0.00200
-chr142923783129237831CTexonicFOXG1nonsynonymous BLCA|1|396|0.00253,HNSC|1|512|0.00195,LUAD|1|543|0.00184
-chr142923704929237049GTexonicFOXG1synonymous LUAD|1|543|0.00184
-chr142923712429237124GTexonicFOXG1nonsynonymous BLCA|1|396|0.00253
-chr142923764529237645CAexonicFOXG1stopgain LUAD|1|543|0.00184
-chr142923761129237611AGexonicFOXG1nonsynonymous ESCA|1|185|0.00541
-chr142923709629237096TCexonicFOXG1nonsynonymous LIHC|1|373|0.00268
-chr142923753529237535GAexonicFOXG1synonymous LUAD|1|543|0.00184
-chr142923778429237784CAexonicFOXG1synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923722029237220CTexonicFOXG1synonymous OV|1|469|0.00213
-chr142923739129237391CTexonicFOXG1synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923785929237859CAexonicFOXG1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr142923703729237037CGexonicFOXG1nonsynonymous BLCA|1|396|0.00253
-chr142923701329237013CAexonicFOXG1nonsynonymous LUAD|1|543|0.00184
-chr142923724929237249GAexonicFOXG1stopgain SKCM|1|368|0.00272
-chr142923741629237416TAexonicFOXG1nonsynonymous LIHC|1|373|0.00268
-chr142923782129237821CAexonicFOXG1nonsynonymous LUAD|1|543|0.00184
-chr142923739929237399CTexonicFOXG1nonsynonymous SKCM|1|368|0.00272
-chr142923735829237358CTexonicFOXG1synonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr142923696329236988GGCGAGGGCGGCAAGGACGGGGAGGG-exonicFOXG1frameshift GBM|1|290|0.00345,GBMLGG|1|820|0.00122
rs747996412chr142923759229237592CTexonicFOXG1synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923722729237227GAexonicFOXG1nonsynonymous LUSC|1|178|0.00562
-chr142923756029237560GAexonicFOXG1nonsynonymous ESCA|1|185|0.00541
rs755296509chr142923701329237013CTexonicFOXG1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr142923768929237689CTexonicFOXG1nonsynonymous BLCA|1|396|0.00253
-chr142923772129237721CAexonicFOXG1synonymous LUAD|1|543|0.00184
-chr142923784029237840CTexonicFOXG1nonsynonymous PAAD|1|185|0.00541
rs780242359chr142923775829237758TCexonicFOXG1nonsynonymous ESCA|1|185|0.00541
-chr142923733329237333AGexonicFOXG1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923794729237947AGexonicFOXG1nonsynonymous LUAD|1|543|0.00184
rs770118439chr142923780129237801CTexonicFOXG1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr142923783529237835CTexonicFOXG1synonymous SKCM|1|368|0.00272
rs752379833chr142923786929237869AGexonicFOXG1nonsynonymous ESCA|1|185|0.00541
-chr142923700329237003ACexonicFOXG1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr142923786929237869ACexonicFOXG1nonsynonymous ESCA|1|185|0.00541
rs869312700chr142923730629237306GAexonicFOXG1nonsynonymous LUAD|1|543|0.00184
-chr142923782029237820GAexonicFOXG1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr142923771229237712GAexonicFOXG1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204,LIHC|1|373|0.00268
-chr142923774229237742CTexonicFOXG1synonymous HNSC|1|512|0.00195
rs756638761chr142923703429237034GAexonicFOXG1synonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
rs796052469chr142923729729237297GAexonicFOXG1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923719729237197TAexonicFOXG1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923791729237917CGexonicFOXG1nonsynonymous BLCA|1|396|0.00253
-chr142923701829237018ACexonicFOXG1nonsynonymous ESCA|2|185|0.01081
-chr142923792529237925GCexonicFOXG1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr142923784929237849CTexonicFOXG1nonsynonymous BLCA|1|396|0.00253
-chr142923718729237187CAexonicFOXG1synonymous LUAD|1|543|0.00184
-chr142923787729237877GAexonicFOXG1synonymous PRAD|1|499|0.00200
