TF information

TF name: CDX1
TF family: Homeobox
Ensembl gene ID: ENSG00000113722
Ensembl protein ID: ENSP00000477928, ENSP00000231656
Entrez gene ID: 1044
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of CDX1 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_242Cell lineColonV4810.209510991476
Sample_02_296Cell lineNeuroblastomaCLB-BER-Lud0.1017597551645
Sample_02_304Cell lineNeuroblastomaN2060.18478260869565

CDX1 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name

CDX1 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with CDX1
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Mutation of CDX1
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of CDX1

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr5149563122149563122CAexonicCDX1nonsynonymous LUAD|1|543|0.00184
-chr5149562382149562382GTexonicCDX1nonsynonymous PRAD|2|499|0.00401
-chr5149546487149546487CGexonicCDX1synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr5149562461149562461GAexonicCDX1synonymous HNSC|2|512|0.00391
rs140956520chr5149562432149562432CTexonicCDX1nonsynonymous BLCA|1|396|0.00253,UCEC|1|248|0.00403
-chr5149546471149546471CTexonicCDX1nonsynonymous SKCM|2|368|0.00543
rs763613197chr5149546520149546520GAexonicCDX1synonymous TGCT|1|155|0.00645
-chr5149546531149546531-CexonicCDX1frameshift LUAD|1|543|0.00184
-chr5149563112149563112CTexonicCDX1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr5149562339149562339CAexonicCDX1synonymous HNSC|2|512|0.00391
-chr5149563090149563090GAexonicCDX1synonymous SKCM|1|368|0.00272
-chr5149562381149562381CAexonicCDX1nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr5149563195149563195CTexonicCDX1synonymous SKCM|1|368|0.00272
rs753003920chr5149562371149562371CTexonicCDX1synonymous OV|1|469|0.00213
-chr5149563070149563070GAexonicCDX1nonsynonymous SKCM|2|368|0.00543
rs777049283chr5149563133149563133GAexonicCDX1nonsynonymous SKCM|1|368|0.00272
-chr5149563163149563163CAexonicCDX1nonsynonymous LUAD|1|543|0.00184
-chr5149562369149562369AGexonicCDX1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr5149546485149546485GAexonicCDX1nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr5149563073149563073CGexonicCDX1nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr5149563178149563178CTexonicCDX1nonsynonymous SKCM|2|368|0.00543
rs768479920chr5149562398149562398GTexonicCDX1nonsynonymous DLBC|1|48|0.02083
-chr5149562428149562428CTexonicCDX1synonymous SKCM|1|368|0.00272
-chr5149563052149563052CTexonicCDX1stopgain LUAD|1|543|0.00184

Disease information of CDX1
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source

Pathway associated with CDX1
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0001848 Regulation of nuclear beta catenin signaling and target gene transcription pid 80 611

Go term information of CDX1
GO_term_name GO_term_type TF_name
GO_BONE_DEVELOPMENT BP CDX1
GO_ANTERIOR_POSTERIOR_AXIS_SPECIFICATION BP CDX1
GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_BINDING MF CDX1
GO_ENHANCER_BINDING MF CDX1
GO_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_DNA_BINDING MF CDX1

Survival analysis of CDX1



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of CDX1