Sample overview of CJM

Sample ID: Sample_02_180
Biosample type: Cell line
Tissue type: Human melanoma
Biosample name: CJM
Data source: NCBI GEO/SRA
GSE ID: GSE75352
Cancer type: melanoma
CRC number: 128
TF number of all CRCs: 31
TF list of all CRCs: ETS1, SOX10, SOX5, MEF2D, SMAD3, RARG, TFAP2A, LEF1, TFAP2C, FOXD3, RARA, JUNB, FOXD2, NR4A1, POU2F1, KLF4, SREBF1, ETV4, SP1, PRRX1, MEOX2, TEAD1, RFX3, EHF, FOXJ3, NR2F2, BHLHE40, GLI3, NFATC2, TCF7L2, MAF

The most representative CRC of CJM
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Relationship plot of CRC model
TF number of this CRC: 10
CRC socre: 86.4
TF list of the most representative CRC
TF name TF family Frequency of TFs
ETS1 ETS 128 / 128
FOXD3 Fork_head 69 / 128
MEF2D SRF 90 / 128
POU2F1 Pou 51 / 128
PRRX1 Homeobox 31 / 128
RARA THR-like 62 / 128
RARG THR-like 90 / 128
SMAD3 MH1 90 / 128
SOX10 HMG 128 / 128
SOX5 HMG 125 / 128

All CRCs of CJM
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CRC rank TF list of CRCs CRC score TF number of CRC Detail of CRC

Frequency of TFs that appear in CRCs
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TF name Frequency of TFs TF family Ensembl ID
SOX10 128 / 128 HMG ENSG00000100146
ETS1 128 / 128 ETS ENSG00000134954
SOX5 125 / 128 HMG ENSG00000134532
RARG 90 / 128 THR-like ENSG00000172819
SMAD3 90 / 128 MH1 ENSG00000166949
MEF2D 90 / 128 SRF ENSG00000116604
TFAP2A 80 / 128 AP-2 ENSG00000137203
LEF1 80 / 128 HMG ENSG00000138795
TFAP2C 74 / 128 AP-2 ENSG00000087510
FOXD3 69 / 128 Fork_head ENSG00000187140
RARA 62 / 128 THR-like ENSG00000131759
JUNB 61 / 128 TF_bZIP ENSG00000171223
FOXD2 59 / 128 Fork_head ENSG00000186564
NR4A1 55 / 128 NGFIB-like ENSG00000123358
POU2F1 51 / 128 Pou ENSG00000143190
KLF4 40 / 128 zf-C2H2 ENSG00000136826
SREBF1 39 / 128 bHLH ENSG00000072310
ETV4 38 / 128 ETS ENSG00000175832
SP1 37 / 128 zf-C2H2 ENSG00000185591
PRRX1 31 / 128 Homeobox ENSG00000116132
MEOX2 27 / 128 Homeobox ENSG00000106511
TEAD1 26 / 128 TEA ENSG00000187079
RFX3 22 / 128 RFX ENSG00000080298
EHF 18 / 128 ETS ENSG00000135373
BHLHE40 12 / 128 bHLH ENSG00000134107
FOXJ3 12 / 128 Fork_head ENSG00000198815
NR2F2 12 / 128 RXR-like ENSG00000185551
GLI3 9 / 128 zf-C2H2 ENSG00000106571
NFATC2 9 / 128 RHD ENSG00000101096
TCF7L2 5 / 128 HMG ENSG00000148737
MAF 3 / 128 TF_bZIP ENSG00000178573

Indegree and outdegree of TFs
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TF name Indegree Outdegree Node connections
NFATC2 42 42 84
JUNB 39 57 96
SMAD3 42 57 99
SOX10 42 61 103
BHLHE40 40 47 87
TEAD1 32 58 90
RFX3 28 48 76
ETS1 40 62 102
MEOX2 23 51 74
SOX5 41 59 100
RARA 38 59 97
RARG 39 59 98
GLI3 27 51 78
TFAP2A 41 60 101
TFAP2C 38 55 93
NR2F2 39 45 84
KLF4 34 54 88
FOXJ3 27 62 89
SP1 36 57 93
NR4A1 39 52 91
FOXD2 37 53 90
FOXD3 38 59 97
EHF 25 62 87
LEF1 39 55 94
ETV4 35 52 87
TCF7L2 23 56 79
SREBF1 41 51 92
MEF2D 34 58 92
PRRX1 24 52 76
MAF 14 61 75
POU2F1 32 60 92

Expression of TFs in all CRCs