rs777770149chr142923773929237739CTexonicFOXG1synonymous SKCM|1|368|0.00272
-chr142923705629237056AGexonicFOXG1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923651029236510GCexonicFOXG1nonsynonymous CESC|1|194|0.00515
-chr142923698329236983GAexonicFOXG1synonymous LIHC|1|373|0.00268
-chr142923774929237749CTexonicFOXG1nonsynonymous SKCM|1|368|0.00272
-chr142923750429237504CAexonicFOXG1nonsynonymous LUAD|1|543|0.00184
-chr142923730529237305CTexonicFOXG1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204,STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923779629237796GTexonicFOXG1nonsynonymous LUAD|1|543|0.00184
-chr142923721829237218CAexonicFOXG1nonsynonymous LUSC|1|178|0.00562
-chr142923774629237746GAexonicFOXG1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr142923763029237630CTexonicFOXG1nonsynonymous ESCA|1|185|0.00541
-chr142923650129236501GAexonicFOXG1nonsynonymous PAAD|1|185|0.00541
rs763497415chr142923767329237673CTexonicFOXG1synonymous LUAD|1|543|0.00184
-chr142923762829237628CTexonicFOXG1synonymous BRCA|1|982|0.00102
rs869312717chr142923693929236939G-exonicFOXG1frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923659329236593CTexonicFOXG1synonymous PAAD|1|185|0.00541
-chr142923789029237890GTexonicFOXG1nonsynonymous LUSC|1|178|0.00562
-chr142923751429237514CTexonicFOXG1synonymous HNSC|2|512|0.00391
-chr142923719529237195AGexonicFOXG1nonsynonymous PAAD|1|185|0.00541
-chr142923705829237058GCexonicFOXG1nonsynonymous HNSC|1|512|0.00195
-chr142923764029237640CTexonicFOXG1synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923752729237527ACexonicFOXG1nonsynonymous HNSC|1|512|0.00195
-chr142923732729237327GCexonicFOXG1nonsynonymous LUAD|1|543|0.00184
-chr142923700729237007GAexonicFOXG1synonymous CESC|1|194|0.00515,HNSC|1|512|0.00195
-chr142923704629237046CTexonicFOXG1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr142923760829237608GTexonicFOXG1nonsynonymous HNSC|1|512|0.00195
-chr142923729029237290ACexonicFOXG1nonsynonymous SKCM|1|368|0.00272
-chr142923760529237605TCexonicFOXG1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923721529237215CAexonicFOXG1nonsynonymous ESCA|1|185|0.00541
-chr142923778029237780C-exonicFOXG1frameshift UCEC|1|248|0.00403
-chr142923781729237817GAexonicFOXG1synonymous LUAD|1|543|0.00184
rs121913678chr142923725029237250GTexonicFOXG1nonsynonymous LUAD|1|543|0.00184
rs267606826chr142923710929237109CTexonicFOXG1synonymous ESCA|1|185|0.00541
-chr142923789029237890G-exonicFOXG1frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923717229237172CAexonicFOXG1synonymous LUAD|1|543|0.00184
-chr142923704829237048CTexonicFOXG1nonsynonymous UCS|1|57|0.01754
-chr142923771429237714TGexonicFOXG1nonsynonymous LUSC|1|178|0.00562
rs774246700chr142923746929237469CTexonicFOXG1synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923748029237480CTexonicFOXG1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923787929237879CTexonicFOXG1nonsynonymous ESCA|1|185|0.00541,UCEC|1|248|0.00403
-chr142923715429237154GTexonicFOXG1nonsynonymous LUAD|1|543|0.00184
rs570340475chr142923732229237322CTexonicFOXG1synonymous GBM|1|290|0.00345,GBMLGG|1|820|0.00122
rs757300535chr142923775729237757GAexonicFOXG1synonymous HNSC|1|512|0.00195,STAD|1|395|0.00253,STES|1|395|0.00253,UCEC|1|248|0.00403
-chr142923781429237814GAexonicFOXG1synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923743929237439CTexonicFOXG1synonymous HNSC|1|512|0.00195
-chr142923717329237173CGexonicFOXG1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr142923737229237372GTexonicFOXG1nonsynonymous LUAD|1|543|0.00184
-chr142923703329237033CTexonicFOXG1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr142923743029237430CTexonicFOXG1synonymous SKCM|1|368|0.00272
-chr142923752229237522CTexonicFOXG1nonsynonymous SKCM|1|368|0.00272
-chr142923739529237395GAexonicFOXG1nonsynonymous HNSC|1|512|0.00195
-chr142923763329237633CTexonicFOXG1nonsynonymous ESCA|1|185|0.00541
-chr142923739029237390GAexonicFOXG1nonsynonymous PRAD|2|499|0.00401
-chr142923771529237715CTexonicFOXG1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204,LUAD|1|543|0.00184
Disease information of FOXG1
Download
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
FOXG1 Profound Mental Retardation C10;C23;F01;F03 Mental or Behavioral Dysfunction CTD_human
FOXG1 Jacksonian Seizure C10;C23 Disease or Syndrome CTD_human
FOXG1 Mental Retardation, Psychosocial C10;C23;F01;F03 Mental or Behavioral Dysfunction CTD_human
FOXG1 Microcephaly C05;C10;C16 Congenital Abnormality CTD_human;GENOMICS_ENGLAND
FOXG1 nervous system disorder C10 Disease or Syndrome CTD_human
FOXG1 Seizures C10;C23 Sign or Symptom CTD_human
FOXG1 Complex partial seizures C10;C23 Disease or Syndrome CTD_human
FOXG1 Generalized seizures C10;C23 Disease or Syndrome CTD_human
FOXG1 Seizures, Clonic C10;C23 Disease or Syndrome CTD_human
FOXG1 Visual seizure C10;C23 Disease or Syndrome CTD_human
FOXG1 Tonic Seizures C10;C23 Sign or Symptom CTD_human
FOXG1 Epileptic drop attack C10;C23 Disease or Syndrome CTD_human
FOXG1 Seizures, Somatosensory C10;C23 Pathologic Function CTD_human
FOXG1 Seizures, Auditory C10;C23 Pathologic Function CTD_human
FOXG1 Olfactory seizure C10;C23 Disease or Syndrome CTD_human
FOXG1 Gustatory seizure C10;C23 Sign or Symptom CTD_human
FOXG1 Vertiginous seizure C10;C23 Disease or Syndrome CTD_human
FOXG1 Tonic - clonic seizures C10;C23 Disease or Syndrome CTD_human
FOXG1 Epileptic encephalopathy Disease or Syndrome GENOMICS_ENGLAND
FOXG1 Non-epileptic convulsion C10;C23 Sign or Symptom CTD_human
FOXG1 Single Seizure C10;C23 Disease or Syndrome CTD_human
FOXG1 Atonic Absence Seizures C10;C23 Disease or Syndrome CTD_human
FOXG1 Convulsive Seizures C10;C23 Sign or Symptom CTD_human
FOXG1 Seizures, Focal C10;C23 Disease or Syndrome CTD_human
FOXG1 Seizures, Sensory C10;C23 Sign or Symptom CTD_human
FOXG1 Acrocallosal Syndrome C10;C16 Disease or Syndrome CTD_human
FOXG1 Mental deficiency C10;C23;F01;F03 Mental or Behavioral Dysfunction CTD_human
FOXG1 Microlissencephaly C05;C10;C16 Disease or Syndrome CTD_human
FOXG1 Rett Syndrome, Atypical C10;C16 Disease or Syndrome ORPHANET
FOXG1 FOXG1 syndrome Disease or Syndrome CTD_human;UNIPROT
FOXG1 Nonepileptic Seizures C10;C23 Disease or Syndrome CTD_human
FOXG1 Intellectual Disability C10;C23;F01;F03 Mental or Behavioral Dysfunction CTD_human;GENOMICS_ENGLAND
FOXG1 Severe Congenital Microcephaly C05;C10;C16 Congenital Abnormality; Disease or Syndrome CTD_human
FOXG1 Convulsions C10;C23 Sign or Symptom CTD_human
FOXG1 14q12 microdeletion syndrome Disease or Syndrome ORPHANET
FOXG1 Absence Seizures C10;C23 Sign or Symptom CTD_human
FOXG1 Epileptic Seizures C10;C23 Disease or Syndrome CTD_human
FOXG1 Myoclonic Seizures C10;C23 Sign or Symptom CTD_human
FOXG1 Generalized Absence Seizures C10;C23 Disease or Syndrome CTD_human
Pathway associated with FOXG1
Download
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0001849 Regulation of nuclear SMAD2/3 signaling pid 82 1072
Go term information of FOXG1
Download
GO_term_name GO_term_type TF_name

Survival analysis of FOXG1


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of FOXG1

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)